PubMed:10411003
Annnotations
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 576-581 | HP_0002664 | denotes | tumor |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 22-36 | protein | denotes | interleukin-11 |
| T2 | 88-102 | protein | denotes | interleukin-11 |
| T3 | 104-109 | protein | denotes | IL-11 |
| T4 | 132-150 | protein | denotes | IgG immune complex |
| T5 | 187-197 | RNA | denotes | IL-11 mRNA |
| T6 | 307-312 | protein | denotes | IL-11 |
| T7 | 399-410 | cell_type | denotes | neutrophils |
| T8 | 441-448 | protein | denotes | albumin |
| T9 | 493-498 | protein | denotes | IL-11 |
| T10 | 528-537 | protein | denotes | NF-kappaB |
| T11 | 576-603 | protein | denotes | tumor necrosis factor alpha |
| T12 | 605-614 | protein | denotes | TNF-alpha |
| T13 | 688-708 | protein | denotes | lung vascular ICAM-1 |
| T14 | 733-738 | protein | denotes | IL-11 |
| T15 | 779-793 | protein | denotes | CXC chemokines |
| T16 | 795-828 | protein | denotes | macrophage inflammatory protein-2 |
| T17 | 830-835 | protein | denotes | MIP-2 |
| T18 | 841-886 | protein | denotes | cytokine-inducible neutrophil chemoattractant |
| T19 | 888-892 | protein | denotes | CINC |
| T20 | 911-916 | protein | denotes | IL-11 |
| T21 | 938-948 | protein | denotes | chemokines |
| T22 | 993-998 | protein | denotes | IL-11 |
| T23 | 1025-1030 | protein | denotes | IL-11 |
| T24 | 1036-1055 | protein | denotes | regulatory cytokine |
| T25 | 1188-1197 | protein | denotes | NF-kappaB |
| T26 | 1235-1244 | protein | denotes | TNF-alpha |
| T27 | 1275-1295 | protein | denotes | lung vascular ICAM-1 |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 22-36 | NP | denotes | interleukin-11 |
| C2 | 88-110 | NP | denotes | interleukin-11 (IL-11) |
| C5 | 493-498 | NP | denotes | IL-11 |
| C12 | 552-556 | NP | denotes | lung |
| C16 | 576-615 | NP | denotes | tumor necrosis factor alpha (TNF-alpha) |
| C18 | 688-708 | NP | denotes | lung vascular ICAM-1 |
| C20 | 671-708 | NP | denotes | up-regulation of lung vascular ICAM-1 |
| C6 | 733-738 | NP | denotes | IL-11 |
| C8 | 775-793 | NP | denotes | the CXC chemokines |
| C7 | 911-916 | NP | denotes | IL-11 |
| C9 | 932-948 | NP | denotes | these chemokines |
| C10 | 993-998 | NP | denotes | IL-11 |
| C11 | 1025-1030 | NP | denotes | IL-11 |
| C13 | 1059-1067 | NP | denotes | the lung |
| C14 | 1113-1116 | NP | denotes | its |
| C15 | 1169-1172 | NP | denotes | its |
| C17 | 1235-1244 | NP | denotes | TNF-alpha |
| C19 | 1275-1295 | NP | denotes | lung vascular ICAM-1 |
| C21 | 1258-1295 | NP | denotes | up-regulation of lung vascular ICAM-1 |
| R1 | C2 | C1 | coref-ident | interleukin-11 (IL-11),interleukin-11 |
| R2 | C5 | C2 | coref-ident | IL-11,interleukin-11 (IL-11) |
| R3 | C6 | C5 | coref-ident | IL-11,IL-11 |
| R4 | C7 | C6 | coref-ident | IL-11,IL-11 |
| R5 | C9 | C8 | coref-ident | these chemokines,the CXC chemokines |
| R6 | C10 | C7 | coref-ident | IL-11,IL-11 |
| R7 | C11 | C10 | coref-ident | IL-11,IL-11 |
| R8 | C13 | C12 | coref-ident | the lung,lung |
| R9 | C14 | C11 | coref-pron | its,IL-11 |
| R10 | C15 | C11 | coref-pron | its,IL-11 |
| R11 | C17 | C16 | coref-ident | TNF-alpha,tumor necrosis factor alpha (TNF-alpha) |
| R12 | C19 | C18 | coref-ident | lung vascular ICAM-1,lung vascular ICAM-1 |
| R13 | C21 | C20 | coref-ident | up-regulation of lung vascular ICAM-1,up-regulation of lung vascular ICAM-1 |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-75 | Sentence | denotes | Regulatory effects of interleukin-11 during acute lung inflammatory injury. |
| S2 | 76-186 | Sentence | denotes | The role of interleukin-11 (IL-11) was evaluated in the IgG immune complex model of acute lung injury in rats. |
| S3 | 187-281 | Sentence | denotes | IL-11 mRNA and protein were both up-regulated during the course of this inflammatory response. |
| S4 | 282-449 | Sentence | denotes | Exogenously administered IL-11 substantially reduced, in a dose-dependent manner, the intrapulmonary accumulation of neutrophils and the lung vascular leak of albumin. |
| S5 | 450-709 | Sentence | denotes | These in vivo anti-inflammatory effects of IL-11 were associated with reduced NF-kappaB activation in lung, reduced levels of tumor necrosis factor alpha (TNF-alpha) in bronchoalveolar lavage (BAL) fluids, and diminished up-regulation of lung vascular ICAM-1. |
| S6 | 710-949 | Sentence | denotes | It is interesting that IL-11 did not affect BAL fluid content of the CXC chemokines, macrophage inflammatory protein-2 (MIP-2) and cytokine-inducible neutrophil chemoattractant (CINC); the presence of IL-11 did not affect these chemokines. |
| S7 | 950-999 | Sentence | denotes | However, BAL content of C5a was reduced by IL-11. |
| S8 | 1000-1296 | Sentence | denotes | These data indicate that IL-11 is a regulatory cytokine in the lung and that, like other members of this family, its anti-inflammatory properties appear to be linked to its suppression of NF-kappaB activation, diminished production of TNF-alpha, and reduced up-regulation of lung vascular ICAM-1. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 22-36 | protein_molecule | denotes | interleukin-11 |
| T2 | 44-74 | other_name | denotes | acute lung inflammatory injury |
| T3 | 88-102 | protein_molecule | denotes | interleukin-11 |
| T4 | 104-109 | protein_molecule | denotes | IL-11 |
| T5 | 132-150 | protein_complex | denotes | IgG immune complex |
| T6 | 160-177 | other_name | denotes | acute lung injury |
| T7 | 181-185 | multi_cell | denotes | rats |
| T8 | 187-192 | protein_molecule | denotes | IL-11 |
| T9 | 259-280 | other_name | denotes | inflammatory response |
| T10 | 307-312 | protein_molecule | denotes | IL-11 |
| T11 | 368-395 | other_name | denotes | intrapulmonary accumulation |
| T12 | 399-410 | cell_type | denotes | neutrophils |
| T13 | 419-437 | other_name | denotes | lung vascular leak |
| T14 | 441-448 | protein_molecule | denotes | albumin |
| T15 | 493-498 | protein_molecule | denotes | IL-11 |
| T16 | 528-537 | protein_complex | denotes | NF-kappaB |
| T17 | 576-603 | protein_molecule | denotes | tumor necrosis factor alpha |
| T18 | 605-614 | protein_molecule | denotes | TNF-alpha |
| T19 | 619-654 | tissue | denotes | bronchoalveolar lavage (BAL) fluids |
| T20 | 688-708 | protein_molecule | denotes | lung vascular ICAM-1 |
| T21 | 733-738 | protein_molecule | denotes | IL-11 |
| T22 | 754-763 | tissue | denotes | BAL fluid |
| T23 | 779-793 | protein_family_or_group | denotes | CXC chemokines |
| T24 | 795-828 | protein_molecule | denotes | macrophage inflammatory protein-2 |
| T25 | 830-835 | protein_molecule | denotes | MIP-2 |
| T26 | 841-849 | protein_family_or_group | denotes | cytokine |
| T27 | 888-892 | protein_molecule | denotes | CINC |
| T28 | 911-916 | protein_molecule | denotes | IL-11 |
| T29 | 938-948 | protein_family_or_group | denotes | chemokines |
| T30 | 959-970 | other_name | denotes | BAL content |
| T31 | 974-977 | other_name | denotes | C5a |
| T32 | 993-998 | protein_molecule | denotes | IL-11 |
| T33 | 1025-1030 | protein_molecule | denotes | IL-11 |
| T34 | 1036-1046 | protein_family_or_group | denotes | regulatory |
| T35 | 1047-1055 | protein_family_or_group | denotes | cytokine |
| T36 | 1063-1067 | body_part | denotes | lung |
| T37 | 1117-1145 | other_name | denotes | anti-inflammatory properties |
| T38 | 1188-1197 | protein_complex | denotes | NF-kappaB |
| T39 | 1235-1244 | protein_molecule | denotes | TNF-alpha |
| T40 | 1275-1295 | protein_molecule | denotes | lung vascular ICAM-1 |