PubMed:10487715 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10487715","sourcedb":"PubMed","sourceid":"10487715","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10487715","text":"Increased IkappaB expression and diminished nuclear NF-kappaB in human mononuclear cells following hydrocortisone injection.\nWe have recently demonstrated that hydrocortisone and other glucocorticoids inhibit reactive oxygen species (ROS) generation by mononuclear (MNC) and polymorphonuclear leucocytes (PMNL). Since NF-kappaB/IkappaB system regulates the transcription of proinflammatory genes, including those responsible for ROS generation, we tested the hypothesis that hydrocortisone may stimulate IkappaB production thus inhibiting NF-kappaB translocation from the cytosol into the nucleus in MNC, in vivo. One hundred milligram of hydrocortisone was injected intravenously into 4 normal subjects. Blood samples were obtained prior to the injection and at 1, 2, 4, 8 and 24 hr after the injection. Nuclear extracts and total cell lysates were prepared from MNC by standard techniques. IkappaB levels in MNC homogenates increased at 1 hr, peaked at 2-4 hr, started to decrease at 8 hr, and returned to baseline levels at 24 hr. NF-kappaB in MNC nuclear extracts decreased at 1 hr, reached a nadir at 4 hr, gradually increased at 8 hr and returned back to baseline levels at 24 hr. The total protein content of NF-kappaB subunit (P65) in MNC lysates also showed a decrease following hydrocortisone injection. This decrease was observed at 2 hr, reached a nadir at 4 hr, and returned to baseline levels at 24 hr. ROS generation inhibition paralleled NF-kappaB levels in the nucleus. It was inhibited at 1 hr, reached a nadir at 2-4 hr, started to increase at 8 hr, and returned to basal levels at 24 hr. Our data demonstrate that hydrocortisone induces IkappaB and suppresses NF-kappaB expression in MNC in parallel. IkappaB further reduces the translocation of NF-kappaB into the nucleus thus preventing the expression of proinflammatory genes.","tracks":[{"project":"genia-medco-coref","denotations":[{"id":"C36","span":{"begin":99,"end":123},"obj":"NP"},{"id":"C9","span":{"begin":160,"end":174},"obj":"NP"},{"id":"C2","span":{"begin":209,"end":249},"obj":"NP"},{"id":"C14","span":{"begin":253,"end":270},"obj":"NP"},{"id":"C3","span":{"begin":429,"end":443},"obj":"NP"},{"id":"C34","span":{"begin":455,"end":469},"obj":"NP"},{"id":"C35","span":{"begin":470,"end":474},"obj":"NP"},{"id":"C7","span":{"begin":475,"end":489},"obj":"NP"},{"id":"C31","span":{"begin":600,"end":603},"obj":"NP"},{"id":"C22","span":{"begin":639,"end":653},"obj":"NP"},{"id":"C37","span":{"begin":742,"end":755},"obj":"NP"},{"id":"C38","span":{"begin":790,"end":803},"obj":"NP"},{"id":"C32","span":{"begin":805,"end":821},"obj":"NP"},{"id":"C13","span":{"begin":864,"end":867},"obj":"NP"},{"id":"C33","span":{"begin":1047,"end":1067},"obj":"NP"},{"id":"C21","span":{"begin":1288,"end":1312},"obj":"NP"},{"id":"C39","span":{"begin":1267,"end":1312},"obj":"NP"},{"id":"C40","span":{"begin":1314,"end":1327},"obj":"NP"},{"id":"C42","span":{"begin":1474,"end":1485},"obj":"NP"},{"id":"C25","span":{"begin":1634,"end":1648},"obj":"NP"},{"id":"C26","span":{"begin":1657,"end":1664},"obj":"NP"},{"id":"C28","span":{"begin":1704,"end":1707},"obj":"NP"},{"id":"C29","span":{"begin":1721,"end":1728},"obj":"NP"},{"id":"C43","span":{"begin":1781,"end":1792},"obj":"NP"}],"relations":[{"id":"R1","pred":"coref-ident","subj":"C3","obj":"C2"},{"id":"R2","pred":"coref-relat","subj":"C35","obj":"C34"},{"id":"R3","pred":"coref-ident","subj":"C7","obj":"C9"},{"id":"R4","pred":"coref-ident","subj":"C31","obj":"C14"},{"id":"R5","pred":"coref-ident","subj":"C22","obj":"C7"},{"id":"R6","pred":"coref-ident","subj":"C37","obj":"C36"},{"id":"R7","pred":"coref-ident","subj":"C38","obj":"C37"},{"id":"R8","pred":"coref-ident","subj":"C13","obj":"C31"},{"id":"R9","pred":"coref-ident","subj":"C33","obj":"C32"},{"id":"R10","pred":"coref-ident","subj":"C21","obj":"C38"},{"id":"R11","pred":"coref-ident","subj":"C40","obj":"C39"},{"id":"R12","pred":"coref-ident","subj":"C25","obj":"C7"},{"id":"R13","pred":"coref-ident","subj":"C28","obj":"C13"},{"id":"R14","pred":"coref-ident","subj":"C29","obj":"C26"},{"id":"R15","pred":"coref-ident","subj":"C43","obj":"C42"}],"attributes":[{"subj":"C36","pred":"source","obj":"genia-medco-coref"},{"subj":"C9","pred":"source","obj":"genia-medco-coref"},{"subj":"C2","pred":"source","obj":"genia-medco-coref"},{"subj":"C14","pred":"source","obj":"genia-medco-coref"},{"subj":"C3","pred":"source","obj":"genia-medco-coref"},{"subj":"C34","pred":"source","obj":"genia-medco-coref"},{"subj":"C35","pred":"source","obj":"genia-medco-coref"},{"subj":"C7","pred":"source","obj":"genia-medco-coref"},{"subj":"C31","pred":"source","obj":"genia-medco-coref"},{"subj":"C22","pred":"source","obj":"genia-medco-coref"},{"subj":"C37","pred":"source","obj":"genia-medco-coref"},{"subj":"C38","pred":"source","obj":"genia-medco-coref"},{"subj":"C32","pred":"source","obj":"genia-medco-coref"},{"subj":"C13","pred":"source","obj":"genia-medco-coref"},{"subj":"C33","pred":"source","obj":"genia-medco-coref"},{"subj":"C21","pred":"source","obj":"genia-medco-coref"},{"subj":"C39","pred":"source","obj":"genia-medco-coref"},{"subj":"C40","pred":"source","obj":"genia-medco-coref"},{"subj":"C42","pred":"source","obj":"genia-medco-coref"},{"subj":"C25","pred":"source","obj":"genia-medco-coref"},{"subj":"C26","pred":"source","obj":"genia-medco-coref"},{"subj":"C28","pred":"source","obj":"genia-medco-coref"},{"subj":"C29","pred":"source","obj":"genia-medco-coref"},{"subj":"C43","pred":"source","obj":"genia-medco-coref"}]},{"project":"metamap-sample","denotations":[{"id":"T1","span":{"begin":66,"end":70},"obj":"C0086418"},{"id":"T2","span":{"begin":1635,"end":1649},"obj":"C0020268"},{"id":"T3","span":{"begin":1289,"end":1302},"obj":"C0020268"},{"id":"T4","span":{"begin":640,"end":654},"obj":"C0020268"},{"id":"T5","span":{"begin":476,"end":490},"obj":"C0020268"},{"id":"T6","span":{"begin":161,"end":175},"obj":"C0020268"},{"id":"T7","span":{"begin":100,"end":114},"obj":"C0020268"},{"id":"T8","span":{"begin":1722,"end":1729},"obj":"C0126732"},{"id":"T9","span":{"begin":1658,"end":1665},"obj":"C0126732"},{"id":"T10","span":{"begin":893,"end":900},"obj":"C0126732"},{"id":"T11","span":{"begin":11,"end":18},"obj":"C0126732"},{"id":"T12","span":{"begin":1767,"end":1776},"obj":"C0079904"},{"id":"T13","span":{"begin":1681,"end":1689},"obj":"C0079904"},{"id":"T14","span":{"begin":1455,"end":1464},"obj":"C0079904"},{"id":"T15","span":{"begin":1217,"end":1225},"obj":"C0079904"},{"id":"T16","span":{"begin":1035,"end":1044},"obj":"C0079904"},{"id":"T17","span":{"begin":53,"end":62},"obj":"C0079904"},{"id":"T18","span":{"begin":1279,"end":1288},"obj":"C0332282"},{"id":"T19","span":{"begin":90,"end":99},"obj":"C0332282"},{"id":"T20","span":{"begin":1123,"end":1132},"obj":"C0205217"},{"id":"T21","span":{"begin":927,"end":936},"obj":"C0205217"},{"id":"T22","span":{"begin":1,"end":10},"obj":"C0205217"},{"id":"T23","span":{"begin":1069,"end":1078},"obj":"C0205216"},{"id":"T24","span":{"begin":34,"end":44},"obj":"C0205216"},{"id":"T25","span":{"begin":1691,"end":1701},"obj":"C0185117"},{"id":"T26","span":{"begin":19,"end":29},"obj":"C0185117"},{"id":"T27","span":{"begin":1304,"end":1313},"obj":"C0021485"},{"id":"T28","span":{"begin":115,"end":124},"obj":"C0021485"},{"id":"T29","span":{"begin":1705,"end":1708},"obj":"C1513475"},{"id":"T30","span":{"begin":1244,"end":1247},"obj":"C1513475"},{"id":"T31","span":{"begin":1048,"end":1051},"obj":"C1513475"},{"id":"T32","span":{"begin":911,"end":914},"obj":"C1513475"},{"id":"T33","span":{"begin":865,"end":868},"obj":"C1513475"},{"id":"T34","span":{"begin":601,"end":604},"obj":"C1513475"},{"id":"T35","span":{"begin":254,"end":265},"obj":"C1513475"},{"id":"T36","span":{"begin":72,"end":83},"obj":"C1513475"},{"id":"T37","span":{"begin":72,"end":89},"obj":"C0806987"},{"id":"T38","span":{"begin":45,"end":52},"obj":"C0521447"},{"id":"T39","span":{"begin":1786,"end":1793},"obj":"C0007610"},{"id":"T40","span":{"begin":1479,"end":1486},"obj":"C0007610"},{"id":"T41","span":{"begin":590,"end":597},"obj":"C0007610"},{"id":"T42","span":{"begin":1422,"end":1432},"obj":"C0079411"},{"id":"T43","span":{"begin":434,"end":444},"obj":"C0079411"},{"id":"T44","span":{"begin":240,"end":250},"obj":"C0079411"},{"id":"T45","span":{"begin":1750,"end":1763},"obj":"C0040715"},{"id":"T46","span":{"begin":550,"end":563},"obj":"C0040715"},{"id":"T47","span":{"begin":1418,"end":1421},"obj":"C0162772"},{"id":"T48","span":{"begin":430,"end":432},"obj":"C0162772"},{"id":"T49","span":{"begin":210,"end":233},"obj":"C0162772"},{"id":"T50","span":{"begin":1592,"end":1598},"obj":"C0441889"},{"id":"T51","span":{"begin":1465,"end":1471},"obj":"C0441889"},{"id":"T52","span":{"begin":1401,"end":1407},"obj":"C0441889"},{"id":"T53","span":{"begin":1171,"end":1177},"obj":"C0441889"},{"id":"T54","span":{"begin":186,"end":200},"obj":"C0017710"},{"id":"T55","span":{"begin":276,"end":304},"obj":"C0027950"},{"id":"T56","span":{"begin":573,"end":580},"obj":"C1383501"},{"id":"T57","span":{"begin":1574,"end":1585},"obj":"C0332156"},{"id":"T58","span":{"begin":1380,"end":1391},"obj":"C0332156"},{"id":"T59","span":{"begin":1145,"end":1153},"obj":"C0332156"},{"id":"T60","span":{"begin":997,"end":1008},"obj":"C0332156"},{"id":"T61","span":{"begin":1505,"end":1509},"obj":"C1412113"},{"id":"T62","span":{"begin":1079,"end":1083},"obj":"C1412113"},{"id":"T63","span":{"begin":937,"end":941},"obj":"C1412113"},{"id":"T64","span":{"begin":761,"end":765},"obj":"C1412113"},{"id":"T65","span":{"begin":529,"end":539},"obj":"C3463820"},{"id":"T66","span":{"begin":1514,"end":1521},"obj":"C2584321"},{"id":"T67","span":{"begin":1351,"end":1358},"obj":"C2584321"},{"id":"T68","span":{"begin":1088,"end":1095},"obj":"C2584321"},{"id":"T69","span":{"begin":1320,"end":1328},"obj":"C0392756"},{"id":"T70","span":{"begin":1270,"end":1278},"obj":"C0392756"},{"id":"T71","span":{"begin":975,"end":983},"obj":"C0392756"},{"id":"T72","span":{"begin":1524,"end":1529},"obj":"C1708760"},{"id":"T73","span":{"begin":1361,"end":1366},"obj":"C1708760"},{"id":"T74","span":{"begin":1098,"end":1103},"obj":"C1708760"},{"id":"T75","span":{"begin":1392,"end":1400},"obj":"C1442488"},{"id":"T76","span":{"begin":1162,"end":1170},"obj":"C1442488"},{"id":"T77","span":{"begin":1009,"end":1017},"obj":"C1442488"},{"id":"T78","span":{"begin":1541,"end":1548},"obj":"C1272689"},{"id":"T79","span":{"begin":964,"end":971},"obj":"C1272689"},{"id":"T80","span":{"begin":1549,"end":1551},"obj":"C1883351"},{"id":"T81","span":{"begin":972,"end":974},"obj":"C1883351"},{"id":"T82","span":{"begin":202,"end":209},"obj":"C0018790"},{"id":"T83","span":{"begin":881,"end":891},"obj":"C0025664"},{"id":"T84","span":{"begin":1248,"end":1255},"obj":"C1881488"},{"id":"T85","span":{"begin":833,"end":845},"obj":"C1881488"},{"id":"T86","span":{"begin":1052,"end":1067},"obj":"C1518434"},{"id":"T87","span":{"begin":806,"end":822},"obj":"C1518434"},{"id":"T88","span":{"begin":1712,"end":1720},"obj":"C2348042"},{"id":"T89","span":{"begin":1444,"end":1453},"obj":"C2348042"},{"id":"T90","span":{"begin":1342,"end":1344},"obj":"C1516077"},{"id":"T91","span":{"begin":953,"end":955},"obj":"C1516077"},{"id":"T92","span":{"begin":1192,"end":1197},"obj":"C0439810"},{"id":"T93","span":{"begin":827,"end":832},"obj":"C0439810"},{"id":"T94","span":{"begin":767,"end":768},"obj":"C2981700"},{"id":"T95","span":{"begin":706,"end":719},"obj":"C0178913"},{"id":"T96","span":{"begin":1613,"end":1617},"obj":"C1511726"},{"id":"T97","span":{"begin":460,"end":470},"obj":"C1512571"},{"id":"T98","span":{"begin":398,"end":407},"obj":"C0332257"},{"id":"T99","span":{"begin":1650,"end":1657},"obj":"C0205263"},{"id":"T100","span":{"begin":1495,"end":1504},"obj":"C0311403"},{"id":"T101","span":{"begin":1333,"end":1341},"obj":"C1441672"},{"id":"T102","span":{"begin":946,"end":952},"obj":"C0444505"},{"id":"T103","span":{"begin":134,"end":142},"obj":"C0332185"},{"id":"T104","span":{"begin":1236,"end":1239},"obj":"C3540646"},{"id":"T105","span":{"begin":1670,"end":1680},"obj":"C1260953"},{"id":"T106","span":{"begin":449,"end":455},"obj":"C0392366"},{"id":"T107","span":{"begin":659,"end":666},"obj":"C1720154"},{"id":"T108","span":{"begin":1799,"end":1809},"obj":"C0309872"},{"id":"T109","span":{"begin":1261,"end":1267},"obj":"C1547282"},{"id":"T110","span":{"begin":513,"end":523},"obj":"C0033268"},{"id":"T111","span":{"begin":337,"end":343},"obj":"C0449913"},{"id":"T112","span":{"begin":734,"end":742},"obj":"C0332152"},{"id":"T113","span":{"begin":1433,"end":1443},"obj":"C0021469"},{"id":"T114","span":{"begin":1586,"end":1591},"obj":"C0205112"},{"id":"T115","span":{"begin":1154,"end":1158},"obj":"C0205095"},{"id":"T116","span":{"begin":1552,"end":1560},"obj":"C0442805"},{"id":"T117","span":{"begin":725,"end":733},"obj":"C1301820"},{"id":"T118","span":{"begin":689,"end":695},"obj":"C0439166"},{"id":"T119","span":{"begin":627,"end":636},"obj":"C0439210"},{"id":"T120","span":{"begin":851,"end":859},"obj":"C1521827"},{"id":"T121","span":{"begin":414,"end":425},"obj":"C1273518"},{"id":"T122","span":{"begin":1206,"end":1213},"obj":"C0456205"},{"id":"T123","span":{"begin":696,"end":704},"obj":"C1706203"},{"id":"T124","span":{"begin":1730,"end":1737},"obj":"C1517331"},{"id":"T125","span":{"begin":872,"end":880},"obj":"C1442989"},{"id":"T126","span":{"begin":1192,"end":1205},"obj":"C0555903"},{"id":"T127","span":{"begin":615,"end":618},"obj":"C0205447"},{"id":"T128","span":{"begin":1227,"end":1234},"obj":"C1711351"}],"attributes":[{"subj":"T1","pred":"source","obj":"metamap-sample"},{"subj":"T2","pred":"source","obj":"metamap-sample"},{"subj":"T3","pred":"source","obj":"metamap-sample"},{"subj":"T4","pred":"source","obj":"metamap-sample"},{"subj":"T5","pred":"source","obj":"metamap-sample"},{"subj":"T6","pred":"source","obj":"metamap-sample"},{"subj":"T7","pred":"source","obj":"metamap-sample"},{"subj":"T8","pred":"source","obj":"metamap-sample"},{"subj":"T9","pred":"source","obj":"metamap-sample"},{"subj":"T10","pred":"source","obj":"metamap-sample"},{"subj":"T11","pred":"source","obj":"metamap-sample"},{"subj":"T12","pred":"source","obj":"metamap-sample"},{"subj":"T13","pred":"source","obj":"metamap-sample"},{"subj":"T14","pred":"source","obj":"metamap-sample"},{"subj":"T15","pred":"source","obj":"metamap-sample"},{"subj":"T16","pred":"source","obj":"metamap-sample"},{"subj":"T17","pred":"source","obj":"metamap-sample"},{"subj":"T18","pred":"source","obj":"metamap-sample"},{"subj":"T19","pred":"source","obj":"metamap-sample"},{"subj":"T20","pred":"source","obj":"metamap-sample"},{"subj":"T21","pred":"source","obj":"metamap-sample"},{"subj":"T22","pred":"source","obj":"metamap-sample"},{"subj":"T23","pred":"source","obj":"metamap-sample"},{"subj":"T24","pred":"source","obj":"metamap-sample"},{"subj":"T25","pred":"source","obj":"metamap-sample"},{"subj":"T26","pred":"source","obj":"metamap-sample"},{"subj":"T27","pred":"source","obj":"metamap-sample"},{"subj":"T28","pred":"source","obj":"metamap-sample"},{"subj":"T29","pred":"source","obj":"metamap-sample"},{"subj":"T30","pred":"source","obj":"metamap-sample"},{"subj":"T31","pred":"source","obj":"metamap-sample"},{"subj":"T32","pred":"source","obj":"metamap-sample"},{"subj":"T33","pred":"source","obj":"metamap-sample"},{"subj":"T34","pred":"source","obj":"metamap-sample"},{"subj":"T35","pred":"source","obj":"metamap-sample"},{"subj":"T36","pred":"source","obj":"metamap-sample"},{"subj":"T37","pred":"source","obj":"metamap-sample"},{"subj":"T38","pred":"source","obj":"metamap-sample"},{"subj":"T39","pred":"source","obj":"metamap-sample"},{"subj":"T40","pred":"source","obj":"metamap-sample"},{"subj":"T41","pred":"source","obj":"metamap-sample"},{"subj":"T42","pred":"source","obj":"metamap-sample"},{"subj":"T43","pred":"source","obj":"metamap-sample"},{"subj":"T44","pred":"source","obj":"metamap-sample"},{"subj":"T45","pred":"source","obj":"metamap-sample"},{"subj":"T46","pred":"source","obj":"metamap-sample"},{"subj":"T47","pred":"source","obj":"metamap-sample"},{"subj":"T48","pred":"source","obj":"metamap-sample"},{"subj":"T49","pred":"source","obj":"metamap-sample"},{"subj":"T50","pred":"source","obj":"metamap-sample"},{"subj":"T51","pred":"source","obj":"metamap-sample"},{"subj":"T52","pred":"source","obj":"metamap-sample"},{"subj":"T53","pred":"source","obj":"metamap-sample"},{"subj":"T54","pred":"source","obj":"metamap-sample"},{"subj":"T55","pred":"source","obj":"metamap-sample"},{"subj":"T56","pred":"source","obj":"metamap-sample"},{"subj":"T57","pred":"source","obj":"metamap-sample"},{"subj":"T58","pred":"source","obj":"metamap-sample"},{"subj":"T59","pred":"source","obj":"metamap-sample"},{"subj":"T60","pred":"source","obj":"metamap-sample"},{"subj":"T61","pred":"source","obj":"metamap-sample"},{"subj":"T62","pred":"source","obj":"metamap-sample"},{"subj":"T63","pred":"source","obj":"metamap-sample"},{"subj":"T64","pred":"source","obj":"metamap-sample"},{"subj":"T65","pred":"source","obj":"metamap-sample"},{"subj":"T66","pred":"source","obj":"metamap-sample"},{"subj":"T67","pred":"source","obj":"metamap-sample"},{"subj":"T68","pred":"source","obj":"metamap-sample"},{"subj":"T69","pred":"source","obj":"metamap-sample"},{"subj":"T70","pred":"source","obj":"metamap-sample"},{"subj":"T71","pred":"source","obj":"metamap-sample"},{"subj":"T72","pred":"source","obj":"metamap-sample"},{"subj":"T73","pred":"source","obj":"metamap-sample"},{"subj":"T74","pred":"source","obj":"metamap-sample"},{"subj":"T75","pred":"source","obj":"metamap-sample"},{"subj":"T76","pred":"source","obj":"metamap-sample"},{"subj":"T77","pred":"source","obj":"metamap-sample"},{"subj":"T78","pred":"source","obj":"metamap-sample"},{"subj":"T79","pred":"source","obj":"metamap-sample"},{"subj":"T80","pred":"source","obj":"metamap-sample"},{"subj":"T81","pred":"source","obj":"metamap-sample"},{"subj":"T82","pred":"source","obj":"metamap-sample"},{"subj":"T83","pred":"source","obj":"metamap-sample"},{"subj":"T84","pred":"source","obj":"metamap-sample"},{"subj":"T85","pred":"source","obj":"metamap-sample"},{"subj":"T86","pred":"source","obj":"metamap-sample"},{"subj":"T87","pred":"source","obj":"metamap-sample"},{"subj":"T88","pred":"source","obj":"metamap-sample"},{"subj":"T89","pred":"source","obj":"metamap-sample"},{"subj":"T90","pred":"source","obj":"metamap-sample"},{"subj":"T91","pred":"source","obj":"metamap-sample"},{"subj":"T92","pred":"source","obj":"metamap-sample"},{"subj":"T93","pred":"source","obj":"metamap-sample"},{"subj":"T94","pred":"source","obj":"metamap-sample"},{"subj":"T95","pred":"source","obj":"metamap-sample"},{"subj":"T96","pred":"source","obj":"metamap-sample"},{"subj":"T97","pred":"source","obj":"metamap-sample"},{"subj":"T98","pred":"source","obj":"metamap-sample"},{"subj":"T99","pred":"source","obj":"metamap-sample"},{"subj":"T100","pred":"source","obj":"metamap-sample"},{"subj":"T101","pred":"source","obj":"metamap-sample"},{"subj":"T102","pred":"source","obj":"metamap-sample"},{"subj":"T103","pred":"source","obj":"metamap-sample"},{"subj":"T104","pred":"source","obj":"metamap-sample"},{"subj":"T105","pred":"source","obj":"metamap-sample"},{"subj":"T106","pred":"source","obj":"metamap-sample"},{"subj":"T107","pred":"source","obj":"metamap-sample"},{"subj":"T108","pred":"source","obj":"metamap-sample"},{"subj":"T109","pred":"source","obj":"metamap-sample"},{"subj":"T110","pred":"source","obj":"metamap-sample"},{"subj":"T111","pred":"source","obj":"metamap-sample"},{"subj":"T112","pred":"source","obj":"metamap-sample"},{"subj":"T113","pred":"source","obj":"metamap-sample"},{"subj":"T114","pred":"source","obj":"metamap-sample"},{"subj":"T115","pred":"source","obj":"metamap-sample"},{"subj":"T116","pred":"source","obj":"metamap-sample"},{"subj":"T117","pred":"source","obj":"metamap-sample"},{"subj":"T118","pred":"source","obj":"metamap-sample"},{"subj":"T119","pred":"source","obj":"metamap-sample"},{"subj":"T120","pred":"source","obj":"metamap-sample"},{"subj":"T121","pred":"source","obj":"metamap-sample"},{"subj":"T122","pred":"source","obj":"metamap-sample"},{"subj":"T123","pred":"source","obj":"metamap-sample"},{"subj":"T124","pred":"source","obj":"metamap-sample"},{"subj":"T125","pred":"source","obj":"metamap-sample"},{"subj":"T126","pred":"source","obj":"metamap-sample"},{"subj":"T127","pred":"source","obj":"metamap-sample"},{"subj":"T128","pred":"source","obj":"metamap-sample"}]},{"project":"semrep-sample","denotations":[{"id":"E1-ti-1","span":{"begin":0,"end":9},"obj":"cui:C0205217"},{"id":"E2-ti-1","span":{"begin":10,"end":17},"obj":"cui:C0126732"},{"id":"E3-ti-1","span":{"begin":18,"end":28},"obj":"cui:C0185117"},{"id":"E4-ti-1","span":{"begin":33,"end":43},"obj":"cui:C0205216"},{"id":"E5-ti-1","span":{"begin":44,"end":51},"obj":"cui:C0521447"},{"id":"E6-ti-1","span":{"begin":52,"end":61},"obj":"cui:C0079904"},{"id":"E7-ti-1","span":{"begin":65,"end":70},"obj":"cui:C0020114"},{"id":"E8-ti-1","span":{"begin":71,"end":88},"obj":"cui:C0806987"},{"id":"E9-ti-1","span":{"begin":99,"end":113},"obj":"cui:C0020268"},{"id":"E10-ti-1","span":{"begin":114,"end":123},"obj":"cui:C1533685"},{"id":"T1","span":{"begin":99,"end":123},"obj":"ISA"},{"id":"T2","span":{"begin":65,"end":88},"obj":"PART_OF"},{"id":"T3","span":{"begin":62,"end":64},"obj":"LOCATION_OF"},{"id":"T4","span":{"begin":62,"end":64},"obj":"LOCATION_OF"},{"id":"T5","span":{"begin":99,"end":123},"obj":"USES"},{"id":"T6","span":{"begin":99,"end":123},"obj":"USES"},{"id":"E1-ab-1","span":{"begin":133,"end":141},"obj":"cui:C0332185"},{"id":"E2-ab-1","span":{"begin":160,"end":174},"obj":"cui:C0020268"},{"id":"E3-ab-1","span":{"begin":185,"end":200},"obj":"cui:C0017710"},{"id":"E4-ab-1","span":{"begin":209,"end":232},"obj":"cui:C0162772"},{"id":"E5-ab-1","span":{"begin":239,"end":249},"obj":"cui:C0079411"},{"id":"E6-ab-1","span":{"begin":253,"end":264},"obj":"cui:C1513475"},{"id":"E7-ab-1","span":{"begin":275,"end":303},"obj":"cui:C0027950"},{"id":"T7","span":{"begin":160,"end":200},"obj":"ISA"},{"id":"T8","span":{"begin":160,"end":200},"obj":"ISA"},{"id":"T9","span":{"begin":201,"end":208},"obj":"INHIBITS"},{"id":"T10","span":{"begin":201,"end":208},"obj":"INHIBITS"},{"id":"T11","span":{"begin":160,"end":200},"obj":"INHIBITS"},{"id":"T12","span":{"begin":160,"end":200},"obj":"INHIBITS"},{"id":"E1-ab-2","span":{"begin":318,"end":327},"obj":"cui:C0079904"},{"id":"E2-ab-2","span":{"begin":328,"end":335},"obj":"cui:C0126732"},{"id":"E3-ab-2","span":{"begin":336,"end":342},"obj":"cui:C0449913"},{"id":"E4-ab-2","span":{"begin":357,"end":370},"obj":"cui:C0040649"},{"id":"E5-ab-2","span":{"begin":390,"end":395},"obj":"cui:C0017337"},{"id":"E6-ab-2","span":{"begin":429,"end":432},"obj":"cui:C0162772"},{"id":"E7-ab-2","span":{"begin":433,"end":443},"obj":"cui:C0079411"},{"id":"E8-ab-2","span":{"begin":459,"end":469},"obj":"cui:C1512571"},{"id":"E9-ab-2","span":{"begin":475,"end":489},"obj":"cui:C0020268"},{"id":"E10-ab-2","span":{"begin":504,"end":511},"obj":"cui:C0126732"},{"id":"E11-ab-2","span":{"begin":512,"end":522},"obj":"cui:C0033268"},{"id":"E12-ab-2","span":{"begin":539,"end":548},"obj":"cui:C0079904"},{"id":"E13-ab-2","span":{"begin":572,"end":579},"obj":"cui:C0010854"},{"id":"E14-ab-2","span":{"begin":600,"end":603},"obj":"cui:C1513475"},{"id":"T13","span":{"begin":343,"end":352},"obj":"AFFECTS"},{"id":"T14","span":{"begin":494,"end":503},"obj":"STIMULATES"},{"id":"T15","span":{"begin":563,"end":567},"obj":"LOCATION_OF"},{"id":"E1-ab-3","span":{"begin":614,"end":617},"obj":"cui:C0205447"},{"id":"E2-ab-3","span":{"begin":626,"end":635},"obj":"cui:C0439210"},{"id":"E3-ab-3","span":{"begin":639,"end":653},"obj":"cui:C0020268"},{"id":"E4-ab-3","span":{"begin":688,"end":694},"obj":"cui:C0205307"},{"id":"E5-ab-3","span":{"begin":695,"end":703},"obj":"cui:C1550501"},{"id":"E1-ab-4","span":{"begin":705,"end":718},"obj":"cui:C0178913"},{"id":"E2-ab-4","span":{"begin":746,"end":755},"obj":"cui:C1533685"},{"id":"E3-ab-4","span":{"begin":794,"end":803},"obj":"cui:C1533685"},{"id":"T16","span":{"begin":784,"end":789},"obj":"PRECEDES"},{"id":"E1-ab-5","span":{"begin":805,"end":821},"obj":"cui:C1518434"},{"id":"E2-ab-5","span":{"begin":826,"end":831},"obj":"cui:C0439810"},{"id":"E3-ab-5","span":{"begin":832,"end":836},"obj":"cui:C0007634"},{"id":"E4-ab-5","span":{"begin":864,"end":867},"obj":"cui:C1513475"},{"id":"E1-ab-6","span":{"begin":892,"end":899},"obj":"cui:C0126732"},{"id":"E2-ab-6","span":{"begin":900,"end":906},"obj":"cui:C0441889"},{"id":"E3-ab-6","span":{"begin":910,"end":913},"obj":"cui:C1513475"},{"id":"E4-ab-6","span":{"begin":1008,"end":1016},"obj":"cui:C1442488"},{"id":"E5-ab-6","span":{"begin":1017,"end":1023},"obj":"cui:C0441889"},{"id":"E1-ab-7","span":{"begin":1034,"end":1043},"obj":"cui:C0079904"},{"id":"E2-ab-7","span":{"begin":1047,"end":1050},"obj":"cui:C1513475"},{"id":"E3-ab-7","span":{"begin":1051,"end":1067},"obj":"cui:C1518434"},{"id":"E4-ab-7","span":{"begin":1153,"end":1157},"obj":"cui:C0004600"},{"id":"E5-ab-7","span":{"begin":1161,"end":1169},"obj":"cui:C1442488"},{"id":"E6-ab-7","span":{"begin":1170,"end":1176},"obj":"cui:C0441889"},{"id":"E1-ab-8","span":{"begin":1191,"end":1196},"obj":"cui:C0439810"},{"id":"E2-ab-8","span":{"begin":1197,"end":1204},"obj":"cui:C0033684"},{"id":"E3-ab-8","span":{"begin":1216,"end":1225},"obj":"cui:C0079904"},{"id":"E4-ab-8","span":{"begin":1235,"end":1238},"obj":"cui:C0599933"},{"id":"E5-ab-8","span":{"begin":1243,"end":1246},"obj":"cui:C1513475"},{"id":"E6-ab-8","span":{"begin":1269,"end":1277},"obj":"cui:C0547047"},{"id":"E7-ab-8","span":{"begin":1288,"end":1302},"obj":"cui:C0020268"},{"id":"E8-ab-8","span":{"begin":1303,"end":1312},"obj":"cui:C1533685"},{"id":"T17","span":{"begin":1288,"end":1312},"obj":"ISA"},{"id":"T18","span":{"begin":1288,"end":1312},"obj":"USES"},{"id":"T19","span":{"begin":1288,"end":1312},"obj":"USES"},{"id":"E1-ab-9","span":{"begin":1319,"end":1327},"obj":"cui:C0547047"},{"id":"E2-ab-9","span":{"begin":1391,"end":1399},"obj":"cui:C1442488"},{"id":"E3-ab-9","span":{"begin":1400,"end":1406},"obj":"cui:C0441889"},{"id":"E1-ab-10","span":{"begin":1417,"end":1420},"obj":"cui:C0162772"},{"id":"E2-ab-10","span":{"begin":1421,"end":1431},"obj":"cui:C0079411"},{"id":"E3-ab-10","span":{"begin":1454,"end":1463},"obj":"cui:C0079904"},{"id":"E4-ab-10","span":{"begin":1464,"end":1470},"obj":"cui:C0441889"},{"id":"E1-ab-11","span":{"begin":1585,"end":1590},"obj":"cui:C0205112"},{"id":"E2-ab-11","span":{"begin":1591,"end":1597},"obj":"cui:C0441889"},{"id":"E1-ab-12","span":{"begin":1612,"end":1616},"obj":"cui:C1511726"},{"id":"E2-ab-12","span":{"begin":1634,"end":1648},"obj":"cui:C0020268"},{"id":"E3-ab-12","span":{"begin":1657,"end":1664},"obj":"cui:C0126732"},{"id":"E4-ab-12","span":{"begin":1680,"end":1689},"obj":"cui:C0079904"},{"id":"E5-ab-12","span":{"begin":1690,"end":1700},"obj":"cui:C0185117"},{"id":"E6-ab-12","span":{"begin":1704,"end":1707},"obj":"cui:C1513475"},{"id":"T20","span":{"begin":1649,"end":1656},"obj":"STIMULATES"},{"id":"E1-ab-13","span":{"begin":1721,"end":1728},"obj":"cui:C0126732"},{"id":"E2-ab-13","span":{"begin":1729,"end":1736},"obj":"cui:C1517331"},{"id":"E3-ab-13","span":{"begin":1766,"end":1775},"obj":"cui:C0079904"},{"id":"E4-ab-13","span":{"begin":1813,"end":1823},"obj":"cui:C0185117"},{"id":"E5-ab-13","span":{"begin":1843,"end":1848},"obj":"cui:C0017337"}],"relations":[{"id":"R1","pred":"subjectOf","subj":"E9-ti-1","obj":"T1"},{"id":"R2","pred":"objectOf","subj":"E10-ti-1","obj":"T1"},{"id":"R3","pred":"subjectOf","subj":"E8-ti-1","obj":"T2"},{"id":"R4","pred":"objectOf","subj":"E7-ti-1","obj":"T2"},{"id":"R5","pred":"subjectOf","subj":"E8-ti-1","obj":"T3"},{"id":"R6","pred":"objectOf","subj":"E6-ti-1","obj":"T3"},{"id":"R7","pred":"subjectOf","subj":"E8-ti-1","obj":"T4"},{"id":"R8","pred":"objectOf","subj":"E2-ti-1","obj":"T4"},{"id":"R9","pred":"subjectOf","subj":"E10-ti-1","obj":"T5"},{"id":"R10","pred":"objectOf","subj":"E9-ti-1","obj":"T5"},{"id":"R11","pred":"subjectOf","subj":"E9-ti-1","obj":"T6"},{"id":"R12","pred":"objectOf","subj":"E9-ti-1","obj":"T6"},{"id":"R13","pred":"subjectOf","subj":"E2-ab-1","obj":"T7"},{"id":"R14","pred":"objectOf","subj":"E3-ab-1","obj":"T7"},{"id":"R15","pred":"subjectOf","subj":"E3-ab-1","obj":"T8"},{"id":"R16","pred":"objectOf","subj":"E2-ab-1","obj":"T8"},{"id":"R17","pred":"subjectOf","subj":"E3-ab-1","obj":"T9"},{"id":"R18","pred":"objectOf","subj":"E4-ab-1","obj":"T9"},{"id":"R19","pred":"subjectOf","subj":"E2-ab-1","obj":"T10"},{"id":"R20","pred":"objectOf","subj":"E4-ab-1","obj":"T10"},{"id":"R21","pred":"subjectOf","subj":"E2-ab-1","obj":"T11"},{"id":"R22","pred":"objectOf","subj":"E4-ab-1","obj":"T11"},{"id":"R23","pred":"subjectOf","subj":"E3-ab-1","obj":"T12"},{"id":"R24","pred":"objectOf","subj":"E4-ab-1","obj":"T12"},{"id":"R25","pred":"subjectOf","subj":"E2-ab-2","obj":"T13"},{"id":"R26","pred":"objectOf","subj":"E4-ab-2","obj":"T13"},{"id":"R27","pred":"subjectOf","subj":"E9-ab-2","obj":"T14"},{"id":"R28","pred":"objectOf","subj":"E10-ab-2","obj":"T14"},{"id":"R29","pred":"subjectOf","subj":"E13-ab-2","obj":"T15"},{"id":"R30","pred":"objectOf","subj":"E6-ab-2","obj":"T15"},{"id":"R31","pred":"subjectOf","subj":"E3-ab-4","obj":"T16"},{"id":"R32","pred":"objectOf","subj":"E2-ab-4","obj":"T16"},{"id":"R33","pred":"subjectOf","subj":"E7-ab-8","obj":"T17"},{"id":"R34","pred":"objectOf","subj":"E8-ab-8","obj":"T17"},{"id":"R35","pred":"subjectOf","subj":"E8-ab-8","obj":"T18"},{"id":"R36","pred":"objectOf","subj":"E7-ab-8","obj":"T18"},{"id":"R37","pred":"subjectOf","subj":"E7-ab-8","obj":"T19"},{"id":"R38","pred":"objectOf","subj":"E7-ab-8","obj":"T19"},{"id":"R39","pred":"subjectOf","subj":"E2-ab-12","obj":"T20"},{"id":"R40","pred":"objectOf","subj":"E3-ab-12","obj":"T20"}],"attributes":[{"subj":"E1-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E2-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E3-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E4-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E5-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E6-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E7-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E8-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E9-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E10-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"T1","pred":"source","obj":"semrep-sample"},{"subj":"T2","pred":"source","obj":"semrep-sample"},{"subj":"T3","pred":"source","obj":"semrep-sample"},{"subj":"T4","pred":"source","obj":"semrep-sample"},{"subj":"T5","pred":"source","obj":"semrep-sample"},{"subj":"T6","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"T7","pred":"source","obj":"semrep-sample"},{"subj":"T8","pred":"source","obj":"semrep-sample"},{"subj":"T9","pred":"source","obj":"semrep-sample"},{"subj":"T10","pred":"source","obj":"semrep-sample"},{"subj":"T11","pred":"source","obj":"semrep-sample"},{"subj":"T12","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E10-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E11-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E12-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E13-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E14-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"T13","pred":"source","obj":"semrep-sample"},{"subj":"T14","pred":"source","obj":"semrep-sample"},{"subj":"T15","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"T16","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"T17","pred":"source","obj":"semrep-sample"},{"subj":"T18","pred":"source","obj":"semrep-sample"},{"subj":"T19","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-11","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-11","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-12","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-12","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-12","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-12","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-12","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-12","pred":"source","obj":"semrep-sample"},{"subj":"T20","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-13","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-13","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-13","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-13","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-13","pred":"source","obj":"semrep-sample"}]},{"project":"jnlpba-st-training","denotations":[{"id":"T1","span":{"begin":10,"end":17},"obj":"protein"},{"id":"T2","span":{"begin":44,"end":61},"obj":"protein"},{"id":"T3","span":{"begin":65,"end":88},"obj":"cell_type"},{"id":"T4","span":{"begin":253,"end":303},"obj":"cell_type"},{"id":"T5","span":{"begin":305,"end":309},"obj":"cell_type"},{"id":"T6","span":{"begin":328,"end":335},"obj":"protein"},{"id":"T7","span":{"begin":374,"end":395},"obj":"protein"},{"id":"T8","span":{"begin":504,"end":511},"obj":"protein"},{"id":"T9","span":{"begin":539,"end":548},"obj":"protein"},{"id":"T10","span":{"begin":600,"end":603},"obj":"cell_type"},{"id":"T11","span":{"begin":864,"end":867},"obj":"cell_type"},{"id":"T12","span":{"begin":892,"end":899},"obj":"protein"},{"id":"T13","span":{"begin":910,"end":913},"obj":"cell_type"},{"id":"T14","span":{"begin":1034,"end":1043},"obj":"protein"},{"id":"T15","span":{"begin":1047,"end":1050},"obj":"cell_type"},{"id":"T16","span":{"begin":1216,"end":1233},"obj":"protein"},{"id":"T17","span":{"begin":1235,"end":1238},"obj":"protein"},{"id":"T18","span":{"begin":1243,"end":1246},"obj":"cell_type"},{"id":"T19","span":{"begin":1454,"end":1463},"obj":"protein"},{"id":"T20","span":{"begin":1657,"end":1664},"obj":"protein"},{"id":"T21","span":{"begin":1680,"end":1689},"obj":"protein"},{"id":"T22","span":{"begin":1704,"end":1707},"obj":"cell_type"},{"id":"T23","span":{"begin":1721,"end":1728},"obj":"protein"},{"id":"T24","span":{"begin":1766,"end":1775},"obj":"protein"},{"id":"T25","span":{"begin":1827,"end":1848},"obj":"DNA"}],"attributes":[{"subj":"T1","pred":"source","obj":"jnlpba-st-training"},{"subj":"T2","pred":"source","obj":"jnlpba-st-training"},{"subj":"T3","pred":"source","obj":"jnlpba-st-training"},{"subj":"T4","pred":"source","obj":"jnlpba-st-training"},{"subj":"T5","pred":"source","obj":"jnlpba-st-training"},{"subj":"T6","pred":"source","obj":"jnlpba-st-training"},{"subj":"T7","pred":"source","obj":"jnlpba-st-training"},{"subj":"T8","pred":"source","obj":"jnlpba-st-training"},{"subj":"T9","pred":"source","obj":"jnlpba-st-training"},{"subj":"T10","pred":"source","obj":"jnlpba-st-training"},{"subj":"T11","pred":"source","obj":"jnlpba-st-training"},{"subj":"T12","pred":"source","obj":"jnlpba-st-training"},{"subj":"T13","pred":"source","obj":"jnlpba-st-training"},{"subj":"T14","pred":"source","obj":"jnlpba-st-training"},{"subj":"T15","pred":"source","obj":"jnlpba-st-training"},{"subj":"T16","pred":"source","obj":"jnlpba-st-training"},{"subj":"T17","pred":"source","obj":"jnlpba-st-training"},{"subj":"T18","pred":"source","obj":"jnlpba-st-training"},{"subj":"T19","pred":"source","obj":"jnlpba-st-training"},{"subj":"T20","pred":"source","obj":"jnlpba-st-training"},{"subj":"T21","pred":"source","obj":"jnlpba-st-training"},{"subj":"T22","pred":"source","obj":"jnlpba-st-training"},{"subj":"T23","pred":"source","obj":"jnlpba-st-training"},{"subj":"T24","pred":"source","obj":"jnlpba-st-training"},{"subj":"T25","pred":"source","obj":"jnlpba-st-training"}]},{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S1","span":{"begin":0,"end":124},"obj":"Sentence"},{"id":"S2","span":{"begin":125,"end":311},"obj":"Sentence"},{"id":"S3","span":{"begin":312,"end":613},"obj":"Sentence"},{"id":"S4","span":{"begin":614,"end":704},"obj":"Sentence"},{"id":"S5","span":{"begin":705,"end":804},"obj":"Sentence"},{"id":"S6","span":{"begin":805,"end":891},"obj":"Sentence"},{"id":"S7","span":{"begin":892,"end":1033},"obj":"Sentence"},{"id":"S8","span":{"begin":1034,"end":1186},"obj":"Sentence"},{"id":"S9","span":{"begin":1187,"end":1313},"obj":"Sentence"},{"id":"S10","span":{"begin":1314,"end":1416},"obj":"Sentence"},{"id":"S11","span":{"begin":1417,"end":1486},"obj":"Sentence"},{"id":"S12","span":{"begin":1487,"end":1607},"obj":"Sentence"},{"id":"S13","span":{"begin":1608,"end":1720},"obj":"Sentence"},{"id":"S14","span":{"begin":1721,"end":1849},"obj":"Sentence"}],"attributes":[{"subj":"S1","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S2","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S3","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S4","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S5","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S6","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S7","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S8","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S9","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S10","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S11","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S12","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S13","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S14","pred":"source","obj":"pubmed-sentences-benchmark"}]},{"project":"GENIAcorpus","denotations":[{"id":"T1","span":{"begin":10,"end":17},"obj":"protein_molecule"},{"id":"T2","span":{"begin":44,"end":61},"obj":"protein_complex"},{"id":"T3","span":{"begin":65,"end":88},"obj":"cell_type"},{"id":"T4","span":{"begin":99,"end":113},"obj":"lipid"},{"id":"T5","span":{"begin":160,"end":174},"obj":"lipid"},{"id":"T6","span":{"begin":185,"end":200},"obj":"lipid"},{"id":"T7","span":{"begin":209,"end":232},"obj":"inorganic"},{"id":"T8","span":{"begin":234,"end":237},"obj":"inorganic"},{"id":"T9","span":{"begin":305,"end":309},"obj":"cell_type"},{"id":"T10","span":{"begin":328,"end":335},"obj":"protein_molecule"},{"id":"T11","span":{"begin":374,"end":395},"obj":"protein_family_or_group"},{"id":"T12","span":{"begin":429,"end":432},"obj":"inorganic"},{"id":"T13","span":{"begin":475,"end":489},"obj":"lipid"},{"id":"T14","span":{"begin":504,"end":511},"obj":"protein_molecule"},{"id":"T15","span":{"begin":539,"end":548},"obj":"protein_complex"},{"id":"T16","span":{"begin":572,"end":579},"obj":"cell_component"},{"id":"T17","span":{"begin":589,"end":596},"obj":"cell_component"},{"id":"T18","span":{"begin":600,"end":603},"obj":"cell_type"},{"id":"T19","span":{"begin":639,"end":653},"obj":"lipid"},{"id":"T20","span":{"begin":688,"end":703},"obj":"multi_cell"},{"id":"T21","span":{"begin":805,"end":821},"obj":"cell_component"},{"id":"T22","span":{"begin":826,"end":844},"obj":"other_organic_compound"},{"id":"T23","span":{"begin":864,"end":867},"obj":"cell_type"},{"id":"T24","span":{"begin":892,"end":899},"obj":"protein_molecule"},{"id":"T25","span":{"begin":910,"end":913},"obj":"cell_type"},{"id":"T26","span":{"begin":1034,"end":1043},"obj":"protein_complex"},{"id":"T27","span":{"begin":1047,"end":1050},"obj":"cell_type"},{"id":"T28","span":{"begin":1216,"end":1225},"obj":"protein_complex"},{"id":"T29","span":{"begin":1235,"end":1238},"obj":"protein_subunit"},{"id":"T30","span":{"begin":1243,"end":1246},"obj":"cell_type"},{"id":"T31","span":{"begin":1288,"end":1302},"obj":"lipid"},{"id":"T32","span":{"begin":1417,"end":1420},"obj":"inorganic"},{"id":"T33","span":{"begin":1454,"end":1463},"obj":"protein_complex"},{"id":"T34","span":{"begin":1478,"end":1485},"obj":"cell_component"},{"id":"T35","span":{"begin":1634,"end":1648},"obj":"lipid"},{"id":"T36","span":{"begin":1657,"end":1664},"obj":"protein_molecule"},{"id":"T37","span":{"begin":1680,"end":1689},"obj":"protein_complex"},{"id":"T38","span":{"begin":1704,"end":1707},"obj":"cell_type"},{"id":"T39","span":{"begin":1721,"end":1728},"obj":"protein_molecule"},{"id":"T40","span":{"begin":1766,"end":1775},"obj":"protein_complex"},{"id":"T41","span":{"begin":1785,"end":1792},"obj":"cell_component"},{"id":"T42","span":{"begin":1827,"end":1848},"obj":"DNA_family_or_group"}],"attributes":[{"subj":"T1","pred":"source","obj":"GENIAcorpus"},{"subj":"T2","pred":"source","obj":"GENIAcorpus"},{"subj":"T3","pred":"source","obj":"GENIAcorpus"},{"subj":"T4","pred":"source","obj":"GENIAcorpus"},{"subj":"T5","pred":"source","obj":"GENIAcorpus"},{"subj":"T6","pred":"source","obj":"GENIAcorpus"},{"subj":"T7","pred":"source","obj":"GENIAcorpus"},{"subj":"T8","pred":"source","obj":"GENIAcorpus"},{"subj":"T9","pred":"source","obj":"GENIAcorpus"},{"subj":"T10","pred":"source","obj":"GENIAcorpus"},{"subj":"T11","pred":"source","obj":"GENIAcorpus"},{"subj":"T12","pred":"source","obj":"GENIAcorpus"},{"subj":"T13","pred":"source","obj":"GENIAcorpus"},{"subj":"T14","pred":"source","obj":"GENIAcorpus"},{"subj":"T15","pred":"source","obj":"GENIAcorpus"},{"subj":"T16","pred":"source","obj":"GENIAcorpus"},{"subj":"T17","pred":"source","obj":"GENIAcorpus"},{"subj":"T18","pred":"source","obj":"GENIAcorpus"},{"subj":"T19","pred":"source","obj":"GENIAcorpus"},{"subj":"T20","pred":"source","obj":"GENIAcorpus"},{"subj":"T21","pred":"source","obj":"GENIAcorpus"},{"subj":"T22","pred":"source","obj":"GENIAcorpus"},{"subj":"T23","pred":"source","obj":"GENIAcorpus"},{"subj":"T24","pred":"source","obj":"GENIAcorpus"},{"subj":"T25","pred":"source","obj":"GENIAcorpus"},{"subj":"T26","pred":"source","obj":"GENIAcorpus"},{"subj":"T27","pred":"source","obj":"GENIAcorpus"},{"subj":"T28","pred":"source","obj":"GENIAcorpus"},{"subj":"T29","pred":"source","obj":"GENIAcorpus"},{"subj":"T30","pred":"source","obj":"GENIAcorpus"},{"subj":"T31","pred":"source","obj":"GENIAcorpus"},{"subj":"T32","pred":"source","obj":"GENIAcorpus"},{"subj":"T33","pred":"source","obj":"GENIAcorpus"},{"subj":"T34","pred":"source","obj":"GENIAcorpus"},{"subj":"T35","pred":"source","obj":"GENIAcorpus"},{"subj":"T36","pred":"source","obj":"GENIAcorpus"},{"subj":"T37","pred":"source","obj":"GENIAcorpus"},{"subj":"T38","pred":"source","obj":"GENIAcorpus"},{"subj":"T39","pred":"source","obj":"GENIAcorpus"},{"subj":"T40","pred":"source","obj":"GENIAcorpus"},{"subj":"T41","pred":"source","obj":"GENIAcorpus"},{"subj":"T42","pred":"source","obj":"GENIAcorpus"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"genia-medco-coref","color":"#93ecdc","default":true},{"id":"metamap-sample","color":"#ecc193"},{"id":"semrep-sample","color":"#a793ec"},{"id":"jnlpba-st-training","color":"#98ec93"},{"id":"pubmed-sentences-benchmark","color":"#ec93b2"},{"id":"GENIAcorpus","color":"#93ccec"}]}]}}