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PubMed:10411007 JSONTXT

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PubmedHPO

Id Subject Object Predicate Lexical cue
T1 142-147 HP_0002664 denotes tumor

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-25 protein denotes ETS transcription factors
T2 63-75 DNA denotes third intron
T3 79-88 protein denotes TNF-alpha
T4 126-138 DNA denotes third intron
T5 142-169 protein denotes tumor necrosis factor alpha
T6 171-180 protein denotes TNF-alpha
T7 185-203 DNA denotes reporter construct
T8 219-237 DNA denotes 5'-flanking region
T9 251-265 DNA denotes TNF-alpha gene
T10 312-342 cell_line denotes RAW264.7 macrophage-like cells
T11 364-376 DNA denotes third intron
T12 380-389 protein denotes TNF-alpha
T13 438-449 protein denotes CAT protein
T14 488-512 DNA denotes conserved 20-bp sequence
T15 534-540 DNA denotes intron
T16 549-585 protein denotes dominant-negative ets-binding factor
T17 614-627 DNA denotes reporter gene
T18 677-715 DNA denotes ets transcription factor binding sites
T19 839-843 protein denotes GABP
T20 887-901 cell_line denotes RAW264.7 cells
T21 945-976 cell_line denotes bone marrow-derived macrophages
T22 1010-1026 protein denotes interferon-gamma
T23 1064-1089 protein denotes ets transcription factors
T24 1111-1120 protein denotes TNF-alpha

genia-medco-coref

Id Subject Object Predicate Lexical cue
C18 0-25 NP denotes ETS transcription factors
C1 79-88 NP denotes TNF-alpha
C3 59-88 NP denotes the third intron of TNF-alpha
C2 142-181 NP denotes tumor necrosis factor alpha (TNF-alpha)
C4 122-181 NP denotes the third intron of tumor necrosis factor alpha (TNF-alpha)
C8 183-265 NP denotes A reporter construct containing the 5'-flanking region of the mouse TNF-alpha gene
C14 312-342 NP denotes RAW264.7 macrophage-like cells
C5 380-389 NP denotes TNF-alpha
C6 360-389 NP denotes the third intron of TNF-alpha
C9 393-407 NP denotes this construct
C7 530-540 NP denotes the intron
C10 629-651 NP denotes Mutations of this site
C11 652-656 NP denotes that
C12 754-784 NP denotes The major transcription factor
C13 785-789 NP denotes that
C15 887-901 NP denotes RAW264.7 cells
C17 1064-1089 NP denotes ets transcription factors
C16 1111-1120 NP denotes TNF-alpha
R1 C2 C1 coref-ident tumor necrosis factor alpha (TNF-alpha),TNF-alpha
R2 C4 C3 coref-ident the third intron of tumor necrosis factor alpha (TNF-alpha),the third intron of TNF-alpha
R3 C5 C2 coref-ident TNF-alpha,tumor necrosis factor alpha (TNF-alpha)
R4 C6 C4 coref-ident the third intron of TNF-alpha,the third intron of tumor necrosis factor alpha (TNF-alpha)
R5 C9 C8 coref-ident this construct,A reporter construct containing the 5'-flanking region of the mouse TNF-alpha gene
R6 C7 C6 coref-ident the intron,the third intron of TNF-alpha
R7 C11 C10 coref-relat that,Mutations of this site
R8 C13 C12 coref-relat that,The major transcription factor
R9 C15 C14 coref-ident RAW264.7 cells,RAW264.7 macrophage-like cells
R10 C17 C18 coref-ident ets transcription factors,ETS transcription factors
R11 C16 C5 coref-ident TNF-alpha,TNF-alpha

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-89 Sentence denotes ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha.
S2 90-182 Sentence denotes We describe an enhancer site in the third intron of tumor necrosis factor alpha (TNF-alpha).
S3 183-343 Sentence denotes A reporter construct containing the 5'-flanking region of the mouse TNF-alpha gene displayed weak activity when transfected into RAW264.7 macrophage-like cells.
S4 344-450 Sentence denotes The addition of the third intron of TNF-alpha to this construct resulted in an enhancement of CAT protein.
S5 451-628 Sentence denotes This enhancement was eliminated if a conserved 20-bp sequence was removed from the intron or if a dominant-negative ets-binding factor was co-transfected with the reporter gene.
S6 629-753 Sentence denotes Mutations of this site that destroyed potential ets transcription factor binding sites had reduced transcriptional activity.
S7 754-883 Sentence denotes The major transcription factor that bound to the oligonucleotide was confirmed to be GABP by supershift and competition analysis.
S8 884-1037 Sentence denotes In RAW264.7 cells, the binding was constitutive, however, in bone marrow-derived macrophages binding activity was shown to be interferon-gamma inducible.
S9 1038-1121 Sentence denotes This may imply a role for ets transcription factors in the production of TNF-alpha.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-25 protein_family_or_group denotes ETS transcription factors
T2 38-55 other_name denotes enhancer activity
T3 63-75 DNA_domain_or_region denotes third intron
T4 79-88 protein_molecule denotes TNF-alpha
T5 126-138 DNA_domain_or_region denotes third intron
T6 142-147 tissue denotes tumor
T7 171-180 protein_molecule denotes TNF-alpha
T8 185-203 DNA_molecule denotes reporter construct
T9 219-237 DNA_domain_or_region denotes 5'-flanking region
T10 251-260 protein_molecule denotes TNF-alpha
T11 312-342 cell_line denotes RAW264.7 macrophage-like cells
T12 364-376 DNA_domain_or_region denotes third intron
T13 380-389 protein_molecule denotes TNF-alpha
T14 438-449 protein_family_or_group denotes CAT protein
T15 488-512 DNA_domain_or_region denotes conserved 20-bp sequence
T16 534-540 DNA_domain_or_region denotes intron
T17 549-585 protein_family_or_group denotes dominant-negative ets-binding factor
T18 614-627 DNA_family_or_group denotes reporter gene
T19 677-701 protein_family_or_group denotes ets transcription factor
T20 728-752 other_name denotes transcriptional activity
T21 803-818 polynucleotide denotes oligonucleotide
T22 839-843 protein_molecule denotes GABP
T23 847-857 other_name denotes supershift
T24 862-882 other_name denotes competition analysis
T25 887-901 cell_line denotes RAW264.7 cells
T26 945-964 cell_line denotes bone marrow-derived
T27 965-976 cell_type denotes macrophages
T28 1010-1026 protein_molecule denotes interferon-gamma
T29 1064-1089 protein_family_or_group denotes ets transcription factors
T30 1111-1120 protein_molecule denotes TNF-alpha