PubMed:10402173
Annnotations
PMID_GLOBAL
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 86-107 | DiseaseOrPhenotypicFeature | denotes | renal cell carcinomas | 0005086|0005549 |
| T3 | 142-162 | DiseaseOrPhenotypicFeature | denotes | renal cell carcinoma | 0005086|0005549 |
| T5 | 164-167 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T9 | 329-332 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T13 | 387-390 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T17 | 401-404 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T21 | 568-571 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T25 | 933-936 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T29 | 947-950 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T33 | 1148-1151 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T37 | 1154-1157 | DiseaseOrPhenotypicFeature | denotes | can | 0012833 |
| T38 | 1266-1269 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
| T42 | 1325-1328 | DiseaseOrPhenotypicFeature | denotes | RCC | 0005086|0005549|0007763|0044874 |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 142-162 | HP_0005584 | denotes | renal cell carcinoma |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 15-24 | protein | denotes | NF-kappaB |
| T2 | 39-53 | cell_type | denotes | normal T cells |
| T3 | 109-122 | cell_type | denotes | T lymphocytes |
| T4 | 229-249 | protein | denotes | transcription factor |
| T5 | 251-260 | protein | denotes | NF-kappaB |
| T6 | 293-302 | protein | denotes | NF-kappaB |
| T7 | 318-325 | cell_type | denotes | T cells |
| T8 | 438-447 | protein | denotes | NF-kappaB |
| T9 | 463-477 | cell_type | denotes | normal T cells |
| T10 | 506-513 | cell_type | denotes | T cells |
| T11 | 530-536 | protein | denotes | kappaB |
| T12 | 557-564 | cell_type | denotes | T cells |
| T13 | 620-627 | cell_type | denotes | T cells |
| T14 | 696-710 | protein | denotes | RelA/NFkappaB1 |
| T15 | 760-766 | protein | denotes | kappaB |
| T16 | 835-847 | protein | denotes | IkappaBalpha |
| T17 | 920-927 | cell_type | denotes | T cells |
| T18 | 993-997 | protein | denotes | RelA |
| T19 | 1002-1012 | protein | denotes | NF-kappaB1 |
| T20 | 1089-1122 | protein | denotes | RelA/NF-kappaB1 binding complexes |
| T21 | 1168-1182 | cell_type | denotes | normal T cells |
| T22 | 1214-1223 | protein | denotes | NF-kappaB |
| T23 | 1255-1262 | cell_type | denotes | T cells |
| T24 | 1300-1309 | protein | denotes | NF-kappaB |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 39-53 | NP | denotes | normal T cells |
| C2 | 80-107 | NP | denotes | human renal cell carcinomas |
| C5 | 142-168 | NP | denotes | renal cell carcinoma (RCC) |
| C4 | 128-168 | NP | denotes | patients with renal cell carcinoma (RCC) |
| C3 | 109-168 | NP | denotes | T lymphocytes from patients with renal cell carcinoma (RCC) |
| C7 | 225-249 | NP | denotes | the transcription factor |
| C8 | 251-260 | NP | denotes | NF-kappaB |
| C6 | 202-260 | NP | denotes | impaired activation of the transcription factor, NF-kappaB |
| C9 | 293-314 | NP | denotes | NF-kappaB suppression |
| C11 | 329-340 | NP | denotes | RCC patient |
| C10 | 318-340 | NP | denotes | T cells of RCC patient |
| C12 | 387-407 | NP | denotes | RCC explants (RCC-S) |
| C13 | 438-459 | NP | denotes | NF-kappaB suppression |
| C14 | 463-477 | NP | denotes | normal T cells |
| C15 | 478-482 | NP | denotes | that |
| C16 | 498-513 | NP | denotes | patient T cells |
| C18 | 530-553 | NP | denotes | kappaB-binding activity |
| C17 | 515-553 | NP | denotes | The pattern of kappaB-binding activity |
| C20 | 568-579 | NP | denotes | RCC patient |
| C19 | 557-579 | NP | denotes | T cells of RCC patient |
| C21 | 607-611 | NP | denotes | that |
| C22 | 760-783 | NP | denotes | kappaB-binding activity |
| C23 | 933-945 | NP | denotes | RCC patients |
| C24 | 947-952 | NP | denotes | RCC-S |
| C25 | 1030-1035 | NP | denotes | their |
| C26 | 1148-1153 | NP | denotes | RCC-S |
| C27 | 1168-1182 | NP | denotes | normal T cells |
| C29 | 1205-1234 | NP | denotes | impaired NF-kappaB activation |
| C28 | 1183-1234 | NP | denotes | the same phenotype of impaired NF-kappaB activation |
| C30 | 1235-1239 | NP | denotes | that |
| C32 | 1266-1277 | NP | denotes | RCC patient |
| C31 | 1255-1277 | NP | denotes | T cells of RCC patient |
| C33 | 1300-1321 | NP | denotes | NF-kappaB suppression |
| C34 | 1325-1330 | NP | denotes | RCC-S |
| R1 | C5 | C2 | coref-ident | renal cell carcinoma (RCC),human renal cell carcinomas |
| R2 | C8 | C7 | coref-appos | NF-kappaB,the transcription factor |
| R3 | C11 | C4 | coref-ident | RCC patient,patients with renal cell carcinoma (RCC) |
| R4 | C10 | C3 | coref-ident | T cells of RCC patient,T lymphocytes from patients with renal cell carcinoma (RCC) |
| R5 | C13 | C9 | coref-ident | NF-kappaB suppression,NF-kappaB suppression |
| R6 | C15 | C14 | coref-relat | that,normal T cells |
| R7 | C16 | C10 | coref-ident | patient T cells,T cells of RCC patient |
| R8 | C20 | C11 | coref-ident | RCC patient,RCC patient |
| R9 | C19 | C16 | coref-ident | T cells of RCC patient,patient T cells |
| R10 | C21 | C17 | coref-pron | that,The pattern of kappaB-binding activity |
| R11 | C22 | C18 | coref-ident | kappaB-binding activity,kappaB-binding activity |
| R12 | C23 | C20 | coref-ident | RCC patients,RCC patient |
| R13 | C24 | C12 | coref-ident | RCC-S,RCC explants (RCC-S) |
| R14 | C25 | C24 | coref-pron | their,RCC-S |
| R15 | C26 | C24 | coref-ident | RCC-S,RCC-S |
| R16 | C27 | C1 | coref-ident | normal T cells,normal T cells |
| R17 | C29 | C6 | coref-ident | impaired NF-kappaB activation,"impaired activation of the transcription factor, NF-kappaB" |
| R18 | C30 | C28 | coref-relat | that,the same phenotype of impaired NF-kappaB activation |
| R19 | C32 | C23 | coref-ident | RCC patient,RCC patients |
| R20 | C31 | C19 | coref-ident | T cells of RCC patient,T cells of RCC patient |
| R21 | C33 | C13 | coref-ident | NF-kappaB suppression,NF-kappaB suppression |
| R22 | C34 | C26 | coref-ident | RCC-S,RCC-S |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-108 | Sentence | denotes | Suppression of NF-kappaB activation in normal T cells by supernatant fluid from human renal cell carcinomas. |
| S2 | 109-261 | Sentence | denotes | T lymphocytes from patients with renal cell carcinoma (RCC) show reduced immune function and impaired activation of the transcription factor, NF-kappaB. |
| S3 | 262-514 | Sentence | denotes | We determined the mechanism of NF-kappaB suppression in T cells of RCC patient and determined whether supernatant fluid from RCC explants (RCC-S) induced the same phenotype of NF-kappaB suppression in normal T cells that is observed in patient T cells. |
| S4 | 515-660 | Sentence | denotes | The pattern of kappaB-binding activity in T cells of RCC patient was altered as compared to that seen in T cells obtained from normal volunteers. |
| S5 | 661-834 | Sentence | denotes | In some patients, no activation of RelA/NFkappaB1-binding activity was detectable, while in others kappaB-binding activity was modestly induced but the duration was reduced. |
| S6 | 835-946 | Sentence | denotes | IkappaBalpha was degraded normally following stimulation in both normal controls and T cells from RCC patients. |
| S7 | 947-1123 | Sentence | denotes | RCC-S did not alter the cytoplasmic levels of RelA and NF-kappaB1 but did suppress their nuclear localization and inhibited the activation of RelA/NF-kappaB1 binding complexes. |
| S8 | 1124-1278 | Sentence | denotes | These results show that RCC-S can induce in normal T cells the same phenotype of impaired NF-kappaB activation that is detected in T cells of RCC patient. |
| S9 | 1279-1388 | Sentence | denotes | It also appears that NF-kappaB suppression by RCC-S may contribute to the immunosuppression of host immunity. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 15-24 | protein_molecule | denotes | NF-kappaB |
| T2 | 39-53 | cell_type | denotes | normal T cells |
| T3 | 57-74 | other_name | denotes | supernatant fluid |
| T4 | 80-107 | other_name | denotes | human renal cell carcinomas |
| T5 | 109-122 | cell_type | denotes | T lymphocytes |
| T6 | 142-162 | other_name | denotes | renal cell carcinoma |
| T7 | 164-167 | other_name | denotes | RCC |
| T8 | 182-197 | other_name | denotes | immune function |
| T9 | 229-249 | protein_family_or_group | denotes | transcription factor |
| T10 | 251-260 | protein_molecule | denotes | NF-kappaB |
| T11 | 293-302 | protein_molecule | denotes | NF-kappaB |
| T12 | 318-325 | cell_type | denotes | T cells |
| T13 | 329-332 | other_name | denotes | RCC |
| T14 | 387-390 | other_name | denotes | RCC |
| T15 | 401-404 | other_name | denotes | RCC |
| T16 | 438-447 | protein_molecule | denotes | NF-kappaB |
| T17 | 463-469 | cell_type | denotes | normal |
| T18 | 470-477 | cell_type | denotes | T cells |
| T19 | 506-513 | cell_type | denotes | T cells |
| T20 | 530-536 | protein_molecule | denotes | kappaB |
| T21 | 557-564 | cell_type | denotes | T cells |
| T22 | 568-571 | other_name | denotes | RCC |
| T23 | 620-627 | cell_type | denotes | T cells |
| T24 | 696-710 | protein_complex | denotes | RelA/NFkappaB1 |
| T25 | 760-766 | protein_molecule | denotes | kappaB |
| T26 | 835-847 | protein_molecule | denotes | IkappaBalpha |
| T27 | 920-927 | cell_type | denotes | T cells |
| T28 | 933-936 | other_name | denotes | RCC |
| T29 | 947-950 | other_name | denotes | RCC |
| T30 | 993-997 | protein_subunit | denotes | RelA |
| T31 | 1002-1012 | protein_molecule | denotes | NF-kappaB1 |
| T32 | 1036-1056 | other_name | denotes | nuclear localization |
| T33 | 1089-1093 | protein_subunit | denotes | RelA |
| T34 | 1093-1104 | protein_molecule | denotes | /NF-kappaB1 |
| T35 | 1148-1151 | other_name | denotes | RCC |
| T36 | 1168-1174 | cell_type | denotes | normal |
| T37 | 1175-1182 | cell_type | denotes | T cells |
| T38 | 1214-1223 | protein_molecule | denotes | NF-kappaB |
| T39 | 1255-1262 | cell_type | denotes | T cells |
| T40 | 1266-1269 | other_name | denotes | RCC |
| T41 | 1300-1309 | protein_molecule | denotes | NF-kappaB |
| T42 | 1325-1328 | other_name | denotes | RCC |
| T43 | 1353-1370 | other_name | denotes | immunosuppression |
| T44 | 1374-1387 | other_name | denotes | host immunity |