| Id |
Subject |
Object |
Predicate |
Lexical cue |
| BEL:20000116 |
508-632 |
a(CHEBI:androgen) directlyIncreases complex(p(HGNC:AR),p(HGNC:PIAS1)) |
denotes |
Binding of PIAS1 to human AR DNA+ligand binding domains was androgen dependent in the yeast liquid beta-galactosidase assay. |
| BEL:20000118 |
736-839 |
a(CHEBI:androgen) directlyIncreases complex(p(HGNC:AR),p(HGNC:PIAS1)) |
denotes |
PIAS1 binding to full-length human AR in a reversed yeast two hybrid system was also androgen dependent |
| BEL:20000116 |
508-631 |
a(CHEBI:androgen) directlyIncreases complex(p(HGNC:AR),p(HGNC:PIAS1)) |
denotes |
Binding of PIAS1 to human AR DNA+ligand binding domains was androgen dependent in the yeast liquid beta-galactosidase assay |
| BEL:20000118 |
736-839 |
a(CHEBI:androgen) directlyIncreases complex(p(HGNC:AR),p(HGNC:PIAS1)) |
denotes |
PIAS1 binding to full-length human AR in a reversed yeast two hybrid system was also androgen dependent |
| BEL:20023478 |
508-839 |
a(CHEBI:androgen) directlyIncreases complex(p(HGNC:AR),p(HGNC:PIAS1)) |
denotes |
Binding of PIAS1 to human AR DNA+ligand binding domains was androgen dependent in the yeast liquid beta-galactosidase assay. Activation of binding by dihydrotestosterone was greater than testosterone > estradiol > progesterone. PIAS1 binding to full-length human AR in a reversed yeast two hybrid system was also androgen dependent |
| BEL:20044378 |
973-1286 |
p(HGNC:PIAS1) increases tscript(p(HGNC:AR)) |
denotes |
In transient cotransfection assays using CV1 cells with full-length human AR and a mouse mammary tumor virus luciferase reporter vector, there was an androgen-dependent 3- to 5-fold greater increase in luciferase activity with PIAS1 over that obtained with an equal amount of control antisense cDNA or mutant PIAS |
