PubMed:10747950
Annnotations
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 86-95 | Glycan_Motif | denotes | T antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T2 | 594-603 | Glycan_Motif | denotes | T antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T3 | 605-608 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T4 | 692-695 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T5 | 812-815 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T6 | 889-892 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T7 | 981-984 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T8 | 1148-1151 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T9 | 1258-1261 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
T10 | 1275-1278 | Glycan_Motif | denotes | Tag | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-162 | Sentence | denotes | Protein-protein interactions of the primase subunits p58 and p48 with simian virus 40 T antigen are required for efficient primer synthesis in a cell-free system. |
T2 | 163-318 | Sentence | denotes | DNA polymerase alpha-primase (pol-prim, consisting of p180-p68-p58-p48), and primase p58-p48 (prim(2)) synthesize short RNA primers on single-stranded DNA. |
T3 | 319-492 | Sentence | denotes | In the SV40 DNA replication system, only pol-prim is able to start leading strand DNA replication that needs unwinding of double-stranded (ds) DNA prior to primer synthesis. |
T4 | 493-610 | Sentence | denotes | At high concentrations, pol-prim and prim(2) indistinguishably reduce the unwinding of dsDNA by SV40 T antigen (Tag). |
T5 | 611-801 | Sentence | denotes | RNA primer synthesis on ssDNA in the presence of replication protein A (RPA) and Tag has served as a model system to study the initiation of Okazaki fragments on the lagging strand in vitro. |
T6 | 802-888 | Sentence | denotes | On ssDNA, Tag stimulates whereas RPA inhibits the initiation reaction of both enzymes. |
T7 | 889-960 | Sentence | denotes | Tag reverses and even overcompensates the inhibition of primase by RPA. |
T8 | 961-1065 | Sentence | denotes | Physical binding of Tag to the primase subunits and RPA, respectively, is required for these activities. |
T9 | 1066-1190 | Sentence | denotes | Each subunit of the primase complex, p58 and p48, performs physical contacts with Tag and RPA independently of p180 and p68. |
T10 | 1191-1353 | Sentence | denotes | Using surface plasmon resonance, the dissociation constants of the Tag/pol-prim and Tag/primase interactions were 1.2 x 10(-8) m and 1.3 x 10(-8) m, respectively. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 86-95 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
T2 | 594-603 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | T antigen |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 86-95 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
T2 | 594-603 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | T antigen |
T3 | 605-608 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
T4 | 692-695 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
T5 | 812-815 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
T6 | 889-892 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
T7 | 981-984 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
T8 | 1148-1151 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
T9 | 1258-1261 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
T10 | 1275-1278 | http://www.glycoepitope.jp/epitopes/EP0020 | denotes | Tag |
Glycan-GlyCosmos
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 86-95 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T2 | 594-603 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T3 | 605-608 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T4 | 692-695 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T5 | 812-815 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T6 | 889-892 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T7 | 981-984 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T8 | 1148-1151 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T9 | 1258-1261 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T10 | 1275-1278 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
GlyCosmos-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 86-95 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
T2 | 594-603 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
T3 | 605-608 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T4 | 692-695 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T5 | 812-815 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T6 | 889-892 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T7 | 981-984 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T8 | 1148-1151 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T9 | 1258-1261 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T10 | 1275-1278 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
GlyCosmos15-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 70-85 | OrganismTaxon | denotes | simian virus 40 | 1891767 |
T2 | 197-201 | OrganismTaxon | denotes | prim | 13597 |
T3 | 257-261 | OrganismTaxon | denotes | prim | 13597 |
T4 | 364-368 | OrganismTaxon | denotes | prim | 13597 |
T5 | 521-525 | OrganismTaxon | denotes | prim | 13597 |
T6 | 530-534 | OrganismTaxon | denotes | prim | 13597 |
T7 | 1266-1270 | OrganismTaxon | denotes | prim | 13597 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-162 | Sentence | denotes | Protein-protein interactions of the primase subunits p58 and p48 with simian virus 40 T antigen are required for efficient primer synthesis in a cell-free system. |
T2 | 163-318 | Sentence | denotes | DNA polymerase alpha-primase (pol-prim, consisting of p180-p68-p58-p48), and primase p58-p48 (prim(2)) synthesize short RNA primers on single-stranded DNA. |
T3 | 319-492 | Sentence | denotes | In the SV40 DNA replication system, only pol-prim is able to start leading strand DNA replication that needs unwinding of double-stranded (ds) DNA prior to primer synthesis. |
T4 | 493-610 | Sentence | denotes | At high concentrations, pol-prim and prim(2) indistinguishably reduce the unwinding of dsDNA by SV40 T antigen (Tag). |
T5 | 611-801 | Sentence | denotes | RNA primer synthesis on ssDNA in the presence of replication protein A (RPA) and Tag has served as a model system to study the initiation of Okazaki fragments on the lagging strand in vitro. |
T6 | 802-888 | Sentence | denotes | On ssDNA, Tag stimulates whereas RPA inhibits the initiation reaction of both enzymes. |
T7 | 889-960 | Sentence | denotes | Tag reverses and even overcompensates the inhibition of primase by RPA. |
T8 | 961-1065 | Sentence | denotes | Physical binding of Tag to the primase subunits and RPA, respectively, is required for these activities. |
T9 | 1066-1190 | Sentence | denotes | Each subunit of the primase complex, p58 and p48, performs physical contacts with Tag and RPA independently of p180 and p68. |
T10 | 1191-1353 | Sentence | denotes | Using surface plasmon resonance, the dissociation constants of the Tag/pol-prim and Tag/primase interactions were 1.2 x 10(-8) m and 1.3 x 10(-8) m, respectively. |
GlyCosmos15-Sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-162 | Sentence | denotes | Protein-protein interactions of the primase subunits p58 and p48 with simian virus 40 T antigen are required for efficient primer synthesis in a cell-free system. |
T2 | 163-318 | Sentence | denotes | DNA polymerase alpha-primase (pol-prim, consisting of p180-p68-p58-p48), and primase p58-p48 (prim(2)) synthesize short RNA primers on single-stranded DNA. |
T3 | 319-492 | Sentence | denotes | In the SV40 DNA replication system, only pol-prim is able to start leading strand DNA replication that needs unwinding of double-stranded (ds) DNA prior to primer synthesis. |
T4 | 493-610 | Sentence | denotes | At high concentrations, pol-prim and prim(2) indistinguishably reduce the unwinding of dsDNA by SV40 T antigen (Tag). |
T5 | 611-801 | Sentence | denotes | RNA primer synthesis on ssDNA in the presence of replication protein A (RPA) and Tag has served as a model system to study the initiation of Okazaki fragments on the lagging strand in vitro. |
T6 | 802-888 | Sentence | denotes | On ssDNA, Tag stimulates whereas RPA inhibits the initiation reaction of both enzymes. |
T7 | 889-960 | Sentence | denotes | Tag reverses and even overcompensates the inhibition of primase by RPA. |
T8 | 961-1065 | Sentence | denotes | Physical binding of Tag to the primase subunits and RPA, respectively, is required for these activities. |
T9 | 1066-1190 | Sentence | denotes | Each subunit of the primase complex, p58 and p48, performs physical contacts with Tag and RPA independently of p180 and p68. |
T10 | 1191-1353 | Sentence | denotes | Using surface plasmon resonance, the dissociation constants of the Tag/pol-prim and Tag/primase interactions were 1.2 x 10(-8) m and 1.3 x 10(-8) m, respectively. |
GlyCosmos15-Glycan
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 86-95 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T2 | 594-603 | Glycan | denotes | T antigen | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T3 | 605-608 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T4 | 692-695 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T5 | 812-815 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T6 | 889-892 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T7 | 981-984 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T8 | 1148-1151 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T9 | 1258-1261 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
T10 | 1275-1278 | Glycan | denotes | Tag | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
GlyCosmos15-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 86-95 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
T2 | 594-603 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | T antigen | http://www.glycoepitope.jp/epitopes/EP0020 |
T3 | 605-608 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T4 | 692-695 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T5 | 812-815 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T6 | 889-892 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T7 | 981-984 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T8 | 1148-1151 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T9 | 1258-1261 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
T10 | 1275-1278 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Tag | http://www.glycoepitope.jp/epitopes/EP0020 |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 70-85 | OrganismTaxon | denotes | simian virus 40 | 1891767 |
T2 | 197-201 | OrganismTaxon | denotes | prim | 13597 |
T3 | 257-261 | OrganismTaxon | denotes | prim | 13597 |
T4 | 364-368 | OrganismTaxon | denotes | prim | 13597 |
T5 | 521-525 | OrganismTaxon | denotes | prim | 13597 |
T6 | 530-534 | OrganismTaxon | denotes | prim | 13597 |
T7 | 1266-1270 | OrganismTaxon | denotes | prim | 13597 |