PubMed:10396290
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 25-37 | DNA | denotes | X-chromosome |
| T2 | 58-86 | DNA | denotes | human androgen receptor gene |
| T3 | 88-94 | DNA | denotes | Humara |
| T4 | 401-413 | DNA | denotes | X-chromosome |
| T5 | 640-678 | DNA | denotes | human androgen receptor (HUMARA) locus |
| T6 | 874-880 | DNA | denotes | allele |
| T7 | 882-888 | DNA | denotes | allele |
| T8 | 1157-1163 | DNA | denotes | allele |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 142-177 | NP | denotes | chronic myeloproliferative diseases |
| C2 | 179-201 | NP | denotes | secondary neutrophilia |
| C3 | 207-230 | NP | denotes | reactive thrombocytosis |
| C4 | 232-274 | NP | denotes | Chronic myeloproliferative diseases (MPDs) |
| C5 | 389-452 | NP | denotes | analysis of X-chromosome inactivation (XCI) patterns in females |
| C6 | 503-517 | NP | denotes | this technique |
| C7 | 717-739 | NP | denotes | secondary neutrophilia |
| C8 | 755-778 | NP | denotes | reactive thrombocytosis |
| C10 | 798-810 | NP | denotes | chronic MPDs |
| C9 | 784-810 | NP | denotes | 86 women with chronic MPDs |
| C12 | 1120-1133 | NP | denotes | a chronic MPD |
| C11 | 1103-1133 | NP | denotes | 86 patients with a chronic MPD |
| C13 | 1374-1385 | NP | denotes | chronic MPD |
| R1 | C4 | C1 | coref-ident | Chronic myeloproliferative diseases (MPDs),chronic myeloproliferative diseases |
| R2 | C6 | C5 | coref-ident | this technique,analysis of X-chromosome inactivation (XCI) patterns in females |
| R3 | C7 | C2 | coref-ident | secondary neutrophilia,secondary neutrophilia |
| R4 | C8 | C3 | coref-ident | reactive thrombocytosis,reactive thrombocytosis |
| R5 | C10 | C4 | coref-ident | chronic MPDs,Chronic myeloproliferative diseases (MPDs) |
| R6 | C12 | C10 | coref-ident | a chronic MPD,chronic MPDs |
| R7 | C11 | C9 | coref-ident | 86 patients with a chronic MPD,86 women with chronic MPDs |
| R8 | C13 | C12 | coref-ident | chronic MPD,a chronic MPD |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-96 | Sentence | denotes | Clonality analysis using X-chromosome inactivation at the human androgen receptor gene (Humara). |
| S2 | 97-231 | Sentence | denotes | Evaluation of large cohorts of patients with chronic myeloproliferative diseases, secondary neutrophilia, and reactive thrombocytosis. |
| S3 | 232-349 | Sentence | denotes | Chronic myeloproliferative diseases (MPDs) are not associated with consistent cytogenetic or molecular abnormalities. |
| S4 | 350-493 | Sentence | denotes | Demonstration of clonal cell growth by analysis of X-chromosome inactivation (XCI) patterns in females provides a promising tool for diagnosis. |
| S5 | 494-811 | Sentence | denotes | However, this technique can be complicated by excessive lyonization of normal cells mimicking clonal cell growth: We analyzed XCI patterns at the human androgen receptor (HUMARA) locus in 146 healthy females, 65 women with secondary neutrophilia, 31 women with reactive thrombocytosis, and 86 women with chronic MPDs. |
| S6 | 812-949 | Sentence | denotes | A skewed XCI pattern with greater than 75% amplification of 1 allele (allele ratio > 3:1) was found in 22 (9.1%) of 242 control subjects. |
| S7 | 950-1099 | Sentence | denotes | The incidence of skewing was statistically significantly lower in women younger than 30 years (2/73) compared with women older than 60 years (10/53). |
| S8 | 1100-1273 | Sentence | denotes | Of 86 patients with a chronic MPD, 71 (82%) exhibited an allele ratio greater than 3:1, whereas only 10 (12%) of 86 age-matched control subjects showed a skewed XCI pattern. |
| S9 | 1274-1484 | Sentence | denotes | Although statistical evaluation of the data showed a significant difference between patients with a chronic MPD and control subjects, proof of clonality in individual, especially elderly, patients is difficult. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 25-37 | DNA_molecule | denotes | X-chromosome |
| T2 | 58-86 | DNA_domain_or_region | denotes | human androgen receptor gene |
| T3 | 88-94 | DNA_domain_or_region | denotes | Humara |
| T4 | 142-177 | other_name | denotes | chronic myeloproliferative diseases |
| T5 | 179-201 | other_name | denotes | secondary neutrophilia |
| T6 | 207-230 | other_name | denotes | reactive thrombocytosis |
| T7 | 232-267 | other_name | denotes | Chronic myeloproliferative diseases |
| T8 | 269-273 | other_name | denotes | MPDs |
| T9 | 401-413 | DNA_molecule | denotes | X-chromosome |
| T10 | 588-606 | other_name | denotes | clonal cell growth |
| T11 | 620-632 | other_name | denotes | XCI patterns |
| T12 | 640-678 | DNA_domain_or_region | denotes | human androgen receptor (HUMARA) locus |
| T13 | 686-701 | multi_cell | denotes | healthy females |
| T14 | 706-711 | multi_cell | denotes | women |
| T15 | 717-739 | other_name | denotes | secondary neutrophilia |
| T16 | 744-749 | multi_cell | denotes | women |
| T17 | 755-778 | other_name | denotes | reactive thrombocytosis |
| T18 | 787-792 | multi_cell | denotes | women |
| T19 | 798-805 | other_name | denotes | chronic |
| T20 | 806-810 | other_name | denotes | MPDs |
| T21 | 814-832 | other_name | denotes | skewed XCI pattern |
| T22 | 874-880 | DNA_domain_or_region | denotes | allele |
| T23 | 882-888 | DNA_domain_or_region | denotes | allele |
| T24 | 932-948 | multi_cell | denotes | control subjects |
| T25 | 1016-1021 | multi_cell | denotes | women |
| T26 | 1065-1070 | multi_cell | denotes | women |
| T27 | 1106-1114 | multi_cell | denotes | patients |
| T28 | 1122-1133 | other_name | denotes | chronic MPD |
| T29 | 1157-1163 | DNA_domain_or_region | denotes | allele |
| T30 | 1228-1244 | multi_cell | denotes | control subjects |
| T31 | 1254-1272 | other_name | denotes | skewed XCI pattern |
| T32 | 1358-1366 | multi_cell | denotes | patients |
| T33 | 1374-1385 | other_name | denotes | chronic MPD |
| T34 | 1390-1406 | multi_cell | denotes | control subjects |
| T35 | 1462-1470 | multi_cell | denotes | patients |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 646-663 | gene:367 | denotes | androgen receptor |
| T1 | 727-739 | disease:C3665444 | denotes | neutrophilia |
| T2 | 646-663 | gene:367 | denotes | androgen receptor |
| T3 | 755-778 | disease:C0457506 | denotes | reactive thrombocytosis |
| T4 | 665-671 | gene:367 | denotes | HUMARA |
| T5 | 727-739 | disease:C3665444 | denotes | neutrophilia |
| T6 | 665-671 | gene:367 | denotes | HUMARA |
| T7 | 755-778 | disease:C0457506 | denotes | reactive thrombocytosis |
| R1 | T0 | T1 | associated_with | androgen receptor,neutrophilia |
| R2 | T2 | T3 | associated_with | androgen receptor,reactive thrombocytosis |
| R3 | T4 | T5 | associated_with | HUMARA,neutrophilia |
| R4 | T6 | T7 | associated_with | HUMARA,reactive thrombocytosis |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 764-778 | HP_0001894 | denotes | thrombocytosis |