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PubMed:10561465 JSONTXT

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Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 218-222 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T2 383-387 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T3 715-719 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T4 897-901 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T5 1478-1482 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 137-153 FMAID:196731 denotes oligosaccharides
_T2 137-153 FMAID:82742 denotes oligosaccharides
_T3 157-170 FMAID:62925 denotes glycoproteins
_T4 157-170 FMAID:167256 denotes glycoproteins
_T5 210-217 FMAID:74550 denotes luminal
_T6 210-217 FMAID:179287 denotes luminal
_T7 477-489 FMAID:212684 denotes cell surface
_T8 477-489 FMAID:200942 denotes cell surface
_T9 482-489 FMAID:146300 denotes surface
_T10 482-489 FMAID:50594 denotes surface
_T11 519-530 FMAID:196728 denotes amino acids
_T12 519-530 FMAID:82739 denotes amino acids
_T13 640-652 FMAID:212684 denotes cell surface
_T14 640-652 FMAID:200942 denotes cell surface
_T15 645-652 FMAID:146300 denotes surface
_T16 645-652 FMAID:50594 denotes surface
_T17 736-747 FMAID:82739 denotes amino acids
_T18 736-747 FMAID:196728 denotes amino acids
_T19 805-816 FMAID:82739 denotes amino acids
_T20 805-816 FMAID:196728 denotes amino acids
_T21 902-913 FMAID:82739 denotes amino acids
_T22 902-913 FMAID:196728 denotes amino acids
_T23 1085-1097 FMAID:212684 denotes cell surface
_T24 1085-1097 FMAID:200942 denotes cell surface
_T25 1090-1097 FMAID:146300 denotes surface
_T26 1090-1097 FMAID:50594 denotes surface
_T27 1311-1316 FMAID:68646 denotes cells
_T28 1311-1316 FMAID:169002 denotes cells

uniprot-human

Id Subject Object Predicate Lexical cue
T1 404-413 http://www.uniprot.org/uniprot/P63128 denotes proteases
T2 404-413 http://www.uniprot.org/uniprot/P10265 denotes proteases
T3 404-413 http://www.uniprot.org/uniprot/P63119 denotes proteases
T4 404-413 http://www.uniprot.org/uniprot/P63120 denotes proteases
T5 404-413 http://www.uniprot.org/uniprot/P63121 denotes proteases
T6 404-413 http://www.uniprot.org/uniprot/P63122 denotes proteases
T7 404-413 http://www.uniprot.org/uniprot/P63123 denotes proteases
T8 404-413 http://www.uniprot.org/uniprot/P63124 denotes proteases
T9 404-413 http://www.uniprot.org/uniprot/P63125 denotes proteases
T10 404-413 http://www.uniprot.org/uniprot/P63127 denotes proteases
T11 404-413 http://www.uniprot.org/uniprot/P63129 denotes proteases
T12 404-413 http://www.uniprot.org/uniprot/P63131 denotes proteases
T13 404-413 http://www.uniprot.org/uniprot/Q9Y6I0 denotes proteases

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 1311-1316 http://purl.bioontology.org/ontology/STY/T025 denotes cells

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-77 Sentence denotes The relationship between ST6Gal I Golgi retention and its cleavage-secretion.
TextSentencer_T2 78-171 Sentence denotes The ST6Gal I is a sialyltransferase that modifies N-linked oligosaccharides of glycoproteins.
TextSentencer_T3 172-297 Sentence denotes Previous results suggested a role for luminal stem and active domain sequences in the efficiency of ST6Gal I Golgi retention.
TextSentencer_T4 298-501 Sentence denotes Characterization of a series of STtyr isoform deletion mutants demonstrated that the stem is sensitive to proteases and that preventing cleavage in this region leads to increased cell surface expression.
TextSentencer_T5 502-664 Sentence denotes A mutant lacking amino acids 32-104 (STDelta4) is not active or cleaved and secreted like the wild type STtyr, but does exhibit increased cell surface expression.
TextSentencer_T6 665-871 Sentence denotes It is probable that the STDelta4 mutant lacks the stem region and some amino acids of the active domain because the STDelta5 mutant lacking amino acids 86-104 is also not active but is cleaved and secreted.
TextSentencer_T7 872-1109 Sentence denotes In contrast, deletion of stem amino acids between residues 32 and 86 in the STDelta1, STDelta2, and STDelta3 mutants does not inactive these enzyme forms, eliminate their cleavage and secretion, or increase their cell surface expression.
TextSentencer_T8 1110-1216 Sentence denotes Surprisingly, cleavage occurs even though the previously identified Asn63-Ser 64 cleavage site is missing.
TextSentencer_T9 1217-1317 Sentence denotes Further evaluation demonstrated that a cleavage site between Lys 40 and Glu 41 is used in COS cells.
TextSentencer_T10 1318-1483 Sentence denotes Mutagenesis of Lys 40 significantly decreased, but did not eliminate cleavage, suggesting that there are additional secondary sites of cleavage in the ST6Gal I stem.
T1 0-77 Sentence denotes The relationship between ST6Gal I Golgi retention and its cleavage-secretion.
T2 78-171 Sentence denotes The ST6Gal I is a sialyltransferase that modifies N-linked oligosaccharides of glycoproteins.
T3 172-297 Sentence denotes Previous results suggested a role for luminal stem and active domain sequences in the efficiency of ST6Gal I Golgi retention.
T4 298-501 Sentence denotes Characterization of a series of STtyr isoform deletion mutants demonstrated that the stem is sensitive to proteases and that preventing cleavage in this region leads to increased cell surface expression.
T5 502-664 Sentence denotes A mutant lacking amino acids 32-104 (STDelta4) is not active or cleaved and secreted like the wild type STtyr, but does exhibit increased cell surface expression.
T6 665-871 Sentence denotes It is probable that the STDelta4 mutant lacks the stem region and some amino acids of the active domain because the STDelta5 mutant lacking amino acids 86-104 is also not active but is cleaved and secreted.
T7 872-1109 Sentence denotes In contrast, deletion of stem amino acids between residues 32 and 86 in the STDelta1, STDelta2, and STDelta3 mutants does not inactive these enzyme forms, eliminate their cleavage and secretion, or increase their cell surface expression.
T8 1110-1216 Sentence denotes Surprisingly, cleavage occurs even though the previously identified Asn63-Ser 64 cleavage site is missing.
T9 1217-1317 Sentence denotes Further evaluation demonstrated that a cleavage site between Lys 40 and Glu 41 is used in COS cells.
T10 1318-1483 Sentence denotes Mutagenesis of Lys 40 significantly decreased, but did not eliminate cleavage, suggesting that there are additional secondary sites of cleavage in the ST6Gal I stem.
T1 0-77 Sentence denotes The relationship between ST6Gal I Golgi retention and its cleavage-secretion.
T2 78-171 Sentence denotes The ST6Gal I is a sialyltransferase that modifies N-linked oligosaccharides of glycoproteins.
T3 172-297 Sentence denotes Previous results suggested a role for luminal stem and active domain sequences in the efficiency of ST6Gal I Golgi retention.
T4 298-501 Sentence denotes Characterization of a series of STtyr isoform deletion mutants demonstrated that the stem is sensitive to proteases and that preventing cleavage in this region leads to increased cell surface expression.
T5 502-664 Sentence denotes A mutant lacking amino acids 32-104 (STDelta4) is not active or cleaved and secreted like the wild type STtyr, but does exhibit increased cell surface expression.
T6 665-871 Sentence denotes It is probable that the STDelta4 mutant lacks the stem region and some amino acids of the active domain because the STDelta5 mutant lacking amino acids 86-104 is also not active but is cleaved and secreted.
T7 872-1109 Sentence denotes In contrast, deletion of stem amino acids between residues 32 and 86 in the STDelta1, STDelta2, and STDelta3 mutants does not inactive these enzyme forms, eliminate their cleavage and secretion, or increase their cell surface expression.
T8 1110-1216 Sentence denotes Surprisingly, cleavage occurs even though the previously identified Asn63-Ser 64 cleavage site is missing.
T9 1217-1317 Sentence denotes Further evaluation demonstrated that a cleavage site between Lys 40 and Glu 41 is used in COS cells.
T10 1318-1483 Sentence denotes Mutagenesis of Lys 40 significantly decreased, but did not eliminate cleavage, suggesting that there are additional secondary sites of cleavage in the ST6Gal I stem.

GO-BP

Id Subject Object Predicate Lexical cue
T1 40-49 http://purl.obolibrary.org/obo/GO_0051235 denotes retention
T2 287-296 http://purl.obolibrary.org/obo/GO_0051235 denotes retention
T3 67-76 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T4 578-586 http://purl.obolibrary.org/obo/GO_0046903 denotes secreted
T5 862-870 http://purl.obolibrary.org/obo/GO_0046903 denotes secreted
T6 391-400 http://purl.obolibrary.org/obo/GO_0046960 denotes sensitive
T7 736-761 http://purl.obolibrary.org/obo/GO_0043041 denotes amino acids of the active
T8 736-761 http://purl.obolibrary.org/obo/GO_0043038 denotes amino acids of the active
T9 736-761 http://purl.obolibrary.org/obo/GO_0047658 denotes amino acids of the active
T10 736-761 http://purl.obolibrary.org/obo/GO_0015171 denotes amino acids of the active
T11 736-761 http://purl.obolibrary.org/obo/GO_0051957 denotes amino acids of the active
T12 736-761 http://purl.obolibrary.org/obo/GO_0004042 denotes amino acids of the active
T13 736-761 http://purl.obolibrary.org/obo/GO_0019202 denotes amino acids of the active
T14 736-761 http://purl.obolibrary.org/obo/GO_0047661 denotes amino acids of the active
T15 736-761 http://purl.obolibrary.org/obo/GO_0002161 denotes amino acids of the active
T16 1278-1281 http://purl.obolibrary.org/obo/GO_0050065 denotes Lys
T17 1333-1336 http://purl.obolibrary.org/obo/GO_0050065 denotes Lys

GO-CC

Id Subject Object Predicate Lexical cue
T1 34-39 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T2 281-286 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T3 477-481 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T4 640-644 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T5 1085-1089 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T6 1311-1316 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T7 477-489 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface
T8 640-652 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface
T9 1085-1097 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface
T10 1184-1187 http://purl.obolibrary.org/obo/GO_0005790 denotes Ser

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 241-250 http://edamontology.org/topic_3168 denotes sequences
T2 241-250 http://edamontology.org/topic_0080 denotes sequences
T3 519-530 http://edamontology.org/topic_0154 denotes amino acids
T4 671-679 http://edamontology.org/topic_2269 denotes probable
T5 736-747 http://edamontology.org/topic_0154 denotes amino acids
T6 805-816 http://edamontology.org/topic_0154 denotes amino acids
T7 902-913 http://edamontology.org/topic_0154 denotes amino acids

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 241-250 http://edamontology.org/operation_3218 denotes sequences
T2 241-250 http://edamontology.org/data_2044 denotes sequences
T3 361-373 http://edamontology.org/operation_2246 denotes demonstrated
T4 922-930 http://edamontology.org/data_1756 denotes residues
T5 1167-1177 http://edamontology.org/data_2611 denotes identified
T6 1167-1177 http://edamontology.org/data_0842 denotes identified
T7 1236-1248 http://edamontology.org/operation_2246 denotes demonstrated

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 218-222 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T2 383-387 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T3 715-719 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T4 897-901 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem
T5 1478-1482 http://purl.obolibrary.org/obo/MAT_0000239 denotes stem

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 218-222 Body_part denotes stem http://purl.obolibrary.org/obo/MAT_0000239
T2 383-387 Body_part denotes stem http://purl.obolibrary.org/obo/MAT_0000239
T3 715-719 Body_part denotes stem http://purl.obolibrary.org/obo/MAT_0000239
T4 897-901 Body_part denotes stem http://purl.obolibrary.org/obo/MAT_0000239
T5 1478-1482 Body_part denotes stem http://purl.obolibrary.org/obo/MAT_0000239

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 34-39 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T2 281-286 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794