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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 83-90 https://glytoucan.org/Structures/Glycans/G00021MO denotes Heparin
T2 83-90 https://glytoucan.org/Structures/Glycans/G54161DR denotes Heparin
T3 708-715 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 708-715 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 1124-1131 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T6 1124-1131 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 83-90 Glycan_Motif denotes Heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T3 708-715 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T5 1124-1131 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-82 Sentence denotes A novel strategy to generate biologically active neo-glycosaminoglycan conjugates.
TextSentencer_T2 83-199 Sentence denotes Heparin and heparan sulfate are structurally related polysaccharides with a variety of biological effects/functions.
TextSentencer_T3 200-337 Sentence denotes Most of these effects are due to interactions, of varying specificity, between the negatively charged polysaccharide chains and proteins.
TextSentencer_T4 338-562 Sentence denotes While such interactions generally involve a single saccharide domain of decasaccharide size or less, ternary complexes of two protein molecules binding to separate domains on a single polysaccharide chain are known to occur.
TextSentencer_T5 563-763 Sentence denotes To facilitate studies on domain organization and its importance for biological function a strategy was developed to chemically conjugate defined heparin oligomers in linear and chemoselective fashion.
TextSentencer_T6 764-1030 Sentence denotes The procedure requires that the oligosaccharide to provide the reducing-terminal domain of the conjugate is generated by lyase degradation of a parent polysaccharide, whereas the nonreducing-terminal domain is obtained through deaminative cleavage with nitrous acid.
TextSentencer_T7 1031-1273 Sentence denotes The applicability of the method was demonstrated by constructing a conjugate composed of two heparin 12-mers, of which the reducing-terminal component contained the antithrombin-binding region, whereas the nonreducing-terminal domain did not.
TextSentencer_T8 1274-1411 Sentence denotes Contrary to any of the unconjugated oligomers, the product was found to efficiently promote the inactivation of thrombin by antithrombin.
T1 0-82 Sentence denotes A novel strategy to generate biologically active neo-glycosaminoglycan conjugates.
T2 83-199 Sentence denotes Heparin and heparan sulfate are structurally related polysaccharides with a variety of biological effects/functions.
T3 200-337 Sentence denotes Most of these effects are due to interactions, of varying specificity, between the negatively charged polysaccharide chains and proteins.
T4 338-562 Sentence denotes While such interactions generally involve a single saccharide domain of decasaccharide size or less, ternary complexes of two protein molecules binding to separate domains on a single polysaccharide chain are known to occur.
T5 563-763 Sentence denotes To facilitate studies on domain organization and its importance for biological function a strategy was developed to chemically conjugate defined heparin oligomers in linear and chemoselective fashion.
T6 764-1030 Sentence denotes The procedure requires that the oligosaccharide to provide the reducing-terminal domain of the conjugate is generated by lyase degradation of a parent polysaccharide, whereas the nonreducing-terminal domain is obtained through deaminative cleavage with nitrous acid.
T7 1031-1273 Sentence denotes The applicability of the method was demonstrated by constructing a conjugate composed of two heparin 12-mers, of which the reducing-terminal component contained the antithrombin-binding region, whereas the nonreducing-terminal domain did not.
T8 1274-1411 Sentence denotes Contrary to any of the unconjugated oligomers, the product was found to efficiently promote the inactivation of thrombin by antithrombin.
T1 0-82 Sentence denotes A novel strategy to generate biologically active neo-glycosaminoglycan conjugates.
T2 83-199 Sentence denotes Heparin and heparan sulfate are structurally related polysaccharides with a variety of biological effects/functions.
T3 200-337 Sentence denotes Most of these effects are due to interactions, of varying specificity, between the negatively charged polysaccharide chains and proteins.
T4 338-562 Sentence denotes While such interactions generally involve a single saccharide domain of decasaccharide size or less, ternary complexes of two protein molecules binding to separate domains on a single polysaccharide chain are known to occur.
T5 563-763 Sentence denotes To facilitate studies on domain organization and its importance for biological function a strategy was developed to chemically conjugate defined heparin oligomers in linear and chemoselective fashion.
T6 764-1030 Sentence denotes The procedure requires that the oligosaccharide to provide the reducing-terminal domain of the conjugate is generated by lyase degradation of a parent polysaccharide, whereas the nonreducing-terminal domain is obtained through deaminative cleavage with nitrous acid.
T7 1031-1273 Sentence denotes The applicability of the method was demonstrated by constructing a conjugate composed of two heparin 12-mers, of which the reducing-terminal component contained the antithrombin-binding region, whereas the nonreducing-terminal domain did not.
T8 1274-1411 Sentence denotes Contrary to any of the unconjugated oligomers, the product was found to efficiently promote the inactivation of thrombin by antithrombin.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 83-90 https://glytoucan.org/Structures/Glycans/G00021MO denotes Heparin
T2 83-90 https://glytoucan.org/Structures/Glycans/G54161DR denotes Heparin
T3 708-715 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 708-715 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 1124-1131 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T6 1124-1131 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 95-110 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 53-70 FMAID:63011 denotes glycosaminoglycan
_T2 53-70 FMAID:167395 denotes glycosaminoglycan
_T3 83-90 FMAID:167420 denotes Heparin
_T4 83-90 FMAID:82839 denotes Heparin
_T5 95-102 FMAID:165191 denotes heparan
_T6 95-102 FMAID:67110 denotes heparan
_T7 95-110 FMAID:63023 denotes heparan sulfate
_T8 95-110 FMAID:167405 denotes heparan sulfate
_T9 115-135 FMAID:167966 denotes structurally related
_T10 115-135 FMAID:50627 denotes structurally related
_T11 136-151 FMAID:196735 denotes polysaccharides
_T12 136-151 FMAID:82746 denotes polysaccharides
_T13 136-151 FMAID:196779 denotes polysaccharides
_T14 136-151 FMAID:82785 denotes polysaccharides
_T15 302-316 FMAID:82746 denotes polysaccharide
_T16 302-316 FMAID:196735 denotes polysaccharide
_T17 302-316 FMAID:196779 denotes polysaccharide
_T18 302-316 FMAID:82785 denotes polysaccharide
_T19 328-336 FMAID:165447 denotes proteins
_T20 328-336 FMAID:67257 denotes proteins
_T21 389-399 FMAID:196733 denotes saccharide
_T22 389-399 FMAID:82744 denotes saccharide
_T23 464-471 FMAID:67257 denotes protein
_T24 464-471 FMAID:165447 denotes protein
_T25 522-536 FMAID:82746 denotes polysaccharide
_T26 522-536 FMAID:82785 denotes polysaccharide
_T27 522-536 FMAID:196735 denotes polysaccharide
_T28 522-536 FMAID:196779 denotes polysaccharide
_T29 595-607 FMAID:67498 denotes organization
_T30 595-607 FMAID:166081 denotes organization
_T31 708-715 FMAID:167420 denotes heparin
_T32 708-715 FMAID:82839 denotes heparin
_T33 796-811 FMAID:196731 denotes oligosaccharide
_T34 796-811 FMAID:82742 denotes oligosaccharide
_T35 915-929 FMAID:82746 denotes polysaccharide
_T36 915-929 FMAID:196735 denotes polysaccharide
_T37 915-929 FMAID:196779 denotes polysaccharide
_T38 915-929 FMAID:82785 denotes polysaccharide
_T39 1124-1131 FMAID:167420 denotes heparin
_T40 1124-1131 FMAID:82839 denotes heparin

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 128-135 http://purl.bioontology.org/ontology/NCBITAXON/353209 denotes related
T2 631-650 http://purl.bioontology.org/ontology/STY/T039 denotes biological function

GO-BP

Id Subject Object Predicate Lexical cue
T1 71-81 http://purl.obolibrary.org/obo/GO_0000746 denotes conjugates
T2 690-699 http://purl.obolibrary.org/obo/GO_0000746 denotes conjugate
T3 859-868 http://purl.obolibrary.org/obo/GO_0000746 denotes conjugate
T4 1098-1107 http://purl.obolibrary.org/obo/GO_0000746 denotes conjugate
T5 103-110 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T6 666-675 http://purl.obolibrary.org/obo/GO_0032502 denotes developed
T7 891-902 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T8 1135-1139 http://purl.obolibrary.org/obo/GO_0016152 denotes mers

GO-MF

Id Subject Object Predicate Lexical cue
T1 482-489 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T2 1209-1216 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T3 482-489 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T4 1209-1216 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T5 482-489 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T6 1209-1216 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T7 482-489 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T8 1209-1216 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 708-715 http://rdf.glycoinfo.org/glycan/G54161DR denotes heparin
T2 1124-1131 http://rdf.glycoinfo.org/glycan/G54161DR denotes heparin

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 95-110 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 595-607 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organization

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-82 Sentence denotes A novel strategy to generate biologically active neo-glycosaminoglycan conjugates.
T2 83-199 Sentence denotes Heparin and heparan sulfate are structurally related polysaccharides with a variety of biological effects/functions.
T3 200-337 Sentence denotes Most of these effects are due to interactions, of varying specificity, between the negatively charged polysaccharide chains and proteins.
T4 338-562 Sentence denotes While such interactions generally involve a single saccharide domain of decasaccharide size or less, ternary complexes of two protein molecules binding to separate domains on a single polysaccharide chain are known to occur.
T5 563-763 Sentence denotes To facilitate studies on domain organization and its importance for biological function a strategy was developed to chemically conjugate defined heparin oligomers in linear and chemoselective fashion.
T6 764-1030 Sentence denotes The procedure requires that the oligosaccharide to provide the reducing-terminal domain of the conjugate is generated by lyase degradation of a parent polysaccharide, whereas the nonreducing-terminal domain is obtained through deaminative cleavage with nitrous acid.
T7 1031-1273 Sentence denotes The applicability of the method was demonstrated by constructing a conjugate composed of two heparin 12-mers, of which the reducing-terminal component contained the antithrombin-binding region, whereas the nonreducing-terminal domain did not.
T8 1274-1411 Sentence denotes Contrary to any of the unconjugated oligomers, the product was found to efficiently promote the inactivation of thrombin by antithrombin.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 95-110 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086