PubMed:10528860
Annnotations
PMID_GLOBAL
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 0-45 | DiseaseOrPhenotypicFeature | denotes | Maternal uniparental disomy for chromosome 14 | 0019915 |
| T2 | 106-151 | DiseaseOrPhenotypicFeature | denotes | maternal uniparental disomy for chromosome 14 | 0019915 |
| T3 | 181-183 | DiseaseOrPhenotypicFeature | denotes | he | 0017319 |
| T4 | 247-268 | DiseaseOrPhenotypicFeature | denotes | Prader-Willi syndrome | 0008300 |
| T5 | 270-273 | DiseaseOrPhenotypicFeature | denotes | PWS | 0008300 |
| T6 | 301-308 | DiseaseOrPhenotypicFeature | denotes | obesity | 0011122 |
| T7 | 336-350 | DiseaseOrPhenotypicFeature | denotes | cryptorchidism | 0009047 |
| T8 | 417-448 | DiseaseOrPhenotypicFeature | denotes | intrauterine growth retardation | 0005030 |
| T9 | 547-549 | DiseaseOrPhenotypicFeature | denotes | he | 0017319 |
| T10 | 667-669 | DiseaseOrPhenotypicFeature | denotes | he | 0017319 |
| T11 | 857-874 | DiseaseOrPhenotypicFeature | denotes | sleep disturbance | 0100081 |
| T12 | 934-955 | DiseaseOrPhenotypicFeature | denotes | Prader-Willi syndrome | 0008300 |
| T13 | 997-999 | DiseaseOrPhenotypicFeature | denotes | he | 0017319 |
| T14 | 1059-1062 | DiseaseOrPhenotypicFeature | denotes | PWS | 0008300 |
| T15 | 1125-1143 | DiseaseOrPhenotypicFeature | denotes | precocious puberty | 0000088 |
| T16 | 1574-1577 | DiseaseOrPhenotypicFeature | denotes | PWS | 0008300 |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 286-299 | HP_0004322 | denotes | short stature |
| T2 | 301-308 | HP_0001513 | denotes | obesity |
| T3 | 315-334 | HP_0001263 | denotes | developmental delay |
| T4 | 336-350 | HP_0000028 | denotes | cryptorchidism |
| T5 | 417-448 | HP_0001511 | denotes | intrauterine growth retardation |
| T6 | 430-448 | HP_0001510 | denotes | growth retardation |
| T7 | 557-566 | HP_0001252 | denotes | hypotonia |
| T8 | 572-584 | HP_0002033 | denotes | poor sucking |
| T9 | 677-682 | HP_0001513 | denotes | obese |
| T10 | 750-754 | HP_0012531 | denotes | pain |
| T11 | 1125-1143 | HP_0000826 | denotes | precocious puberty |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 10528860-17#68#71#gene7389 | 1539-1542 | gene7389 | denotes | UPD |
| 10528860-17#103#106#diseaseC0032897 | 1574-1577 | diseaseC0032897 | denotes | PWS |
| 68#71#gene7389103#106#diseaseC0032897 | 10528860-17#68#71#gene7389 | 10528860-17#103#106#diseaseC0032897 | associated_with | UPD,PWS |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 720-730 | http://purl.obolibrary.org/obo/UBERON_0001756 | denotes | middle ear |
| PD-UBERON-AE-B_T2 | 727-730 | http://purl.obolibrary.org/obo/UBERON_0001690 | denotes | ear |
PubCasesHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| AB1 | 286-299 | HP:0004322 | denotes | short stature |
| AB2 | 301-308 | HP:0001513 | denotes | obesity |
| AB3 | 336-350 | HP:0000028 | denotes | cryptorchidism |
| AB4 | 417-448 | HP:0001511 | denotes | intrauterine growth retardation |
| AB5 | 572-584 | HP:0002033 | denotes | poor sucking |
| AB6 | 750-754 | HP:0012531 | denotes | pain |
| AB7 | 857-874 | HP:0002360 | denotes | sleep disturbance |
| AB8 | 1125-1143 | HP:0000826 | denotes | precocious puberty |
PubCasesORDO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| AB1 | 247-268 | ORDO:739 | denotes | Prader-Willi syndrome |
| AB2 | 934-955 | ORDO:739 | denotes | Prader-Willi syndrome |
| AB3 | 1059-1067 | ORDO:398073 | denotes | PWS-like |
| AB4 | 1574-1582 | ORDO:398073 | denotes | PWS-like |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 720-730 | http://purl.obolibrary.org/obo/UBERON_0001756 | denotes | middle ear |
| PD-UBERON-AE-B_T2 | 727-730 | http://purl.obolibrary.org/obo/UBERON_0001690 | denotes | ear |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-79 | Sentence | denotes | Maternal uniparental disomy for chromosome 14 in a boy with a normal karyotype. |
| TextSentencer_T2 | 80-162 | Sentence | denotes | We report on a boy with a maternal uniparental disomy for chromosome 14 (UPD(14)). |
| TextSentencer_T3 | 163-275 | Sentence | denotes | At 7 years of age he was referred to us by the paediatrician because of symptoms of Prader-Willi syndrome (PWS). |
| TextSentencer_T4 | 276-386 | Sentence | denotes | He showed short stature, obesity, mild developmental delay, cryptorchidism, and some mild dysmorphic features. |
| TextSentencer_T5 | 387-477 | Sentence | denotes | The history further indicated intrauterine growth retardation at the end of the pregnancy. |
| TextSentencer_T6 | 478-534 | Sentence | denotes | His mother was 44 years of age at the time of his birth. |
| TextSentencer_T7 | 535-622 | Sentence | denotes | After birth he showed hypotonia with poor sucking, for which gavage feeding was needed. |
| TextSentencer_T8 | 623-653 | Sentence | denotes | Motor development was delayed. |
| TextSentencer_T9 | 654-709 | Sentence | denotes | After 1 year he became obese despite a normal appetite. |
| TextSentencer_T10 | 710-818 | Sentence | denotes | Recurrent middle ear infections, a high pain threshold, and a great skill with jigsaw puzzles were reported. |
| TextSentencer_T11 | 819-875 | Sentence | denotes | There were no behavioural problems or sleep disturbance. |
| TextSentencer_T12 | 876-916 | Sentence | denotes | Chromosomal analysis was normal (46,XY). |
| TextSentencer_T13 | 917-980 | Sentence | denotes | DNA analysis for Prader-Willi syndrome showed no abnormalities. |
| TextSentencer_T14 | 981-1111 | Sentence | denotes | Two years later he was re-examined because we thought his features fitted the PWS-like phenotype associated with maternal UPD(14). |
| TextSentencer_T15 | 1112-1156 | Sentence | denotes | At that time precocious puberty was evident. |
| TextSentencer_T16 | 1157-1217 | Sentence | denotes | DNA analysis showed maternal heterodisomy for chromosome 14. |
| TextSentencer_T17 | 1218-1384 | Sentence | denotes | In all the previously described 11 cases with maternal UPD(14), a Robertsonian translocation involving chromosome 14 was detected cytogenetically before DNA analysis. |
| TextSentencer_T18 | 1385-1470 | Sentence | denotes | This is the first report of diagnosis of maternal UPD(14) based on clinical features. |
| TextSentencer_T19 | 1471-1686 | Sentence | denotes | This finding underlines the importance of DNA analysis for maternal UPD(14) in patients with a similar PWS-like phenotype even without previous identification of a Robertsonian translocation involving chromosome 14. |
| T1 | 0-79 | Sentence | denotes | Maternal uniparental disomy for chromosome 14 in a boy with a normal karyotype. |
| T2 | 80-162 | Sentence | denotes | We report on a boy with a maternal uniparental disomy for chromosome 14 (UPD(14)). |
| T3 | 163-275 | Sentence | denotes | At 7 years of age he was referred to us by the paediatrician because of symptoms of Prader-Willi syndrome (PWS). |
| T4 | 276-386 | Sentence | denotes | He showed short stature, obesity, mild developmental delay, cryptorchidism, and some mild dysmorphic features. |
| T5 | 387-477 | Sentence | denotes | The history further indicated intrauterine growth retardation at the end of the pregnancy. |
| T6 | 478-534 | Sentence | denotes | His mother was 44 years of age at the time of his birth. |
| T7 | 535-622 | Sentence | denotes | After birth he showed hypotonia with poor sucking, for which gavage feeding was needed. |
| T8 | 623-653 | Sentence | denotes | Motor development was delayed. |
| T9 | 654-709 | Sentence | denotes | After 1 year he became obese despite a normal appetite. |
| T10 | 710-818 | Sentence | denotes | Recurrent middle ear infections, a high pain threshold, and a great skill with jigsaw puzzles were reported. |
| T11 | 819-875 | Sentence | denotes | There were no behavioural problems or sleep disturbance. |
| T12 | 876-916 | Sentence | denotes | Chromosomal analysis was normal (46,XY). |
| T13 | 917-980 | Sentence | denotes | DNA analysis for Prader-Willi syndrome showed no abnormalities. |
| T14 | 981-1111 | Sentence | denotes | Two years later he was re-examined because we thought his features fitted the PWS-like phenotype associated with maternal UPD(14). |
| T15 | 1112-1156 | Sentence | denotes | At that time precocious puberty was evident. |
| T16 | 1157-1217 | Sentence | denotes | DNA analysis showed maternal heterodisomy for chromosome 14. |
| T17 | 1218-1384 | Sentence | denotes | In all the previously described 11 cases with maternal UPD(14), a Robertsonian translocation involving chromosome 14 was detected cytogenetically before DNA analysis. |
| T18 | 1385-1470 | Sentence | denotes | This is the first report of diagnosis of maternal UPD(14) based on clinical features. |
| T19 | 1471-1686 | Sentence | denotes | This finding underlines the importance of DNA analysis for maternal UPD(14) in patients with a similar PWS-like phenotype even without previous identification of a Robertsonian translocation involving chromosome 14. |
NCBIDiseaseCorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T17 | 1103-1106 | SpecificDisease:D024182 | denotes | UPD |
| T1 | 0-45 | SpecificDisease:D024182 | denotes | Maternal uniparental disomy for chromosome 14 |
| T2 | 106-151 | SpecificDisease:D024182 | denotes | maternal uniparental disomy for chromosome 14 |
| T3 | 153-156 | SpecificDisease:D024182 | denotes | UPD |
| T4 | 247-268 | SpecificDisease:D011218 | denotes | Prader-Willi syndrome |
| T5 | 270-273 | SpecificDisease:D011218 | denotes | PWS |
| T6 | 286-299 | DiseaseClass:D006130 | denotes | short stature |
| T7 | 301-308 | SpecificDisease:D009765 | denotes | obesity |
| T8 | 315-334 | DiseaseClass:D002658 | denotes | developmental delay |
| T9 | 336-350 | SpecificDisease:D003456 | denotes | cryptorchidism |
| T10 | 366-385 | DiseaseClass:D000013 | denotes | dysmorphic features |
| T11 | 417-448 | DiseaseClass:D005317 | denotes | intrauterine growth retardation |
| T12 | 557-566 | DiseaseClass:D009123 | denotes | hypotonia |
| T13 | 677-682 | Modifier:D009765 | denotes | obese |
| T14 | 720-741 | SpecificDisease:D010033 | denotes | middle ear infections |
| T15 | 934-955 | SpecificDisease:D011218 | denotes | Prader-Willi syndrome |
| T16 | 1059-1062 | Modifier:D011218 | denotes | PWS |
| T18 | 1177-1198 | DiseaseClass:D024182 | denotes | maternal heterodisomy |
| T19 | 1273-1276 | SpecificDisease:D024182 | denotes | UPD |
| T20 | 1435-1438 | SpecificDisease:D024182 | denotes | UPD |
| T21 | 1574-1577 | Modifier:D011218 | denotes | PWS |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 1539-1542 | gene:7389 | denotes | UPD |
| T1 | 1574-1577 | disease:C0032897 | denotes | PWS |
| R1 | T0 | T1 | associated_with | UPD,PWS |
NCBI-Disease-Train
| Id | Subject | Object | Predicate | Lexical cue | database_id |
|---|---|---|---|---|---|
| T3032 | 0-45 | SpecificDisease | denotes | Maternal uniparental disomy for chromosome 14 | D024182 |
| T3033 | 106-151 | SpecificDisease | denotes | maternal uniparental disomy for chromosome 14 | D024182 |
| T3034 | 153-156 | SpecificDisease | denotes | UPD | D024182 |
| T3035 | 247-268 | SpecificDisease | denotes | Prader-Willi syndrome | D011218 |
| T3036 | 270-273 | SpecificDisease | denotes | PWS | D011218 |
| T3037 | 286-299 | DiseaseClass | denotes | short stature | D006130 |
| T3038 | 301-308 | SpecificDisease | denotes | obesity | D009765 |
| T3039 | 315-334 | DiseaseClass | denotes | developmental delay | D002658 |
| T3040 | 336-350 | SpecificDisease | denotes | cryptorchidism | D003456 |
| T3041 | 366-385 | DiseaseClass | denotes | dysmorphic features | D000013 |
| T3042 | 417-448 | DiseaseClass | denotes | intrauterine growth retardation | D005317 |
| T3043 | 557-566 | DiseaseClass | denotes | hypotonia | D009123 |
| T3044 | 677-682 | Modifier | denotes | obese | D009765 |
| T3045 | 720-741 | SpecificDisease | denotes | middle ear infections | D010033 |
| T3046 | 934-955 | SpecificDisease | denotes | Prader-Willi syndrome | D011218 |
| T3047 | 1059-1062 | Modifier | denotes | PWS | D011218 |
| T3048 | 1103-1106 | SpecificDisease | denotes | UPD | D024182 |
| T3049 | 1177-1198 | DiseaseClass | denotes | maternal heterodisomy | D024182 |
| T3050 | 1273-1276 | SpecificDisease | denotes | UPD | D024182 |
| T3051 | 1435-1438 | SpecificDisease | denotes | UPD | D024182 |
| T3052 | 1574-1577 | Modifier | denotes | PWS | D011218 |
NCBI-Disease-Corpus-All
| Id | Subject | Object | Predicate | Lexical cue | database_id |
|---|---|---|---|---|---|
| T3032 | 0-45 | SpecificDisease | denotes | Maternal uniparental disomy for chromosome 14 | D024182 |
| T3033 | 106-151 | SpecificDisease | denotes | maternal uniparental disomy for chromosome 14 | D024182 |
| T3034 | 153-156 | SpecificDisease | denotes | UPD | D024182 |
| T3035 | 247-268 | SpecificDisease | denotes | Prader-Willi syndrome | D011218 |
| T3036 | 270-273 | SpecificDisease | denotes | PWS | D011218 |
| T3037 | 286-299 | DiseaseClass | denotes | short stature | D006130 |
| T3038 | 301-308 | SpecificDisease | denotes | obesity | D009765 |
| T3039 | 315-334 | DiseaseClass | denotes | developmental delay | D002658 |
| T3040 | 336-350 | SpecificDisease | denotes | cryptorchidism | D003456 |
| T3041 | 366-385 | DiseaseClass | denotes | dysmorphic features | D000013 |
| T3042 | 417-448 | DiseaseClass | denotes | intrauterine growth retardation | D005317 |
| T3043 | 557-566 | DiseaseClass | denotes | hypotonia | D009123 |
| T3044 | 677-682 | Modifier | denotes | obese | D009765 |
| T3045 | 720-741 | SpecificDisease | denotes | middle ear infections | D010033 |
| T3046 | 934-955 | SpecificDisease | denotes | Prader-Willi syndrome | D011218 |
| T3047 | 1059-1062 | Modifier | denotes | PWS | D011218 |
| T3048 | 1103-1106 | SpecificDisease | denotes | UPD | D024182 |
| T3049 | 1177-1198 | DiseaseClass | denotes | maternal heterodisomy | D024182 |
| T3050 | 1273-1276 | SpecificDisease | denotes | UPD | D024182 |
| T3051 | 1435-1438 | SpecificDisease | denotes | UPD | D024182 |
| T3052 | 1574-1577 | Modifier | denotes | PWS | D011218 |
NCBI-Disease-Corpus-2stage-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 247-268 | SpecificDisease | denotes | Prader-Willi syndrome |
| T2 | 270-273 | SpecificDisease | denotes | PWS |
| T3 | 934-955 | SpecificDisease | denotes | Prader-Willi syndrome |
| T4 | 1059-1062 | Modifier | denotes | PWS |
| T5 | 1574-1577 | Modifier | denotes | PWS |
NCBI-Disease-Corpus-rezarta-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 247-268 | SpecificDisease | denotes | Prader-Willi syndrome |
| T2 | 270-273 | SpecificDisease | denotes | PWS |
| T3 | 934-955 | SpecificDisease | denotes | Prader-Willi syndrome |
| T4 | 1059-1077 | DiseaseClass | denotes | PWS-like phenotype |
| T5 | 1574-1592 | DiseaseClass | denotes | PWS-like phenotype |
NCBI-Disease-Corpus-4oGuideline-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 247-268 | SpecificDisease | denotes | Prader-Willi syndrome |
| T2 | 934-955 | SpecificDisease | denotes | Prader-Willi syndrome |
NCBI-Disease-Corpus-Simple-All
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 32-45 | SpecificDisease | denotes | chromosome 14 |
| T2 | 138-161 | SpecificDisease | denotes | chromosome 14 (UPD(14)) |
| T3 | 247-274 | SpecificDisease | denotes | Prader-Willi syndrome (PWS) |
| T4 | 286-299 | Modifier | denotes | short stature |
| T5 | 301-308 | Modifier | denotes | obesity |
| T6 | 310-334 | Modifier | denotes | mild developmental delay |
| T7 | 336-350 | Modifier | denotes | cryptorchidism |
| T8 | 361-385 | Modifier | denotes | mild dysmorphic features |
| T9 | 417-448 | Modifier | denotes | intrauterine growth retardation |
| T10 | 557-584 | Modifier | denotes | hypotonia with poor sucking |
| T11 | 623-652 | Modifier | denotes | Motor development was delayed |
| T12 | 677-682 | Modifier | denotes | obese |
| T13 | 710-741 | DiseaseClass | denotes | Recurrent middle ear infections |
| T14 | 833-853 | Modifier | denotes | behavioural problems |
| T15 | 857-874 | Modifier | denotes | sleep disturbance |
| T16 | 934-955 | SpecificDisease | denotes | Prader-Willi syndrome |
| T17 | 1059-1110 | CompositeMention | denotes | PWS-like phenotype associated with maternal UPD(14) |
| T18 | 1125-1143 | Modifier | denotes | precocious puberty |
| T19 | 1177-1216 | SpecificDisease | denotes | maternal heterodisomy for chromosome 14 |
| T20 | 1264-1280 | SpecificDisease | denotes | maternal UPD(14) |
| T21 | 1284-1334 | Modifier | denotes | Robertsonian translocation involving chromosome 14 |
| T22 | 1426-1442 | SpecificDisease | denotes | maternal UPD(14) |
| T23 | 1530-1546 | SpecificDisease | denotes | maternal UPD(14) |
| T24 | 1574-1592 | CompositeMention | denotes | PWS-like phenotype |
| T25 | 1635-1685 | Modifier | denotes | Robertsonian translocation involving chromosome 14 |