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sentences

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes Structural and functional definition of the human chitinase chitin-binding domain.
T2 83-275 Sentence denotes Mammalian chitinase, a chitinolytic enzyme expressed by macrophages, has been detected in atherosclerotic plaques and is elevated in blood and tissues of guinea pigs infected with Aspergillus.
T3 276-321 Sentence denotes Its normal physiological function is unknown.
T4 322-429 Sentence denotes To understand how the enzyme interacts with its substrate, we have characterized the chitin-binding domain.
T5 430-526 Sentence denotes The C-terminal 49 amino acids make up the minimal sequence required for chitin binding activity.
T6 527-699 Sentence denotes The absence of this domain does not affect the ability of the enzyme to hydrolyze the soluble substrate, triacetylchitotriose, but abolishes hydrolysis of insoluble chitin.
T7 700-851 Sentence denotes Within the minimal chitin-binding domain are six cysteines; mutation of any one of these to serine results in complete loss of chitin binding activity.
T8 852-957 Sentence denotes Analysis of purified recombinant chitin-binding domain revealed the presence of three disulfide linkages.
T9 958-1105 Sentence denotes The recombinant domain binds specifically to chitin but does not bind chitosan, cellulose, xylan, beta-1, 3-glucan, beta-1,3-1,4-glucan, or mannan.
T10 1106-1280 Sentence denotes Fluorescently tagged chitin-binding domain was used to demonstrate chitin-specific binding to Saccharomyces cerevisiae, Candida albicans, Mucor rouxii, and Neurospora crassa.
T11 1281-1518 Sentence denotes These experiments define structural features of the minimal domain of human chitinase required for both specifically binding to and hydrolyzing insoluble chitin and demonstrate relevant binding within the context of the fungal cell wall.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 216-221 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T2 216-221 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 216-221 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 60-66 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T2 407-413 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T3 502-508 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T4 692-698 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T5 719-725 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T6 827-833 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T7 885-891 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T8 1003-1009 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T9 1127-1133 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T10 1173-1179 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T11 1435-1441 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 44-49 OrganismTaxon denotes human 9606
T2 237-248 OrganismTaxon denotes guinea pigs 10140
T3 263-274 OrganismTaxon denotes Aspergillus 5052
T4 1200-1224 OrganismTaxon denotes Saccharomyces cerevisiae 4932
T5 1226-1242 OrganismTaxon denotes Candida albicans 5476
T6 1244-1256 OrganismTaxon denotes Mucor rouxii 29923
T7 1262-1279 OrganismTaxon denotes Neurospora crassa 5141
T8 1351-1356 OrganismTaxon denotes human 9606

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 139-150 Cell denotes macrophages http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T3 1501-1512 Cell denotes fungal cell http://purl.obolibrary.org/obo/CL:0000521

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 139-150 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T2 216-221 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 1501-1512 Body_part denotes fungal cell http://purl.obolibrary.org/obo/CL_0000521
T4 1513-1517 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 216-221 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315

sentences

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes Structural and functional definition of the human chitinase chitin-binding domain.
T2 83-275 Sentence denotes Mammalian chitinase, a chitinolytic enzyme expressed by macrophages, has been detected in atherosclerotic plaques and is elevated in blood and tissues of guinea pigs infected with Aspergillus.
T3 276-321 Sentence denotes Its normal physiological function is unknown.
T4 322-429 Sentence denotes To understand how the enzyme interacts with its substrate, we have characterized the chitin-binding domain.
T5 430-526 Sentence denotes The C-terminal 49 amino acids make up the minimal sequence required for chitin binding activity.
T6 527-699 Sentence denotes The absence of this domain does not affect the ability of the enzyme to hydrolyze the soluble substrate, triacetylchitotriose, but abolishes hydrolysis of insoluble chitin.
T7 700-851 Sentence denotes Within the minimal chitin-binding domain are six cysteines; mutation of any one of these to serine results in complete loss of chitin binding activity.
T8 852-957 Sentence denotes Analysis of purified recombinant chitin-binding domain revealed the presence of three disulfide linkages.
T9 958-1105 Sentence denotes The recombinant domain binds specifically to chitin but does not bind chitosan, cellulose, xylan, beta-1, 3-glucan, beta-1,3-1,4-glucan, or mannan.
T10 1106-1280 Sentence denotes Fluorescently tagged chitin-binding domain was used to demonstrate chitin-specific binding to Saccharomyces cerevisiae, Candida albicans, Mucor rouxii, and Neurospora crassa.
T11 1281-1518 Sentence denotes These experiments define structural features of the minimal domain of human chitinase required for both specifically binding to and hydrolyzing insoluble chitin and demonstrate relevant binding within the context of the fungal cell wall.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes Structural and functional definition of the human chitinase chitin-binding domain.
T2 83-321 Sentence denotes Mammalian chitinase, a chitinolytic enzyme expressed by macrophages, has been detected in atherosclerotic plaques and is elevated in blood and tissues of guinea pigs infected with Aspergillus. Its normal physiological function is unknown.
T3 322-429 Sentence denotes To understand how the enzyme interacts with its substrate, we have characterized the chitin-binding domain.
T4 430-526 Sentence denotes The C-terminal 49 amino acids make up the minimal sequence required for chitin binding activity.
T5 527-699 Sentence denotes The absence of this domain does not affect the ability of the enzyme to hydrolyze the soluble substrate, triacetylchitotriose, but abolishes hydrolysis of insoluble chitin.
T6 700-851 Sentence denotes Within the minimal chitin-binding domain are six cysteines; mutation of any one of these to serine results in complete loss of chitin binding activity.
T7 852-957 Sentence denotes Analysis of purified recombinant chitin-binding domain revealed the presence of three disulfide linkages.
T8 958-1105 Sentence denotes The recombinant domain binds specifically to chitin but does not bind chitosan, cellulose, xylan, beta-1, 3-glucan, beta-1,3-1,4-glucan, or mannan.
T9 1106-1280 Sentence denotes Fluorescently tagged chitin-binding domain was used to demonstrate chitin-specific binding to Saccharomyces cerevisiae, Candida albicans, Mucor rouxii, and Neurospora crassa.
T10 1281-1518 Sentence denotes These experiments define structural features of the minimal domain of human chitinase required for both specifically binding to and hydrolyzing insoluble chitin and demonstrate relevant binding within the context of the fungal cell wall.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 60-66 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T2 407-413 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T3 502-508 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T4 692-698 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T5 719-725 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T6 827-833 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T7 885-891 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T8 1003-1009 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T9 1127-1133 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T10 1173-1179 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY
T11 1435-1441 Glycan denotes chitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G97099AY

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 44-49 OrganismTaxon denotes human 9606
T2 237-248 OrganismTaxon denotes guinea pigs 10140
T3 263-274 OrganismTaxon denotes Aspergillus 5052
T4 1200-1224 OrganismTaxon denotes Saccharomyces cerevisiae 4932
T5 1226-1242 OrganismTaxon denotes Candida albicans 5476
T6 1244-1256 OrganismTaxon denotes Mucor rouxii 29923
T7 1262-1279 OrganismTaxon denotes Neurospora crassa 5141
T8 1351-1356 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 139-150 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T2 216-221 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 1501-1512 Body_part denotes fungal cell http://purl.obolibrary.org/obo/CL_0000521
T4 1513-1517 Body_part denotes wall http://purl.obolibrary.org/obo/UBERON_0000060

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 139-150 Cell denotes macrophages http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T3 1501-1512 Cell denotes fungal cell http://purl.obolibrary.org/obo/CL:0000521