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PubMed:10406848 JSONTXT

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CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 1788-1807 Cell denotes activated microglia http://purl.obolibrary.org/obo/CL:0002629
T2 1798-1807 Cell denotes microglia http://purl.obolibrary.org/obo/CL:0000129

Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 970-990 https://glytoucan.org/Structures/Glycans/G64581RP denotes N -acetylglucosamine
T2 1105-1112 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T3 1507-1518 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 970-990 Glycan_Motif denotes N -acetylglucosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G64581RP
T2 1105-1112 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ
T3 1507-1518 Glycan_Motif denotes sialic acid https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 970-990 https://glytoucan.org/Structures/Glycans/G64581RP denotes N -acetylglucosamine
T2 1105-1112 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose
T3 1507-1518 https://glytoucan.org/Structures/Glycans/G81533KY denotes sialic acid

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 128-133 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T2 893-898 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T3 1027-1035 http://purl.obolibrary.org/obo/MAT_0000086 denotes antennae
T4 1232-1237 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 19-22 FMAID:265384 denotes CNS
_T2 32-52 FMAID:265717 denotes extracellular matrix
_T3 32-52 FMAID:165194 denotes extracellular matrix
_T4 53-65 FMAID:62925 denotes glycoprotein
_T5 53-65 FMAID:167256 denotes glycoprotein
_T6 67-75 FMAID:167259 denotes tenascin
_T7 67-75 FMAID:62928 denotes tenascin
_T8 128-133 FMAID:146514 denotes brain
_T9 128-133 FMAID:50801 denotes brain
_T10 178-186 FMAID:62928 denotes tenascin
_T11 178-186 FMAID:167259 denotes tenascin
_T12 194-217 FMAID:162359 denotes of extracellular matrix
_T13 194-217 FMAID:165194 denotes of extracellular matrix
_T14 194-217 FMAID:9672 denotes of extracellular matrix
_T15 197-217 FMAID:265717 denotes extracellular matrix
_T16 218-231 FMAID:167256 denotes glycoproteins
_T17 218-231 FMAID:62925 denotes glycoproteins
_T18 233-241 FMAID:62928 denotes tenascin
_T19 233-241 FMAID:167259 denotes tenascin
_T20 274-277 FMAID:265384 denotes CNS
_T21 312-323 FMAID:167340 denotes myelination
_T22 312-323 FMAID:62977 denotes myelination
_T23 328-334 FMAID:165274 denotes axonal
_T24 328-334 FMAID:67308 denotes axonal
_T25 430-433 FMAID:265384 denotes CNS
_T26 434-439 FMAID:67308 denotes axons
_T27 434-439 FMAID:165274 denotes axons
_T28 488-497 FMAID:62928 denotes tenascins
_T29 488-497 FMAID:167259 denotes tenascins
_T30 561-568 FMAID:67257 denotes protein
_T31 561-568 FMAID:165447 denotes protein
_T32 627-639 FMAID:197276 denotes carbohydrate
_T33 627-639 FMAID:82737 denotes carbohydrate
_T34 802-810 FMAID:62928 denotes tenascin
_T35 802-810 FMAID:167259 denotes tenascin
_T36 893-898 FMAID:50801 denotes brain
_T37 893-898 FMAID:146514 denotes brain
_T38 930-933 FMAID:117478 denotes arm
_T39 930-933 FMAID:24890 denotes arm
_T40 970-990 FMAID:196781 denotes N -acetylglucosamine
_T41 970-990 FMAID:82787 denotes N -acetylglucosamine
_T42 1105-1112 FMAID:82801 denotes mannose
_T43 1105-1112 FMAID:196796 denotes mannose
_T44 1140-1143 FMAID:24890 denotes arm
_T45 1140-1143 FMAID:117478 denotes arm
_T46 1232-1237 FMAID:146514 denotes brain
_T47 1232-1237 FMAID:50801 denotes brain
_T48 1238-1244 FMAID:256050 denotes tissue
_T49 1683-1691 FMAID:62928 denotes tenascin
_T50 1683-1691 FMAID:167259 denotes tenascin
_T51 1713-1716 FMAID:265384 denotes CNS
_T52 1733-1739 FMAID:62977 denotes myelin
_T53 1733-1739 FMAID:167340 denotes myelin
_T54 1751-1763 FMAID:62925 denotes glycoprotein
_T55 1751-1763 FMAID:167256 denotes glycoprotein
_T56 1798-1807 FMAID:169342 denotes microglia

uniprot-human

Id Subject Object Predicate Lexical cue
T1 67-75 http://www.uniprot.org/uniprot/P24821 denotes tenascin
T2 178-186 http://www.uniprot.org/uniprot/P24821 denotes tenascin
T3 233-241 http://www.uniprot.org/uniprot/P24821 denotes tenascin
T4 802-810 http://www.uniprot.org/uniprot/P24821 denotes tenascin
T5 1683-1691 http://www.uniprot.org/uniprot/P24821 denotes tenascin
T6 67-77 http://www.uniprot.org/uniprot/Q92752 denotes tenascin-R
T7 233-243 http://www.uniprot.org/uniprot/Q92752 denotes tenascin-R
T8 802-812 http://www.uniprot.org/uniprot/Q92752 denotes tenascin-R
T9 1683-1693 http://www.uniprot.org/uniprot/Q92752 denotes tenascin-R
T10 1733-1763 http://www.uniprot.org/uniprot/P20916 denotes myelin associated glycoprotein
T11 1772-1784 http://www.uniprot.org/uniprot/Q9BZZ2 denotes sialoadhesin

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 67-75 http://www.uniprot.org/uniprot/Q80YX1 denotes tenascin
T2 178-186 http://www.uniprot.org/uniprot/Q80YX1 denotes tenascin
T3 233-241 http://www.uniprot.org/uniprot/Q80YX1 denotes tenascin
T4 802-810 http://www.uniprot.org/uniprot/Q80YX1 denotes tenascin
T5 1683-1691 http://www.uniprot.org/uniprot/Q80YX1 denotes tenascin
T6 67-77 http://www.uniprot.org/uniprot/Q8BYI9 denotes tenascin-R
T7 233-243 http://www.uniprot.org/uniprot/Q8BYI9 denotes tenascin-R
T8 802-812 http://www.uniprot.org/uniprot/Q8BYI9 denotes tenascin-R
T9 1683-1693 http://www.uniprot.org/uniprot/Q8BYI9 denotes tenascin-R
T10 1733-1763 http://www.uniprot.org/uniprot/P20917 denotes myelin associated glycoprotein
T11 1772-1784 http://www.uniprot.org/uniprot/Q62230 denotes sialoadhesin

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 658-662 http://purl.bioontology.org/ontology/NCBITAXON/9973 denotes many
T2 1027-1035 http://purl.bioontology.org/ontology/NCBITAXON/293542 denotes antennae
T3 1238-1244 http://purl.bioontology.org/ontology/STY/T024 denotes tissue
T4 1798-1807 http://purl.bioontology.org/ontology/NCBITAXON/493316 denotes microglia

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-158 Sentence denotes Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans.
TextSentencer_T2 159-278 Sentence denotes As a member of the tenascin family of extracellular matrix glycoproteins, tenascin-R is located exclusively in the CNS.
TextSentencer_T3 279-457 Sentence denotes It is believed to play a role in myelination and axonal stabilization and, through repulsive properties, may contribute to the lack of regeneration of CNS axons following damage.
TextSentencer_T4 458-569 Sentence denotes The contrary functions of the tenascins have been localized to the different structural domains of the protein.
TextSentencer_T5 570-727 Sentence denotes However, little is known concerning the influence of the carbohydrate conjugated to the many potential sites for N - and O -glycosylation (10-20% by weight).
TextSentencer_T6 728-873 Sentence denotes As a first analytical requirement, we show that >80% of the N -glycans in tenascin-R are neutral and dominated by complex biantennary structures.
TextSentencer_T7 874-1047 Sentence denotes These display the "brain-type" characteristics of outer-arm- and core-fucosylation, a bisecting N -acetylglucosamine and, significantly, an abundance of antennae truncation.
TextSentencer_T8 1048-1216 Sentence denotes In some structures, truncation resulted in only a single mannose residue remaining on the 3-arm, a particularly unusual consequence of the N -glycan processing pathway.
TextSentencer_T9 1217-1323 Sentence denotes In contrast to brain tissue, hybrid and oligomannosidic N -glycans were either absent or in low abundance.
TextSentencer_T10 1324-1392 Sentence denotes A high relative abundance of O -linked sialylated glycans was found.
TextSentencer_T11 1393-1528 Sentence denotes This was associated with a significant potential for O -linked glycosylation sites and multivalent display of the sialic acid residues.
TextSentencer_T12 1529-1637 Sentence denotes These O -glycans were dominated by the disialylated structure, NeuAcalpha2-3Galbeta1-3(NeuAcalpha2-6)GalNAc.
TextSentencer_T13 1638-1821 Sentence denotes The possibility that these O -glycans enable tenascin-R to interact in the CNS either with the myelin associated glycoprotein or with sialoadhesin on activated microglia is discussed.
T1 0-158 Sentence denotes Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans.
T2 159-278 Sentence denotes As a member of the tenascin family of extracellular matrix glycoproteins, tenascin-R is located exclusively in the CNS.
T3 279-457 Sentence denotes It is believed to play a role in myelination and axonal stabilization and, through repulsive properties, may contribute to the lack of regeneration of CNS axons following damage.
T4 458-569 Sentence denotes The contrary functions of the tenascins have been localized to the different structural domains of the protein.
T5 570-727 Sentence denotes However, little is known concerning the influence of the carbohydrate conjugated to the many potential sites for N - and O -glycosylation (10-20% by weight).
T6 728-873 Sentence denotes As a first analytical requirement, we show that >80% of the N -glycans in tenascin-R are neutral and dominated by complex biantennary structures.
T7 874-1047 Sentence denotes These display the "brain-type" characteristics of outer-arm- and core-fucosylation, a bisecting N -acetylglucosamine and, significantly, an abundance of antennae truncation.
T8 1048-1216 Sentence denotes In some structures, truncation resulted in only a single mannose residue remaining on the 3-arm, a particularly unusual consequence of the N -glycan processing pathway.
T9 1217-1323 Sentence denotes In contrast to brain tissue, hybrid and oligomannosidic N -glycans were either absent or in low abundance.
T10 1324-1392 Sentence denotes A high relative abundance of O -linked sialylated glycans was found.
T11 1393-1528 Sentence denotes This was associated with a significant potential for O -linked glycosylation sites and multivalent display of the sialic acid residues.
T12 1529-1637 Sentence denotes These O -glycans were dominated by the disialylated structure, NeuAcalpha2-3Galbeta1-3(NeuAcalpha2-6)GalNAc.
T13 1638-1821 Sentence denotes The possibility that these O -glycans enable tenascin-R to interact in the CNS either with the myelin associated glycoprotein or with sialoadhesin on activated microglia is discussed.
T1 0-158 Sentence denotes Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans.
T2 159-278 Sentence denotes As a member of the tenascin family of extracellular matrix glycoproteins, tenascin-R is located exclusively in the CNS.
T3 279-457 Sentence denotes It is believed to play a role in myelination and axonal stabilization and, through repulsive properties, may contribute to the lack of regeneration of CNS axons following damage.
T4 458-569 Sentence denotes The contrary functions of the tenascins have been localized to the different structural domains of the protein.
T5 570-727 Sentence denotes However, little is known concerning the influence of the carbohydrate conjugated to the many potential sites for N - and O -glycosylation (10-20% by weight).
T6 728-873 Sentence denotes As a first analytical requirement, we show that >80% of the N -glycans in tenascin-R are neutral and dominated by complex biantennary structures.
T7 874-1047 Sentence denotes These display the "brain-type" characteristics of outer-arm- and core-fucosylation, a bisecting N -acetylglucosamine and, significantly, an abundance of antennae truncation.
T8 1048-1216 Sentence denotes In some structures, truncation resulted in only a single mannose residue remaining on the 3-arm, a particularly unusual consequence of the N -glycan processing pathway.
T9 1217-1323 Sentence denotes In contrast to brain tissue, hybrid and oligomannosidic N -glycans were either absent or in low abundance.
T10 1324-1392 Sentence denotes A high relative abundance of O -linked sialylated glycans was found.
T11 1393-1528 Sentence denotes This was associated with a significant potential for O -linked glycosylation sites and multivalent display of the sialic acid residues.
T12 1529-1637 Sentence denotes These O -glycans were dominated by the disialylated structure, NeuAcalpha2-3Galbeta1-3(NeuAcalpha2-6)GalNAc.
T13 1638-1821 Sentence denotes The possibility that these O -glycans enable tenascin-R to interact in the CNS either with the myelin associated glycoprotein or with sialoadhesin on activated microglia is discussed.

GO-BP

Id Subject Object Predicate Lexical cue
T1 0-13 http://purl.obolibrary.org/obo/GO_0070085 denotes Glycosylation
T2 694-707 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T3 1456-1469 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T4 104-114 http://purl.obolibrary.org/obo/GO_0097503 denotes sialylated
T5 1363-1373 http://purl.obolibrary.org/obo/GO_0097503 denotes sialylated
T6 312-323 http://purl.obolibrary.org/obo/GO_0042552 denotes myelination
T7 1733-1739 http://purl.obolibrary.org/obo/GO_0042552 denotes myelin
T8 414-426 http://purl.obolibrary.org/obo/GO_0031099 denotes regeneration
T9 508-517 http://purl.obolibrary.org/obo/GO_0051179 denotes localized
T10 640-650 http://purl.obolibrary.org/obo/GO_0000746 denotes conjugated
T11 944-956 http://purl.obolibrary.org/obo/GO_0036065 denotes fucosylation
T12 1187-1207 http://purl.obolibrary.org/obo/GO_0016256 denotes N -glycan processing
T13 1187-1207 http://purl.obolibrary.org/obo/GO_0006491 denotes N -glycan processing
T14 1446-1469 http://purl.obolibrary.org/obo/GO_0006493 denotes O -linked glycosylation

GO-MF

Id Subject Object Predicate Lexical cue
T1 197-231 http://purl.obolibrary.org/obo/GO_0005201 denotes extracellular matrix glycoproteins

GO-CC

Id Subject Object Predicate Lexical cue
T1 32-45 http://purl.obolibrary.org/obo/GO_0005576 denotes extracellular
T2 197-210 http://purl.obolibrary.org/obo/GO_0005576 denotes extracellular
T3 32-52 http://purl.obolibrary.org/obo/GO_0031012 denotes extracellular matrix
T4 197-217 http://purl.obolibrary.org/obo/GO_0031012 denotes extracellular matrix
T5 939-943 http://purl.obolibrary.org/obo/GO_0019013 denotes core

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 128-133 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T2 893-898 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T3 1232-1237 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T4 312-323 http://purl.obolibrary.org/obo/UBERON_0000345 denotes myelination
T5 1733-1739 http://purl.obolibrary.org/obo/UBERON_0000345 denotes myelin
T6 930-933 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm
T7 1140-1143 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm
T8 1027-1035 http://purl.obolibrary.org/obo/UBERON_0000972 denotes antennae
T9 1238-1244 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 128-133 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T2 893-898 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T3 1027-1035 http://purl.obolibrary.org/obo/MAT_0000086 denotes antennae
T4 1232-1237 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1238-1244 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
PD-UBERON-AE-B_T2 128-133 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
PD-UBERON-AE-B_T3 893-898 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
PD-UBERON-AE-B_T4 1232-1237 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
PD-UBERON-AE-B_T5 312-323 http://purl.obolibrary.org/obo/UBERON_0000345 denotes myelination
PD-UBERON-AE-B_T6 1733-1739 http://purl.obolibrary.org/obo/UBERON_0000345 denotes myelin
PD-UBERON-AE-B_T7 930-933 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm
PD-UBERON-AE-B_T8 1140-1143 http://purl.obolibrary.org/obo/UBERON_0001460 denotes arm
PD-UBERON-AE-B_T9 1027-1035 http://purl.obolibrary.org/obo/UBERON_0000972 denotes antennae

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 148-157 http://rdf.glycoinfo.org/glycan/G00027MO denotes N-glycans
T2 1187-1196 http://rdf.glycoinfo.org/glycan/G00027MO denotes N -glycan

Lectin

Id Subject Object Predicate Lexical cue
Lectin_T1 1772-1784 https://acgg.asia/db/lfdb/LfDB0072 denotes sialoadhesin

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T18 1630-1636 "http://rdf.glycoinfo.org/glycan/G61406KC" denotes GalNAc
GlycanIUPAC_T1 1630-1636 "http://rdf.glycoinfo.org/glycan/G23425WZ" denotes GalNAc
GlycanIUPAC_T2 1630-1636 "http://rdf.glycoinfo.org/glycan/G02874VH" denotes GalNAc
GlycanIUPAC_T3 1630-1636 "http://rdf.glycoinfo.org/glycan/G99699DW" denotes GalNAc
GlycanIUPAC_T4 1630-1636 "http://rdf.glycoinfo.org/glycan/G22074RM" denotes GalNAc
GlycanIUPAC_T5 1630-1636 "http://rdf.glycoinfo.org/glycan/G48535VZ" denotes GalNAc
GlycanIUPAC_T6 1630-1636 "http://rdf.glycoinfo.org/glycan/G39738WL" denotes GalNAc
GlycanIUPAC_T7 1630-1636 "http://rdf.glycoinfo.org/glycan/G42313WU" denotes GalNAc
GlycanIUPAC_T8 1630-1636 "http://rdf.glycoinfo.org/glycan/G00393CK" denotes GalNAc
GlycanIUPAC_T9 1630-1636 "http://rdf.glycoinfo.org/glycan/G42649EX" denotes GalNAc
GlycanIUPAC_T10 1630-1636 "http://rdf.glycoinfo.org/glycan/G46880SB" denotes GalNAc
GlycanIUPAC_T11 1630-1636 "http://rdf.glycoinfo.org/glycan/G75599IR" denotes GalNAc
GlycanIUPAC_T12 1630-1636 "http://rdf.glycoinfo.org/glycan/G58985MU" denotes GalNAc
GlycanIUPAC_T13 1630-1636 "http://rdf.glycoinfo.org/glycan/G92517PO" denotes GalNAc
GlycanIUPAC_T14 1630-1636 "http://rdf.glycoinfo.org/glycan/G88512YL" denotes GalNAc
GlycanIUPAC_T15 1630-1636 "http://rdf.glycoinfo.org/glycan/G41473NX" denotes GalNAc
GlycanIUPAC_T16 1630-1636 "http://rdf.glycoinfo.org/glycan/G71089RB" denotes GalNAc
GlycanIUPAC_T17 1630-1636 "http://rdf.glycoinfo.org/glycan/G73485GZ" denotes GalNAc
GlycanIUPAC_T19 1630-1636 "http://rdf.glycoinfo.org/glycan/G34412GZ" denotes GalNAc
GlycanIUPAC_T20 1630-1636 "http://rdf.glycoinfo.org/glycan/G67209FP" denotes GalNAc
GlycanIUPAC_T21 1630-1636 "http://rdf.glycoinfo.org/glycan/G61442IL" denotes GalNAc
GlycanIUPAC_T22 1630-1636 "http://rdf.glycoinfo.org/glycan/G93729MV" denotes GalNAc
GlycanIUPAC_T23 1630-1636 "http://rdf.glycoinfo.org/glycan/G92144AE" denotes GalNAc

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 1630-1636 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 128-133 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T2 893-898 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 1027-1035 Body_part denotes antennae http://purl.obolibrary.org/obo/MAT_0000086
T4 1232-1237 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 1630-1636 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 1788-1807 Cell denotes activated microglia http://purl.obolibrary.org/obo/CL:0002629
T2 1798-1807 Cell denotes microglia http://purl.obolibrary.org/obo/CL:0000129

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 32-52 Body_part denotes extracellular matrix http://purl.obolibrary.org/obo/GO_0031012
T2 128-133 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T3 197-217 Body_part denotes extracellular matrix http://purl.obolibrary.org/obo/GO_0031012
T4 893-898 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T5 930-933 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460|http://purl.obolibrary.org/obo/UBERON_0003822
T7 1140-1143 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460|http://purl.obolibrary.org/obo/UBERON_0003822
T9 1232-1237 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T10 1238-1244 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T11 1733-1739 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-158 Sentence denotes Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans.
T2 159-278 Sentence denotes As a member of the tenascin family of extracellular matrix glycoproteins, tenascin-R is located exclusively in the CNS.
T3 279-457 Sentence denotes It is believed to play a role in myelination and axonal stabilization and, through repulsive properties, may contribute to the lack of regeneration of CNS axons following damage.
T4 458-569 Sentence denotes The contrary functions of the tenascins have been localized to the different structural domains of the protein.
T5 570-727 Sentence denotes However, little is known concerning the influence of the carbohydrate conjugated to the many potential sites for N - and O -glycosylation (10-20% by weight).
T6 728-873 Sentence denotes As a first analytical requirement, we show that >80% of the N -glycans in tenascin-R are neutral and dominated by complex biantennary structures.
T7 874-1047 Sentence denotes These display the "brain-type" characteristics of outer-arm- and core-fucosylation, a bisecting N -acetylglucosamine and, significantly, an abundance of antennae truncation.
T8 1048-1216 Sentence denotes In some structures, truncation resulted in only a single mannose residue remaining on the 3-arm, a particularly unusual consequence of the N -glycan processing pathway.
T9 1217-1323 Sentence denotes In contrast to brain tissue, hybrid and oligomannosidic N -glycans were either absent or in low abundance.
T10 1324-1392 Sentence denotes A high relative abundance of O -linked sialylated glycans was found.
T11 1393-1528 Sentence denotes This was associated with a significant potential for O -linked glycosylation sites and multivalent display of the sialic acid residues.
T12 1529-1637 Sentence denotes These O -glycans were dominated by the disialylated structure, NeuAcalpha2-3Galbeta1-3(NeuAcalpha2-6)GalNAc.
T13 1638-1821 Sentence denotes The possibility that these O -glycans enable tenascin-R to interact in the CNS either with the myelin associated glycoprotein or with sialoadhesin on activated microglia is discussed.

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 32-52 Body_part denotes extracellular matrix FMA:9672
T2 128-133 Body_part denotes brain FMA:50801
T3 197-217 Body_part denotes extracellular matrix FMA:9672
T4 893-898 Body_part denotes brain FMA:50801
T5 930-933 Body_part denotes arm FMA:24890
T6 1140-1143 Body_part denotes arm FMA:24890
T7 1232-1237 Body_part denotes brain FMA:50801
T8 1238-1244 Body_part denotes tissue FMA:9637
T9 1798-1807 Body_part denotes microglia FMA:68923

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 128-133 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T2 893-898 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 1027-1035 Body_part denotes antennae http://purl.obolibrary.org/obo/MAT_0000086
T4 1232-1237 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 32-52 Body_part denotes extracellular matrix http://purl.obolibrary.org/obo/GO_0031012
T2 128-133 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T4 197-217 Body_part denotes extracellular matrix http://purl.obolibrary.org/obo/GO_0031012
T5 893-898 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T7 930-933 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460|http://purl.obolibrary.org/obo/UBERON_0003822
T9 1140-1143 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460|http://purl.obolibrary.org/obo/UBERON_0003822
T11 1232-1237 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T13 1238-1244 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T14 1733-1739 Body_part denotes myelin http://purl.obolibrary.org/obo/UBERON_0000345