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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-73 Sentence denotes A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome).
TextSentencer_T2 74-338 Sentence denotes Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase).
TextSentencer_T3 339-451 Sentence denotes Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children.
TextSentencer_T4 452-607 Sentence denotes Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology.
TextSentencer_T5 608-758 Sentence denotes Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent.
TextSentencer_T6 759-862 Sentence denotes Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly.
TextSentencer_T7 863-1016 Sentence denotes Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase.
TextSentencer_T8 1017-1113 Sentence denotes Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity.
TextSentencer_T9 1114-1278 Sentence denotes Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity.
TextSentencer_T10 1279-1467 Sentence denotes The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy.
T1 0-73 Sentence denotes A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome).
T2 74-338 Sentence denotes Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase).
T3 339-451 Sentence denotes Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children.
T4 452-607 Sentence denotes Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology.
T5 608-758 Sentence denotes Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent.
T6 759-862 Sentence denotes Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly.
T7 863-1016 Sentence denotes Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase.
T8 1017-1113 Sentence denotes Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity.
T9 1114-1278 Sentence denotes Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity.
T10 1279-1467 Sentence denotes The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy.
T1 0-73 Sentence denotes A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome).
T2 74-338 Sentence denotes Mucopolysaccharidosis type III A (MPS III A, Sanfilippo syndrome) is a rare, autosomal recessive, lysosomal storage disease characterized by accumulation of heparan sulfate secondary to defective function of the lysosomal enzyme heparan N- sulfatase (sulfamidase).
T3 339-451 Sentence denotes Here we describe a spontaneous mouse mutant that replicates many of the features found in MPS III A in children.
T4 452-607 Sentence denotes Brain sections revealed neurons with distended lysosomes filled with membranous and floccular materials with some having a classical zebra body morphology.
T5 608-758 Sentence denotes Storage materials were also present in lysosomes of cells of many other tissues, and these often stained positively with periodic-acid Schiff reagent.
T6 759-862 Sentence denotes Affected mice usually died at 7-10 months of age exhibiting a distended bladder and hepatosplenomegaly.
T7 863-1016 Sentence denotes Heparan sulfate isolated from urine and brain had nonreducing end glucosamine- N -sulfate residues that were digested with recombinant human sulfamidase.
T8 1017-1113 Sentence denotes Enzyme assays of liver and brain extracts revealed a dramatic reduction in sulfamidase activity.
T9 1114-1278 Sentence denotes Other lysosomal hydrolases that degrade heparan sulfate or other glycans and glycosaminoglycans were either normal, or were somewhat increased in specific activity.
T10 1279-1467 Sentence denotes The MPS III A mouse provides an excellent model for evaluating pathogenic mechanisms of disease and for testing treatment strategies, including enzyme or cell replacement and gene therapy.

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 231-246 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T2 863-878 http://www.glycoepitope.jp/epitopes/EP0086 denotes Heparan sulfate
T3 1154-1169 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 452-457 http://purl.obolibrary.org/obo/MAT_0000098 denotes Brain
T2 831-838 http://purl.obolibrary.org/obo/MAT_0000122 denotes bladder
T3 893-898 http://purl.obolibrary.org/obo/MAT_0000058 denotes urine
T4 903-908 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T5 1034-1039 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T6 1044-1049 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 74-95 HP_0008155 denotes Mucopolysaccharidosis
T2 151-170 HP_0000007 denotes autosomal recessive
T3 843-861 HP_0001433 denotes hepatosplenomegaly

ICD10

Id Subject Object Predicate Lexical cue
T1 18-39 http://purl.bioontology.org/ontology/ICD10/E76.3 denotes mucopolysaccharidosis
T2 74-95 http://purl.bioontology.org/ontology/ICD10/E76.3 denotes Mucopolysaccharidosis

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 151-160 FMAID:74406 denotes autosomal
_T2 151-160 FMAID:176862 denotes autosomal
_T3 161-170 FMAID:211293 denotes recessive
_T4 172-181 FMAID:63836 denotes lysosomal
_T5 172-181 FMAID:162299 denotes lysosomal
_T6 231-238 FMAID:67110 denotes heparan
_T7 231-238 FMAID:165191 denotes heparan
_T8 231-246 FMAID:63023 denotes heparan sulfate
_T9 231-246 FMAID:167405 denotes heparan sulfate
_T10 247-259 FMAID:55654 denotes secondary to
_T11 247-259 FMAID:198193 denotes secondary to
_T12 286-295 FMAID:63836 denotes lysosomal
_T13 286-295 FMAID:162299 denotes lysosomal
_T14 303-310 FMAID:67110 denotes heparan
_T15 303-310 FMAID:165191 denotes heparan
_T16 452-457 FMAID:146514 denotes Brain
_T17 452-457 FMAID:50801 denotes Brain
_T18 476-483 FMAID:54527 denotes neurons
_T19 476-483 FMAID:166033 denotes neurons
_T20 476-483 FMAID:150783 denotes neurons
_T21 499-508 FMAID:63836 denotes lysosomes
_T22 499-508 FMAID:162299 denotes lysosomes
_T23 521-531 FMAID:167608 denotes membranous
_T24 521-531 FMAID:93573 denotes membranous
_T25 521-531 FMAID:30322 denotes membranous
_T26 521-531 FMAID:7145 denotes membranous
_T27 591-595 FMAID:256134 denotes body
_T28 591-595 FMAID:256135 denotes body
_T29 647-656 FMAID:162299 denotes lysosomes
_T30 647-656 FMAID:63836 denotes lysosomes
_T31 647-665 FMAID:226190 denotes lysosomes of cells
_T32 647-665 FMAID:226191 denotes lysosomes of cells
_T33 660-665 FMAID:169002 denotes cells
_T34 660-665 FMAID:68646 denotes cells
_T35 680-687 FMAID:256050 denotes tissues
_T36 804-807 FMAID:276692 denotes age
_T58 1191-1209 FMAID:167395 denotes glycosaminoglycans
_T37 831-838 FMAID:106284 denotes bladder
_T38 863-870 FMAID:67110 denotes Heparan
_T39 863-870 FMAID:165191 denotes Heparan
_T40 863-878 FMAID:63023 denotes Heparan sulfate
_T41 863-878 FMAID:167405 denotes Heparan sulfate
_T42 893-898 FMAID:226785 denotes urine
_T43 903-908 FMAID:50801 denotes brain
_T44 903-908 FMAID:146514 denotes brain
_T45 929-940 FMAID:82797 denotes glucosamine
_T46 929-940 FMAID:196792 denotes glucosamine
_T47 1034-1039 FMAID:93672 denotes liver
_T48 1034-1039 FMAID:7197 denotes liver
_T49 1044-1049 FMAID:146514 denotes brain
_T50 1044-1049 FMAID:50801 denotes brain
_T51 1044-1058 FMAID:206963 denotes brain extracts
_T52 1120-1129 FMAID:63836 denotes lysosomal
_T53 1120-1129 FMAID:162299 denotes lysosomal
_T54 1154-1161 FMAID:67110 denotes heparan
_T55 1154-1161 FMAID:165191 denotes heparan
_T56 1154-1169 FMAID:63023 denotes heparan sulfate
_T57 1154-1169 FMAID:167405 denotes heparan sulfate
_T59 1191-1209 FMAID:63011 denotes glycosaminoglycans
_T60 1383-1390 FMAID:178661 denotes testing
_T61 1454-1458 FMAID:198663 denotes gene

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 151-160 http://purl.bioontology.org/ontology/NCBITAXON/150701 denotes autosomal
T2 399-403 http://purl.bioontology.org/ontology/NCBITAXON/9973 denotes many
T3 442-450 http://purl.bioontology.org/ontology/NCBITAXON/525814 denotes children
T4 536-545 http://purl.bioontology.org/ontology/NCBITAXON/144547 denotes floccular
T5 660-665 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T6 669-673 http://purl.bioontology.org/ontology/NCBITAXON/9973 denotes many
T7 680-687 http://purl.bioontology.org/ontology/STY/T024 denotes tissues
T8 794-800 http://purl.bioontology.org/ontology/NCBITAXON/23017 denotes months
T9 1353-1363 http://purl.bioontology.org/ontology/NCBITAXON/127244 denotes mechanisms

GO-BP

Id Subject Object Predicate Lexical cue
T1 182-189 http://purl.obolibrary.org/obo/GO_0051235 denotes storage
T2 608-615 http://purl.obolibrary.org/obo/GO_0051235 denotes Storage
T3 182-189 http://purl.obolibrary.org/obo/GO_0035732 denotes storage
T4 608-615 http://purl.obolibrary.org/obo/GO_0035732 denotes Storage
T5 239-246 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T6 871-878 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T7 945-952 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T8 1162-1169 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T9 804-807 http://purl.obolibrary.org/obo/GO_0007568 denotes age
T10 893-898 http://purl.obolibrary.org/obo/GO_0060073 denotes urine
T11 972-980 http://purl.obolibrary.org/obo/GO_0007586 denotes digested
T12 1146-1153 http://purl.obolibrary.org/obo/GO_0009056 denotes degrade
T13 1146-1169 http://purl.obolibrary.org/obo/GO_0030200 denotes degrade heparan sulfate

GO-CC

Id Subject Object Predicate Lexical cue
T1 151-160 http://purl.obolibrary.org/obo/GO_0030849 denotes autosomal
T2 172-181 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T3 286-295 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T4 499-508 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T5 647-656 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T6 521-531 http://purl.obolibrary.org/obo/GO_0016020 denotes membranous
T7 660-665 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8 1433-1437 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 680-687 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
T2 893-898 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine
T3 903-908 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T4 1044-1049 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T5 1034-1039 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 172-181 http://edamontology.org/topic_0616 denotes lysosomal
T2 190-197 http://edamontology.org/topic_0634 denotes disease
T3 286-295 http://edamontology.org/topic_0616 denotes lysosomal
T4 499-508 http://edamontology.org/topic_0616 denotes lysosomes
T5 647-656 http://edamontology.org/topic_0616 denotes lysosomes
T6 998-1003 http://edamontology.org/topic_2815 denotes human
T7 1120-1129 http://edamontology.org/topic_0616 denotes lysosomal
T8 1342-1352 http://edamontology.org/topic_0783 denotes pathogenic
T9 1367-1374 http://edamontology.org/topic_0634 denotes disease

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 411-419 http://edamontology.org/data_1255 denotes features
T2 953-961 http://edamontology.org/data_1756 denotes residues
T3 1222-1228 http://edamontology.org/operation_3435 denotes normal
T4 1342-1352 http://edamontology.org/data_3718 denotes pathogenic

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 452-457 http://purl.obolibrary.org/obo/MAT_0000098 denotes Brain
T2 831-838 http://purl.obolibrary.org/obo/MAT_0000122 denotes bladder
T3 893-898 http://purl.obolibrary.org/obo/MAT_0000058 denotes urine
T4 903-908 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T5 1034-1039 http://purl.obolibrary.org/obo/MAT_0000097 denotes liver
T6 1044-1049 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 231-246 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
PD-GlycoEpitope-B_T2 863-878 http://www.glycoepitope.jp/epitopes/EP0086 denotes Heparan sulfate
PD-GlycoEpitope-B_T3 1154-1169 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 680-687 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
PD-UBERON-AE-B_T2 452-457 http://purl.obolibrary.org/obo/UBERON_0000955 denotes Brain
PD-UBERON-AE-B_T3 903-908 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
PD-UBERON-AE-B_T4 1044-1049 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
PD-UBERON-AE-B_T5 1034-1039 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T6 476-483 http://purl.obolibrary.org/obo/UBERON_2000602 denotes neurons
PD-UBERON-AE-B_T7 893-898 http://purl.obolibrary.org/obo/UBERON_0001088 denotes urine

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 18-50 Disease denotes mucopolysaccharidosis type III A http://purl.obolibrary.org/obo/MONDO_0009655
T2 18-48 Disease denotes mucopolysaccharidosis type III http://purl.obolibrary.org/obo/MONDO_0018937
T3 52-71 Disease denotes Sanfilippo syndrome http://purl.obolibrary.org/obo/MONDO_0018937
T4 74-106 Disease denotes Mucopolysaccharidosis type III A http://purl.obolibrary.org/obo/MONDO_0009655
T5 74-104 Disease denotes Mucopolysaccharidosis type III http://purl.obolibrary.org/obo/MONDO_0018937
T6 108-117 Disease denotes MPS III A http://purl.obolibrary.org/obo/MONDO_0009655
T7 119-138 Disease denotes Sanfilippo syndrome http://purl.obolibrary.org/obo/MONDO_0018937
T8 172-197 Disease denotes lysosomal storage disease http://purl.obolibrary.org/obo/MONDO_0002561
T9 429-438 Disease denotes MPS III A http://purl.obolibrary.org/obo/MONDO_0009655
T10 1283-1292 Disease denotes MPS III A http://purl.obolibrary.org/obo/MONDO_0009655

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 843-861 Phenotype denotes hepatosplenomegaly HP:0001433

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 2-7 OrganismTaxon denotes mouse 10088|10090
T3 370-375 OrganismTaxon denotes mouse 10088|10090
T5 768-772 OrganismTaxon denotes mice 10088
T6 998-1003 OrganismTaxon denotes human 9606
T7 1293-1298 OrganismTaxon denotes mouse 10088|10090

Glycosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 231-246 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T2 863-878 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T3 1154-1169 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 452-457 Body_part denotes Brain http://purl.obolibrary.org/obo/MAT_0000098
T2 831-838 Body_part denotes bladder http://purl.obolibrary.org/obo/MAT_0000122
T3 893-898 Body_part denotes urine http://purl.obolibrary.org/obo/MAT_0000058
T4 903-908 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T5 1034-1039 Body_part denotes liver http://purl.obolibrary.org/obo/MAT_0000097
T6 1044-1049 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 452-457 Body_part denotes Brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T3 499-508 Body_part denotes lysosomes http://purl.obolibrary.org/obo/GO_0005764
T4 647-656 Body_part denotes lysosomes http://purl.obolibrary.org/obo/GO_0005764
T5 831-838 Body_part denotes bladder http://purl.obolibrary.org/obo/UBERON_0001255|http://purl.obolibrary.org/obo/UBERON_0018707
T7 893-898 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T8 903-908 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T10 1034-1039 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T11 1044-1049 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636

Glycosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 476-483 Cell denotes neurons http://purl.obolibrary.org/obo/CL:0000540