PubMed:10488118 / 979-1322 JSONTXT

{"project":"sentences","denotations":[{"id":"T7","span":{"begin":0,"end":343},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T8","span":{"begin":292,"end":296},"obj":"http://purl.obolibrary.org/obo/MAT_0000299"},{"id":"T9","span":{"begin":313,"end":317},"obj":"http://purl.obolibrary.org/obo/MAT_0000299"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":153,"end":166},"obj":"HP_0003072"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"10488118-6#60#68#gene5641","span":{"begin":60,"end":68},"obj":"gene5641"},{"id":"10488118-6#153#166#diseaseC0020437","span":{"begin":153,"end":166},"obj":"diseaseC0020437"}],"relations":[{"id":"60#68#gene5641153#166#diseaseC0020437","pred":"associated_with","subj":"10488118-6#60#68#gene5641","obj":"10488118-6#153#166#diseaseC0020437"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":60,"end":68},"obj":"gene:5641"},{"id":"T1","span":{"begin":153,"end":166},"obj":"disease:C0020437"},{"id":"T2","span":{"begin":178,"end":183},"obj":"gene:5744"},{"id":"T3","span":{"begin":153,"end":166},"obj":"disease:C0020437"},{"id":"T4","span":{"begin":337,"end":342},"obj":"gene:5744"},{"id":"T5","span":{"begin":153,"end":166},"obj":"disease:C0020437"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"Anatomy-MAT","denotations":[{"id":"T7","span":{"begin":292,"end":296},"obj":"Body_part"},{"id":"T8","span":{"begin":313,"end":317},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"mat_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MAT_0000299"},{"id":"A8","pred":"mat_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MAT_0000299"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"mondo_disease","denotations":[{"id":"T1","span":{"begin":153,"end":166},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0001566"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"NCBITAXON","denotations":[{"id":"T12","span":{"begin":21,"end":25},"obj":"OrganismTaxon"}],"attributes":[{"id":"A12","pred":"db_id","subj":"T12","obj":"10088"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T19","span":{"begin":242,"end":245},"obj":"Body_part"},{"id":"T20","span":{"begin":261,"end":264},"obj":"Body_part"},{"id":"T21","span":{"begin":292,"end":296},"obj":"Body_part"},{"id":"T23","span":{"begin":313,"end":325},"obj":"Body_part"}],"attributes":[{"id":"A19","pred":"uberon_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CL_0000092"},{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CL_0000092"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0001474"},{"id":"A22","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0002481"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_4200230"}],"text":"Implantation in nude mice of 293 cells transfected with the legumain cDNA and constitutively expressing high levels of the protein significantly reduced hypercalcemia induced by PTHrP by about 50%, and significantly inhibited the increase in OCL surface and in OCL number expressed per mm(2) bone area and per mm bone surface induced by PTHrP."}