PubMed:10491763
Annnotations
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 291 | 0-27 | GeneOrGeneProduct | denotes | Hepatocyte nuclear factor-6 | NCBIGene:3175 |
| 292 | 74-90 | DiseaseOrPhenotypicFeature | denotes | type II diabetes | MESH:D003924 |
| 293 | 140-147 | GeneOrGeneProduct | denotes | insulin | NCBIGene:3630 |
| 294 | 201-234 | GeneOrGeneProduct | denotes | hepatocyte nuclear factor (HNF)-6 | NCBIGene:3175 |
| 295 | 309-332 | DiseaseOrPhenotypicFeature | denotes | maturity-onset diabetes | MESH:D003924 |
| 296 | 406-411 | GeneOrGeneProduct | denotes | HNF-6 | NCBIGene:3175 |
| 297 | 447-496 | DiseaseOrPhenotypicFeature | denotes | Type II (non-insulin-dependent) diabetes mellitus | MESH:D003924 |
| 298 | 514-521 | GeneOrGeneProduct | denotes | insulin | NCBIGene:3630 |
| 299 | 535-542 | ChemicalEntity | denotes | glucose | MESH:D005947 |
| 300 | 644-649 | GeneOrGeneProduct | denotes | HNF-6 | NCBIGene:3175 |
| 301 | 700-704 | GeneOrGeneProduct | denotes | MODY | NCBIGene:3172|NCBIGene:3651|NCBIGene:6927 |
| 302 | 739-744 | GeneOrGeneProduct | denotes | MODY1 | NCBIGene:3172 |
| 303 | 746-751 | GeneOrGeneProduct | denotes | MODY3 | NCBIGene:6927 |
| 304 | 756-761 | GeneOrGeneProduct | denotes | MODY4 | NCBIGene:3651 |
| 305 | 778-786 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 306 | 803-819 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | MESH:D003924 |
| 307 | 1101-1110 | SequenceVariant | denotes | Pro75 Ala | DBSNP:rs74805019 |
| 308 | 1174-1182 | SequenceVariant | denotes | Pro75Ala | DBSNP:rs74805019 |
| 309 | 1247-1255 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 310 | 1261-1286 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes mellitus | MESH:D003924 |
| 311 | 1335-1342 | ChemicalEntity | denotes | glucose | MESH:D005947 |
| 312 | 1410-1417 | ChemicalEntity | denotes | glucose | MESH:D005947 |
| 313 | 1444-1451 | ChemicalEntity | denotes | glucose | MESH:D005947 |
| 314 | 1474-1490 | DiseaseOrPhenotypicFeature | denotes | Type II diabetic | MESH:D003924 |
| 315 | 1491-1499 | OrganismTaxon | denotes | patients | NCBITaxon:9606 |
| 316 | 1604-1611 | ChemicalEntity | denotes | glucose | MESH:D005947 |
| 317 | 1626-1633 | GeneOrGeneProduct | denotes | insulin | NCBIGene:3630 |
| 318 | 1637-1646 | GeneOrGeneProduct | denotes | C-peptide | NCBIGene:3630 |
| 319 | 1723-1728 | GeneOrGeneProduct | denotes | HNF-6 | NCBIGene:3175 |
| 320 | 1758-1774 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | MESH:D003924 |
| 321 | 1794-1801 | GeneOrGeneProduct | denotes | insulin | NCBIGene:3630 |
| 322 | 1815-1822 | ChemicalEntity | denotes | glucose | MESH:D005947 |
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-158 | Sentence | denotes | Hepatocyte nuclear factor-6: associations between genetic variability and type II diabetes and between genetic variability and estimates of insulin secretion. |
| T2 | 159-175 | Sentence | denotes | AIMS/HYPOTHESIS: |
| T3 | 176-346 | Sentence | denotes | The transcription factor hepatocyte nuclear factor (HNF)-6 is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. |
| T4 | 347-561 | Sentence | denotes | We therefore tested the hypothesis that variability in the HNF-6 gene is associated with subsets of Type II (non-insulin-dependent) diabetes mellitus and estimates of insulin secretion in glucose tolerant subjects. |
| T5 | 562-570 | Sentence | denotes | METHODS: |
| T6 | 571-655 | Sentence | denotes | We cloned the coding region as well as the intron-exon boundaries of the HNF-6 gene. |
| T7 | 656-949 | Sentence | denotes | We then examined them on genomic DNA in six MODY probands without mutations in the MODY1, MODY3 and MODY4 genes and in 54 patients with late-onset Type II diabetes by combined single strand conformational polymorphism-heteroduplex analysis followed by direct sequencing of identified variants. |
| T8 | 950-1048 | Sentence | denotes | An identified missense variant was examined in association studies and genotype-phenotype studies. |
| T9 | 1049-1057 | Sentence | denotes | RESULTS: |
| T10 | 1058-1120 | Sentence | denotes | We identified two silent and one missense (Pro75 Ala) variant. |
| T11 | 1121-1369 | Sentence | denotes | In an association study the allelic frequency of the Pro75Ala polymorphism was 3.2% (95% confidence interval, 1.9-4.5) in 330 patients with Type II diabetes mellitus compared with 4.2% (2.4-6.0) in 238 age-matched glucose tolerant control subjects. |
| T12 | 1370-1657 | Sentence | denotes | Moreover, in studies of 238 middle-aged glucose tolerant subjects, of 226 glucose tolerant offspring of Type II diabetic patients and of 367 young healthy subjects, the carriers of the polymorphism did not differ from non-carriers in glucose induced serum insulin or C-peptide responses. |
| T13 | 1658-1684 | Sentence | denotes | CONCLUSION/INTERPRETATION: |
| T14 | 1685-1853 | Sentence | denotes | Mutations in the coding region of the HNF-6 gene are not associated with Type II diabetes or with changes in insulin responses to glucose among the Caucasians examined. |
LitCoin_Mondo
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 309-345 | DiseaseOrPhenotypicFeature | denotes | maturity-onset diabetes of the young | 0018911 |
| T2 | 479-496 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | 0005015 |
| T3 | 1269-1286 | DiseaseOrPhenotypicFeature | denotes | diabetes mellitus | 0005015 |
LitCoin-SeqVar
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1101-1110 | SequenceVariant | denotes | Pro75 Ala |
| T2 | 1174-1182 | SequenceVariant | denotes | Pro75Ala |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 19-25 | GeneOrGeneProduct | denotes | factor |
| T2 | 74-81 | GeneOrGeneProduct | denotes | type II |
| T3 | 82-90 | GeneOrGeneProduct | denotes | diabetes |
| T4 | 140-147 | GeneOrGeneProduct | denotes | insulin |
| T5 | 180-200 | GeneOrGeneProduct | denotes | transcription factor |
| T6 | 201-226 | GeneOrGeneProduct | denotes | hepatocyte nuclear factor |
| T7 | 228-231 | GeneOrGeneProduct | denotes | HNF |
| T8 | 250-259 | GeneOrGeneProduct | denotes | regulator |
| T9 | 324-332 | GeneOrGeneProduct | denotes | diabetes |
| T10 | 340-345 | GeneOrGeneProduct | denotes | young |
| T11 | 406-411 | GeneOrGeneProduct | denotes | HNF-6 |
| T12 | 406-409 | GeneOrGeneProduct | denotes | HNF |
| T13 | 447-454 | GeneOrGeneProduct | denotes | Type II |
| T14 | 460-467 | GeneOrGeneProduct | denotes | insulin |
| T15 | 479-487 | GeneOrGeneProduct | denotes | diabetes |
| T16 | 514-521 | GeneOrGeneProduct | denotes | insulin |
| T17 | 543-551 | GeneOrGeneProduct | denotes | tolerant |
| T18 | 644-649 | GeneOrGeneProduct | denotes | HNF-6 |
| T19 | 644-647 | GeneOrGeneProduct | denotes | HNF |
| T20 | 700-704 | GeneOrGeneProduct | denotes | MODY |
| T21 | 739-744 | GeneOrGeneProduct | denotes | MODY1 |
| T22 | 746-751 | GeneOrGeneProduct | denotes | MODY3 |
| T23 | 756-761 | GeneOrGeneProduct | denotes | MODY4 |
| T24 | 803-810 | GeneOrGeneProduct | denotes | Type II |
| T25 | 811-819 | GeneOrGeneProduct | denotes | diabetes |
| T26 | 1157-1166 | GeneOrGeneProduct | denotes | frequency |
| T27 | 1261-1268 | GeneOrGeneProduct | denotes | Type II |
| T28 | 1269-1277 | GeneOrGeneProduct | denotes | diabetes |
| T29 | 1343-1351 | GeneOrGeneProduct | denotes | tolerant |
| T30 | 1418-1426 | GeneOrGeneProduct | denotes | tolerant |
| T31 | 1452-1460 | GeneOrGeneProduct | denotes | tolerant |
| T32 | 1474-1481 | GeneOrGeneProduct | denotes | Type II |
| T33 | 1511-1516 | GeneOrGeneProduct | denotes | young |
| T34 | 1626-1633 | GeneOrGeneProduct | denotes | insulin |
| T35 | 1637-1646 | GeneOrGeneProduct | denotes | C-peptide |
| T36 | 1723-1728 | GeneOrGeneProduct | denotes | HNF-6 |
| T37 | 1723-1726 | GeneOrGeneProduct | denotes | HNF |
| T38 | 1758-1765 | GeneOrGeneProduct | denotes | Type II |
| T39 | 1766-1774 | GeneOrGeneProduct | denotes | diabetes |
| T40 | 1794-1801 | GeneOrGeneProduct | denotes | insulin |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 19-25 | GeneOrGeneProduct | denotes | factor |
| T2 | 74-81 | GeneOrGeneProduct | denotes | type II |
| T3 | 82-90 | GeneOrGeneProduct | denotes | diabetes |
| T4 | 140-147 | GeneOrGeneProduct | denotes | insulin |
| T5 | 148-157 | GeneOrGeneProduct | denotes | secretion |
| T6 | 180-200 | GeneOrGeneProduct | denotes | transcription factor |
| T7 | 201-226 | GeneOrGeneProduct | denotes | hepatocyte nuclear factor |
| T8 | 227-234 | GeneOrGeneProduct | denotes | (HNF)-6 |
| T9 | 228-231 | GeneOrGeneProduct | denotes | HNF |
| T10 | 250-259 | GeneOrGeneProduct | denotes | regulator |
| T11 | 309-317 | GeneOrGeneProduct | denotes | maturity |
| T12 | 324-332 | GeneOrGeneProduct | denotes | diabetes |
| T13 | 340-345 | GeneOrGeneProduct | denotes | young |
| T14 | 360-366 | GeneOrGeneProduct | denotes | tested |
| T15 | 406-411 | GeneOrGeneProduct | denotes | HNF-6 |
| T16 | 406-409 | GeneOrGeneProduct | denotes | HNF |
| T17 | 447-454 | GeneOrGeneProduct | denotes | Type II |
| T18 | 460-467 | GeneOrGeneProduct | denotes | insulin |
| T19 | 479-487 | GeneOrGeneProduct | denotes | diabetes |
| T20 | 514-521 | GeneOrGeneProduct | denotes | insulin |
| T21 | 522-531 | GeneOrGeneProduct | denotes | secretion |
| T22 | 543-551 | GeneOrGeneProduct | denotes | tolerant |
| T23 | 562-569 | GeneOrGeneProduct | denotes | METHODS |
| T24 | 574-584 | GeneOrGeneProduct | denotes | cloned the |
| T25 | 644-649 | GeneOrGeneProduct | denotes | HNF-6 |
| T26 | 644-647 | GeneOrGeneProduct | denotes | HNF |
| T27 | 673-677 | GeneOrGeneProduct | denotes | them |
| T28 | 700-704 | GeneOrGeneProduct | denotes | MODY |
| T29 | 722-731 | GeneOrGeneProduct | denotes | mutations |
| T30 | 739-744 | GeneOrGeneProduct | denotes | MODY1 |
| T31 | 746-751 | GeneOrGeneProduct | denotes | MODY3 |
| T32 | 756-761 | GeneOrGeneProduct | denotes | MODY4 |
| T33 | 762-777 | GeneOrGeneProduct | denotes | genes and in 54 |
| T34 | 792-796 | GeneOrGeneProduct | denotes | late |
| T35 | 803-810 | GeneOrGeneProduct | denotes | Type II |
| T36 | 811-819 | GeneOrGeneProduct | denotes | diabetes |
| T37 | 839-845 | GeneOrGeneProduct | denotes | strand |
| T38 | 964-972 | GeneOrGeneProduct | denotes | missense |
| T39 | 1091-1099 | GeneOrGeneProduct | denotes | missense |
| T40 | 1107-1110 | GeneOrGeneProduct | denotes | Ala |
| T41 | 1157-1166 | GeneOrGeneProduct | denotes | frequency |
| T42 | 1261-1268 | GeneOrGeneProduct | denotes | Type II |
| T43 | 1269-1277 | GeneOrGeneProduct | denotes | diabetes |
| T44 | 1343-1351 | GeneOrGeneProduct | denotes | tolerant |
| T45 | 1418-1426 | GeneOrGeneProduct | denotes | tolerant |
| T46 | 1452-1460 | GeneOrGeneProduct | denotes | tolerant |
| T47 | 1474-1481 | GeneOrGeneProduct | denotes | Type II |
| T48 | 1482-1490 | GeneOrGeneProduct | denotes | diabetic |
| T49 | 1511-1516 | GeneOrGeneProduct | denotes | young |
| T50 | 1539-1547 | GeneOrGeneProduct | denotes | carriers |
| T51 | 1592-1600 | GeneOrGeneProduct | denotes | carriers |
| T52 | 1612-1619 | GeneOrGeneProduct | denotes | induced |
| T53 | 1626-1633 | GeneOrGeneProduct | denotes | insulin |
| T54 | 1637-1646 | GeneOrGeneProduct | denotes | C-peptide |
| T55 | 1685-1694 | GeneOrGeneProduct | denotes | Mutations |
| T56 | 1723-1728 | GeneOrGeneProduct | denotes | HNF-6 |
| T57 | 1723-1726 | GeneOrGeneProduct | denotes | HNF |
| T58 | 1758-1765 | GeneOrGeneProduct | denotes | Type II |
| T59 | 1766-1774 | GeneOrGeneProduct | denotes | diabetes |
| T60 | 1794-1801 | GeneOrGeneProduct | denotes | insulin |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 82-90 | DiseaseOrPhenotypicFeature | denotes | diabetes | DISEASE |
| T2 | 309-332 | DiseaseOrPhenotypicFeature | denotes | maturity-onset diabetes | D003924 |
| T3 | 455-496 | DiseaseOrPhenotypicFeature | denotes | (non-insulin-dependent) diabetes mellitus | D003924 |
| T4 | 700-704 | DiseaseOrPhenotypicFeature | denotes | MODY | D003924 |
| T5 | 739-744 | DiseaseOrPhenotypicFeature | denotes | MODY1 | C565101 |
| T6 | 746-751 | DiseaseOrPhenotypicFeature | denotes | MODY3 | C563933 |
| T7 | 756-761 | DiseaseOrPhenotypicFeature | denotes | MODY4 | C563451 |
| T8 | 811-819 | DiseaseOrPhenotypicFeature | denotes | diabetes | DISEASE |
| T9 | 1261-1286 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes mellitus | D003924 |
| T10 | 1482-1490 | DiseaseOrPhenotypicFeature | denotes | diabetic | DISEASE |
| T11 | 1766-1774 | DiseaseOrPhenotypicFeature | denotes | diabetes | DISEASE |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-27 | GeneOrGeneProduct | denotes | Hepatocyte nuclear factor-6 |
| T2 | 180-200 | GeneOrGeneProduct | denotes | transcription factor |
| T3 | 201-234 | GeneOrGeneProduct | denotes | hepatocyte nuclear factor (HNF)-6 |
| T4 | 406-411 | GeneOrGeneProduct | denotes | HNF-6 |
| T5 | 644-649 | GeneOrGeneProduct | denotes | HNF-6 |
| T6 | 700-704 | GeneOrGeneProduct | denotes | MODY |
| T7 | 739-744 | GeneOrGeneProduct | denotes | MODY1 |
| T8 | 746-751 | GeneOrGeneProduct | denotes | MODY3 |
| T9 | 756-761 | GeneOrGeneProduct | denotes | MODY4 |
| T10 | 1723-1728 | GeneOrGeneProduct | denotes | HNF-6 |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 74-90 | DiseaseOrPhenotypicFeature | denotes | type II diabetes | 0005148 |
| T2 | 309-345 | DiseaseOrPhenotypicFeature | denotes | maturity-onset diabetes of the young | 0018911 |
| T3 | 455-496 | DiseaseOrPhenotypicFeature | denotes | (non-insulin-dependent) diabetes mellitus | 0005148 |
| T4 | 700-704 | DiseaseOrPhenotypicFeature | denotes | MODY | 0018911 |
| T5 | 739-744 | DiseaseOrPhenotypicFeature | denotes | MODY1 | 0007452 |
| T6 | 746-751 | DiseaseOrPhenotypicFeature | denotes | MODY3 | 0010894 |
| T7 | 756-761 | DiseaseOrPhenotypicFeature | denotes | MODY4 | 0011667 |
| T8 | 803-819 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | 0005148 |
| T9 | 1261-1286 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes mellitus | 0005148 |
| T10 | 1758-1774 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | 0005148 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 74-90 | DiseaseOrPhenotypicFeature | denotes | type II diabetes | DISEASE |
| T2 | 309-345 | DiseaseOrPhenotypicFeature | denotes | maturity-onset diabetes of the young | C562772 |
| T3 | 455-496 | DiseaseOrPhenotypicFeature | denotes | (non-insulin-dependent) diabetes mellitus | D003924 |
| T4 | 700-704 | DiseaseOrPhenotypicFeature | denotes | MODY | D003924 |
| T5 | 739-744 | DiseaseOrPhenotypicFeature | denotes | MODY1 | C565101 |
| T6 | 746-751 | DiseaseOrPhenotypicFeature | denotes | MODY3 | C563933 |
| T7 | 756-761 | DiseaseOrPhenotypicFeature | denotes | MODY4 | C563451 |
| T8 | 803-819 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | DISEASE |
| T9 | 1261-1286 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes mellitus | D003924 |
| T10 | 1474-1490 | DiseaseOrPhenotypicFeature | denotes | Type II diabetic | DISEASE |
| T11 | 1758-1774 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | DISEASE |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 74-90 | DiseaseOrPhenotypicFeature | denotes | type II diabetes | DISEASE |
| T2 | 309-345 | DiseaseOrPhenotypicFeature | denotes | maturity-onset diabetes of the young | C562772 |
| T3 | 455-496 | DiseaseOrPhenotypicFeature | denotes | (non-insulin-dependent) diabetes mellitus | D003924 |
| T4 | 700-704 | DiseaseOrPhenotypicFeature | denotes | MODY | D003924 |
| T5 | 739-744 | DiseaseOrPhenotypicFeature | denotes | MODY1 | C565101 |
| T6 | 746-751 | DiseaseOrPhenotypicFeature | denotes | MODY3 | C563933 |
| T7 | 756-761 | DiseaseOrPhenotypicFeature | denotes | MODY4 | C563451 |
| T8 | 803-819 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | DISEASE |
| T9 | 1261-1286 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes mellitus | D003924 |
| T10 | 1474-1490 | DiseaseOrPhenotypicFeature | denotes | Type II diabetic | DISEASE |
| T11 | 1758-1774 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | DISEASE |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 778-786 | OrganismTaxon | denotes | patients |
| T2 | 1107-1110 | OrganismTaxon | denotes | Ala |
| T3 | 1247-1255 | OrganismTaxon | denotes | patients |
| T4 | 1491-1499 | OrganismTaxon | denotes | patients |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 535-542 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
| T4 | 1107-1110 | ChemicalEntity | denotes | Ala | http://purl.obolibrary.org/obo/CHEBI_46217|http://purl.obolibrary.org/obo/CHEBI_16977 |
| T6 | 1335-1342 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
| T9 | 1410-1417 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
| T12 | 1444-1451 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
| T15 | 1604-1611 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
| T18 | 1637-1646 | ChemicalEntity | denotes | C-peptide | http://purl.obolibrary.org/obo/CHEBI_80332 |
| T19 | 1815-1822 | ChemicalEntity | denotes | glucose | D005947|http://purl.obolibrary.org/obo/CHEBI_4167|http://purl.obolibrary.org/obo/CHEBI_17234 |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T19 | 1815-1822 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
| T18 | 1637-1646 | ChemicalEntity | denotes | C-peptide | http://purl.obolibrary.org/obo/CHEBI_80332 | |
| T15 | 1604-1611 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
| T12 | 1444-1451 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
| T9 | 1410-1417 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
| T6 | 1335-1342 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
| T4 | 1107-1110 | ChemicalEntity | denotes | Ala | http://purl.obolibrary.org/obo/CHEBI_16977|http://purl.obolibrary.org/obo/CHEBI_46217 | |
| T1 | 535-542 | ChemicalEntity | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167|D005947 | |
| T10 | 1723-1728 | GeneOrGeneProduct | denotes | HNF-6 | ||
| T87491 | 756-761 | GeneOrGeneProduct | denotes | MODY4 | ||
| T8 | 746-751 | GeneOrGeneProduct | denotes | MODY3 | ||
| T7 | 739-744 | GeneOrGeneProduct | denotes | MODY1 | ||
| T97864 | 700-704 | GeneOrGeneProduct | denotes | MODY | ||
| T5 | 644-649 | GeneOrGeneProduct | denotes | HNF-6 | ||
| T46743 | 406-411 | GeneOrGeneProduct | denotes | HNF-6 | ||
| T3 | 201-234 | GeneOrGeneProduct | denotes | hepatocyte nuclear factor (HNF)-6 | ||
| T2 | 180-200 | GeneOrGeneProduct | denotes | transcription factor | ||
| T37196 | 0-27 | GeneOrGeneProduct | denotes | Hepatocyte nuclear factor-6 | ||
| T11 | 1758-1774 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | DISEASE | |
| T81151 | 1474-1490 | DiseaseOrPhenotypicFeature | denotes | Type II diabetic | DISEASE | |
| T98683 | 1261-1286 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes mellitus | D003924 | |
| T64979 | 803-819 | DiseaseOrPhenotypicFeature | denotes | Type II diabetes | DISEASE | |
| T70991 | 756-761 | DiseaseOrPhenotypicFeature | denotes | MODY4 | C563451 | |
| T39812 | 746-751 | DiseaseOrPhenotypicFeature | denotes | MODY3 | C563933 | |
| T36474 | 739-744 | DiseaseOrPhenotypicFeature | denotes | MODY1 | C565101 | |
| T70469 | 700-704 | DiseaseOrPhenotypicFeature | denotes | MODY | D003924 | |
| T77034 | 455-496 | DiseaseOrPhenotypicFeature | denotes | (non-insulin-dependent) diabetes mellitus | D003924 | |
| T56652 | 309-345 | DiseaseOrPhenotypicFeature | denotes | maturity-onset diabetes of the young | C562772 | |
| T4097 | 74-90 | DiseaseOrPhenotypicFeature | denotes | type II diabetes | DISEASE | |
| T34631 | 1491-1499 | OrganismTaxon | denotes | patients | ||
| T69782 | 1247-1255 | OrganismTaxon | denotes | patients | ||
| T42533 | 1107-1110 | OrganismTaxon | denotes | Ala | ||
| T36905 | 778-786 | OrganismTaxon | denotes | patients | ||
| T74030 | 1174-1182 | SequenceVariant | denotes | Pro75Ala | ||
| T1719 | 1101-1110 | SequenceVariant | denotes | Pro75 Ala |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 309-345 | HP_0004904 | denotes | maturity-onset diabetes of the young |
| T2 | 479-496 | HP_0000819 | denotes | diabetes mellitus |
DisGeNET5_variant_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 10491763-7#53#61#geners74805019 | 1174-1182 | geners74805019 | denotes | Pro75Ala |
| 10491763-7#140#165#diseaseC0011860 | 1261-1286 | diseaseC0011860 | denotes | Type II diabetes mellitus |
| 53#61#geners74805019140#165#diseaseC0011860 | 10491763-7#53#61#geners74805019 | 10491763-7#140#165#diseaseC0011860 | associated_with | Pro75Ala,Type II diabetes mellitus |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 10491763-0#0#27#gene3175 | 0-27 | gene3175 | denotes | Hepatocyte nuclear factor-6 |
| 10491763-0#74#90#diseaseC0011860 | 74-90 | diseaseC0011860 | denotes | type II diabetes |
| 10491763-4#100#105#gene3651 | 756-761 | gene3651 | denotes | MODY4 |
| 10491763-4#147#163#diseaseC0011860 | 803-819 | diseaseC0011860 | denotes | Type II diabetes |
| 0#27#gene317574#90#diseaseC0011860 | 10491763-0#0#27#gene3175 | 10491763-0#74#90#diseaseC0011860 | associated_with | Hepatocyte nuclear factor-6,type II diabetes |
| 100#105#gene3651147#163#diseaseC0011860 | 10491763-4#100#105#gene3651 | 10491763-4#147#163#diseaseC0011860 | associated_with | MODY4,Type II diabetes |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 0-27 | gene:3175 | denotes | Hepatocyte nuclear factor-6 |
| T1 | 74-90 | disease:C0011860 | denotes | type II diabetes |
| T2 | 140-147 | gene:3630 | denotes | insulin |
| T3 | 74-90 | disease:C0011860 | denotes | type II diabetes |
| T4 | 140-147 | gene:723961 | denotes | insulin |
| T5 | 74-90 | disease:C0011860 | denotes | type II diabetes |
| T6 | 406-411 | gene:3175 | denotes | HNF-6 |
| T7 | 456-496 | disease:C0011860 | denotes | non-insulin-dependent) diabetes mellitus |
| T8 | 756-761 | gene:3651 | denotes | MODY4 |
| T9 | 803-819 | disease:C0011860 | denotes | Type II diabetes |
| T10 | 1794-1801 | gene:3630 | denotes | insulin |
| T11 | 1758-1774 | disease:C0011860 | denotes | Type II diabetes |
| T12 | 1794-1801 | gene:723961 | denotes | insulin |
| T13 | 1758-1774 | disease:C0011860 | denotes | Type II diabetes |
| T14 | 1723-1728 | gene:3175 | denotes | HNF-6 |
| T15 | 1758-1774 | disease:C0011860 | denotes | Type II diabetes |
| R1 | T0 | T1 | associated_with | Hepatocyte nuclear factor-6,type II diabetes |
| R2 | T2 | T3 | associated_with | insulin,type II diabetes |
| R3 | T4 | T5 | associated_with | insulin,type II diabetes |
| R4 | T6 | T7 | associated_with | HNF-6,non-insulin-dependent) diabetes mellitus |
| R5 | T8 | T9 | associated_with | MODY4,Type II diabetes |
| R6 | T10 | T11 | associated_with | insulin,Type II diabetes |
| R7 | T12 | T13 | associated_with | insulin,Type II diabetes |
| R8 | T14 | T15 | associated_with | HNF-6,Type II diabetes |