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PubMed:10661407 JSONTXT

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LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
323 0-8 GeneOrGeneProduct denotes Langerin NCBIGene:50489
324 18-31 GeneOrGeneProduct denotes C-type lectin NCBIGene:50489
325 156-185 GeneOrGeneProduct denotes type II Ca2+-dependent lectin NCBIGene:50489
326 197-204 ChemicalEntity denotes mannose MESH:D008358
327 284-292 GeneOrGeneProduct denotes Langerin NCBIGene:50489
328 447-455 GeneOrGeneProduct denotes Langerin NCBIGene:50489
329 514-522 GeneOrGeneProduct denotes Langerin NCBIGene:50489
330 590-598 GeneOrGeneProduct denotes Langerin NCBIGene:50489
331 699-707 GeneOrGeneProduct denotes Langerin NCBIGene:50489
332 890-898 GeneOrGeneProduct denotes Langerin NCBIGene:50489

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-134 Sentence denotes Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.
T2 135-293 Sentence denotes We have identified a type II Ca2+-dependent lectin displaying mannose-binding specificity, exclusively expressed by Langerhans cells (LC), and named Langerin.
T3 294-421 Sentence denotes LC are uniquely characterized by Birbeck granules (BG), which are organelles consisting of superimposed and zippered membranes.
T4 422-561 Sentence denotes Here, we have shown that Langerin is constitutively associated with BG and that antibody to Langerin is internalized into these structures.
T5 562-698 Sentence denotes Remarkably, transfection of Langerin cDNA into fibroblasts created a compact network of membrane structures with typical features of BG.
T6 699-799 Sentence denotes Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
T7 800-1005 Sentence denotes Our data suggest that induction of BG is a consequence of the antigen-capture function of Langerin, allowing routing into these organelles and providing access to a nonclassical antigen-processing pathway.

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 0-8 GeneOrGeneProduct denotes Langerin
T2 12-17 GeneOrGeneProduct denotes novel
T3 18-31 GeneOrGeneProduct denotes C-type lectin
T4 68-86 GeneOrGeneProduct denotes endocytic receptor
T5 156-163 GeneOrGeneProduct denotes type II
T6 179-185 GeneOrGeneProduct denotes lectin
T7 205-212 GeneOrGeneProduct denotes binding
T8 284-292 GeneOrGeneProduct denotes Langerin
T9 447-455 GeneOrGeneProduct denotes Langerin
T10 514-522 GeneOrGeneProduct denotes Langerin
T11 590-598 GeneOrGeneProduct denotes Langerin
T12 599-603 GeneOrGeneProduct denotes cDNA
T13 631-638 GeneOrGeneProduct denotes compact
T14 699-707 GeneOrGeneProduct denotes Langerin
T15 862-869 GeneOrGeneProduct denotes antigen
T16 890-898 GeneOrGeneProduct denotes Langerin
T17 978-985 GeneOrGeneProduct denotes antigen
T18 986-996 GeneOrGeneProduct denotes processing

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-8 GeneOrGeneProduct denotes Langerin
T2 12-17 GeneOrGeneProduct denotes novel
T3 18-31 GeneOrGeneProduct denotes C-type lectin
T4 55-60 GeneOrGeneProduct denotes cells
T5 68-86 GeneOrGeneProduct denotes endocytic receptor
T6 92-99 GeneOrGeneProduct denotes induces
T7 104-113 GeneOrGeneProduct denotes formation
T8 156-163 GeneOrGeneProduct denotes type II
T9 164-167 GeneOrGeneProduct denotes Ca2
T10 179-185 GeneOrGeneProduct denotes lectin
T11 205-212 GeneOrGeneProduct denotes binding
T12 262-267 GeneOrGeneProduct denotes cells
T13 284-292 GeneOrGeneProduct denotes Langerin
T14 402-410 GeneOrGeneProduct denotes zippered
T15 447-455 GeneOrGeneProduct denotes Langerin
T16 514-522 GeneOrGeneProduct denotes Langerin
T17 590-598 GeneOrGeneProduct denotes Langerin
T18 599-603 GeneOrGeneProduct denotes cDNA
T19 621-628 GeneOrGeneProduct denotes created
T20 631-638 GeneOrGeneProduct denotes compact
T21 699-707 GeneOrGeneProduct denotes Langerin
T22 725-732 GeneOrGeneProduct denotes inducer
T23 765-774 GeneOrGeneProduct denotes zippering
T24 789-798 GeneOrGeneProduct denotes formation
T25 862-869 GeneOrGeneProduct denotes antigen
T26 890-898 GeneOrGeneProduct denotes Langerin
T27 978-985 GeneOrGeneProduct denotes antigen
T28 986-996 GeneOrGeneProduct denotes processing

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 0-8 GeneOrGeneProduct denotes Langerin
T2 18-31 GeneOrGeneProduct denotes C-type lectin
T3 68-86 GeneOrGeneProduct denotes endocytic receptor
T4 179-185 GeneOrGeneProduct denotes lectin
T5 284-292 GeneOrGeneProduct denotes Langerin
T6 447-455 GeneOrGeneProduct denotes Langerin
T7 514-522 GeneOrGeneProduct denotes Langerin
T8 590-598 GeneOrGeneProduct denotes Langerin
T9 631-638 GeneOrGeneProduct denotes compact
T10 699-707 GeneOrGeneProduct denotes Langerin
T11 890-898 GeneOrGeneProduct denotes Langerin

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 269-271 DiseaseOrPhenotypicFeature denotes LC 0016060
T2 294-296 DiseaseOrPhenotypicFeature denotes LC 0016060

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 197-204 ChemicalEntity denotes mannose D008358|http://purl.obolibrary.org/obo/CHEBI_37684

LitCoin-training-merged

Id Subject Object Predicate Lexical cue ID:
T1 197-204 ChemicalEntity denotes mannose http://purl.obolibrary.org/obo/CHEBI_37684|D008358
T11 890-898 GeneOrGeneProduct denotes Langerin
T10 699-707 GeneOrGeneProduct denotes Langerin
T9 631-638 GeneOrGeneProduct denotes compact
T8 590-598 GeneOrGeneProduct denotes Langerin
T7 514-522 GeneOrGeneProduct denotes Langerin
T6 447-455 GeneOrGeneProduct denotes Langerin
T5 284-292 GeneOrGeneProduct denotes Langerin
T4 179-185 GeneOrGeneProduct denotes lectin
T3 68-86 GeneOrGeneProduct denotes endocytic receptor
T2 18-31 GeneOrGeneProduct denotes C-type lectin
T10729 0-8 GeneOrGeneProduct denotes Langerin

Lectin_function

Id Subject Object Predicate Lexical cue
T1 0-8 GX_000014 denotes Langerin
T2 18-31 GL_000114 denotes C-type lectin
T3 18-31 GL_000115 denotes C-type lectin
T4 25-31 GX_000027 denotes lectin
T5 25-31 GX_000045 denotes lectin
T6 179-185 GX_000027 denotes lectin
T7 179-185 GX_000045 denotes lectin
T8 284-292 GX_000014 denotes Langerin
T9 447-455 GX_000014 denotes Langerin
T10 514-522 GX_000014 denotes Langerin
T11 590-598 GX_000014 denotes Langerin
T12 699-707 GX_000014 denotes Langerin
T13 890-898 GX_000014 denotes Langerin