PubMed:10753916
Annnotations
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 644-650 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T2 | 652-658 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T3 | 752-758 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T4 | 1058-1064 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T5 | 1134-1140 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T6 | 1239-1245 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T7 | 1395-1401 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T8 | 1494-1500 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 106-112 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
| T2 | 155-161 | Glycan_Motif | denotes | Core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
| T3 | 345-351 | Glycan_Motif | denotes | Core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
| T4 | 886-892 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
| T5 | 941-947 | Glycan_Motif | denotes | core 1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
| T6 | 997-1003 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
| T7 | 1084-1095 | Glycan_Motif | denotes | leukosialin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G78436BB|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G50850NI |
| T9 | 1186-1192 | Glycan_Motif | denotes | core 2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 644-650 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T2 | 652-658 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T3 | 752-758 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T4 | 1058-1064 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T5 | 1134-1140 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T6 | 1239-1245 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T7 | 1395-1401 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| T8 | 1494-1500 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 941-947 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | core 1 |
| T2 | 1084-1095 | https://glytoucan.org/Structures/Glycans/G50850NI | denotes | leukosialin |
| T3 | 1084-1095 | https://glytoucan.org/Structures/Glycans/G78436BB | denotes | leukosialin |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-37 | Sentence | denotes | Control of O-glycan branch formation. |
| T2 | 38-154 | Sentence | denotes | Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n-acetylglucosaminyltransferase. |
| T3 | 155-344 | Sentence | denotes | Core 2 O-glycan branching catalyzed by UDP-N-acetyl-alpha-D-glucosamine: acceptor beta1, 6-N-acetylglucosaminyltransferases (beta6GlcNAc-Ts) is an important step in mucin-type biosynthesis. |
| T4 | 345-480 | Sentence | denotes | Core 2 complex-type O-glycans are involved in selectin-mediated adhesion events, and O-glycan branching appears to be highly regulated. |
| T5 | 481-651 | Sentence | denotes | Two homologous beta6GlcNAc-Ts functioning in O-glycan branching have previously been characterized, and here we report a third homologous beta6GlcNAc-T designated C2GnT3. |
| T6 | 652-725 | Sentence | denotes | C2GnT3 was identified by BLAST analysis of human genome survey sequences. |
| T7 | 726-854 | Sentence | denotes | The catalytic activity of C2GnT3 was evaluated by in vitro analysis of a secreted form of the protein expressed in insect cells. |
| T8 | 855-916 | Sentence | denotes | The results revealed exclusive core 2 beta6GlcNAc-T activity. |
| T9 | 917-1021 | Sentence | denotes | The product formed with core 1-para-nitrophenyl was confirmed by (1)H NMR to be core 2-para-nitrophenyl. |
| T10 | 1022-1234 | Sentence | denotes | In vivo analysis of the function of C2GnT3 by coexpression of leukosialin (CD43) and a full coding construct of C2GnT3 in Chinese hamster ovary cells confirmed the core 2 activity and failed to reveal I activity. |
| T11 | 1235-1325 | Sentence | denotes | The C2GnT3 gene was located to 5q12, and the coding region was contained in a single exon. |
| T12 | 1326-1460 | Sentence | denotes | Northern analysis revealed selectively high levels of a 5.5-kilobase C2GnT3 transcript in thymus with only low levels in other organs. |
| T13 | 1461-1616 | Sentence | denotes | The unique expression pattern of C2GnT3 suggests that this enzyme serves a specific function different from other members of the beta6GlcNAc-T gene family. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 88-94 | http://purl.obolibrary.org/obo/MAT_0000080 | denotes | thymus |
| T2 | 1416-1422 | http://purl.obolibrary.org/obo/MAT_0000080 | denotes | thymus |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 633-643 | url | denotes | designated |
| PD-GlycoGenes20190927-B_T2 | 644-650 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| PD-GlycoGenes20190927-B_T3 | 652-658 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| PD-GlycoGenes20190927-B_T4 | 752-758 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| PD-GlycoGenes20190927-B_T5 | 1058-1064 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| PD-GlycoGenes20190927-B_T6 | 1134-1140 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| PD-GlycoGenes20190927-B_T7 | 1239-1245 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| PD-GlycoGenes20190927-B_T8 | 1395-1401 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
| PD-GlycoGenes20190927-B_T9 | 1494-1500 | https://acgg.asia/db/ggdb/info/gg110 | denotes | C2GnT3 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 106-112 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T2 | 886-892 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T3 | 941-947 | Glycan | denotes | core 1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T4 | 997-1003 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T5 | 1186-1192 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 106-112 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T2 | 155-161 | Glycan | denotes | Core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T3 | 345-351 | Glycan | denotes | Core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T4 | 886-892 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T5 | 941-947 | Glycan | denotes | core 1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T6 | 997-1003 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T7 | 1186-1192 | Glycan | denotes | core 2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 88-94 | Organism | denotes | thymus | 49990 |
| T2 | 695-700 | Organism | denotes | human | 9606 |
| T3 | 1144-1159 | Organism | denotes | Chinese hamster | 10029 |
| T4 | 1416-1422 | Organism | denotes | thymus | 49990 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-37 | Sentence | denotes | Control of O-glycan branch formation. |
| T2 | 38-154 | Sentence | denotes | Molecular cloning and characterization of a novel thymus-associated core 2 beta1, 6-n-acetylglucosaminyltransferase. |
| T3 | 155-344 | Sentence | denotes | Core 2 O-glycan branching catalyzed by UDP-N-acetyl-alpha-D-glucosamine: acceptor beta1, 6-N-acetylglucosaminyltransferases (beta6GlcNAc-Ts) is an important step in mucin-type biosynthesis. |
| T4 | 345-480 | Sentence | denotes | Core 2 complex-type O-glycans are involved in selectin-mediated adhesion events, and O-glycan branching appears to be highly regulated. |
| T5 | 481-651 | Sentence | denotes | Two homologous beta6GlcNAc-Ts functioning in O-glycan branching have previously been characterized, and here we report a third homologous beta6GlcNAc-T designated C2GnT3. |
| T6 | 652-725 | Sentence | denotes | C2GnT3 was identified by BLAST analysis of human genome survey sequences. |
| T7 | 726-854 | Sentence | denotes | The catalytic activity of C2GnT3 was evaluated by in vitro analysis of a secreted form of the protein expressed in insect cells. |
| T8 | 855-916 | Sentence | denotes | The results revealed exclusive core 2 beta6GlcNAc-T activity. |
| T9 | 917-1021 | Sentence | denotes | The product formed with core 1-para-nitrophenyl was confirmed by (1)H NMR to be core 2-para-nitrophenyl. |
| T10 | 1022-1234 | Sentence | denotes | In vivo analysis of the function of C2GnT3 by coexpression of leukosialin (CD43) and a full coding construct of C2GnT3 in Chinese hamster ovary cells confirmed the core 2 activity and failed to reveal I activity. |
| T11 | 1235-1325 | Sentence | denotes | The C2GnT3 gene was located to 5q12, and the coding region was contained in a single exon. |
| T12 | 1326-1460 | Sentence | denotes | Northern analysis revealed selectively high levels of a 5.5-kilobase C2GnT3 transcript in thymus with only low levels in other organs. |
| T13 | 1461-1616 | Sentence | denotes | The unique expression pattern of C2GnT3 suggests that this enzyme serves a specific function different from other members of the beta6GlcNAc-T gene family. |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 88-94 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T2 | 1160-1165 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T3 | 1416-1422 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 88-94 | Body_part | denotes | thymus | FMA:9607 |
| T2 | 701-707 | Body_part | denotes | genome | FMA:84116 |
| T3 | 1160-1165 | Body_part | denotes | ovary | FMA:7209 |
| T4 | 1416-1422 | Body_part | denotes | thymus | FMA:9607 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 88-94 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T2 | 1416-1422 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 88-94 | OrganismTaxon | denotes | thymus | 49990 |
| T2 | 695-700 | OrganismTaxon | denotes | human | 9606 |
| T3 | 1144-1159 | OrganismTaxon | denotes | Chinese hamster | 10029 |
| T4 | 1416-1422 | OrganismTaxon | denotes | thymus | 49990 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 88-94 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
| T2 | 1416-1422 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/MAT_0000080 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 88-94 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |
| T2 | 1160-1165 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T3 | 1416-1422 | Body_part | denotes | thymus | http://purl.obolibrary.org/obo/UBERON_0002370 |