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PubMed:10690989 / 803-1203 JSONTXT

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PubMed_Structured_Abstracts

Id Subject Object Predicate Lexical cue
T4 0-400 RESULTS denotes The I329T mutation shifted the voltage dependence of open probability of ClC-1 channels to the right by 192 mV, and the R338Q mutation shifted it to the right by 38 mV. In addition, the I329T ClC-1 channels deactivated to a lesser extent than normal at negative potentials. The V165G, F167L, and F413C ClC-1 channels also shifted the voltage dependence of open probability, but only by +14 to +20 mV.