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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-131 Sentence denotes Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: implication of the promoter sequence IL-5REIII.
TextSentencer_T2 132-391 Sentence denotes Our previous work demonstrated the capacity of galectin-3 (a beta-galactoside binding animal lectin) to inhibit IL-5 gene expression in different cell types, but the interaction of lectin with the cells and the pathways for the inhibition process are unknown.
TextSentencer_T3 392-473 Sentence denotes One of the purposes of this work was to study the cellular ligand for galectin-3.
TextSentencer_T4 474-719 Sentence denotes We have demonstrated that galectin-3 can bind to the low affinity IgG receptor (FcgammaRII or CD32) by using different experimental approaches, such as flow cytometry, fusion protein GST technology, and with a model of FcgammaRII-deficient mice.
TextSentencer_T5 720-873 Sentence denotes To further analyze the interaction between FcgammaRII and galectin-3, and its implication in IL-5 gene down-regulation we used FcgammaRII-deficient mice.
TextSentencer_T6 874-978 Sentence denotes When PBMC from these mice were incubated with galectin-3, the expression of the IL-5 gene was unchanged.
TextSentencer_T7 979-1121 Sentence denotes However, when PBMC from wild type mice and FcgammaRIII-deficient mice were incubated with galectin-3, IL-5 gene expression was down-regulated.
TextSentencer_T8 1122-1220 Sentence denotes Finally, we studied the implication of the negative regulatory sequence in the IL-5 gene promoter.
TextSentencer_T9 1221-1311 Sentence denotes In the presence of galectin-3, a DNA-protein complex was formed with the IL-5REIII region.
TextSentencer_T10 1312-1382 Sentence denotes This complex was not observed when unrelated oligonucleotide was used.
TextSentencer_T11 1383-1480 Sentence denotes So, galectin-3 induces a pathway, which activates a transcription factor that binds to IL-5REIII.
TextSentencer_T12 1481-1547 Sentence denotes This interaction is capable of inhibiting IL-5 gene transcription.
T1 0-131 Sentence denotes Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: implication of the promoter sequence IL-5REIII.
T2 132-391 Sentence denotes Our previous work demonstrated the capacity of galectin-3 (a beta-galactoside binding animal lectin) to inhibit IL-5 gene expression in different cell types, but the interaction of lectin with the cells and the pathways for the inhibition process are unknown.
T3 392-473 Sentence denotes One of the purposes of this work was to study the cellular ligand for galectin-3.
T4 474-719 Sentence denotes We have demonstrated that galectin-3 can bind to the low affinity IgG receptor (FcgammaRII or CD32) by using different experimental approaches, such as flow cytometry, fusion protein GST technology, and with a model of FcgammaRII-deficient mice.
T5 720-873 Sentence denotes To further analyze the interaction between FcgammaRII and galectin-3, and its implication in IL-5 gene down-regulation we used FcgammaRII-deficient mice.
T6 874-978 Sentence denotes When PBMC from these mice were incubated with galectin-3, the expression of the IL-5 gene was unchanged.
T7 979-1121 Sentence denotes However, when PBMC from wild type mice and FcgammaRIII-deficient mice were incubated with galectin-3, IL-5 gene expression was down-regulated.
T8 1122-1220 Sentence denotes Finally, we studied the implication of the negative regulatory sequence in the IL-5 gene promoter.
T9 1221-1311 Sentence denotes In the presence of galectin-3, a DNA-protein complex was formed with the IL-5REIII region.
T10 1312-1382 Sentence denotes This complex was not observed when unrelated oligonucleotide was used.
T11 1383-1480 Sentence denotes So, galectin-3 induces a pathway, which activates a transcription factor that binds to IL-5REIII.
T12 1481-1547 Sentence denotes This interaction is capable of inhibiting IL-5 gene transcription.
T1 0-131 Sentence denotes Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: implication of the promoter sequence IL-5REIII.
T2 132-391 Sentence denotes Our previous work demonstrated the capacity of galectin-3 (a beta-galactoside binding animal lectin) to inhibit IL-5 gene expression in different cell types, but the interaction of lectin with the cells and the pathways for the inhibition process are unknown.
T3 392-473 Sentence denotes One of the purposes of this work was to study the cellular ligand for galectin-3.
T4 474-719 Sentence denotes We have demonstrated that galectin-3 can bind to the low affinity IgG receptor (FcgammaRII or CD32) by using different experimental approaches, such as flow cytometry, fusion protein GST technology, and with a model of FcgammaRII-deficient mice.
T5 720-873 Sentence denotes To further analyze the interaction between FcgammaRII and galectin-3, and its implication in IL-5 gene down-regulation we used FcgammaRII-deficient mice.
T6 874-978 Sentence denotes When PBMC from these mice were incubated with galectin-3, the expression of the IL-5 gene was unchanged.
T7 979-1121 Sentence denotes However, when PBMC from wild type mice and FcgammaRIII-deficient mice were incubated with galectin-3, IL-5 gene expression was down-regulated.
T8 1122-1220 Sentence denotes Finally, we studied the implication of the negative regulatory sequence in the IL-5 gene promoter.
T9 1221-1311 Sentence denotes In the presence of galectin-3, a DNA-protein complex was formed with the IL-5REIII region.
T10 1312-1382 Sentence denotes This complex was not observed when unrelated oligonucleotide was used.
T11 1383-1480 Sentence denotes So, galectin-3 induces a pathway, which activates a transcription factor that binds to IL-5REIII.
T12 1481-1547 Sentence denotes This interaction is capable of inhibiting IL-5 gene transcription.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 78-82 FMAID:198663 denotes gene
_T2 249-253 FMAID:198663 denotes gene
_T3 329-334 FMAID:169002 denotes cells
_T4 329-334 FMAID:68646 denotes cells
_T5 540-543 FMAID:167179 denotes IgG
_T6 649-656 FMAID:165447 denotes protein
_T7 649-656 FMAID:67257 denotes protein
_T8 818-822 FMAID:198663 denotes gene
_T9 959-963 FMAID:198663 denotes gene
_T10 1086-1090 FMAID:198663 denotes gene
_T11 1174-1193 FMAID:198077 denotes regulatory sequence
_T12 1174-1193 FMAID:84122 denotes regulatory sequence
_T13 1206-1210 FMAID:198663 denotes gene
_T14 1258-1265 FMAID:67257 denotes protein
_T15 1258-1265 FMAID:165447 denotes protein
_T16 1258-1273 FMAID:85557 denotes protein complex
_T17 1258-1273 FMAID:199981 denotes protein complex
_T18 1258-1273 FMAID:165866 denotes protein complex
_T19 1258-1273 FMAID:67906 denotes protein complex
_T20 1528-1532 FMAID:198663 denotes gene

uniprot-human

Id Subject Object Predicate Lexical cue
T1 20-30 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T2 179-189 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T3 462-472 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T4 500-510 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T5 778-788 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T6 920-930 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T7 1069-1079 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T8 1240-1250 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T9 1387-1397 http://www.uniprot.org/uniprot/P17931 denotes galectin-3
T10 73-77 http://www.uniprot.org/uniprot/P05113 denotes IL-5
T11 244-248 http://www.uniprot.org/uniprot/P05113 denotes IL-5
T12 813-817 http://www.uniprot.org/uniprot/P05113 denotes IL-5
T13 954-958 http://www.uniprot.org/uniprot/P05113 denotes IL-5
T14 1081-1085 http://www.uniprot.org/uniprot/P05113 denotes IL-5
T15 1201-1205 http://www.uniprot.org/uniprot/P05113 denotes IL-5
T16 1523-1527 http://www.uniprot.org/uniprot/P05113 denotes IL-5
T17 568-572 http://www.uniprot.org/uniprot/P12318 denotes CD32
T18 568-572 http://www.uniprot.org/uniprot/P31994 denotes CD32
T19 568-572 http://www.uniprot.org/uniprot/P31995 denotes CD32
T20 657-660 http://www.uniprot.org/uniprot/Q86UG4 denotes GST
T21 1078-1083 http://www.uniprot.org/uniprot/P08700 denotes 3, IL
T22 1423-1455 http://www.uniprot.org/uniprot/Q3B7B7 denotes activates a transcription factor
T23 1423-1455 http://www.uniprot.org/uniprot/P18848 denotes activates a transcription factor
T24 1423-1455 http://www.uniprot.org/uniprot/Q9Y2D1 denotes activates a transcription factor
T25 1423-1455 http://www.uniprot.org/uniprot/P18847 denotes activates a transcription factor
T26 1423-1455 http://www.uniprot.org/uniprot/P18846 denotes activates a transcription factor
T27 1423-1455 http://www.uniprot.org/uniprot/P17544 denotes activates a transcription factor

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 20-30 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T2 179-189 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T3 462-472 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T4 500-510 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T5 778-788 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T6 920-930 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T7 1069-1079 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T8 1240-1250 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T9 1387-1397 http://www.uniprot.org/uniprot/P16110 denotes galectin-3
T10 73-77 http://www.uniprot.org/uniprot/P04401 denotes IL-5
T11 244-248 http://www.uniprot.org/uniprot/P04401 denotes IL-5
T12 813-817 http://www.uniprot.org/uniprot/P04401 denotes IL-5
T13 954-958 http://www.uniprot.org/uniprot/P04401 denotes IL-5
T14 1081-1085 http://www.uniprot.org/uniprot/P04401 denotes IL-5
T15 1201-1205 http://www.uniprot.org/uniprot/P04401 denotes IL-5
T16 1523-1527 http://www.uniprot.org/uniprot/P04401 denotes IL-5
T17 568-572 http://www.uniprot.org/uniprot/Q61558 denotes CD32
T18 1078-1083 http://www.uniprot.org/uniprot/P01586 denotes 3, IL

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 193-197 http://purl.bioontology.org/ontology/NCBITAXON/3554 denotes beta
T2 193-197 http://purl.bioontology.org/ontology/NCBITAXON/158455 denotes beta
T3 329-334 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 59-69 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T2 828-838 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T3 1111-1120 http://purl.obolibrary.org/obo/GO_0065007 denotes regulated
T4 249-264 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T5 1086-1101 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T6 442-450 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T7 1254-1273 http://purl.obolibrary.org/obo/GO_0001120 denotes DNA-protein complex
T8 1254-1273 http://purl.obolibrary.org/obo/GO_0015869 denotes DNA-protein complex
T9 1254-1273 http://purl.obolibrary.org/obo/GO_0065004 denotes DNA-protein complex
T10 1254-1273 http://purl.obolibrary.org/obo/GO_0032986 denotes DNA-protein complex
T11 1423-1455 http://purl.obolibrary.org/obo/GO_0006352 denotes activates a transcription factor
T12 1423-1455 http://purl.obolibrary.org/obo/GO_0032793 denotes activates a transcription factor
T13 1423-1455 http://purl.obolibrary.org/obo/GO_1901485 denotes activates a transcription factor
T14 1423-1455 http://purl.obolibrary.org/obo/GO_0043433 denotes activates a transcription factor
T15 1423-1455 http://purl.obolibrary.org/obo/GO_0051091 denotes activates a transcription factor
T16 1423-1455 http://purl.obolibrary.org/obo/GO_0000988 denotes activates a transcription factor
T17 1423-1455 http://purl.obolibrary.org/obo/GO_0001070 denotes activates a transcription factor
T18 1423-1455 http://purl.obolibrary.org/obo/GO_0001071 denotes activates a transcription factor
T19 1423-1455 http://purl.obolibrary.org/obo/GO_0003700 denotes activates a transcription factor
T20 1423-1455 http://purl.obolibrary.org/obo/GO_0051090 denotes activates a transcription factor
T21 1423-1466 http://purl.obolibrary.org/obo/GO_0000988 denotes activates a transcription factor that binds
T22 1435-1448 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T23 1533-1546 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

GO-MF

Id Subject Object Predicate Lexical cue
T1 73-77 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T2 244-248 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T3 813-817 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T4 954-958 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T5 1081-1085 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T6 1201-1205 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T7 1523-1527 http://purl.obolibrary.org/obo/GO_0005137 denotes IL-5
T8 198-217 http://purl.obolibrary.org/obo/GO_0016936 denotes galactoside binding
T9 210-217 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T10 515-519 http://purl.obolibrary.org/obo/GO_0070026 denotes bind
T11 1461-1466 http://purl.obolibrary.org/obo/GO_0070026 denotes binds
T12 210-217 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T13 515-519 http://purl.obolibrary.org/obo/GO_0003680 denotes bind
T14 1461-1466 http://purl.obolibrary.org/obo/GO_0003680 denotes binds
T15 210-217 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T16 515-519 http://purl.obolibrary.org/obo/GO_0017091 denotes bind
T17 1461-1466 http://purl.obolibrary.org/obo/GO_0017091 denotes binds
T18 210-217 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T19 515-519 http://purl.obolibrary.org/obo/GO_0005488 denotes bind
T20 1461-1466 http://purl.obolibrary.org/obo/GO_0005488 denotes binds
T21 451-457 http://purl.obolibrary.org/obo/GO_0005488 denotes ligand
T22 1078-1083 http://purl.obolibrary.org/obo/GO_0005135 denotes 3, IL
T23 1423-1466 http://purl.obolibrary.org/obo/GO_0033613 denotes activates a transcription factor that binds
T24 1461-1472 http://purl.obolibrary.org/obo/GO_0019955 denotes binds to IL

GO-CC

Id Subject Object Predicate Lexical cue
T1 278-282 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 329-334 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 1254-1273 http://purl.obolibrary.org/obo/GO_0001114 denotes DNA-protein complex
T4 1254-1273 http://purl.obolibrary.org/obo/GO_0032993 denotes DNA-protein complex
T5 1254-1273 http://purl.obolibrary.org/obo/GO_0097522 denotes DNA-protein complex
T6 1258-1273 http://purl.obolibrary.org/obo/GO_0043234 denotes protein complex

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 0-11 http://edamontology.org/topic_0602 denotes Interaction
T2 103-111 http://edamontology.org/topic_1312 denotes promoter
T3 103-111 http://edamontology.org/topic_0111 denotes promoter
T4 103-111 http://edamontology.org/topic_0749 denotes promoter
T5 112-120 http://edamontology.org/topic_0080 denotes sequence
T6 112-120 http://edamontology.org/topic_3168 denotes sequence
T7 249-264 http://edamontology.org/topic_0203 denotes gene expression
T8 298-309 http://edamontology.org/topic_0602 denotes interaction
T9 343-351 http://edamontology.org/topic_0602 denotes pathways
T10 432-437 http://edamontology.org/topic_3678 denotes study
T11 649-656 http://edamontology.org/topic_0078 denotes protein
T12 743-754 http://edamontology.org/topic_0602 denotes interaction
T13 818-838 http://edamontology.org/topic_0204 denotes gene down-regulation
T14 1086-1101 http://edamontology.org/topic_0203 denotes gene expression
T15 1134-1141 http://edamontology.org/topic_3678 denotes studied
T16 1185-1193 http://edamontology.org/topic_0080 denotes sequence
T17 1185-1193 http://edamontology.org/topic_3168 denotes sequence
T18 1211-1219 http://edamontology.org/topic_0111 denotes promoter
T19 1211-1219 http://edamontology.org/topic_1312 denotes promoter
T20 1211-1219 http://edamontology.org/topic_0749 denotes promoter
T21 1258-1265 http://edamontology.org/topic_0078 denotes protein
T22 1408-1415 http://edamontology.org/topic_0602 denotes pathway
T23 1435-1448 http://edamontology.org/topic_3308 denotes transcription
T24 1435-1448 http://edamontology.org/topic_0203 denotes transcription
T25 1435-1448 http://edamontology.org/topic_0110 denotes transcription
T26 1435-1448 http://edamontology.org/topic_3512 denotes transcription
T27 1435-1455 http://edamontology.org/topic_0749 denotes transcription factor
T28 1486-1497 http://edamontology.org/topic_0602 denotes interaction
T29 1528-1546 http://edamontology.org/topic_2399 denotes gene transcription
T30 1528-1546 http://edamontology.org/topic_3512 denotes gene transcription
T31 1533-1546 http://edamontology.org/topic_0203 denotes transcription
T32 1533-1546 http://edamontology.org/topic_0110 denotes transcription
T33 1533-1546 http://edamontology.org/topic_3512 denotes transcription
T34 1533-1546 http://edamontology.org/topic_3308 denotes transcription

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 112-120 http://edamontology.org/data_2044 denotes sequence
T2 112-120 http://edamontology.org/operation_3218 denotes sequence
T3 150-162 http://edamontology.org/operation_2246 denotes demonstrated
T4 249-267 http://edamontology.org/data_2967 denotes gene expression in
T5 283-288 http://edamontology.org/data_2100 denotes types
T6 343-351 http://edamontology.org/data_2600 denotes pathways
T7 371-378 http://edamontology.org/operation_0004 denotes process
T8 371-378 http://edamontology.org/operation_2409 denotes process
T9 482-494 http://edamontology.org/operation_2246 denotes demonstrated
T10 649-656 http://edamontology.org/format_1208 denotes protein
T11 649-656 http://edamontology.org/data_1467 denotes protein
T12 1086-1105 http://edamontology.org/data_2603 denotes gene expression was
T13 1185-1193 http://edamontology.org/data_2044 denotes sequence
T14 1185-1193 http://edamontology.org/operation_3218 denotes sequence
T15 1258-1265 http://edamontology.org/data_1467 denotes protein
T16 1258-1265 http://edamontology.org/format_1208 denotes protein
T17 1258-1273 http://edamontology.org/data_1461 denotes protein complex
T18 1258-1273 http://edamontology.org/data_2877 denotes protein complex
T19 1357-1372 http://edamontology.org/data_2718 denotes oligonucleotide
T20 1357-1372 http://edamontology.org/operation_3198 denotes oligonucleotide
T21 1408-1415 http://edamontology.org/data_2600 denotes pathway
T22 1435-1455 http://edamontology.org/data_2755 denotes transcription factor
T23 1435-1455 http://edamontology.org/data_2911 denotes transcription factor
T24 1528-1546 http://edamontology.org/data_3134 denotes gene transcription

Lectin-Jamboree

Id Subject Object Predicate Lexical cue
T1 225-231 lectin denotes lectin
T2 313-319 lectin denotes lectin

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-131 Sentence denotes Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: implication of the promoter sequence IL-5REIII.
T2 132-391 Sentence denotes Our previous work demonstrated the capacity of galectin-3 (a beta-galactoside binding animal lectin) to inhibit IL-5 gene expression in different cell types, but the interaction of lectin with the cells and the pathways for the inhibition process are unknown.
T3 392-473 Sentence denotes One of the purposes of this work was to study the cellular ligand for galectin-3.
T4 474-719 Sentence denotes We have demonstrated that galectin-3 can bind to the low affinity IgG receptor (FcgammaRII or CD32) by using different experimental approaches, such as flow cytometry, fusion protein GST technology, and with a model of FcgammaRII-deficient mice.
T5 720-873 Sentence denotes To further analyze the interaction between FcgammaRII and galectin-3, and its implication in IL-5 gene down-regulation we used FcgammaRII-deficient mice.
T6 874-978 Sentence denotes When PBMC from these mice were incubated with galectin-3, the expression of the IL-5 gene was unchanged.
T7 979-1121 Sentence denotes However, when PBMC from wild type mice and FcgammaRIII-deficient mice were incubated with galectin-3, IL-5 gene expression was down-regulated.
T8 1122-1220 Sentence denotes Finally, we studied the implication of the negative regulatory sequence in the IL-5 gene promoter.
T9 1221-1311 Sentence denotes In the presence of galectin-3, a DNA-protein complex was formed with the IL-5REIII region.
T10 1312-1382 Sentence denotes This complex was not observed when unrelated oligonucleotide was used.
T11 1383-1480 Sentence denotes So, galectin-3 induces a pathway, which activates a transcription factor that binds to IL-5REIII.
T12 1481-1547 Sentence denotes This interaction is capable of inhibiting IL-5 gene transcription.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 714-718 OrganismTaxon denotes mice 10088
T2 868-872 OrganismTaxon denotes mice 10088
T3 895-899 OrganismTaxon denotes mice 10088
T4 1013-1017 OrganismTaxon denotes mice 10088
T5 1044-1048 OrganismTaxon denotes mice 10088