| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-107 |
Sentence |
denotes |
Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. |
| T2 |
108-287 |
Sentence |
denotes |
Lipid particles of the yeast Saccharomyces cerevisiae were isolated at high purity, and their proteins were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. |
| T3 |
288-428 |
Sentence |
denotes |
Major lipid particle proteins were identified by mass spectrometric analysis, and the corresponding open reading frames (ORFs) were deduced. |
| T4 |
429-594 |
Sentence |
denotes |
In silicio analysis revealed that all lipid particle proteins contain several hydrophobic domains but none or only few (hypothetical) transmembrane spanning regions. |
| T5 |
595-798 |
Sentence |
denotes |
All lipid particle proteins identified by function so far, such as Erg1p, Erg6p, and Erg7p (ergosterol biosynthesis) and Faa1p, Faa4p, and Fat1p (fatty acid metabolism), are involved in lipid metabolism. |
| T6 |
799-911 |
Sentence |
denotes |
Based on sequence homology, another group of three lipid particle proteins may be involved in lipid degradation. |
| T7 |
912-1119 |
Sentence |
denotes |
To examine whether lipid particle proteins of unknown function are also involved in lipid synthesis, mutants with deletions of the respective ORFs were constructed and subjected to systematic lipid analysis. |
| T8 |
1120-1251 |
Sentence |
denotes |
Deletion of YDL193w resulted in a lethal phenotype which could not be suppressed by supplementation with ergosterol or fatty acids. |
| T9 |
1252-1313 |
Sentence |
denotes |
Other deletion mutants were viable under standard conditions. |
| T10 |
1314-1538 |
Sentence |
denotes |
Strains with YBR177c, YMR313c, and YKL140w deleted exhibited phospholipid and/or neutral lipid patterns that were different from the wild-type strain and thus may be further candidate ORFs involved in yeast lipid metabolism. |