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PubMed:10570222 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 22-31 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T2 22-31 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T3 22-31 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T4 192-201 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T5 192-201 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T6 192-201 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T7 203-221 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactosylceramide
T8 365-374 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T9 365-374 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T10 365-374 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T11 446-453 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose
T12 612-621 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T13 612-621 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T14 612-621 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T15 677-686 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T16 677-686 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T17 677-686 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T18 847-854 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose
T19 925-934 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T20 925-934 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T21 925-934 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T22 1067-1076 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T23 1067-1076 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T24 1067-1076 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T25 1325-1334 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T26 1325-1334 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T27 1325-1334 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T28 1403-1412 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T29 1403-1412 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T30 1403-1412 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T31 1519-1528 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T32 1519-1528 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T33 1519-1528 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T34 1674-1683 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T35 1674-1683 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T36 1674-1683 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 22-31 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T4 192-201 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T7 203-221 Glycan_Motif denotes galactosylceramide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE
T8 365-374 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T11 446-453 Glycan_Motif denotes glucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG
T12 612-621 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T15 677-686 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T18 847-854 Glycan_Motif denotes glucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG
T19 925-934 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T22 1067-1076 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T25 1325-1334 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T28 1403-1412 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T31 1519-1528 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY
T34 1674-1683 Glycan_Motif denotes sulfatide https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G95090DW|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G72548RZ|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G40843KY

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 22-31 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T2 22-31 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T3 22-31 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T4 192-201 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T5 192-201 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T6 192-201 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T7 203-221 https://glytoucan.org/Structures/Glycans/G65889KE denotes galactosylceramide
T8 365-374 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T9 365-374 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T10 365-374 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T11 446-453 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose
T12 612-621 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T13 612-621 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T14 612-621 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T15 677-686 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T16 677-686 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T17 677-686 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T18 847-854 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose
T19 925-934 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T20 925-934 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T21 925-934 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T22 1067-1076 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T23 1067-1076 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T24 1067-1076 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T25 1325-1334 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T26 1325-1334 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T27 1325-1334 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T28 1403-1412 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T29 1403-1412 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T30 1403-1412 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T31 1519-1528 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T32 1519-1528 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T33 1519-1528 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide
T34 1674-1683 https://glytoucan.org/Structures/Glycans/G40843KY denotes sulfatide
T35 1674-1683 https://glytoucan.org/Structures/Glycans/G72548RZ denotes sulfatide
T36 1674-1683 https://glytoucan.org/Structures/Glycans/G95090DW denotes sulfatide

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 203-221 http://www.glycoepitope.jp/epitopes/EP0074 denotes galactosylceramide

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 39-59 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T2 67-75 http://purl.obolibrary.org/obo/MAT_0000075 denotes pancreas
T3 312-332 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T4 703-723 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T5 1312-1317 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T6 1743-1763 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T7 1771-1779 http://purl.obolibrary.org/obo/MAT_0000075 denotes pancreas

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 4-21 FMAID:82815 denotes glycosphingolipid
_T2 4-21 FMAID:196810 denotes glycosphingolipid
_T3 4-21 FMAID:196807 denotes glycosphingolipid
_T4 4-21 FMAID:196814 denotes glycosphingolipid
_T5 4-21 FMAID:196812 denotes glycosphingolipid
_T6 4-21 FMAID:82813 denotes glycosphingolipid
_T7 4-21 FMAID:196808 denotes glycosphingolipid
_T8 4-21 FMAID:82817 denotes glycosphingolipid
_T9 4-21 FMAID:82814 denotes glycosphingolipid
_T10 4-21 FMAID:196809 denotes glycosphingolipid
_T11 4-21 FMAID:82812 denotes glycosphingolipid
_T12 4-21 FMAID:82818 denotes glycosphingolipid
_T13 4-21 FMAID:196813 denotes glycosphingolipid
_T14 4-21 FMAID:196806 denotes glycosphingolipid
_T15 4-21 FMAID:82811 denotes glycosphingolipid
_T16 4-21 FMAID:82819 denotes glycosphingolipid
_T17 4-31 FMAID:196815 denotes glycosphingolipid sulfatide
_T18 39-59 FMAID:106464 denotes islets of Langerhans
_T19 39-59 FMAID:183641 denotes islets of Langerhans
_T20 67-75 FMAID:93673 denotes pancreas
_T21 67-75 FMAID:7198 denotes pancreas
_T22 132-139 FMAID:83365 denotes insulin
_T23 132-139 FMAID:197650 denotes insulin
_T24 203-221 FMAID:82821 denotes galactosylceramide
_T25 203-221 FMAID:196817 denotes galactosylceramide
_T26 274-281 FMAID:197650 denotes insulin
_T27 274-281 FMAID:83365 denotes insulin
_T28 292-297 FMAID:68646 denotes cells
_T29 292-297 FMAID:169002 denotes cells
_T30 312-332 FMAID:106464 denotes islets of Langerhans
_T31 312-332 FMAID:183641 denotes islets of Langerhans
_T32 446-453 FMAID:82743 denotes glucose
_T33 446-453 FMAID:196732 denotes glucose
_T34 499-516 FMAID:82817 denotes glycosphingolipid
_T35 499-516 FMAID:82815 denotes glycosphingolipid
_T36 499-516 FMAID:196812 denotes glycosphingolipid
_T37 499-516 FMAID:82813 denotes glycosphingolipid
_T38 499-516 FMAID:82814 denotes glycosphingolipid
_T39 499-516 FMAID:196809 denotes glycosphingolipid
_T40 499-516 FMAID:82818 denotes glycosphingolipid
_T41 499-516 FMAID:196813 denotes glycosphingolipid
_T42 499-516 FMAID:82819 denotes glycosphingolipid
_T43 499-516 FMAID:196814 denotes glycosphingolipid
_T44 499-516 FMAID:82811 denotes glycosphingolipid
_T45 499-516 FMAID:196806 denotes glycosphingolipid
_T46 499-516 FMAID:196815 denotes glycosphingolipid
_T47 499-516 FMAID:196807 denotes glycosphingolipid
_T48 499-516 FMAID:82812 denotes glycosphingolipid
_T49 499-516 FMAID:196810 denotes glycosphingolipid
_T50 499-516 FMAID:196808 denotes glycosphingolipid
_T51 569-571 FMAID:168188 denotes B1
_T52 703-723 FMAID:183641 denotes islets of Langerhans
_T53 703-723 FMAID:106464 denotes islets of Langerhans
_T54 733-737 FMAID:214734 denotes main
_T55 819-827 FMAID:63836 denotes lysosome
_T56 819-827 FMAID:162299 denotes lysosome
_T57 847-854 FMAID:196732 denotes glucose
_T58 847-854 FMAID:82743 denotes glucose
_T59 988-997 FMAID:196789 denotes galactose
_T60 988-997 FMAID:82794 denotes galactose
_T61 988-1006 FMAID:82821 denotes galactose:ceramide
_T62 988-1006 FMAID:196817 denotes galactose:ceramide
_T63 1160-1171 FMAID:82738 denotes fatty acids
_T64 1160-1171 FMAID:196726 denotes fatty acids
_T65 1312-1317 FMAID:146514 denotes brain
_T66 1312-1317 FMAID:50801 denotes brain
_T67 1420-1438 FMAID:199022 denotes secretory granules
_T68 1420-1438 FMAID:84758 denotes secretory granules
_T69 1444-1457 FMAID:67108 denotes Golgi network
_T70 1444-1457 FMAID:67113 denotes Golgi network
_T71 1444-1457 FMAID:165053 denotes Golgi network
_T72 1444-1457 FMAID:165051 denotes Golgi network
_T73 1450-1457 FMAID:179365 denotes network
_T74 1466-1475 FMAID:162299 denotes lysosomes
_T75 1466-1475 FMAID:63836 denotes lysosomes
_T76 1569-1576 FMAID:83365 denotes insulin
_T77 1569-1576 FMAID:197650 denotes insulin
_T78 1728-1735 FMAID:83365 denotes insulin
_T79 1728-1735 FMAID:197650 denotes insulin
_T80 1743-1763 FMAID:183641 denotes islets of Langerhans
_T81 1743-1763 FMAID:106464 denotes islets of Langerhans
_T82 1771-1779 FMAID:93673 denotes pancreas
_T83 1771-1779 FMAID:7198 denotes pancreas

uniprot-human

Id Subject Object Predicate Lexical cue
T1 132-139 http://www.uniprot.org/uniprot/P01308 denotes insulin
T2 274-281 http://www.uniprot.org/uniprot/P01308 denotes insulin
T3 1569-1576 http://www.uniprot.org/uniprot/P01308 denotes insulin
T4 1728-1735 http://www.uniprot.org/uniprot/P01308 denotes insulin

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 1007-1028 http://www.uniprot.org/uniprot/P23336 denotes galactosyltransferase

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 292-297 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T2 1343-1351 http://purl.bioontology.org/ontology/NCBITAXON/68518 denotes electron

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-152 Sentence denotes The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
TextSentencer_T2 153-333 Sentence denotes In previous studies we have shown that sulfatide (galactosylceramide-3-O-sulfate), in various species, is present in the insulin-producing cells in pancreatic islets of Langerhans.
TextSentencer_T3 334-651 Sentence denotes In this study the synthesis of sulfatide in the islets has been investigated by pulse chase labeling at varying glucose levels and in the presence or absence of the glycosphingolipid synthesis inhibitory agents, Brefeldin A, fumonisin B1 and chloroquine and the distribution of sulfatide by immune-electronmicroscopy.
TextSentencer_T4 652-1077 Sentence denotes The data showed that (1) sulfatide was produced in islets of Langerhans, (2) the main pathway for synthesis was through recycling involving partial degradation in the lysosome, and that (3) high glucose levels, although not primarily reflected in an increased synthesis of sulfatide, lead to an increased expression of mRNA for the UDP-galactose:ceramide galactosyltransferase, producing the immediate precursor of sulfatide.
TextSentencer_T5 1078-1335 Sentence denotes Furthermore, mass spectrometry analyses revealed a high proportion of short chain fatty acids, C16:0 (50%) and no hydroxylated forms and thus special physicochemical properties, indicating important differences between pancreatic and brain/neural sulfatide.
TextSentencer_T6 1336-1490 Sentence denotes Immune electron microscopy revealed an intracellular expression of sulfatide in the secretory granules, the Golgi network and the lysosomes of the islets.
TextSentencer_T7 1491-1638 Sentence denotes These results indicate that sulfatide follows the same intracellular route as insulin and suggest a functional association between these molecules.
TextSentencer_T8 1639-1780 Sentence denotes We have raised the hypothesis that sulfatide possibly plays a role in the trafficking of insulin in the islets of Langerhans in rat pancreas.
T1 0-152 Sentence denotes The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
T2 153-651 Sentence denotes In previous studies we have shown that sulfatide (galactosylceramide-3-O-sulfate), in various species, is present in the insulin-producing cells in pancreatic islets of Langerhans. In this study the synthesis of sulfatide in the islets has been investigated by pulse chase labeling at varying glucose levels and in the presence or absence of the glycosphingolipid synthesis inhibitory agents, Brefeldin A, fumonisin B1 and chloroquine and the distribution of sulfatide by immune-electronmicroscopy.
T3 652-1077 Sentence denotes The data showed that (1) sulfatide was produced in islets of Langerhans, (2) the main pathway for synthesis was through recycling involving partial degradation in the lysosome, and that (3) high glucose levels, although not primarily reflected in an increased synthesis of sulfatide, lead to an increased expression of mRNA for the UDP-galactose:ceramide galactosyltransferase, producing the immediate precursor of sulfatide.
T4 1078-1335 Sentence denotes Furthermore, mass spectrometry analyses revealed a high proportion of short chain fatty acids, C16:0 (50%) and no hydroxylated forms and thus special physicochemical properties, indicating important differences between pancreatic and brain/neural sulfatide.
T5 1336-1490 Sentence denotes Immune electron microscopy revealed an intracellular expression of sulfatide in the secretory granules, the Golgi network and the lysosomes of the islets.
T6 1491-1638 Sentence denotes These results indicate that sulfatide follows the same intracellular route as insulin and suggest a functional association between these molecules.
T7 1639-1780 Sentence denotes We have raised the hypothesis that sulfatide possibly plays a role in the trafficking of insulin in the islets of Langerhans in rat pancreas.
T1 0-152 Sentence denotes The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
T2 153-333 Sentence denotes In previous studies we have shown that sulfatide (galactosylceramide-3-O-sulfate), in various species, is present in the insulin-producing cells in pancreatic islets of Langerhans.
T3 334-651 Sentence denotes In this study the synthesis of sulfatide in the islets has been investigated by pulse chase labeling at varying glucose levels and in the presence or absence of the glycosphingolipid synthesis inhibitory agents, Brefeldin A, fumonisin B1 and chloroquine and the distribution of sulfatide by immune-electronmicroscopy.
T4 652-1077 Sentence denotes The data showed that (1) sulfatide was produced in islets of Langerhans, (2) the main pathway for synthesis was through recycling involving partial degradation in the lysosome, and that (3) high glucose levels, although not primarily reflected in an increased synthesis of sulfatide, lead to an increased expression of mRNA for the UDP-galactose:ceramide galactosyltransferase, producing the immediate precursor of sulfatide.
T5 1078-1335 Sentence denotes Furthermore, mass spectrometry analyses revealed a high proportion of short chain fatty acids, C16:0 (50%) and no hydroxylated forms and thus special physicochemical properties, indicating important differences between pancreatic and brain/neural sulfatide.
T6 1336-1490 Sentence denotes Immune electron microscopy revealed an intracellular expression of sulfatide in the secretory granules, the Golgi network and the lysosomes of the islets.
T7 1491-1638 Sentence denotes These results indicate that sulfatide follows the same intracellular route as insulin and suggest a functional association between these molecules.
T8 1639-1780 Sentence denotes We have raised the hypothesis that sulfatide possibly plays a role in the trafficking of insulin in the islets of Langerhans in rat pancreas.

GO-BP

Id Subject Object Predicate Lexical cue
T1 226-233 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T2 352-361 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T3 517-526 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T4 750-759 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T5 912-921 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T6 499-526 http://purl.obolibrary.org/obo/GO_0006688 denotes glycosphingolipid synthesis
T7 800-811 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation

GO-CC

Id Subject Object Predicate Lexical cue
T1 292-297 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2 819-827 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosome
T3 1466-1475 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T4 1375-1388 http://purl.obolibrary.org/obo/GO_0005622 denotes intracellular
T5 1546-1559 http://purl.obolibrary.org/obo/GO_0005622 denotes intracellular
T6 1420-1438 http://purl.obolibrary.org/obo/GO_0030141 denotes secretory granules
T7 1444-1449 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 39-59 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
T2 312-332 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
T3 703-723 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
T4 1743-1763 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
T5 67-75 http://purl.obolibrary.org/obo/UBERON_0001264 denotes pancreas
T6 1771-1779 http://purl.obolibrary.org/obo/UBERON_0001264 denotes pancreas
T7 1312-1317 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 39-59 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T2 67-75 http://purl.obolibrary.org/obo/MAT_0000075 denotes pancreas
T3 312-332 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T4 703-723 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T5 1312-1317 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T6 1743-1763 http://purl.obolibrary.org/obo/MAT_0000076 denotes islets of Langerhans
T7 1771-1779 http://purl.obolibrary.org/obo/MAT_0000075 denotes pancreas

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 1173-1176 https://acgg.asia/db/lfdb/LfDB0050 denotes C16

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 426-434 id denotes labeling
PD-GlycoEpitope-B_T2 203-221 http://www.glycoepitope.jp/epitopes/EP0074 denotes galactosylceramide

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1312-1317 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
PD-UBERON-AE-B_T2 39-59 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
PD-UBERON-AE-B_T3 312-332 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
PD-UBERON-AE-B_T4 703-723 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
PD-UBERON-AE-B_T5 1743-1763 http://purl.obolibrary.org/obo/UBERON_0000006 denotes islets of Langerhans
PD-UBERON-AE-B_T6 67-75 http://purl.obolibrary.org/obo/UBERON_0001264 denotes pancreas
PD-UBERON-AE-B_T7 1771-1779 http://purl.obolibrary.org/obo/UBERON_0001264 denotes pancreas

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 67-75 Disease denotes pancreas http://purl.obolibrary.org/obo/MONDO_0021040
T2 1771-1779 Disease denotes pancreas http://purl.obolibrary.org/obo/MONDO_0021040

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 39-59 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T2 67-75 Body_part denotes pancreas http://purl.obolibrary.org/obo/MAT_0000075
T3 312-332 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T4 703-723 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T5 1312-1317 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T6 1743-1763 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T7 1771-1779 Body_part denotes pancreas http://purl.obolibrary.org/obo/MAT_0000075

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 203-221 Glycan denotes galactosylceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 203-221 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes galactosylceramide http://www.glycoepitope.jp/epitopes/EP0074

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 39-59 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T2 67-75 Body_part denotes pancreas http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040
T4 312-332 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T5 703-723 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T6 819-827 Body_part denotes lysosome http://purl.obolibrary.org/obo/GO_0005764
T7 1312-1317 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T9 1375-1388 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T10 1420-1438 Body_part denotes secretory granules http://purl.obolibrary.org/obo/GO_0030141
T11 1444-1449 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T12 1466-1475 Body_part denotes lysosomes http://purl.obolibrary.org/obo/GO_0005764
T13 1546-1559 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T14 1743-1763 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T15 1771-1779 Body_part denotes pancreas http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-152 Sentence denotes The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
TextSentencer_T2 153-333 Sentence denotes In previous studies we have shown that sulfatide (galactosylceramide-3-O-sulfate), in various species, is present in the insulin-producing cells in pancreatic islets of Langerhans.
TextSentencer_T3 334-651 Sentence denotes In this study the synthesis of sulfatide in the islets has been investigated by pulse chase labeling at varying glucose levels and in the presence or absence of the glycosphingolipid synthesis inhibitory agents, Brefeldin A, fumonisin B1 and chloroquine and the distribution of sulfatide by immune-electronmicroscopy.
TextSentencer_T4 652-1077 Sentence denotes The data showed that (1) sulfatide was produced in islets of Langerhans, (2) the main pathway for synthesis was through recycling involving partial degradation in the lysosome, and that (3) high glucose levels, although not primarily reflected in an increased synthesis of sulfatide, lead to an increased expression of mRNA for the UDP-galactose:ceramide galactosyltransferase, producing the immediate precursor of sulfatide.
TextSentencer_T5 1078-1335 Sentence denotes Furthermore, mass spectrometry analyses revealed a high proportion of short chain fatty acids, C16:0 (50%) and no hydroxylated forms and thus special physicochemical properties, indicating important differences between pancreatic and brain/neural sulfatide.
TextSentencer_T6 1336-1490 Sentence denotes Immune electron microscopy revealed an intracellular expression of sulfatide in the secretory granules, the Golgi network and the lysosomes of the islets.
TextSentencer_T7 1491-1638 Sentence denotes These results indicate that sulfatide follows the same intracellular route as insulin and suggest a functional association between these molecules.
TextSentencer_T8 1639-1780 Sentence denotes We have raised the hypothesis that sulfatide possibly plays a role in the trafficking of insulin in the islets of Langerhans in rat pancreas.
T1 0-152 Sentence denotes The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
T2 153-651 Sentence denotes In previous studies we have shown that sulfatide (galactosylceramide-3-O-sulfate), in various species, is present in the insulin-producing cells in pancreatic islets of Langerhans. In this study the synthesis of sulfatide in the islets has been investigated by pulse chase labeling at varying glucose levels and in the presence or absence of the glycosphingolipid synthesis inhibitory agents, Brefeldin A, fumonisin B1 and chloroquine and the distribution of sulfatide by immune-electronmicroscopy.
T3 652-1077 Sentence denotes The data showed that (1) sulfatide was produced in islets of Langerhans, (2) the main pathway for synthesis was through recycling involving partial degradation in the lysosome, and that (3) high glucose levels, although not primarily reflected in an increased synthesis of sulfatide, lead to an increased expression of mRNA for the UDP-galactose:ceramide galactosyltransferase, producing the immediate precursor of sulfatide.
T4 1078-1335 Sentence denotes Furthermore, mass spectrometry analyses revealed a high proportion of short chain fatty acids, C16:0 (50%) and no hydroxylated forms and thus special physicochemical properties, indicating important differences between pancreatic and brain/neural sulfatide.
T5 1336-1490 Sentence denotes Immune electron microscopy revealed an intracellular expression of sulfatide in the secretory granules, the Golgi network and the lysosomes of the islets.
T6 1491-1638 Sentence denotes These results indicate that sulfatide follows the same intracellular route as insulin and suggest a functional association between these molecules.
T7 1639-1780 Sentence denotes We have raised the hypothesis that sulfatide possibly plays a role in the trafficking of insulin in the islets of Langerhans in rat pancreas.
T1 0-152 Sentence denotes The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
T2 153-333 Sentence denotes In previous studies we have shown that sulfatide (galactosylceramide-3-O-sulfate), in various species, is present in the insulin-producing cells in pancreatic islets of Langerhans.
T3 334-651 Sentence denotes In this study the synthesis of sulfatide in the islets has been investigated by pulse chase labeling at varying glucose levels and in the presence or absence of the glycosphingolipid synthesis inhibitory agents, Brefeldin A, fumonisin B1 and chloroquine and the distribution of sulfatide by immune-electronmicroscopy.
T4 652-1077 Sentence denotes The data showed that (1) sulfatide was produced in islets of Langerhans, (2) the main pathway for synthesis was through recycling involving partial degradation in the lysosome, and that (3) high glucose levels, although not primarily reflected in an increased synthesis of sulfatide, lead to an increased expression of mRNA for the UDP-galactose:ceramide galactosyltransferase, producing the immediate precursor of sulfatide.
T5 1078-1335 Sentence denotes Furthermore, mass spectrometry analyses revealed a high proportion of short chain fatty acids, C16:0 (50%) and no hydroxylated forms and thus special physicochemical properties, indicating important differences between pancreatic and brain/neural sulfatide.
T6 1336-1490 Sentence denotes Immune electron microscopy revealed an intracellular expression of sulfatide in the secretory granules, the Golgi network and the lysosomes of the islets.
T7 1491-1638 Sentence denotes These results indicate that sulfatide follows the same intracellular route as insulin and suggest a functional association between these molecules.
T8 1639-1780 Sentence denotes We have raised the hypothesis that sulfatide possibly plays a role in the trafficking of insulin in the islets of Langerhans in rat pancreas.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-152 Sentence denotes The glycosphingolipid sulfatide in the islets of Langerhans in rat pancreas is processed through recycling: possible involvement in insulin trafficking.
T2 153-651 Sentence denotes In previous studies we have shown that sulfatide (galactosylceramide-3-O-sulfate), in various species, is present in the insulin-producing cells in pancreatic islets of Langerhans. In this study the synthesis of sulfatide in the islets has been investigated by pulse chase labeling at varying glucose levels and in the presence or absence of the glycosphingolipid synthesis inhibitory agents, Brefeldin A, fumonisin B1 and chloroquine and the distribution of sulfatide by immune-electronmicroscopy.
T3 652-1077 Sentence denotes The data showed that (1) sulfatide was produced in islets of Langerhans, (2) the main pathway for synthesis was through recycling involving partial degradation in the lysosome, and that (3) high glucose levels, although not primarily reflected in an increased synthesis of sulfatide, lead to an increased expression of mRNA for the UDP-galactose:ceramide galactosyltransferase, producing the immediate precursor of sulfatide.
T4 1078-1335 Sentence denotes Furthermore, mass spectrometry analyses revealed a high proportion of short chain fatty acids, C16:0 (50%) and no hydroxylated forms and thus special physicochemical properties, indicating important differences between pancreatic and brain/neural sulfatide.
T5 1336-1490 Sentence denotes Immune electron microscopy revealed an intracellular expression of sulfatide in the secretory granules, the Golgi network and the lysosomes of the islets.
T6 1491-1638 Sentence denotes These results indicate that sulfatide follows the same intracellular route as insulin and suggest a functional association between these molecules.
T7 1639-1780 Sentence denotes We have raised the hypothesis that sulfatide possibly plays a role in the trafficking of insulin in the islets of Langerhans in rat pancreas.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 203-221 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes galactosylceramide http://www.glycoepitope.jp/epitopes/EP0074

GlyCosmos15-Lectin-Jamboree

Id Subject Object Predicate Lexical cue glycosmos_id
T1 1173-1176 Lectin denotes C16 GL_005239

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 67-75 Disease denotes pancreas MONDO:0021040
T2 1771-1779 Disease denotes pancreas MONDO:0021040

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 63-66 OrganismTaxon denotes rat 10114|10116
T3 1767-1770 OrganismTaxon denotes rat 10114|10116

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 39-59 Body_part denotes islets of Langerhans FMA:76489
T2 67-75 Body_part denotes pancreas FMA:7198
T3 312-332 Body_part denotes islets of Langerhans FMA:76489
T4 703-723 Body_part denotes islets of Langerhans FMA:76489
T5 819-827 Body_part denotes lysosome FMA:63836
T6 1312-1317 Body_part denotes brain FMA:50801
T7 1420-1438 Body_part denotes secretory granules FMA:84758
T8 1444-1457 Body_part denotes Golgi network FMA:67108
T9 1466-1475 Body_part denotes lysosomes FMA:63836
T10 1743-1763 Body_part denotes islets of Langerhans FMA:76489
T11 1771-1779 Body_part denotes pancreas FMA:7198

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 39-59 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T2 67-75 Body_part denotes pancreas http://purl.obolibrary.org/obo/MAT_0000075
T3 312-332 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T4 703-723 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T5 1312-1317 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T6 1743-1763 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/MAT_0000076
T7 1771-1779 Body_part denotes pancreas http://purl.obolibrary.org/obo/MAT_0000075

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 203-221 Glycan denotes galactosylceramide https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 63-66 OrganismTaxon denotes rat 10114|10116
T3 1767-1770 OrganismTaxon denotes rat 10114|10116

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 39-59 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T2 67-75 Body_part denotes pancreas http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040
T4 312-332 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T5 703-723 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T6 819-827 Body_part denotes lysosome http://purl.obolibrary.org/obo/GO_0005764
T7 1312-1317 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T9 1375-1388 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T10 1420-1438 Body_part denotes secretory granules http://purl.obolibrary.org/obo/GO_0030141
T11 1444-1449 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T12 1466-1475 Body_part denotes lysosomes http://purl.obolibrary.org/obo/GO_0005764
T13 1546-1559 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T14 1743-1763 Body_part denotes islets of Langerhans http://purl.obolibrary.org/obo/UBERON_0000006
T15 1771-1779 Body_part denotes pancreas http://purl.obolibrary.org/obo/UBERON_0001264|http://purl.obolibrary.org/obo/UBERON_3011040