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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-146 Sentence denotes Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas.
T2 147-429 Sentence denotes Chromosomal translocations in human lipomas frequently create fusion transcripts encoding high mobility group (HMG) I-C DNA-binding domains and C-terminal sequences from different presumed transcription factors, suggesting a potential role for HMG I-C in the development of lipomas.
T3 430-561 Sentence denotes To evaluate the role of the HMG I-C component, the three DNA-binding domains of HMG I-C have now been expressed in transgenic mice.
T4 562-799 Sentence denotes Despite the ubiquitous expression of the truncated HMG I-C protein, the transgenic mice develop a selective abundance of fat tissue early in life, show marked adipose tissue inflammation, and have an abnormally high incidence of lipomas.
T5 800-980 Sentence denotes These findings demonstrate that the DNA-binding domains of HMG I-C, in the absence of a C-terminal fusion partner, are sufficient to perturb adipogenesis and predispose to lipomas.
T6 981-1179 Sentence denotes We provide data supporting the central utility of this animal model as a tool to understand the molecular mechanisms underlying the development of one of the most common kind of human benign tumors.
T1 0-146 Sentence denotes Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas.
T2 147-429 Sentence denotes Chromosomal translocations in human lipomas frequently create fusion transcripts encoding high mobility group (HMG) I-C DNA-binding domains and C-terminal sequences from different presumed transcription factors, suggesting a potential role for HMG I-C in the development of lipomas.
T3 430-561 Sentence denotes To evaluate the role of the HMG I-C component, the three DNA-binding domains of HMG I-C have now been expressed in transgenic mice.
T4 562-799 Sentence denotes Despite the ubiquitous expression of the truncated HMG I-C protein, the transgenic mice develop a selective abundance of fat tissue early in life, show marked adipose tissue inflammation, and have an abnormally high incidence of lipomas.
T5 800-980 Sentence denotes These findings demonstrate that the DNA-binding domains of HMG I-C, in the absence of a C-terminal fusion partner, are sufficient to perturb adipogenesis and predispose to lipomas.
T6 981-1179 Sentence denotes We provide data supporting the central utility of this animal model as a tool to understand the molecular mechanisms underlying the development of one of the most common kind of human benign tumors.

sentences

Id Subject Object Predicate Lexical cue
T1 0-146 Sentence denotes Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas.
T2 147-429 Sentence denotes Chromosomal translocations in human lipomas frequently create fusion transcripts encoding high mobility group (HMG) I-C DNA-binding domains and C-terminal sequences from different presumed transcription factors, suggesting a potential role for HMG I-C in the development of lipomas.
T3 430-561 Sentence denotes To evaluate the role of the HMG I-C component, the three DNA-binding domains of HMG I-C have now been expressed in transgenic mice.
T4 562-799 Sentence denotes Despite the ubiquitous expression of the truncated HMG I-C protein, the transgenic mice develop a selective abundance of fat tissue early in life, show marked adipose tissue inflammation, and have an abnormally high incidence of lipomas.
T5 800-980 Sentence denotes These findings demonstrate that the DNA-binding domains of HMG I-C, in the absence of a C-terminal fusion partner, are sufficient to perturb adipogenesis and predispose to lipomas.
T6 981-1179 Sentence denotes We provide data supporting the central utility of this animal model as a tool to understand the molecular mechanisms underlying the development of one of the most common kind of human benign tumors.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 683-693 http://purl.obolibrary.org/obo/MAT_0000015 denotes fat tissue
T2 721-735 http://purl.obolibrary.org/obo/MAT_0000015 denotes adipose tissue

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 183-190 HP_0012032 denotes lipomas
T2 421-428 HP_0012032 denotes lipomas
T3 791-798 HP_0012032 denotes lipomas
T4 972-979 HP_0012032 denotes lipomas
T5 1172-1178 HP_0002664 denotes tumors

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
10747931-4#59#64#gene3146 859-864 gene3146 denotes HMG I
10747931-4#59#64#gene10354 859-864 gene10354 denotes HMG I
10747931-4#172#179#diseaseC0023798 972-979 diseaseC0023798 denotes lipomas
59#64#gene3146172#179#diseaseC0023798 10747931-4#59#64#gene3146 10747931-4#172#179#diseaseC0023798 associated_with HMG I,lipomas
59#64#gene10354172#179#diseaseC0023798 10747931-4#59#64#gene10354 10747931-4#172#179#diseaseC0023798 associated_with HMG I,lipomas

NCBIDiseaseCorpus

Id Subject Object Predicate Lexical cue
T1 138-145 DiseaseClass:D008067 denotes lipomas
T2 183-190 DiseaseClass:D008067 denotes lipomas
T3 421-428 DiseaseClass:D008067 denotes lipomas
T4 721-748 SpecificDisease:D007249 denotes adipose tissue inflammation
T5 791-798 DiseaseClass:D008067 denotes lipomas
T6 972-979 DiseaseClass:D008067 denotes lipomas
T7 1165-1178 DiseaseClass:D009369 denotes benign tumors

DisGeNET

Id Subject Object Predicate Lexical cue
T0 613-618 gene:10354 denotes HMG I
T1 791-798 disease:C0023798 denotes lipomas
T2 613-618 gene:3146 denotes HMG I
T3 791-798 disease:C0023798 denotes lipomas
R1 T0 T1 associated_with HMG I,lipomas
R2 T2 T3 associated_with HMG I,lipomas

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 683-693 Body_part denotes fat tissue http://purl.obolibrary.org/obo/MAT_0000015
T2 721-735 Body_part denotes adipose tissue http://purl.obolibrary.org/obo/MAT_0000015

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 138-145 Phenotype denotes lipomas HP:0001012
T2 183-190 Phenotype denotes lipomas HP:0001012
T3 421-428 Phenotype denotes lipomas HP:0001012
T4 791-798 Phenotype denotes lipomas HP:0001012
T5 972-979 Phenotype denotes lipomas HP:0001012

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 736-748 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T2 1165-1178 Disease denotes benign tumors http://purl.obolibrary.org/obo/MONDO_0005165

NCBI-Disease-Train

Id Subject Object Predicate Lexical cue database_id
T3945 138-145 DiseaseClass denotes lipomas D008067
T3946 183-190 DiseaseClass denotes lipomas D008067
T3947 421-428 DiseaseClass denotes lipomas D008067
T3948 721-748 SpecificDisease denotes adipose tissue inflammation D007249
T3949 791-798 DiseaseClass denotes lipomas D008067
T3950 972-979 DiseaseClass denotes lipomas D008067
T3951 1165-1178 DiseaseClass denotes benign tumors D009369

NCBI-Disease-Corpus-All

Id Subject Object Predicate Lexical cue database_id
T3945 138-145 DiseaseClass denotes lipomas D008067
T3946 183-190 DiseaseClass denotes lipomas D008067
T3947 421-428 DiseaseClass denotes lipomas D008067
T3948 721-748 SpecificDisease denotes adipose tissue inflammation D007249
T3949 791-798 DiseaseClass denotes lipomas D008067
T3950 972-979 DiseaseClass denotes lipomas D008067
T3951 1165-1178 DiseaseClass denotes benign tumors D009369

NCBI-Disease-Corpus-2stage-All

Id Subject Object Predicate Lexical cue
T1 138-145 SpecificDisease denotes lipomas
T2 183-190 SpecificDisease denotes lipomas
T3 421-428 SpecificDisease denotes lipomas
T4 791-798 SpecificDisease denotes lipomas
T5 972-979 SpecificDisease denotes lipomas

NCBI-Disease-Corpus-rezarta-All

Id Subject Object Predicate Lexical cue
T1 138-145 SpecificDisease denotes lipomas
T2 183-190 SpecificDisease denotes lipomas
T3 421-428 SpecificDisease denotes lipomas
T4 791-798 SpecificDisease denotes lipomas
T5 972-979 SpecificDisease denotes lipomas

NCBI-Disease-Corpus-4oGuideline-All

Id Subject Object Predicate Lexical cue
T1 138-145 SpecificDisease denotes lipomas
T2 183-190 SpecificDisease denotes lipomas
T3 421-428 SpecificDisease denotes lipomas
T4 791-798 SpecificDisease denotes lipomas
T5 972-979 SpecificDisease denotes lipomas

NCBI-Disease-Corpus-Simple-All

Id Subject Object Predicate Lexical cue
T1 138-145 SpecificDisease denotes lipomas
T2 183-190 SpecificDisease denotes lipomas
T3 421-428 SpecificDisease denotes lipomas
T4 721-735 Modifier denotes adipose tissue
T5 791-798 SpecificDisease denotes lipomas
T6 972-979 SpecificDisease denotes lipomas
T7 1165-1171 Modifier denotes benign

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 11-15 OrganismTaxon denotes mice 10088
T2 177-182 OrganismTaxon denotes human 9606
T3 556-560 OrganismTaxon denotes mice 10088
T4 645-649 OrganismTaxon denotes mice 10088
T5 1159-1164 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 683-693 Body_part denotes fat tissue http://purl.obolibrary.org/obo/UBERON_0001013
T2 721-735 Body_part denotes adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013