PubMed:10488147
Annnotations
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1262-1273 | Cell | denotes | eosinophils | http://purl.obolibrary.org/obo/CL:0000771 |
| T2 | 1278-1287 | Cell | denotes | basophils | http://purl.obolibrary.org/obo/CL:0000767 |
| T3 | 1577-1587 | Cell | denotes | eosinophil | http://purl.obolibrary.org/obo/CL:0000771 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-115 | Sentence | denotes | Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. |
| T2 | 116-267 | Sentence | denotes | Previously, we mapped the novel CC chemokine myeloid progenitor inhibitory factor 2 (MPIF-2)/eotaxin-2 to chromosome 7q11.23 (Nomiyama, H., Osborne, L. |
| T3 | 268-362 | Sentence | denotes | R., Imai, T., Kusuda, J., Miura, R., Tsui, L.-C., and Yoshie, O. (1998) Genomics 49, 339-340). |
| T4 | 363-497 | Sentence | denotes | Since chemokine genes tend to be clustered, unknown chemokines may be present in the vicinity of those mapped to new chromosomal loci. |
| T5 | 498-666 | Sentence | denotes | Prompted by this hypothesis, we analyzed the genomic region containing the gene for MPIF-2/eotaxin-2 (SCYA24) and have identified a novel CC chemokine termed eotaxin-3. |
| T6 | 667-790 | Sentence | denotes | The genes for MPIF-2/eotaxin-2 (SCYA24) and eotaxin-3 (SCYA26) are localized within a region of approximately 40 kilobases. |
| T7 | 791-885 | Sentence | denotes | By Northern blot analysis, eotaxin-3 mRNA was constitutively expressed in the heart and ovary. |
| T8 | 886-961 | Sentence | denotes | We have generated recombinant eotaxin-3 in a baculovirus expression system. |
| T9 | 962-1103 | Sentence | denotes | Eotaxin-3 induced transient calcium mobilization specifically in CC chemokine receptor 3 (CCR3)-expressing L1.2 cells with an EC(50) of 3 nM. |
| T10 | 1104-1207 | Sentence | denotes | Eotaxin-3 competed the binding of (125)I-eotaxin to CCR3-expressing L1.2 cells with an IC(50) of 13 nM. |
| T11 | 1208-1311 | Sentence | denotes | Eotaxin-3 was chemotactic for normal peripheral blood eosinophils and basophils at high concentrations. |
| T12 | 1312-1378 | Sentence | denotes | Collectively, eotaxin-3 is yet another functional ligand for CCR3. |
| T13 | 1379-1491 | Sentence | denotes | The potency of eotaxin-3 as a CCR3 ligand seems, however, to be approximately 10-fold less than that of eotaxin. |
| T14 | 1492-1645 | Sentence | denotes | Identification of eotaxin-3 will further promote our understanding of the control of eosinophil trafficking and other CCR3-mediated biological phenomena. |
| T15 | 1646-1752 | Sentence | denotes | The strategy used in this study may also be applicable to identification of other unknown chemokine genes. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 869-874 | http://purl.obolibrary.org/obo/MAT_0000036 | denotes | heart |
| T2 | 1256-1261 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T3 | 1256-1261 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
FSU-PRGE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 35-47 | protein | denotes | CC chemokine |
| T2 | 49-58 | protein | denotes | Eotaxin-3 |
| T3 | 91-114 | protein | denotes | CC chemokine receptor 3 |
| T4 | 148-160 | protein | denotes | CC chemokine |
| T5 | 161-199 | protein | denotes | myeloid progenitor inhibitory factor 2 |
| T6 | 201-207 | protein | denotes | MPIF-2 |
| T7 | 209-218 | protein | denotes | eotaxin-2 |
| T8 | 369-378 | protein | denotes | chemokine |
| T9 | 415-425 | protein | denotes | chemokines |
| T10 | 582-588 | protein | denotes | MPIF-2 |
| T11 | 589-598 | protein | denotes | eotaxin-2 |
| T12 | 600-606 | protein | denotes | SCYA24 |
| T13 | 636-648 | protein | denotes | CC chemokine |
| T14 | 656-665 | protein | denotes | eotaxin-3 |
| T15 | 681-687 | protein | denotes | MPIF-2 |
| T16 | 688-697 | protein | denotes | eotaxin-2 |
| T17 | 699-705 | protein | denotes | SCYA24 |
| T18 | 711-720 | protein | denotes | eotaxin-3 |
| T19 | 722-728 | protein | denotes | SCYA26 |
| T20 | 818-827 | protein | denotes | eotaxin-3 |
| T21 | 916-925 | protein | denotes | eotaxin-3 |
| T22 | 962-971 | protein | denotes | Eotaxin-3 |
| T23 | 1027-1050 | protein | denotes | CC chemokine receptor 3 |
| T24 | 1052-1056 | protein | denotes | CCR3 |
| T25 | 1104-1113 | protein | denotes | Eotaxin-3 |
| T26 | 1156-1160 | protein | denotes | CCR3 |
| T27 | 1208-1217 | protein | denotes | Eotaxin-3 |
| T28 | 1326-1335 | protein | denotes | eotaxin-3 |
| T29 | 1373-1377 | protein | denotes | CCR3 |
| T30 | 1394-1403 | protein | denotes | eotaxin-3 |
| T31 | 1409-1413 | protein | denotes | CCR3 |
| T32 | 1483-1490 | protein | denotes | eotaxin |
| T33 | 1510-1519 | protein | denotes | eotaxin-3 |
| T34 | 1610-1614 | protein | denotes | CCR3 |
| T35 | 1736-1745 | protein | denotes | chemokine |
AIMed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 49-58 | protein | denotes | Eotaxin-3 |
| T2 | 91-114 | protein | denotes | CC chemokine receptor 3 |
| T3 | 161-199 | protein | denotes | myeloid progenitor inhibitory factor 2 |
| T4 | 201-207 | protein | denotes | MPIF-2 |
| T5 | 209-218 | protein | denotes | eotaxin-2 |
| T6 | 582-588 | protein | denotes | MPIF-2 |
| T7 | 589-598 | protein | denotes | eotaxin-2 |
| T8 | 600-606 | protein | denotes | SCYA24 |
| T9 | 656-665 | protein | denotes | eotaxin-3 |
| T10 | 681-687 | protein | denotes | MPIF-2 |
| T11 | 688-697 | protein | denotes | eotaxin-2 |
| T12 | 699-705 | protein | denotes | SCYA24 |
| T13 | 711-720 | protein | denotes | eotaxin-3 |
| T14 | 722-728 | protein | denotes | SCYA26 |
| T15 | 818-827 | protein | denotes | eotaxin-3 |
| T16 | 916-925 | protein | denotes | eotaxin-3 |
| T17 | 962-971 | protein | denotes | Eotaxin-3 |
| T18 | 1027-1050 | protein | denotes | CC chemokine receptor 3 |
| T19 | 1052-1056 | protein | denotes | CCR3 |
| T20 | 1104-1113 | protein | denotes | Eotaxin-3 |
| T21 | 1143-1152 | protein | denotes | I-eotaxin |
| T22 | 1156-1160 | protein | denotes | CCR3 |
| T23 | 1208-1217 | protein | denotes | Eotaxin-3 |
| T24 | 1326-1335 | protein | denotes | eotaxin-3 |
| T25 | 1373-1377 | protein | denotes | CCR3 |
| T26 | 1394-1403 | protein | denotes | eotaxin-3 |
| T27 | 1409-1413 | protein | denotes | CCR3 |
| T28 | 1483-1490 | protein | denotes | eotaxin |
| T29 | 1510-1519 | protein | denotes | eotaxin-3 |
| T30 | 1610-1614 | protein | denotes | CCR3 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 29-34 | OrganismTaxon | denotes | human | 9606 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 869-874 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/MAT_0000036 |
| T2 | 1256-1261 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 222-232 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T2 | 869-874 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948|http://purl.obolibrary.org/obo/UBERON_0007100|http://purl.obolibrary.org/obo/UBERON_0015228|http://purl.obolibrary.org/obo/UBERON_0015230 |
| T6 | 879-884 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T7 | 1256-1261 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T8 | 1262-1273 | Body_part | denotes | eosinophils | http://purl.obolibrary.org/obo/CL_0017502 |
| T9 | 1577-1587 | Body_part | denotes | eosinophil | http://purl.obolibrary.org/obo/CL_0017502 |