PubMed:10747952
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 55-64 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T3 | 512-525 | Glycan_Motif | denotes | P(k) antigens | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00059MO |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-65 | Sentence | denotes | Cloning and expression of the histo-blood group Pk UDP-galactose: |
| T2 | 66-120 | Sentence | denotes | Ga1beta-4G1cbeta1-cer alpha1, 4-galactosyltransferase. |
| T3 | 121-164 | Sentence | denotes | Molecular genetic basis of the p phenotype. |
| T4 | 165-338 | Sentence | denotes | The molecular genetic basis of the P histo-blood group system has eluded characterization despite extensive studies of the biosynthesis of the P(1), P, and P(k) glycolipids. |
| T5 | 339-526 | Sentence | denotes | The main controversy has been whether a single or two distinct UDP-Gal:Galbeta1-R 4-alpha-galactosyltransferases catalyze the syntheses of the structurally related P(1) and P(k) antigens. |
| T6 | 527-574 | Sentence | denotes | The P(1) polymorphism is linked to 22q11.3-ter. |
| T7 | 575-718 | Sentence | denotes | Data base searches with the coding region of an alpha4GlcNAc-transferase identified a novel homologous gene at 22q13.2 designated alpha4Gal-T1. |
| T8 | 719-844 | Sentence | denotes | Expression of full coding constructs of alpha4Gal-T1 in insect cells revealed it encoded P(k) but not P(1) synthase activity. |
| T9 | 845-984 | Sentence | denotes | Northern analysis showed expression of the transcript correlating with P(k) synthase activity and antigen expression in human B cell lines. |
| T10 | 985-1082 | Sentence | denotes | Transfection of P(k)-negative Namalwa cells with alpha4Gal-T1 resulted in strong P(k) expression. |
| T11 | 1083-1246 | Sentence | denotes | A single homozygous missense mutation, M183K, was found in six Swedish individuals of the rare p phenotype, confirming that alpha4Gal-T1 represented the P(k) gene. |
| T12 | 1247-1387 | Sentence | denotes | Sequence analysis of the coding region of alpha4Gal-T1 in P(1)+/- individuals did not reveal polymorphisms correlating with P(1)P(2) typing. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 55-64 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T2 | 55-64 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
| T3 | 512-525 | https://glytoucan.org/Structures/Glycans/G00059MO | denotes | P(k) antigens |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 36-41 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T2 | 36-41 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T3 | 208-213 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T4 | 208-213 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 88-119 | https://acgg.asia/db/ggdb/info/gg068 | denotes | alpha1, 4-galactosyltransferase |
| PD-GlycoGenes20190927-B_T2 | 227-230 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
| PD-GlycoGenes20190927-B_T3 | 360-363 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
| PD-GlycoGenes20190927-B_T4 | 694-704 | url | denotes | designated |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 965-970 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 36-41 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 208-213 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T3 | 971-977 | Body_part | denotes | B cell | http://purl.obolibrary.org/obo/CL_0000236 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 36-41 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 208-213 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 971-977 | Cell | denotes | B cell | http://purl.obolibrary.org/obo/CL:0000236 |