PubMed:10764840
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1218-1224 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | fucose |
| T2 | 1280-1285 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Le(x) |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1218-1224 | Glycan_Motif | denotes | fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T2 | 1280-1285 | Glycan_Motif | denotes | Le(x) | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 357-368 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood cells |
| T2 | 357-362 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T3 | 885-893 | http://purl.obolibrary.org/obo/MAT_0000032 | denotes | skeleton |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-149 | Sentence | denotes | Unusual N-glycosylation of a recombinant human erythropoietin expressed in a human lymphoblastoid cell line does not alter its biological properties. |
| TextSentencer_T2 | 150-369 | Sentence | denotes | Erythropoietin (Epo) is a 166 amino acids protein containing three N-glycosylation sites (Asn-24, Asn-38, and Asn-83) and 1 O- glycosylation site (Ser-126) and involved in the regulation of the level of red blood cells. |
| TextSentencer_T3 | 370-498 | Sentence | denotes | Today, only one recombinant human Epo (rHuEpo), produced in CHO cell line, is extensively used in therapy to cure severe anemia. |
| TextSentencer_T4 | 499-648 | Sentence | denotes | The structure of the glycan chains of this rHuEpo slightly differ of those of the urinary human Epo (uHuEpo), considered as the natural Epo molecule. |
| TextSentencer_T5 | 649-795 | Sentence | denotes | In an attempt to produce a rHuEpo as close as possible to the uHuEpo, Epo gene was expressed in a human lymphoblastoid cell line, named RPMI 1788. |
| TextSentencer_T6 | 796-934 | Sentence | denotes | In order to fully characterize the Epo-RPMI, structural characterizations of the protein skeleton as well as glycan chains were undergone. |
| TextSentencer_T7 | 935-1016 | Sentence | denotes | As expected, the amino acid sequence of the Epo-RPMI conformed to that of uHuEpo. |
| TextSentencer_T8 | 1017-1140 | Sentence | denotes | Surprisingly, the structure of some N-glycan chains, as mainly determined by ESI-MS, revealed some unusual characteristics. |
| TextSentencer_T9 | 1141-1365 | Sentence | denotes | Thus, 80% of N-glycans possess a bisecting GlcNAc residue, 25% bear a second fucose residue which is present, in a large part, in a sialyl Le(x)motif, and 13% contain more than three LacNAc repeats (up to five per molecule). |
| TextSentencer_T10 | 1366-1537 | Sentence | denotes | Despite these unusual structural characteristics, the data concerning the in vitro and in vivo biological activities were not impaired when compared to Epo-CHO and uHuEpo. |
| T1 | 0-149 | Sentence | denotes | Unusual N-glycosylation of a recombinant human erythropoietin expressed in a human lymphoblastoid cell line does not alter its biological properties. |
| T2 | 150-369 | Sentence | denotes | Erythropoietin (Epo) is a 166 amino acids protein containing three N-glycosylation sites (Asn-24, Asn-38, and Asn-83) and 1 O- glycosylation site (Ser-126) and involved in the regulation of the level of red blood cells. |
| T3 | 370-498 | Sentence | denotes | Today, only one recombinant human Epo (rHuEpo), produced in CHO cell line, is extensively used in therapy to cure severe anemia. |
| T4 | 499-648 | Sentence | denotes | The structure of the glycan chains of this rHuEpo slightly differ of those of the urinary human Epo (uHuEpo), considered as the natural Epo molecule. |
| T5 | 649-795 | Sentence | denotes | In an attempt to produce a rHuEpo as close as possible to the uHuEpo, Epo gene was expressed in a human lymphoblastoid cell line, named RPMI 1788. |
| T6 | 796-934 | Sentence | denotes | In order to fully characterize the Epo-RPMI, structural characterizations of the protein skeleton as well as glycan chains were undergone. |
| T7 | 935-1016 | Sentence | denotes | As expected, the amino acid sequence of the Epo-RPMI conformed to that of uHuEpo. |
| T8 | 1017-1140 | Sentence | denotes | Surprisingly, the structure of some N-glycan chains, as mainly determined by ESI-MS, revealed some unusual characteristics. |
| T9 | 1141-1365 | Sentence | denotes | Thus, 80% of N-glycans possess a bisecting GlcNAc residue, 25% bear a second fucose residue which is present, in a large part, in a sialyl Le(x)motif, and 13% contain more than three LacNAc repeats (up to five per molecule). |
| T10 | 1366-1537 | Sentence | denotes | Despite these unusual structural characteristics, the data concerning the in vitro and in vivo biological activities were not impaired when compared to Epo-CHO and uHuEpo. |
| T1 | 0-149 | Sentence | denotes | Unusual N-glycosylation of a recombinant human erythropoietin expressed in a human lymphoblastoid cell line does not alter its biological properties. |
| T2 | 150-369 | Sentence | denotes | Erythropoietin (Epo) is a 166 amino acids protein containing three N-glycosylation sites (Asn-24, Asn-38, and Asn-83) and 1 O- glycosylation site (Ser-126) and involved in the regulation of the level of red blood cells. |
| T3 | 370-498 | Sentence | denotes | Today, only one recombinant human Epo (rHuEpo), produced in CHO cell line, is extensively used in therapy to cure severe anemia. |
| T4 | 499-648 | Sentence | denotes | The structure of the glycan chains of this rHuEpo slightly differ of those of the urinary human Epo (uHuEpo), considered as the natural Epo molecule. |
| T5 | 649-795 | Sentence | denotes | In an attempt to produce a rHuEpo as close as possible to the uHuEpo, Epo gene was expressed in a human lymphoblastoid cell line, named RPMI 1788. |
| T6 | 796-934 | Sentence | denotes | In order to fully characterize the Epo-RPMI, structural characterizations of the protein skeleton as well as glycan chains were undergone. |
| T7 | 935-1016 | Sentence | denotes | As expected, the amino acid sequence of the Epo-RPMI conformed to that of uHuEpo. |
| T8 | 1017-1140 | Sentence | denotes | Surprisingly, the structure of some N-glycan chains, as mainly determined by ESI-MS, revealed some unusual characteristics. |
| T9 | 1141-1365 | Sentence | denotes | Thus, 80% of N-glycans possess a bisecting GlcNAc residue, 25% bear a second fucose residue which is present, in a large part, in a sialyl Le(x)motif, and 13% contain more than three LacNAc repeats (up to five per molecule). |
| T10 | 1366-1537 | Sentence | denotes | Despite these unusual structural characteristics, the data concerning the in vitro and in vivo biological activities were not impaired when compared to Epo-CHO and uHuEpo. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1218-1224 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | fucose |
| T2 | 1280-1285 | https://glytoucan.org/Structures/Glycans/G01187XC | denotes | Le(x) |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 491-497 | HP_0001903 | denotes | anemia |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 353-368 | http://purl.bioontology.org/ontology/ICD10/R71 | denotes | red blood cells |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 83-97 | FMAID:197290 | denotes | lymphoblastoid |
| _T2 | 83-97 | FMAID:83030 | denotes | lymphoblastoid |
| _T3 | 83-102 | FMAID:198000 | denotes | lymphoblastoid cell |
| _T4 | 83-102 | FMAID:84065 | denotes | lymphoblastoid cell |
| _T5 | 180-191 | FMAID:82739 | denotes | amino acids |
| _T6 | 180-191 | FMAID:196728 | denotes | amino acids |
| _T7 | 192-199 | FMAID:165447 | denotes | protein |
| _T8 | 192-199 | FMAID:67257 | denotes | protein |
| _T9 | 353-368 | FMAID:167136 | denotes | red blood cells |
| _T10 | 357-362 | FMAID:256053 | denotes | blood |
| _T11 | 357-368 | FMAID:62844 | denotes | blood cells |
| _T12 | 357-368 | FMAID:167135 | denotes | blood cells |
| _T13 | 363-368 | FMAID:68646 | denotes | cells |
| _T14 | 363-368 | FMAID:169002 | denotes | cells |
| _T15 | 723-727 | FMAID:198663 | denotes | gene |
| _T16 | 753-767 | FMAID:83030 | denotes | lymphoblastoid |
| _T17 | 753-767 | FMAID:197290 | denotes | lymphoblastoid |
| _T18 | 753-772 | FMAID:84065 | denotes | lymphoblastoid cell |
| _T19 | 753-772 | FMAID:198000 | denotes | lymphoblastoid cell |
| _T20 | 877-884 | FMAID:67257 | denotes | protein |
| _T21 | 877-884 | FMAID:165447 | denotes | protein |
| _T22 | 885-893 | FMAID:116478 | denotes | skeleton |
| _T23 | 885-893 | FMAID:23875 | denotes | skeleton |
| _T24 | 952-962 | FMAID:196728 | denotes | amino acid |
| _T25 | 952-962 | FMAID:82739 | denotes | amino acid |
| _T26 | 1218-1224 | FMAID:196784 | denotes | fucose |
| _T27 | 1218-1224 | FMAID:82790 | denotes | fucose |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 47-61 | http://www.uniprot.org/uniprot/P01588 | denotes | erythropoietin |
| T2 | 150-164 | http://www.uniprot.org/uniprot/P01588 | denotes | Erythropoietin |
| T3 | 186-210 | http://www.uniprot.org/uniprot/P23434 | denotes | acids protein containing |
| T4 | 186-210 | http://www.uniprot.org/uniprot/Q96QF7 | denotes | acids protein containing |
| T5 | 1094-1097 | http://www.uniprot.org/uniprot/P19957 | denotes | ESI |
| T6 | 1098-1100 | http://www.uniprot.org/uniprot/Q99707 | denotes | MS |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 47-61 | http://www.uniprot.org/uniprot/P07321 | denotes | erythropoietin |
| T2 | 150-164 | http://www.uniprot.org/uniprot/P07321 | denotes | Erythropoietin |
| T3 | 1098-1100 | http://www.uniprot.org/uniprot/A6H5Y3 | denotes | MS |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 363-368 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T2 | 952-971 | http://purl.bioontology.org/ontology/STY/T087 | denotes | amino acid sequence |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 10-23 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T2 | 219-232 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T3 | 277-290 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T4 | 180-199 | http://purl.obolibrary.org/obo/GO_0018032 | denotes | amino acids protein |
| T5 | 180-199 | http://purl.obolibrary.org/obo/GO_0006477 | denotes | amino acids protein |
| T6 | 180-199 | http://purl.obolibrary.org/obo/GO_0017013 | denotes | amino acids protein |
| T7 | 180-199 | http://purl.obolibrary.org/obo/GO_0018079 | denotes | amino acids protein |
| T8 | 180-199 | http://purl.obolibrary.org/obo/GO_0018260 | denotes | amino acids protein |
| T9 | 180-199 | http://purl.obolibrary.org/obo/GO_0018180 | denotes | amino acids protein |
| T10 | 180-199 | http://purl.obolibrary.org/obo/GO_0018344 | denotes | amino acids protein |
| T11 | 180-199 | http://purl.obolibrary.org/obo/GO_0018345 | denotes | amino acids protein |
| T12 | 180-199 | http://purl.obolibrary.org/obo/GO_0018214 | denotes | amino acids protein |
| T13 | 180-199 | http://purl.obolibrary.org/obo/GO_0035601 | denotes | amino acids protein |
| T14 | 326-336 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T15 | 430-433 | http://purl.obolibrary.org/obo/GO_0043848 | denotes | CHO |
| T16 | 1522-1525 | http://purl.obolibrary.org/obo/GO_0043848 | denotes | CHO |
| T17 | 723-741 | http://purl.obolibrary.org/obo/GO_0010467 | denotes | gene was expressed |
| T18 | 1273-1279 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialyl |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 47-61 | http://purl.obolibrary.org/obo/GO_0005128 | denotes | erythropoietin |
| T2 | 150-164 | http://purl.obolibrary.org/obo/GO_0005128 | denotes | Erythropoietin |
| T3 | 180-199 | http://purl.obolibrary.org/obo/GO_0005515 | denotes | amino acids protein |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 98-102 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T2 | 434-438 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T3 | 363-368 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T4 | 297-300 | http://purl.obolibrary.org/obo/GO_0005790 | denotes | Ser |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 357-362 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T2 | 448-459 | http://purl.obolibrary.org/obo/UBERON_2000106 | denotes | extensively |
| T3 | 885-893 | http://purl.obolibrary.org/obo/UBERON_0004288 | denotes | skeleton |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 41-46 | http://edamontology.org/topic_2815 | denotes | human |
| T2 | 77-82 | http://edamontology.org/topic_2815 | denotes | human |
| T3 | 180-191 | http://edamontology.org/topic_0154 | denotes | amino acids |
| T4 | 192-199 | http://edamontology.org/topic_0078 | denotes | protein |
| T5 | 398-403 | http://edamontology.org/topic_2815 | denotes | human |
| T6 | 589-594 | http://edamontology.org/topic_2815 | denotes | human |
| T7 | 639-647 | http://edamontology.org/topic_2839 | denotes | molecule |
| T8 | 723-741 | http://edamontology.org/topic_0203 | denotes | gene was expressed |
| T9 | 747-752 | http://edamontology.org/topic_2815 | denotes | human |
| T10 | 877-884 | http://edamontology.org/topic_0078 | denotes | protein |
| T11 | 952-962 | http://edamontology.org/topic_0154 | denotes | amino acid |
| T12 | 963-971 | http://edamontology.org/topic_0080 | denotes | sequence |
| T13 | 963-971 | http://edamontology.org/topic_3168 | denotes | sequence |
| T14 | 1285-1290 | http://edamontology.org/topic_0158 | denotes | motif |
| T15 | 1355-1363 | http://edamontology.org/topic_2839 | denotes | molecule |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 192-199 | http://edamontology.org/format_1208 | denotes | protein |
| T2 | 192-199 | http://edamontology.org/data_1467 | denotes | protein |
| T3 | 192-210 | http://edamontology.org/data_1467 | denotes | protein containing |
| T4 | 503-512 | http://edamontology.org/data_0883 | denotes | structure |
| T5 | 768-784 | http://edamontology.org/data_2316 | denotes | cell line, named |
| T6 | 779-784 | http://edamontology.org/data_2099 | denotes | named |
| T7 | 841-851 | http://edamontology.org/data_0883 | denotes | structural |
| T8 | 877-884 | http://edamontology.org/data_1467 | denotes | protein |
| T9 | 877-884 | http://edamontology.org/format_1208 | denotes | protein |
| T10 | 963-971 | http://edamontology.org/data_2044 | denotes | sequence |
| T11 | 963-971 | http://edamontology.org/operation_3218 | denotes | sequence |
| T12 | 1035-1044 | http://edamontology.org/data_0883 | denotes | structure |
| T13 | 1191-1198 | http://edamontology.org/data_1756 | denotes | residue |
| T14 | 1225-1232 | http://edamontology.org/data_1756 | denotes | residue |
| T15 | 1388-1398 | http://edamontology.org/data_0883 | denotes | structural |
| T16 | 1420-1424 | http://edamontology.org/data_0006 | denotes | data |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 1184-1190 | chem:24139 | denotes | GlcNAc |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 357-362 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T2 | 357-362 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T3 | 357-368 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood cells |
| T4 | 885-893 | http://purl.obolibrary.org/obo/MAT_0000032 | denotes | skeleton |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1053-1061 | http://rdf.glycoinfo.org/glycan/G00027MO | denotes | N-glycan |
| T2 | 1154-1163 | http://rdf.glycoinfo.org/glycan/G00027MO | denotes | N-glycans |
GlycoBiology-Epitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoEpitope-B_T1 | 301-304 | http://www.glycoepitope.jp/epitopes/AN0580 | denotes | 126 |
GlyTouCan-IUPAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| GlycanIUPAC_T1 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G26693XF" | denotes | GlcNAc |
| GlycanIUPAC_T2 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G01864SU" | denotes | GlcNAc |
| GlycanIUPAC_T3 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G17605FD" | denotes | GlcNAc |
| GlycanIUPAC_T4 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G41950LU" | denotes | GlcNAc |
| GlycanIUPAC_T5 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G57195RJ" | denotes | GlcNAc |
| GlycanIUPAC_T6 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G85391SA" | denotes | GlcNAc |
| GlycanIUPAC_T7 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G89565QL" | denotes | GlcNAc |
| GlycanIUPAC_T8 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G80869MR" | denotes | GlcNAc |
| GlycanIUPAC_T9 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G55978NL" | denotes | GlcNAc |
| GlycanIUPAC_T10 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G54644LT" | denotes | GlcNAc |
| GlycanIUPAC_T11 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G25694UG" | denotes | GlcNAc |
| GlycanIUPAC_T12 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G25126RB" | denotes | GlcNAc |
| GlycanIUPAC_T13 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G51848AD" | denotes | GlcNAc |
| GlycanIUPAC_T14 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G94667GM" | denotes | GlcNAc |
| GlycanIUPAC_T15 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G30124BO" | denotes | GlcNAc |
| GlycanIUPAC_T16 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G82777EZ" | denotes | GlcNAc |
| GlycanIUPAC_T17 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G10151YZ" | denotes | GlcNAc |
| GlycanIUPAC_T18 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G17585ZM" | denotes | GlcNAc |
| GlycanIUPAC_T19 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G04411CJ" | denotes | GlcNAc |
| GlycanIUPAC_T20 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G38254HJ" | denotes | GlcNAc |
| GlycanIUPAC_T21 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G75188FS" | denotes | GlcNAc |
| GlycanIUPAC_T22 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G70374VG" | denotes | GlcNAc |
| GlycanIUPAC_T23 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G45176LJ" | denotes | GlcNAc |
| GlycanIUPAC_T24 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G30874VW" | denotes | GlcNAc |
| GlycanIUPAC_T25 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G69333MI" | denotes | GlcNAc |
| GlycanIUPAC_T26 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G10676XO" | denotes | GlcNAc |
| GlycanIUPAC_T27 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G14843DJ" | denotes | GlcNAc |
| GlycanIUPAC_T28 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G47546FR" | denotes | GlcNAc |
| GlycanIUPAC_T29 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G73695ZM" | denotes | GlcNAc |
| GlycanIUPAC_T30 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G31923TJ" | denotes | GlcNAc |
| GlycanIUPAC_T31 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G60519EP" | denotes | GlcNAc |
| GlycanIUPAC_T32 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G07933IA" | denotes | GlcNAc |
| GlycanIUPAC_T33 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G40745NH" | denotes | GlcNAc |
| GlycanIUPAC_T34 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G54496YV" | denotes | GlcNAc |
| GlycanIUPAC_T35 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G62953SQ" | denotes | GlcNAc |
| GlycanIUPAC_T36 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G70070AY" | denotes | GlcNAc |
| GlycanIUPAC_T37 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G78792WC" | denotes | GlcNAc |
| GlycanIUPAC_T38 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G25238AV" | denotes | GlcNAc |
| GlycanIUPAC_T39 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G40510DP" | denotes | GlcNAc |
| GlycanIUPAC_T40 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G61120TK" | denotes | GlcNAc |
| GlycanIUPAC_T41 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G41342KV" | denotes | GlcNAc |
| GlycanIUPAC_T42 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G90703NA" | denotes | GlcNAc |
| GlycanIUPAC_T43 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G01591HR" | denotes | GlcNAc |
| GlycanIUPAC_T44 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G56520XN" | denotes | GlcNAc |
| GlycanIUPAC_T45 | 1184-1190 | "http://rdf.glycoinfo.org/glycan/G81830JX" | denotes | GlcNAc |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 357-362 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| PD-UBERON-AE-B_T2 | 885-893 | http://purl.obolibrary.org/obo/UBERON_0004288 | denotes | skeleton |
| PD-UBERON-AE-B_T3 | 448-459 | http://purl.obolibrary.org/obo/UBERON_2000106 | denotes | extensively |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1324-1330 | Glycan | denotes | LacNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G66213AR |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 491-497 | Disease | denotes | anemia | http://purl.obolibrary.org/obo/MONDO_0002280 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 357-368 | Body_part | denotes | blood cells | http://purl.obolibrary.org/obo/MAT_0000083 |
| T2 | 885-893 | Body_part | denotes | skeleton | http://purl.obolibrary.org/obo/MAT_0000032 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 491-497 | Phenotype | denotes | anemia | HP:0001903 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 1324-1330 | Glycan | denotes | LacNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G66213AR |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 491-497 | Phenotype | denotes | anemia | HP:0001903 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 353-368 | Cell | denotes | red blood cells | http://purl.obolibrary.org/obo/CL:0000232|http://purl.obolibrary.org/obo/CL:0000562|http://purl.obolibrary.org/obo/CL:0000595 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 353-368 | Body_part | denotes | red blood cells | http://purl.obolibrary.org/obo/CL_0000232|http://purl.obolibrary.org/obo/CL_0000562|http://purl.obolibrary.org/obo/CL_0000595 |
| T4 | 885-893 | Body_part | denotes | skeleton | http://purl.obolibrary.org/obo/UBERON_0004288 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 491-497 | Disease | denotes | anemia | MONDO:0002280 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 41-46 | Organism | denotes | human | 9606 |
| T2 | 77-82 | Organism | denotes | human | 9606 |
| T3 | 398-403 | Organism | denotes | human | 9606 |
| T4 | 491-497 | Organism | denotes | anemia | 12939 |
| T5 | 589-594 | Organism | denotes | human | 9606 |
| T6 | 747-752 | Organism | denotes | human | 9606 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-149 | Sentence | denotes | Unusual N-glycosylation of a recombinant human erythropoietin expressed in a human lymphoblastoid cell line does not alter its biological properties. |
| T2 | 150-369 | Sentence | denotes | Erythropoietin (Epo) is a 166 amino acids protein containing three N-glycosylation sites (Asn-24, Asn-38, and Asn-83) and 1 O- glycosylation site (Ser-126) and involved in the regulation of the level of red blood cells. |
| T3 | 370-498 | Sentence | denotes | Today, only one recombinant human Epo (rHuEpo), produced in CHO cell line, is extensively used in therapy to cure severe anemia. |
| T4 | 499-648 | Sentence | denotes | The structure of the glycan chains of this rHuEpo slightly differ of those of the urinary human Epo (uHuEpo), considered as the natural Epo molecule. |
| T5 | 649-795 | Sentence | denotes | In an attempt to produce a rHuEpo as close as possible to the uHuEpo, Epo gene was expressed in a human lymphoblastoid cell line, named RPMI 1788. |
| T6 | 796-934 | Sentence | denotes | In order to fully characterize the Epo-RPMI, structural characterizations of the protein skeleton as well as glycan chains were undergone. |
| T7 | 935-1016 | Sentence | denotes | As expected, the amino acid sequence of the Epo-RPMI conformed to that of uHuEpo. |
| T8 | 1017-1140 | Sentence | denotes | Surprisingly, the structure of some N-glycan chains, as mainly determined by ESI-MS, revealed some unusual characteristics. |
| T9 | 1141-1365 | Sentence | denotes | Thus, 80% of N-glycans possess a bisecting GlcNAc residue, 25% bear a second fucose residue which is present, in a large part, in a sialyl Le(x)motif, and 13% contain more than three LacNAc repeats (up to five per molecule). |
| T10 | 1366-1537 | Sentence | denotes | Despite these unusual structural characteristics, the data concerning the in vitro and in vivo biological activities were not impaired when compared to Epo-CHO and uHuEpo. |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 353-368 | Body_part | denotes | red blood cells | FMA:62845 |
| T2 | 885-893 | Body_part | denotes | skeleton | FMA:303630 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 357-368 | Body_part | denotes | blood cells | http://purl.obolibrary.org/obo/MAT_0000083 |
| T2 | 885-893 | Body_part | denotes | skeleton | http://purl.obolibrary.org/obo/MAT_0000032 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 41-46 | OrganismTaxon | denotes | human | 9606 |
| T2 | 77-82 | OrganismTaxon | denotes | human | 9606 |
| T3 | 398-403 | OrganismTaxon | denotes | human | 9606 |
| T4 | 491-497 | OrganismTaxon | denotes | anemia | 12939 |
| T5 | 589-594 | OrganismTaxon | denotes | human | 9606 |
| T6 | 747-752 | OrganismTaxon | denotes | human | 9606 |
| T7 | 1204-1210 | OrganismTaxon | denotes | bear a | 1231991 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 353-368 | Body_part | denotes | red blood cells | http://purl.obolibrary.org/obo/CL_0000232|http://purl.obolibrary.org/obo/CL_0000562|http://purl.obolibrary.org/obo/CL_0000595 |
| T4 | 885-893 | Body_part | denotes | skeleton | http://purl.obolibrary.org/obo/UBERON_0004288 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 353-368 | Cell | denotes | red blood cells | http://purl.obolibrary.org/obo/CL:0000232|http://purl.obolibrary.org/obo/CL:0000562|http://purl.obolibrary.org/obo/CL:0000595 |