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PubMed:10574991 JSONTXT

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ggdb-test

Id Subject Object Predicate Lexical cue
T1 425-460 https://acgg.asia/db/ggdb/info/gg224 denotes phosphatidylinositol glycan-class N
T2 1400-1404 https://acgg.asia/db/ggdb/info/gg224 denotes MCD4

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 106-113 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T2 681-688 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T3 834-841 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T4 983-990 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T5 1187-1194 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ

GGDB-2020

Id Subject Object Predicate Lexical cue
T1 425-460 https://acgg.asia/db/ggdb/info/gg224 denotes phosphatidylinositol glycan-class N
T2 1400-1404 https://acgg.asia/db/ggdb/info/gg224 denotes MCD4

sentences

Id Subject Object Predicate Lexical cue
T1 0-150 Sentence denotes Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol.
T2 151-308 Sentence denotes Many cell surface proteins are anchored to the membrane via a glycosylphosphatidylinositol (GPI) moiety, which is attached to the C terminus of the proteins.
T3 309-406 Sentence denotes The core of the GPI anchor is conserved in all eukaryotes but is modified by various side chains.
T4 407-586 Sentence denotes We cloned a mouse phosphatidylinositol glycan-class N (Pig-n) gene that encodes a 931amino acid protein expressed in the endoplasmic reticulum, which is homologous to yeast Mcd4p.
T5 587-641 Sentence denotes We disrupted the gene in F9 embryonal carcinoma cells.
T6 642-751 Sentence denotes In the Pig-n knockout cells, the first mannose in the GPI precursors was not modified by phosphoethanolamine.
T7 752-879 Sentence denotes Nevertheless, further biosynthetic steps continued with the addition of the third mannose and the terminal phosphoethanolamine.
T8 880-1080 Sentence denotes The surface expression of Thy-1 was only partially affected, indicating that modification of the first mannose by phosphoethanolamine is not essential for attachment of GPI anchors in mammalian cells.
T9 1081-1289 Sentence denotes An inhibitor of GPI biosynthesis, YW3548/BE49385A, inhibited transfer of phosphoethanolamine to the first mannose in mammalian cells but only slightly affected the surface expression of GPI-anchored proteins.
T10 1290-1503 Sentence denotes Biosynthesis of GPI in the Pig-n knockout cells was not affected by YW3548/BE49385A, and yeast overexpressing MCD4 was highly resistant to YW3548/BE49385A, suggesting that Pig-n and Mcd4p are targets of this drug.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 106-113 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T2 681-688 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T3 834-841 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T4 983-990 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T5 1187-1194 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

bionlp-st-pc-2013-training

Id Subject Object Predicate Lexical cue
T1 0-5 Gene_or_gene_product denotes Pig-n
T2 38-43 Gene_or_gene_product denotes Mcd4p
T3 73-92 Simple_chemical denotes phosphoethanolamine
T4 106-113 Simple_chemical denotes mannose
T5 121-149 Simple_chemical denotes glycosylphosphatidylinositol
T6 156-168 Cellular_component denotes cell surface
T7 198-206 Cellular_component denotes membrane
T8 213-241 Simple_chemical denotes glycosylphosphatidylinositol
T9 243-246 Simple_chemical denotes GPI
T10 325-335 Simple_chemical denotes GPI anchor
T11 425-460 Gene_or_gene_product denotes phosphatidylinositol glycan-class N
T12 462-467 Gene_or_gene_product denotes Pig-n
T13 528-549 Cellular_component denotes endoplasmic reticulum
T14 580-585 Gene_or_gene_product denotes Mcd4p
T15 649-654 Gene_or_gene_product denotes Pig-n
T16 681-688 Simple_chemical denotes mannose
T17 696-699 Simple_chemical denotes GPI
T18 731-750 Simple_chemical denotes phosphoethanolamine
T19 834-841 Simple_chemical denotes mannose
T20 859-878 Simple_chemical denotes phosphoethanolamine
T21 884-891 Cellular_component denotes surface
T22 906-911 Gene_or_gene_product denotes Thy-1
T23 983-990 Simple_chemical denotes mannose
T24 994-1013 Simple_chemical denotes phosphoethanolamine
T25 1049-1060 Simple_chemical denotes GPI anchors
T26 1097-1100 Simple_chemical denotes GPI
T27 1115-1121 Simple_chemical denotes YW3548
T28 1122-1130 Simple_chemical denotes BE49385A
T29 1154-1173 Simple_chemical denotes phosphoethanolamine
T30 1187-1194 Simple_chemical denotes mannose
T31 1245-1252 Cellular_component denotes surface
T32 1267-1270 Simple_chemical denotes GPI
T33 1306-1309 Simple_chemical denotes GPI
T34 1317-1322 Gene_or_gene_product denotes Pig-n
T35 1358-1364 Simple_chemical denotes YW3548
T36 1365-1373 Simple_chemical denotes BE49385A
T37 1400-1404 Gene_or_gene_product denotes MCD4
T38 1429-1435 Simple_chemical denotes YW3548
T39 1436-1444 Simple_chemical denotes BE49385A
T40 1462-1467 Gene_or_gene_product denotes Pig-n
T41 1472-1477 Gene_or_gene_product denotes Mcd4p

glycogenes

Id Subject Object Predicate Lexical cue
PD-GlycoGenes20190927-B_T1 0-5 https://acgg.asia/db/ggdb/info/gg224 denotes Pig-n
PD-GlycoGenes20190927-B_T2 462-467 https://acgg.asia/db/ggdb/info/gg224 denotes Pig-n
PD-GlycoGenes20190927-B_T3 649-654 https://acgg.asia/db/ggdb/info/gg224 denotes Pig-n
PD-GlycoGenes20190927-B_T4 1317-1322 https://acgg.asia/db/ggdb/info/gg224 denotes Pig-n
PD-GlycoGenes20190927-B_T5 1462-1467 https://acgg.asia/db/ggdb/info/gg224 denotes Pig-n

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 615-634 Disease denotes embryonal carcinoma http://purl.obolibrary.org/obo/MONDO_0005440

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 356-366 OrganismTaxon denotes eukaryotes 2759
T2 419-424 OrganismTaxon denotes mouse 10088|10090

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 198-206 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T4 540-549 Body_part denotes reticulum http://purl.obolibrary.org/obo/UBERON_0007361

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 625-634 Phenotype denotes carcinoma HP:0030731