PubMed:10492038
Annnotations
Inflammaging
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-224 | Sentence | denotes | Immunocytochemical analysis of MNDA in tissue sections and sorted normal bone marrow cells documents expression only in maturing normal and neoplastic myelomonocytic cells and a subset of normal and neoplastic B lymphocytes. |
| T2 | 225-366 | Sentence | denotes | The human myeloid cell nuclear differentiation antigen (MNDA) is a nuclear antigen known to be expressed in mature myelomonocytic cell lines. |
| T3 | 367-570 | Sentence | denotes | An extensive immunocytochemical evaluation of fixed tissues confirmed MNDA expression in normal maturing granulocytes and monocytes and in acute nonlymphocytic leukemias and chronic myelogenous leukemia. |
| T4 | 571-719 | Sentence | denotes | MNDA was not detected in normal tissue histiocytes but was found in activated macrophages and foreign body giant cells associated with inflammation. |
| T5 | 720-839 | Sentence | denotes | Flow cytometric cell sorting of normal bone marrow established that MNDA is initially expressed in myeloid blast cells. |
| T6 | 840-1000 | Sentence | denotes | Examination of lymphoid tissues showed a low level of expression in a population of normal mande B lymphocytes but not in germinal center cells or plasma cells. |
| T7 | 1001-1174 | Sentence | denotes | A subset of B cell neoplasms expressing MNDA included hairy cell leukemia, parafollicular (monocytoid) B cell lymphoma, mantle cell lymphoma, and small lymphocytic lymphoma. |
| T8 | 1175-1261 | Sentence | denotes | Cell sorting of normal bone marrow showed MNDA expression in CD20+/CD10-/CD5- B cells. |
| T9 | 1262-1348 | Sentence | denotes | MNDA was not detected in other normal bone marrow or all other nonhematopoietic cells. |
| T10 | 1349-1720 | Sentence | denotes | The hematopoietic cell-specific pattern of MNDA expression was elucidated through a comprehensive analysis of normal and neoplastic tissues, and the results provide further evidence of the coexpression of B- and myeloid cell markers in neoplastic B cells and identify a normal B cell population that might be related to the cell of origin of a subset of B cell neoplasms. |
| T1 | 0-224 | Sentence | denotes | Immunocytochemical analysis of MNDA in tissue sections and sorted normal bone marrow cells documents expression only in maturing normal and neoplastic myelomonocytic cells and a subset of normal and neoplastic B lymphocytes. |
| T2 | 225-366 | Sentence | denotes | The human myeloid cell nuclear differentiation antigen (MNDA) is a nuclear antigen known to be expressed in mature myelomonocytic cell lines. |
| T3 | 367-570 | Sentence | denotes | An extensive immunocytochemical evaluation of fixed tissues confirmed MNDA expression in normal maturing granulocytes and monocytes and in acute nonlymphocytic leukemias and chronic myelogenous leukemia. |
| T4 | 571-719 | Sentence | denotes | MNDA was not detected in normal tissue histiocytes but was found in activated macrophages and foreign body giant cells associated with inflammation. |
| T5 | 720-839 | Sentence | denotes | Flow cytometric cell sorting of normal bone marrow established that MNDA is initially expressed in myeloid blast cells. |
| T6 | 840-1000 | Sentence | denotes | Examination of lymphoid tissues showed a low level of expression in a population of normal mande B lymphocytes but not in germinal center cells or plasma cells. |
| T7 | 1001-1174 | Sentence | denotes | A subset of B cell neoplasms expressing MNDA included hairy cell leukemia, parafollicular (monocytoid) B cell lymphoma, mantle cell lymphoma, and small lymphocytic lymphoma. |
| T8 | 1175-1261 | Sentence | denotes | Cell sorting of normal bone marrow showed MNDA expression in CD20+/CD10-/CD5- B cells. |
| T9 | 1262-1348 | Sentence | denotes | MNDA was not detected in other normal bone marrow or all other nonhematopoietic cells. |
| T10 | 1349-1720 | Sentence | denotes | The hematopoietic cell-specific pattern of MNDA expression was elucidated through a comprehensive analysis of normal and neoplastic tissues, and the results provide further evidence of the coexpression of B- and myeloid cell markers in neoplastic B cells and identify a normal B cell population that might be related to the cell of origin of a subset of B cell neoplasms. |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 527-536 | HP_0001909 | denotes | leukemias |
| T2 | 541-569 | HP_0005506 | denotes | chronic myelogenous leukemia |
| T3 | 561-569 | HP_0001909 | denotes | leukemia |
| T4 | 1020-1029 | HP_0002664 | denotes | neoplasms |
| T5 | 1066-1074 | HP_0001909 | denotes | leukemia |
| T6 | 1104-1119 | HP_0012191 | denotes | B cell lymphoma |
| T7 | 1111-1119 | HP_0002665 | denotes | lymphoma |
| T8 | 1133-1141 | HP_0002665 | denotes | lymphoma |
| T9 | 1165-1173 | HP_0002665 | denotes | lymphoma |
| T10 | 1710-1719 | HP_0002664 | denotes | neoplasms |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 31-35 | protein | denotes | MNDA |
| T2 | 281-285 | protein | denotes | MNDA |
| T3 | 437-441 | protein | denotes | MNDA |
| T4 | 456-484 | cell_type | denotes | normal maturing granulocytes |
| T5 | 489-498 | cell_type | denotes | monocytes |
| T6 | 571-575 | protein | denotes | MNDA |
| T7 | 639-660 | cell_type | denotes | activated macrophages |
| T8 | 665-689 | cell_type | denotes | foreign body giant cells |
| T9 | 788-792 | protein | denotes | MNDA |
| T10 | 819-838 | cell_type | denotes | myeloid blast cells |
| T11 | 931-950 | cell_line | denotes | mande B lymphocytes |
| T12 | 962-983 | cell_type | denotes | germinal center cells |
| T13 | 987-999 | cell_type | denotes | plasma cells |
| T14 | 1013-1029 | cell_type | denotes | B cell neoplasms |
| T15 | 1041-1045 | protein | denotes | MNDA |
| T16 | 1217-1221 | protein | denotes | MNDA |
| T17 | 1236-1240 | protein | denotes | CD20 |
| T18 | 1253-1260 | cell_type | denotes | B cells |
| T19 | 1262-1266 | protein | denotes | MNDA |
| T20 | 1325-1347 | cell_type | denotes | nonhematopoietic cells |
| T21 | 1392-1396 | protein | denotes | MNDA |
| T22 | 1554-1581 | protein | denotes | B- and myeloid cell markers |
| T23 | 1585-1603 | cell_type | denotes | neoplastic B cells |
| T24 | 1619-1643 | cell_type | denotes | normal B cell population |
| T25 | 1703-1719 | cell_type | denotes | B cell neoplasms |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-224 | Sentence | denotes | Immunocytochemical analysis of MNDA in tissue sections and sorted normal bone marrow cells documents expression only in maturing normal and neoplastic myelomonocytic cells and a subset of normal and neoplastic B lymphocytes. |
| S2 | 225-366 | Sentence | denotes | The human myeloid cell nuclear differentiation antigen (MNDA) is a nuclear antigen known to be expressed in mature myelomonocytic cell lines. |
| S3 | 367-570 | Sentence | denotes | An extensive immunocytochemical evaluation of fixed tissues confirmed MNDA expression in normal maturing granulocytes and monocytes and in acute nonlymphocytic leukemias and chronic myelogenous leukemia. |
| S4 | 571-719 | Sentence | denotes | MNDA was not detected in normal tissue histiocytes but was found in activated macrophages and foreign body giant cells associated with inflammation. |
| S5 | 720-839 | Sentence | denotes | Flow cytometric cell sorting of normal bone marrow established that MNDA is initially expressed in myeloid blast cells. |
| S6 | 840-1000 | Sentence | denotes | Examination of lymphoid tissues showed a low level of expression in a population of normal mande B lymphocytes but not in germinal center cells or plasma cells. |
| S7 | 1001-1174 | Sentence | denotes | A subset of B cell neoplasms expressing MNDA included hairy cell leukemia, parafollicular (monocytoid) B cell lymphoma, mantle cell lymphoma, and small lymphocytic lymphoma. |
| S8 | 1175-1261 | Sentence | denotes | Cell sorting of normal bone marrow showed MNDA expression in CD20+/CD10-/CD5- B cells. |
| S9 | 1262-1348 | Sentence | denotes | MNDA was not detected in other normal bone marrow or all other nonhematopoietic cells. |
| S10 | 1349-1720 | Sentence | denotes | The hematopoietic cell-specific pattern of MNDA expression was elucidated through a comprehensive analysis of normal and neoplastic tissues, and the results provide further evidence of the coexpression of B- and myeloid cell markers in neoplastic B cells and identify a normal B cell population that might be related to the cell of origin of a subset of B cell neoplasms. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C17 | 31-35 | NP | denotes | MNDA |
| C21 | 199-223 | NP | denotes | neoplastic B lymphocytes |
| C1 | 225-286 | NP | denotes | The human myeloid cell nuclear differentiation antigen (MNDA) |
| C20 | 437-452 | NP | denotes | MNDA expression |
| C3 | 571-575 | NP | denotes | MNDA |
| C18 | 752-770 | NP | denotes | normal bone marrow |
| C4 | 788-792 | NP | denotes | MNDA |
| C5 | 1041-1045 | NP | denotes | MNDA |
| C19 | 1191-1209 | NP | denotes | normal bone marrow |
| C6 | 1217-1232 | NP | denotes | MNDA expression |
| C7 | 1262-1266 | NP | denotes | MNDA |
| C8 | 1392-1407 | NP | denotes | MNDA expression |
| C13 | 1585-1603 | NP | denotes | neoplastic B cells |
| C22 | 1617-1643 | NP | denotes | a normal B cell population |
| C23 | 1644-1648 | NP | denotes | that |
| R1 | C1 | C17 | coref-ident | The human myeloid cell nuclear differentiation antigen (MNDA),MNDA |
| R2 | C3 | C1 | coref-ident | MNDA,The human myeloid cell nuclear differentiation antigen (MNDA) |
| R3 | C4 | C3 | coref-ident | MNDA,MNDA |
| R4 | C5 | C4 | coref-ident | MNDA,MNDA |
| R5 | C19 | C18 | coref-ident | normal bone marrow,normal bone marrow |
| R6 | C6 | C20 | coref-ident | MNDA expression,MNDA expression |
| R7 | C7 | C5 | coref-ident | MNDA,MNDA |
| R8 | C8 | C6 | coref-ident | MNDA expression,MNDA expression |
| R9 | C13 | C21 | coref-ident | neoplastic B cells,neoplastic B lymphocytes |
| R10 | C23 | C22 | coref-relat | that,a normal B cell population |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-27 | other_name | denotes | Immunocytochemical analysis |
| T2 | 31-35 | protein_molecule | denotes | MNDA |
| T3 | 281-285 | protein_molecule | denotes | MNDA |
| T4 | 437-441 | protein_molecule | denotes | MNDA |
| T5 | 456-484 | cell_type | denotes | normal maturing granulocytes |
| T6 | 489-498 | cell_type | denotes | monocytes |
| T7 | 506-536 | other_name | denotes | acute nonlymphocytic leukemias |
| T8 | 541-569 | other_name | denotes | chronic myelogenous leukemia |
| T9 | 571-575 | protein_molecule | denotes | MNDA |
| T10 | 639-660 | cell_type | denotes | activated macrophages |
| T11 | 665-689 | cell_type | denotes | foreign body giant cells |
| T12 | 706-718 | other_name | denotes | inflammation |
| T13 | 720-748 | other_name | denotes | Flow cytometric cell sorting |
| T14 | 752-770 | tissue | denotes | normal bone marrow |
| T15 | 788-792 | protein_molecule | denotes | MNDA |
| T16 | 819-838 | cell_type | denotes | myeloid blast cells |
| T17 | 855-871 | tissue | denotes | lymphoid tissues |
| T18 | 931-950 | cell_line | denotes | mande B lymphocytes |
| T19 | 962-983 | cell_type | denotes | germinal center cells |
| T20 | 987-999 | cell_type | denotes | plasma cells |
| T21 | 1013-1029 | cell_type | denotes | B cell neoplasms |
| T22 | 1041-1045 | protein_molecule | denotes | MNDA |
| T23 | 1055-1074 | other_name | denotes | hairy cell leukemia |
| T24 | 1076-1119 | other_name | denotes | parafollicular (monocytoid) B cell lymphoma |
| T25 | 1121-1141 | other_name | denotes | mantle cell lymphoma |
| T26 | 1147-1173 | other_name | denotes | small lymphocytic lymphoma |
| T27 | 1191-1209 | tissue | denotes | normal bone marrow |
| T28 | 1217-1221 | protein_molecule | denotes | MNDA |
| T29 | 1236-1240 | protein_molecule | denotes | CD20 |
| T30 | 1253-1260 | cell_type | denotes | B cells |
| T31 | 1262-1266 | protein_molecule | denotes | MNDA |
| T32 | 1293-1311 | tissue | denotes | normal bone marrow |
| T33 | 1325-1347 | cell_type | denotes | nonhematopoietic cells |
| T34 | 1353-1388 | other_name | denotes | hematopoietic cell-specific pattern |
| T35 | 1392-1396 | protein_molecule | denotes | MNDA |
| T36 | 1585-1603 | cell_type | denotes | neoplastic B cells |
| T37 | 1619-1643 | cell_type | denotes | normal B cell population |
| T38 | 1703-1719 | cell_type | denotes | B cell neoplasms |