PubMed:10464263
Annnotations
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 155-164 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T2 | 291-300 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T3 | 370-379 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T4 | 444-453 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T5 | 669-678 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T6 | 704-713 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T7 | 734-743 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T8 | 782-791 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T9 | 1009-1015 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GALNT3 |
| T10 | 1020-1026 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GALNT6 |
| T11 | 1194-1203 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T12 | 1411-1420 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T13 | 1422-1431 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T14 | 1488-1497 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 155-164 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T2 | 291-300 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T3 | 370-379 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T4 | 444-453 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T5 | 669-678 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T6 | 704-713 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T7 | 734-743 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T8 | 782-791 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T9 | 1009-1015 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GALNT3 |
| T10 | 1020-1026 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GALNT6 |
| T11 | 1194-1203 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T12 | 1411-1420 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| T13 | 1422-1431 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| T14 | 1488-1497 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-165 | Sentence | denotes | Cloning and characterization of a close homologue of human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase-T3, designated GalNAc-T6. |
| T2 | 166-217 | Sentence | denotes | Evidence for genetic but not functional redundancy. |
| T3 | 218-328 | Sentence | denotes | The UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, designated GalNAc-T3, exhibits unique functions. |
| T4 | 329-417 | Sentence | denotes | Specific acceptor substrates are used by GalNAc-T3 and not by other GalNAc-transferases. |
| T5 | 418-563 | Sentence | denotes | The expression pattern of GalNAc-T3 is restricted, and loss of expression is a characteristic feature of poorly differentiated pancreatic tumors. |
| T6 | 564-733 | Sentence | denotes | In the present study, a sixth human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, designated GalNAc-T6, with high similarity to GalNAc-T3, was characterized. |
| T7 | 734-979 | Sentence | denotes | GalNAc-T6 exhibited high sequence similarity to GalNAc-T3 throughout the coding region, in contrast to the limited similarity that exists between homologous glycosyltransferase genes, which is usually restricted to the putative catalytic domain. |
| T8 | 980-1157 | Sentence | denotes | The genomic organizations of GALNT3 and GALNT6 are identical with the coding regions placed in 10 exons, but the genes are localized differently at 2q31 and 12q13, respectively. |
| T9 | 1158-1270 | Sentence | denotes | Acceptor substrate specificities of GalNAc-T3 and -T6 were similar and different from other GalNAc-transferases. |
| T10 | 1271-1395 | Sentence | denotes | Northern analysis revealed distinct expression patterns, which were confirmed by immunocytology using monoclonal antibodies. |
| T11 | 1396-1560 | Sentence | denotes | In contrast to GalNAc-T3, GalNAc-T6 was expressed in WI38 fibroblast cells, indicating that GalNAc-T6 represents a candidate for synthesis of oncofetal fibronectin. |
| T12 | 1561-1706 | Sentence | denotes | The results demonstrate the existence of genetic redundancy of a polypeptide GalNAc-transferase that does not provide full functional redundancy. |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 545-562 | HP_0002894 | denotes | pancreatic tumors |
| T2 | 556-562 | HP_0002664 | denotes | tumors |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 144-154 | url | denotes | designated |
| PD-GlycoGenes20190927-B_T2 | 155-164 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| PD-GlycoGenes20190927-B_T3 | 222-278 | https://acgg.asia/db/ggdb/info/gg095 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T4 | 222-278 | https://acgg.asia/db/ggdb/info/gg094 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T5 | 222-278 | https://acgg.asia/db/ggdb/info/gg093 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T6 | 222-278 | https://acgg.asia/db/ggdb/info/gg092 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T7 | 222-278 | https://acgg.asia/db/ggdb/info/gg091 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T8 | 222-278 | https://acgg.asia/db/ggdb/info/gg090 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T9 | 222-278 | https://acgg.asia/db/ggdb/info/gg089 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T10 | 222-278 | https://acgg.asia/db/ggdb/info/gg088 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T11 | 222-278 | https://acgg.asia/db/ggdb/info/gg087 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T12 | 280-290 | url | denotes | designated |
| PD-GlycoGenes20190927-B_T13 | 291-300 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| PD-GlycoGenes20190927-B_T14 | 370-379 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| PD-GlycoGenes20190927-B_T15 | 444-453 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| PD-GlycoGenes20190927-B_T16 | 600-656 | https://acgg.asia/db/ggdb/info/gg095 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T17 | 600-656 | https://acgg.asia/db/ggdb/info/gg094 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T18 | 600-656 | https://acgg.asia/db/ggdb/info/gg093 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T19 | 600-656 | https://acgg.asia/db/ggdb/info/gg092 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T20 | 600-656 | https://acgg.asia/db/ggdb/info/gg091 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T21 | 600-656 | https://acgg.asia/db/ggdb/info/gg090 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T22 | 600-656 | https://acgg.asia/db/ggdb/info/gg089 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T23 | 600-656 | https://acgg.asia/db/ggdb/info/gg088 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T24 | 600-656 | https://acgg.asia/db/ggdb/info/gg087 | denotes | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase |
| PD-GlycoGenes20190927-B_T25 | 658-668 | url | denotes | designated |
| PD-GlycoGenes20190927-B_T26 | 669-678 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| PD-GlycoGenes20190927-B_T27 | 704-713 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| PD-GlycoGenes20190927-B_T28 | 734-743 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| PD-GlycoGenes20190927-B_T29 | 782-791 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| PD-GlycoGenes20190927-B_T30 | 1009-1015 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GALNT3 |
| PD-GlycoGenes20190927-B_T31 | 1020-1026 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GALNT6 |
| PD-GlycoGenes20190927-B_T32 | 1194-1203 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| PD-GlycoGenes20190927-B_T33 | 1411-1420 | https://acgg.asia/db/ggdb/info/gg089 | denotes | GalNAc-T3 |
| PD-GlycoGenes20190927-B_T34 | 1422-1431 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
| PD-GlycoGenes20190927-B_T35 | 1488-1497 | https://acgg.asia/db/ggdb/info/gg092 | denotes | GalNAc-T6 |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 155-161 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T2 | 291-297 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T3 | 370-376 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T4 | 397-403 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T5 | 444-450 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T6 | 669-675 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T7 | 704-710 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T8 | 734-740 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T9 | 782-788 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T10 | 1194-1200 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T11 | 1250-1256 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T12 | 1411-1417 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T13 | 1422-1428 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T14 | 1488-1494 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T15 | 1638-1644 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T17 | 226-232 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T22 | 604-610 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 545-562 | Disease | denotes | pancreatic tumors | http://purl.obolibrary.org/obo/MONDO_0009831|http://purl.obolibrary.org/obo/MONDO_0021040 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 545-562 | Phenotype | denotes | pancreatic tumors | HP:0002894 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 155-161 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T2 | 291-297 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T3 | 370-376 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T4 | 397-403 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T5 | 444-450 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T6 | 669-675 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T7 | 704-710 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T8 | 734-740 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T9 | 782-788 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T10 | 1194-1200 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T11 | 1250-1256 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T12 | 1411-1417 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T13 | 1422-1428 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T14 | 1488-1494 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T15 | 1638-1644 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 545-562 | Phenotype | denotes | pancreatic tumors | HP:0002894 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1454-1464 | Cell | denotes | fibroblast | http://purl.obolibrary.org/obo/CL:0000057 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 545-562 | Disease | denotes | pancreatic tumors | MONDO:0021040 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 53-58 | Organism | denotes | human | 9606 |
| T2 | 594-599 | Organism | denotes | human | 9606 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-165 | Sentence | denotes | Cloning and characterization of a close homologue of human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase-T3, designated GalNAc-T6. |
| T2 | 166-217 | Sentence | denotes | Evidence for genetic but not functional redundancy. |
| T3 | 218-328 | Sentence | denotes | The UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, designated GalNAc-T3, exhibits unique functions. |
| T4 | 329-417 | Sentence | denotes | Specific acceptor substrates are used by GalNAc-T3 and not by other GalNAc-transferases. |
| T5 | 418-563 | Sentence | denotes | The expression pattern of GalNAc-T3 is restricted, and loss of expression is a characteristic feature of poorly differentiated pancreatic tumors. |
| T6 | 564-733 | Sentence | denotes | In the present study, a sixth human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, designated GalNAc-T6, with high similarity to GalNAc-T3, was characterized. |
| T7 | 734-979 | Sentence | denotes | GalNAc-T6 exhibited high sequence similarity to GalNAc-T3 throughout the coding region, in contrast to the limited similarity that exists between homologous glycosyltransferase genes, which is usually restricted to the putative catalytic domain. |
| T8 | 980-1157 | Sentence | denotes | The genomic organizations of GALNT3 and GALNT6 are identical with the coding regions placed in 10 exons, but the genes are localized differently at 2q31 and 12q13, respectively. |
| T9 | 1158-1270 | Sentence | denotes | Acceptor substrate specificities of GalNAc-T3 and -T6 were similar and different from other GalNAc-transferases. |
| T10 | 1271-1395 | Sentence | denotes | Northern analysis revealed distinct expression patterns, which were confirmed by immunocytology using monoclonal antibodies. |
| T11 | 1396-1560 | Sentence | denotes | In contrast to GalNAc-T3, GalNAc-T6 was expressed in WI38 fibroblast cells, indicating that GalNAc-T6 represents a candidate for synthesis of oncofetal fibronectin. |
| T12 | 1561-1706 | Sentence | denotes | The results demonstrate the existence of genetic redundancy of a polypeptide GalNAc-transferase that does not provide full functional redundancy. |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1454-1464 | Body_part | denotes | fibroblast | http://purl.obolibrary.org/obo/CL_0000057 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 1454-1464 | Body_part | denotes | fibroblast | FMA:63877 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 53-58 | OrganismTaxon | denotes | human | 9606 |
| T2 | 594-599 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1454-1464 | Body_part | denotes | fibroblast | http://purl.obolibrary.org/obo/CL_0000057 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1454-1464 | Cell | denotes | fibroblast | http://purl.obolibrary.org/obo/CL:0000057 |