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PubMed:10415609 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 478-487 protein denotes cytokines
T2 489-493 protein denotes IL-2
T3 495-499 protein denotes IL-6
T4 501-510 protein denotes TNF-alpha
T5 512-517 protein denotes IL-10
T6 522-546 cell_type denotes peripheral T lymphocytes
T7 585-590 protein denotes NF-kB
T8 615-641 cell_line denotes activated Jurkat cell line
T9 725-733 protein denotes cytokine
T10 748-761 cell_type denotes T lymphocytes
T11 816-821 protein denotes NF-kB
T12 825-837 cell_line denotes Jurkat cells
T13 865-874 protein denotes cytokines
T14 999-1004 protein denotes NF-kB
T15 1214-1234 protein denotes transcription factor

genia-medco-coref

Id Subject Object Predicate Lexical cue
C23 54-96 NP denotes different glucocorticoid hormone compounds
C1 98-137 NP denotes Different glucocorticoid hormones (GCH)
C2 195-200 NP denotes their
C3 258-261 NP denotes GCH
C4 228-261 NP denotes The mechanism(s) of action of GCH
C5 313-317 NP denotes they
C6 396-412 NP denotes prednisone (PDN)
C17 414-431 NP denotes deflazacort (DFC)
C15 437-456 NP denotes dexamethasone (DXM)
C18 396-456 NP denotes prednisone (PDN), deflazacort (DFC), and dexamethasone (DXM)
C10 478-518 NP denotes cytokines (IL-2, IL-6, TNF-alpha, IL-10)
C8 460-546 NP denotes the production of cytokines (IL-2, IL-6, TNF-alpha, IL-10) by peripheral T lymphocytes
C7 671-694 NP denotes the three GCH molecules
C9 725-761 NP denotes cytokine production by T lymphocytes
C13 816-821 NP denotes NF-kB
C11 857-887 NP denotes all the cytokines investigated
C12 939-952 NP denotes the three GCH
C16 961-964 NP denotes DXM
C20 975-995 NP denotes the binding activity
C14 999-1004 NP denotes NF-kB
C19 1015-1019 NP denotes that
C21 1023-1026 NP denotes DFC
C22 1031-1034 NP denotes PDN
C24 1086-1109 NP denotes different GCH compounds
C25 1126-1131 NP denotes their
R1 C1 C23 coref-other Different glucocorticoid hormones (GCH),different glucocorticoid hormone compounds
R2 C2 C1 coref-pron their,Different glucocorticoid hormones (GCH)
R3 C3 C1 coref-ident GCH,Different glucocorticoid hormones (GCH)
R4 C5 C4 coref-pron they,The mechanism(s) of action of GCH
R5 C7 C6 coref-ident the three GCH molecules,prednisone (PDN)
R6 C9 C8 coref-ident cytokine production by T lymphocytes,"the production of cytokines (IL-2, IL-6, TNF-alpha, IL-10) by peripheral T lymphocytes"
R7 C11 C10 coref-ident all the cytokines investigated,"cytokines (IL-2, IL-6, TNF-alpha, IL-10)"
R8 C12 C7 coref-ident the three GCH,the three GCH molecules
R9 C16 C15 coref-ident DXM,dexamethasone (DXM)
R10 C14 C13 coref-ident NF-kB,NF-kB
R11 C19 C20 coref-pron that,the binding activity
R12 C21 C17 coref-ident DFC,deflazacort (DFC)
R13 C22 C18 coref-ident PDN,"prednisone (PDN), deflazacort (DFC), and dexamethasone (DXM)"
R14 C24 C23 coref-other different GCH compounds,different glucocorticoid hormone compounds
R15 C25 C24 coref-pron their,different GCH compounds

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-97 Sentence denotes Possible differences in the mechanism(s) of action of different glucocorticoid hormone compounds.
S2 98-227 Sentence denotes Different glucocorticoid hormones (GCH) show differences in the intensity and in the kinetics of their immunomodulating activity.
S3 228-364 Sentence denotes The mechanism(s) of action of GCH is under investigation, but is has been noted that they exert immune activity via the genomic pathway.
S4 365-642 Sentence denotes We have studied the effects of prednisone (PDN), deflazacort (DFC), and dexamethasone (DXM) on the production of cytokines (IL-2, IL-6, TNF-alpha, IL-10) by peripheral T lymphocytes, and the effects on the inhibition of NF-kB DNA binding activity by activated Jurkat cell line.
S5 643-1035 Sentence denotes The data obtained show that the three GCH molecules exert an immunosuppression on cytokine production by T lymphocytes and a strong decrease in the nuclear translocation of NF-kB in Jurkat cells; moreover, (a) not all the cytokines investigated were affected, and not with the same intensity, by the three GCH and (b) DXM inhibited the binding activity of NF-kB less than that of DFC and PDN.
S6 1036-1235 Sentence denotes These data are in agreement with the concept that different GCH compounds might differ in their binding and affinity properties, tissue-specific metabolism, and interaction with transcription factor.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 64-96 lipid denotes glucocorticoid hormone compounds
T2 108-133 lipid denotes glucocorticoid hormones (
T3 133-136 lipid denotes GCH
T4 201-226 other_name denotes immunomodulating activity
T5 258-261 lipid denotes GCH
T6 324-339 other_name denotes immune activity
T7 348-363 other_name denotes genomic pathway
T8 396-408 lipid denotes prednisone (
T9 408-411 lipid denotes PDN
T10 414-427 lipid denotes deflazacort (
T11 427-430 lipid denotes DFC
T12 437-452 lipid denotes dexamethasone (
T13 452-455 lipid denotes DXM
T14 478-487 protein_family_or_group denotes cytokines
T15 489-493 protein_molecule denotes IL-2
T16 495-499 protein_molecule denotes IL-6
T17 501-510 protein_molecule denotes TNF-alpha
T18 512-517 protein_molecule denotes IL-10
T19 522-546 cell_type denotes peripheral T lymphocytes
T20 585-590 protein_molecule denotes NF-kB
T21 615-641 cell_line denotes activated Jurkat cell line
T22 681-684 lipid denotes GCH
T23 704-721 other_name denotes immunosuppression
T24 725-733 protein_family_or_group denotes cytokine
T25 748-761 cell_type denotes T lymphocytes
T26 791-812 other_name denotes nuclear translocation
T27 816-821 protein_molecule denotes NF-kB
T28 825-837 cell_line denotes Jurkat cells
T29 865-874 protein_family_or_group denotes cytokines
T30 949-952 lipid denotes GCH
T31 961-964 lipid denotes DXM
T32 979-995 other_name denotes binding activity
T33 999-1004 protein_molecule denotes NF-kB
T34 1023-1026 lipid denotes DFC
T35 1031-1034 lipid denotes PDN
T36 1096-1099 lipid denotes GCH
T37 1132-1139 other_name denotes binding
T38 1144-1163 other_name denotes affinity properties
T39 1165-1191 other_name denotes tissue-specific metabolism
T40 1214-1234 protein_family_or_group denotes transcription factor