PubMed:10764830
Annnotations
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-63 | Sentence | denotes | Remodeling of sugar chain structures of human interferon-gamma. |
| TextSentencer_T2 | 64-193 | Sentence | denotes | Natural human interferon (IFN)-gamma has mainly biantennary complex-type sugar chains and scarcely has multiantennary structures. |
| TextSentencer_T3 | 194-285 | Sentence | denotes | We attempted to remodel the sugar chain structures using IFN-gamma as a model glycoprotein. |
| TextSentencer_T4 | 286-628 | Sentence | denotes | To obtain the branching glycoforms of IFN-gamma, we introduced the genes for GnT-IV (UDP-N-acetylglucosamine:alpha-1,3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase) and/or GnT-V (UDP-N-acetylglucosamine:alpha-1,6-D-mannoside beta-1, 6-N-acetylglucosaminyltransferase) into Chinese hamster ovary (CHO) cells producing human IFN-gamma. |
| TextSentencer_T5 | 629-708 | Sentence | denotes | The parental CHO cells produced IFN-gamma with biantennary sugar chains mainly. |
| TextSentencer_T6 | 709-856 | Sentence | denotes | When the GnT-IV activity was increased, triantennary sugar chains with a branch produced by GnT-IV increased up to 66.9% of the total sugar chains. |
| TextSentencer_T7 | 857-998 | Sentence | denotes | When the GnT-V activity was increased, triantennary sugar chains with a corresponding branch increased up to 55.7% of the total sugar chains. |
| TextSentencer_T8 | 999-1135 | Sentence | denotes | When the GnT-IV and -V activities were increased at a time, tetraantennary sugar chains increased up to 56.2% of the total sugar chains. |
| TextSentencer_T9 | 1136-1250 | Sentence | denotes | The proportion of these multiantennary sugar chains corresponded to the intracellular activities of GnT-IV and -V. |
| TextSentencer_T10 | 1251-1529 | Sentence | denotes | What is more, lectin blot and flow cytometric analysis indicated that the multi-branch structure of the sugar chains was increased not only on IFN-gamma, one of the secretory glycoproteins, but also on almost CHO cellular proteins by introducing either or both of the GnT genes. |
| TextSentencer_T11 | 1530-1672 | Sentence | denotes | The results suggest that the branching structure of sugar chains of glycoproteins could be controlled by cellular GnT-IV and GnT-V activities. |
| TextSentencer_T12 | 1673-1801 | Sentence | denotes | This technology can produce glycoforms out of natural occurrence, which should enlarge the potency of glycoprotein therapeutics. |
| T1 | 0-63 | Sentence | denotes | Remodeling of sugar chain structures of human interferon-gamma. |
| T2 | 64-193 | Sentence | denotes | Natural human interferon (IFN)-gamma has mainly biantennary complex-type sugar chains and scarcely has multiantennary structures. |
| T3 | 194-285 | Sentence | denotes | We attempted to remodel the sugar chain structures using IFN-gamma as a model glycoprotein. |
| T4 | 286-628 | Sentence | denotes | To obtain the branching glycoforms of IFN-gamma, we introduced the genes for GnT-IV (UDP-N-acetylglucosamine:alpha-1,3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase) and/or GnT-V (UDP-N-acetylglucosamine:alpha-1,6-D-mannoside beta-1, 6-N-acetylglucosaminyltransferase) into Chinese hamster ovary (CHO) cells producing human IFN-gamma. |
| T5 | 629-708 | Sentence | denotes | The parental CHO cells produced IFN-gamma with biantennary sugar chains mainly. |
| T6 | 709-856 | Sentence | denotes | When the GnT-IV activity was increased, triantennary sugar chains with a branch produced by GnT-IV increased up to 66.9% of the total sugar chains. |
| T7 | 857-998 | Sentence | denotes | When the GnT-V activity was increased, triantennary sugar chains with a corresponding branch increased up to 55.7% of the total sugar chains. |
| T8 | 999-1135 | Sentence | denotes | When the GnT-IV and -V activities were increased at a time, tetraantennary sugar chains increased up to 56.2% of the total sugar chains. |
| T9 | 1136-1529 | Sentence | denotes | The proportion of these multiantennary sugar chains corresponded to the intracellular activities of GnT-IV and -V. What is more, lectin blot and flow cytometric analysis indicated that the multi-branch structure of the sugar chains was increased not only on IFN-gamma, one of the secretory glycoproteins, but also on almost CHO cellular proteins by introducing either or both of the GnT genes. |
| T10 | 1530-1672 | Sentence | denotes | The results suggest that the branching structure of sugar chains of glycoproteins could be controlled by cellular GnT-IV and GnT-V activities. |
| T11 | 1673-1801 | Sentence | denotes | This technology can produce glycoforms out of natural occurrence, which should enlarge the potency of glycoprotein therapeutics. |
| T1 | 0-63 | Sentence | denotes | Remodeling of sugar chain structures of human interferon-gamma. |
| T2 | 64-193 | Sentence | denotes | Natural human interferon (IFN)-gamma has mainly biantennary complex-type sugar chains and scarcely has multiantennary structures. |
| T3 | 194-285 | Sentence | denotes | We attempted to remodel the sugar chain structures using IFN-gamma as a model glycoprotein. |
| T4 | 286-628 | Sentence | denotes | To obtain the branching glycoforms of IFN-gamma, we introduced the genes for GnT-IV (UDP-N-acetylglucosamine:alpha-1,3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase) and/or GnT-V (UDP-N-acetylglucosamine:alpha-1,6-D-mannoside beta-1, 6-N-acetylglucosaminyltransferase) into Chinese hamster ovary (CHO) cells producing human IFN-gamma. |
| T5 | 629-708 | Sentence | denotes | The parental CHO cells produced IFN-gamma with biantennary sugar chains mainly. |
| T6 | 709-856 | Sentence | denotes | When the GnT-IV activity was increased, triantennary sugar chains with a branch produced by GnT-IV increased up to 66.9% of the total sugar chains. |
| T7 | 857-998 | Sentence | denotes | When the GnT-V activity was increased, triantennary sugar chains with a corresponding branch increased up to 55.7% of the total sugar chains. |
| T8 | 999-1135 | Sentence | denotes | When the GnT-IV and -V activities were increased at a time, tetraantennary sugar chains increased up to 56.2% of the total sugar chains. |
| T9 | 1136-1250 | Sentence | denotes | The proportion of these multiantennary sugar chains corresponded to the intracellular activities of GnT-IV and -V. |
| T10 | 1251-1529 | Sentence | denotes | What is more, lectin blot and flow cytometric analysis indicated that the multi-branch structure of the sugar chains was increased not only on IFN-gamma, one of the secretory glycoproteins, but also on almost CHO cellular proteins by introducing either or both of the GnT genes. |
| T11 | 1530-1672 | Sentence | denotes | The results suggest that the branching structure of sugar chains of glycoproteins could be controlled by cellular GnT-IV and GnT-V activities. |
| T12 | 1673-1801 | Sentence | denotes | This technology can produce glycoforms out of natural occurrence, which should enlarge the potency of glycoprotein therapeutics. |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 14-19 | FMAID:196724 | denotes | sugar |
| _T2 | 137-142 | FMAID:196724 | denotes | sugar |
| _T3 | 222-227 | FMAID:196724 | denotes | sugar |
| _T4 | 272-284 | FMAID:62925 | denotes | glycoprotein |
| _T5 | 272-284 | FMAID:167256 | denotes | glycoprotein |
| _T6 | 300-309 | FMAID:226027 | denotes | branching |
| _T7 | 300-309 | FMAID:226028 | denotes | branching |
| _T8 | 353-358 | FMAID:198663 | denotes | genes |
| _T9 | 375-394 | FMAID:196781 | denotes | N-acetylglucosamine |
| _T10 | 375-394 | FMAID:82787 | denotes | N-acetylglucosamine |
| _T11 | 478-497 | FMAID:196781 | denotes | N-acetylglucosamine |
| _T12 | 478-497 | FMAID:82787 | denotes | N-acetylglucosamine |
| _T13 | 584-589 | FMAID:7209 | denotes | ovary |
| _T14 | 584-589 | FMAID:93687 | denotes | ovary |
| _T15 | 596-601 | FMAID:68646 | denotes | cells |
| _T16 | 596-601 | FMAID:169002 | denotes | cells |
| _T17 | 646-651 | FMAID:68646 | denotes | cells |
| _T18 | 646-651 | FMAID:169002 | denotes | cells |
| _T19 | 688-693 | FMAID:196724 | denotes | sugar |
| _T20 | 762-767 | FMAID:196724 | denotes | sugar |
| _T21 | 782-788 | FMAID:226027 | denotes | branch |
| _T22 | 782-788 | FMAID:226028 | denotes | branch |
| _T23 | 843-848 | FMAID:196724 | denotes | sugar |
| _T24 | 909-914 | FMAID:196724 | denotes | sugar |
| _T25 | 943-949 | FMAID:226028 | denotes | branch |
| _T26 | 943-949 | FMAID:226027 | denotes | branch |
| _T27 | 985-990 | FMAID:196724 | denotes | sugar |
| _T28 | 1074-1079 | FMAID:196724 | denotes | sugar |
| _T29 | 1122-1127 | FMAID:196724 | denotes | sugar |
| _T30 | 1175-1180 | FMAID:196724 | denotes | sugar |
| _T31 | 1331-1337 | FMAID:226027 | denotes | branch |
| _T32 | 1331-1337 | FMAID:226028 | denotes | branch |
| _T33 | 1355-1360 | FMAID:196724 | denotes | sugar |
| _T34 | 1426-1439 | FMAID:62925 | denotes | glycoproteins |
| _T35 | 1426-1439 | FMAID:167256 | denotes | glycoproteins |
| _T36 | 1473-1481 | FMAID:67257 | denotes | proteins |
| _T37 | 1473-1481 | FMAID:165447 | denotes | proteins |
| _T38 | 1523-1528 | FMAID:198663 | denotes | genes |
| _T39 | 1559-1568 | FMAID:226028 | denotes | branching |
| _T40 | 1559-1568 | FMAID:226027 | denotes | branching |
| _T41 | 1582-1587 | FMAID:196724 | denotes | sugar |
| _T42 | 1598-1611 | FMAID:62925 | denotes | glycoproteins |
| _T43 | 1598-1611 | FMAID:167256 | denotes | glycoproteins |
| _T44 | 1775-1787 | FMAID:62925 | denotes | glycoprotein |
| _T45 | 1775-1787 | FMAID:167256 | denotes | glycoprotein |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 46-62 | http://www.uniprot.org/uniprot/P01579 | denotes | interferon-gamma |
| T2 | 90-100 | http://www.uniprot.org/uniprot/P01579 | denotes | IFN)-gamma |
| T3 | 251-260 | http://www.uniprot.org/uniprot/P01579 | denotes | IFN-gamma |
| T4 | 324-333 | http://www.uniprot.org/uniprot/P01579 | denotes | IFN-gamma |
| T5 | 618-627 | http://www.uniprot.org/uniprot/P01579 | denotes | IFN-gamma |
| T6 | 661-670 | http://www.uniprot.org/uniprot/P01579 | denotes | IFN-gamma |
| T7 | 1394-1403 | http://www.uniprot.org/uniprot/P01579 | denotes | IFN-gamma |
| T8 | 417-423 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta-1 |
| T9 | 520-526 | http://www.uniprot.org/uniprot/Q92988 | denotes | beta-1 |
| T10 | 427-458 | http://www.uniprot.org/uniprot/Q06430 | denotes | N-acetylglucosaminyltransferase |
| T11 | 530-561 | http://www.uniprot.org/uniprot/Q06430 | denotes | N-acetylglucosaminyltransferase |
| T12 | 427-458 | http://www.uniprot.org/uniprot/Q8N0V5 | denotes | N-acetylglucosaminyltransferase |
| T13 | 530-561 | http://www.uniprot.org/uniprot/Q8N0V5 | denotes | N-acetylglucosaminyltransferase |
| T14 | 427-458 | http://www.uniprot.org/uniprot/Q8NFS9 | denotes | N-acetylglucosaminyltransferase |
| T15 | 530-561 | http://www.uniprot.org/uniprot/Q8NFS9 | denotes | N-acetylglucosaminyltransferase |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 46-62 | http://www.uniprot.org/uniprot/P01580 | denotes | interferon-gamma |
| T2 | 90-100 | http://www.uniprot.org/uniprot/P01580 | denotes | IFN)-gamma |
| T3 | 251-260 | http://www.uniprot.org/uniprot/P01580 | denotes | IFN-gamma |
| T4 | 324-333 | http://www.uniprot.org/uniprot/P01580 | denotes | IFN-gamma |
| T5 | 618-627 | http://www.uniprot.org/uniprot/P01580 | denotes | IFN-gamma |
| T6 | 661-670 | http://www.uniprot.org/uniprot/P01580 | denotes | IFN-gamma |
| T7 | 1394-1403 | http://www.uniprot.org/uniprot/P01580 | denotes | IFN-gamma |
| T8 | 427-458 | http://www.uniprot.org/uniprot/P97402 | denotes | N-acetylglucosaminyltransferase |
| T9 | 530-561 | http://www.uniprot.org/uniprot/P97402 | denotes | N-acetylglucosaminyltransferase |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 417-421 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T2 | 417-421 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T3 | 520-524 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T4 | 520-524 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T5 | 596-601 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
| T6 | 646-651 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 591-594 | http://purl.obolibrary.org/obo/GO_0043848 | denotes | CHO |
| T2 | 642-645 | http://purl.obolibrary.org/obo/GO_0043848 | denotes | CHO |
| T3 | 1460-1463 | http://purl.obolibrary.org/obo/GO_0043848 | denotes | CHO |
| T4 | 1464-1472 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
| T5 | 1635-1643 | http://purl.obolibrary.org/obo/GO_0007349 | denotes | cellular |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 46-62 | http://purl.obolibrary.org/obo/GO_0005133 | denotes | interferon-gamma |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 596-601 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T2 | 646-651 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3 | 1208-1221 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 40-45 | http://edamontology.org/topic_2815 | denotes | human |
| T2 | 72-77 | http://edamontology.org/topic_2815 | denotes | human |
| T3 | 612-617 | http://edamontology.org/topic_2815 | denotes | human |
| T4 | 1473-1481 | http://edamontology.org/topic_0078 | denotes | proteins |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-36 | http://edamontology.org/data_0883 | denotes | structures |
| T2 | 182-192 | http://edamontology.org/data_0883 | denotes | structures |
| T3 | 234-244 | http://edamontology.org/data_0883 | denotes | structures |
| T4 | 1297-1305 | http://edamontology.org/operation_2945 | denotes | analysis |
| T5 | 1338-1347 | http://edamontology.org/data_0883 | denotes | structure |
| T6 | 1473-1481 | http://edamontology.org/data_1467 | denotes | proteins |
| T7 | 1473-1481 | http://edamontology.org/format_1208 | denotes | proteins |
| T8 | 1569-1578 | http://edamontology.org/data_0883 | denotes | structure |
GlyTouCan-IUPAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| GlycanIUPAC_T1 | 14-19 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T2 | 137-142 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T3 | 222-227 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T4 | 688-693 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T5 | 762-767 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T6 | 843-848 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T7 | 909-914 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T8 | 985-990 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T9 | 1074-1079 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T10 | 1122-1127 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T11 | 1175-1180 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T12 | 1355-1360 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T13 | 1582-1587 | "http://rdf.glycoinfo.org/glycan/G59665TO" | denotes | sugar |
| GlycanIUPAC_T14 | 14-19 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T15 | 137-142 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T16 | 222-227 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T17 | 688-693 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T18 | 762-767 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T19 | 843-848 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T20 | 909-914 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T21 | 985-990 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T22 | 1074-1079 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T23 | 1122-1127 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T24 | 1175-1180 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T25 | 1355-1360 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T26 | 1582-1587 | "http://rdf.glycoinfo.org/glycan/G32915EI" | denotes | sugar |
| GlycanIUPAC_T27 | 14-19 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T28 | 137-142 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T29 | 222-227 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T30 | 688-693 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T31 | 762-767 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T32 | 843-848 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T33 | 909-914 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T34 | 985-990 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T35 | 1074-1079 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T36 | 1122-1127 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T37 | 1175-1180 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T38 | 1355-1360 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
| GlycanIUPAC_T39 | 1582-1587 | "http://rdf.glycoinfo.org/glycan/G60625TS" | denotes | sugar |
Lectin-Jamboree
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1265-1271 | lectin | denotes | lectin |
Lectin-Jamboree-Sentence
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-63 | Sentence | denotes | Remodeling of sugar chain structures of human interferon-gamma. |
| T2 | 64-193 | Sentence | denotes | Natural human interferon (IFN)-gamma has mainly biantennary complex-type sugar chains and scarcely has multiantennary structures. |
| T3 | 194-285 | Sentence | denotes | We attempted to remodel the sugar chain structures using IFN-gamma as a model glycoprotein. |
| T4 | 286-628 | Sentence | denotes | To obtain the branching glycoforms of IFN-gamma, we introduced the genes for GnT-IV (UDP-N-acetylglucosamine:alpha-1,3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase) and/or GnT-V (UDP-N-acetylglucosamine:alpha-1,6-D-mannoside beta-1, 6-N-acetylglucosaminyltransferase) into Chinese hamster ovary (CHO) cells producing human IFN-gamma. |
| T5 | 629-708 | Sentence | denotes | The parental CHO cells produced IFN-gamma with biantennary sugar chains mainly. |
| T6 | 709-856 | Sentence | denotes | When the GnT-IV activity was increased, triantennary sugar chains with a branch produced by GnT-IV increased up to 66.9% of the total sugar chains. |
| T7 | 857-998 | Sentence | denotes | When the GnT-V activity was increased, triantennary sugar chains with a corresponding branch increased up to 55.7% of the total sugar chains. |
| T8 | 999-1135 | Sentence | denotes | When the GnT-IV and -V activities were increased at a time, tetraantennary sugar chains increased up to 56.2% of the total sugar chains. |
| T9 | 1136-1529 | Sentence | denotes | The proportion of these multiantennary sugar chains corresponded to the intracellular activities of GnT-IV and -V. What is more, lectin blot and flow cytometric analysis indicated that the multi-branch structure of the sugar chains was increased not only on IFN-gamma, one of the secretory glycoproteins, but also on almost CHO cellular proteins by introducing either or both of the GnT genes. |
| T10 | 1530-1672 | Sentence | denotes | The results suggest that the branching structure of sugar chains of glycoproteins could be controlled by cellular GnT-IV and GnT-V activities. |
| T11 | 1673-1801 | Sentence | denotes | This technology can produce glycoforms out of natural occurrence, which should enlarge the potency of glycoprotein therapeutics. |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 40-45 | OrganismTaxon | denotes | human | 9606 |
| T2 | 72-77 | OrganismTaxon | denotes | human | 9606 |
| T3 | 568-583 | OrganismTaxon | denotes | Chinese hamster | 10029 |
| T4 | 612-617 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 584-589 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T2 | 1208-1221 | Body_part | denotes | intracellular | http://purl.obolibrary.org/obo/GO_0005622 |