PubMed:10515935
Annnotations
PMID_GLOBAL
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-107 | Sentence | denotes | Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. |
T2 | 108-287 | Sentence | denotes | Lipid particles of the yeast Saccharomyces cerevisiae were isolated at high purity, and their proteins were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. |
T3 | 288-428 | Sentence | denotes | Major lipid particle proteins were identified by mass spectrometric analysis, and the corresponding open reading frames (ORFs) were deduced. |
T4 | 429-594 | Sentence | denotes | In silicio analysis revealed that all lipid particle proteins contain several hydrophobic domains but none or only few (hypothetical) transmembrane spanning regions. |
T5 | 595-798 | Sentence | denotes | All lipid particle proteins identified by function so far, such as Erg1p, Erg6p, and Erg7p (ergosterol biosynthesis) and Faa1p, Faa4p, and Fat1p (fatty acid metabolism), are involved in lipid metabolism. |
T6 | 799-911 | Sentence | denotes | Based on sequence homology, another group of three lipid particle proteins may be involved in lipid degradation. |
T7 | 912-1119 | Sentence | denotes | To examine whether lipid particle proteins of unknown function are also involved in lipid synthesis, mutants with deletions of the respective ORFs were constructed and subjected to systematic lipid analysis. |
T8 | 1120-1251 | Sentence | denotes | Deletion of YDL193w resulted in a lethal phenotype which could not be suppressed by supplementation with ergosterol or fatty acids. |
T9 | 1252-1313 | Sentence | denotes | Other deletion mutants were viable under standard conditions. |
T10 | 1314-1538 | Sentence | denotes | Strains with YBR177c, YMR313c, and YKL140w deleted exhibited phospholipid and/or neutral lipid patterns that were different from the wild-type strain and thus may be further candidate ORFs involved in yeast lipid metabolism. |
PubmedHPO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 769-797 | HP_0003119 | denotes | involved in lipid metabolism |
LocText
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 45-59 | go:GO:0005811 | denotes | lipid particle |
T2 | 76-81 | taxonomy:4932 | denotes | yeast |
T3 | 82-106 | taxonomy:4932 | denotes | Saccharomyces cerevisiae |
T4 | 108-123 | go:GO:0005811 | denotes | Lipid particles |
T5 | 131-136 | taxonomy:4932 | denotes | yeast |
T6 | 137-161 | taxonomy:4932 | denotes | Saccharomyces cerevisiae |
T7 | 294-308 | go:GO:0005811 | denotes | lipid particle |
T8 | 467-481 | go:GO:0005811 | denotes | lipid particle |
T9 | 563-576 | go:GO:0016020 | denotes | transmembrane |
T10 | 599-613 | go:GO:0005811 | denotes | lipid particle |
T11 | 662-667 | uniprot:Q12809 | denotes | Erg1p |
T12 | 669-674 | uniprot:P25087 | denotes | Erg6p |
T13 | 680-685 | uniprot:P38604 | denotes | Erg7p |
T14 | 716-721 | uniprot:P30624 | denotes | Faa1p |
T15 | 723-728 | uniprot:P47912 | denotes | Faa4p |
T16 | 734-739 | uniprot:P38225 | denotes | Fat1p |
T17 | 850-864 | go:GO:0005811 | denotes | lipid particle |
T18 | 931-945 | go:GO:0005811 | denotes | lipid particle |
T19 | 1132-1139 | uniprot:Q12063 | denotes | YDL193w |
T20 | 1327-1334 | uniprot:P38295 | denotes | YBR177c |
T21 | 1336-1343 | uniprot:P40308 | denotes | YMR313c |
T22 | 1349-1356 | uniprot:P34163 | denotes | YKL140w |
T23 | 1515-1520 | taxonomy:4932 | denotes | yeast |
R1 | T11 | T10 | localizeTo | Erg1p,lipid particle |
R2 | T12 | T10 | localizeTo | Erg6p,lipid particle |
R3 | T13 | T10 | localizeTo | Erg7p,lipid particle |
R4 | T14 | T10 | localizeTo | Faa1p,lipid particle |
R5 | T15 | T10 | localizeTo | Faa4p,lipid particle |
R6 | T16 | T10 | localizeTo | Fat1p,lipid particle |
R7 | T21 | T18 | localizeTo | YMR313c,lipid particle |
R8 | T22 | T18 | localizeTo | YKL140w,lipid particle |
R9 | T19 | T18 | localizeTo | YDL193w,lipid particle |
R10 | T20 | T18 | localizeTo | YBR177c,lipid particle |