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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-133 Sentence denotes High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas.
TextSentencer_T2 134-254 Sentence denotes Neuroblastoma (NB) is a common pediatric tumor of neural crest origin that is biologically and clinically heterogeneous.
TextSentencer_T3 255-366 Sentence denotes EPH family receptor tyrosine kinases and ephrin ligands play fundamental roles in neurodevelopmental processes.
TextSentencer_T4 367-531 Sentence denotes Recently, we found that NB cell lines expressed several EPHB and EFNB transcripts, which encode EPHB subgroup receptors and ephrin-B subgroup ligands, respectively.
TextSentencer_T5 532-696 Sentence denotes To explore the role of EPHB receptors and ephrin-B ligands in the biology of NB, we examined the expression of EPHB and EFNB transcripts in 47 primary NB specimens.
TextSentencer_T6 697-873 Sentence denotes Multiple EPHB and EFNB transcripts were expressed in all of the NB tumors examined, suggesting the involvement of these transcripts in modulating the biological behavior of NB.
TextSentencer_T7 874-1077 Sentence denotes Higher levels of EPHB6, EFNB2, and EFNB3 expression were found in low-stage tumors (stage 1, 2, and 4S) than in advanced-stage tumors (stage 3 and 4; P = 0.0013, P = 0.0048, and P = 0.027, respectively).
TextSentencer_T8 1078-1273 Sentence denotes Expression of TrkA, a well-established prognostic marker of favorable NB, was positively correlated with EPHB6, EFNB2, and EFNB3 expression (P < 0.0001, P = 0.0019, and P = 0.0001, respectively).
TextSentencer_T9 1274-1463 Sentence denotes MYCN-amplified tumors expressed lower levels of EPHB6, EFNB2, EFNB3, and TrkA transcripts compared to nonamplified tumors (P = 0.0006, P = 0.0023, P = 0.0048, and P = 0.0001, respectively).
TextSentencer_T10 1464-1671 Sentence denotes These data suggest that high-level expression of EPHB6, EFNB2, and EFNB3 is associated with favorable NB and that low-level expression of EPHB6, EFNB2, and EFNB3 correlates with aggressive MYCN-amplified NB.
TextSentencer_T11 1672-1738 Sentence denotes Thus, EPHB6, EFNB2, and EFNB3 may have biological relevance in NB.
TextSentencer_T12 1739-1841 Sentence denotes Further investigation on the biology of these genes may help provide insight into the treatment of NB.
T1 0-133 Sentence denotes High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas.
T2 134-254 Sentence denotes Neuroblastoma (NB) is a common pediatric tumor of neural crest origin that is biologically and clinically heterogeneous.
T3 255-366 Sentence denotes EPH family receptor tyrosine kinases and ephrin ligands play fundamental roles in neurodevelopmental processes.
T4 367-531 Sentence denotes Recently, we found that NB cell lines expressed several EPHB and EFNB transcripts, which encode EPHB subgroup receptors and ephrin-B subgroup ligands, respectively.
T5 532-696 Sentence denotes To explore the role of EPHB receptors and ephrin-B ligands in the biology of NB, we examined the expression of EPHB and EFNB transcripts in 47 primary NB specimens.
T6 697-873 Sentence denotes Multiple EPHB and EFNB transcripts were expressed in all of the NB tumors examined, suggesting the involvement of these transcripts in modulating the biological behavior of NB.
T7 874-1077 Sentence denotes Higher levels of EPHB6, EFNB2, and EFNB3 expression were found in low-stage tumors (stage 1, 2, and 4S) than in advanced-stage tumors (stage 3 and 4; P = 0.0013, P = 0.0048, and P = 0.027, respectively).
T8 1078-1273 Sentence denotes Expression of TrkA, a well-established prognostic marker of favorable NB, was positively correlated with EPHB6, EFNB2, and EFNB3 expression (P < 0.0001, P = 0.0019, and P = 0.0001, respectively).
T9 1274-1463 Sentence denotes MYCN-amplified tumors expressed lower levels of EPHB6, EFNB2, EFNB3, and TrkA transcripts compared to nonamplified tumors (P = 0.0006, P = 0.0023, P = 0.0048, and P = 0.0001, respectively).
T10 1464-1671 Sentence denotes These data suggest that high-level expression of EPHB6, EFNB2, and EFNB3 is associated with favorable NB and that low-level expression of EPHB6, EFNB2, and EFNB3 correlates with aggressive MYCN-amplified NB.
T11 1672-1738 Sentence denotes Thus, EPHB6, EFNB2, and EFNB3 may have biological relevance in NB.
T12 1739-1841 Sentence denotes Further investigation on the biology of these genes may help provide insight into the treatment of NB.

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
10389937-0#32#37#gene1948 32-37 gene1948 denotes EFNB2
10389937-0#43#48#gene1949 43-48 gene1949 denotes EFNB3
10389937-0#118#132#diseaseC0027819 118-132 diseaseC0027819 denotes neuroblastomas
10389937-10#24#29#gene1949 1696-1701 gene1949 denotes EFNB3
10389937-10#63#65#diseaseC0700095 1735-1737 diseaseC0700095 denotes NB
10389937-9#49#54#gene2051 1513-1518 gene2051 denotes EPHB6
10389937-9#56#61#gene1948 1520-1525 gene1948 denotes EFNB2
10389937-9#138#143#gene2051 1602-1607 gene2051 denotes EPHB6
10389937-9#145#150#gene1948 1609-1614 gene1948 denotes EFNB2
10389937-9#189#193#gene4613 1653-1657 gene4613 denotes MYCN
10389937-9#204#206#diseaseC0700095 1668-1670 diseaseC0700095 denotes NB
10389937-9#204#206#diseaseC0027819 1668-1670 diseaseC0027819 denotes NB
10389937-9#102#104#diseaseC0700095 1566-1568 diseaseC0700095 denotes NB
10389937-9#204#206#diseaseC0700095 1668-1670 diseaseC0700095 denotes NB
10389937-9#102#104#diseaseC0700095 1566-1568 diseaseC0700095 denotes NB
10389937-9#102#104#diseaseC0027819 1566-1568 diseaseC0027819 denotes NB
10389937-9#204#206#diseaseC0700095 1668-1670 diseaseC0700095 denotes NB
10389937-9#204#206#diseaseC0027819 1668-1670 diseaseC0027819 denotes NB
32#37#gene1948118#132#diseaseC0027819 10389937-0#32#37#gene1948 10389937-0#118#132#diseaseC0027819 associated_with EFNB2,neuroblastomas
43#48#gene1949118#132#diseaseC0027819 10389937-0#43#48#gene1949 10389937-0#118#132#diseaseC0027819 associated_with EFNB3,neuroblastomas
24#29#gene194963#65#diseaseC0700095 10389937-10#24#29#gene1949 10389937-10#63#65#diseaseC0700095 associated_with EFNB3,NB
49#54#gene2051204#206#diseaseC0700095 10389937-9#49#54#gene2051 10389937-9#204#206#diseaseC0700095 associated_with EPHB6,NB
49#54#gene2051204#206#diseaseC0027819 10389937-9#49#54#gene2051 10389937-9#204#206#diseaseC0027819 associated_with EPHB6,NB
49#54#gene2051102#104#diseaseC0700095 10389937-9#49#54#gene2051 10389937-9#102#104#diseaseC0700095 associated_with EPHB6,NB
49#54#gene2051204#206#diseaseC0700095 10389937-9#49#54#gene2051 10389937-9#204#206#diseaseC0700095 associated_with EPHB6,NB
49#54#gene2051102#104#diseaseC0700095 10389937-9#49#54#gene2051 10389937-9#102#104#diseaseC0700095 associated_with EPHB6,NB
49#54#gene2051102#104#diseaseC0027819 10389937-9#49#54#gene2051 10389937-9#102#104#diseaseC0027819 associated_with EPHB6,NB
49#54#gene2051204#206#diseaseC0700095 10389937-9#49#54#gene2051 10389937-9#204#206#diseaseC0700095 associated_with EPHB6,NB
49#54#gene2051204#206#diseaseC0027819 10389937-9#49#54#gene2051 10389937-9#204#206#diseaseC0027819 associated_with EPHB6,NB
56#61#gene1948204#206#diseaseC0700095 10389937-9#56#61#gene1948 10389937-9#204#206#diseaseC0700095 associated_with EFNB2,NB
56#61#gene1948204#206#diseaseC0027819 10389937-9#56#61#gene1948 10389937-9#204#206#diseaseC0027819 associated_with EFNB2,NB
56#61#gene1948102#104#diseaseC0700095 10389937-9#56#61#gene1948 10389937-9#102#104#diseaseC0700095 associated_with EFNB2,NB
56#61#gene1948204#206#diseaseC0700095 10389937-9#56#61#gene1948 10389937-9#204#206#diseaseC0700095 associated_with EFNB2,NB
56#61#gene1948102#104#diseaseC0700095 10389937-9#56#61#gene1948 10389937-9#102#104#diseaseC0700095 associated_with EFNB2,NB
56#61#gene1948102#104#diseaseC0027819 10389937-9#56#61#gene1948 10389937-9#102#104#diseaseC0027819 associated_with EFNB2,NB
56#61#gene1948204#206#diseaseC0700095 10389937-9#56#61#gene1948 10389937-9#204#206#diseaseC0700095 associated_with EFNB2,NB
56#61#gene1948204#206#diseaseC0027819 10389937-9#56#61#gene1948 10389937-9#204#206#diseaseC0027819 associated_with EFNB2,NB
138#143#gene2051204#206#diseaseC0700095 10389937-9#138#143#gene2051 10389937-9#204#206#diseaseC0700095 associated_with EPHB6,NB
138#143#gene2051204#206#diseaseC0027819 10389937-9#138#143#gene2051 10389937-9#204#206#diseaseC0027819 associated_with EPHB6,NB
138#143#gene2051102#104#diseaseC0700095 10389937-9#138#143#gene2051 10389937-9#102#104#diseaseC0700095 associated_with EPHB6,NB
138#143#gene2051204#206#diseaseC0700095 10389937-9#138#143#gene2051 10389937-9#204#206#diseaseC0700095 associated_with EPHB6,NB
138#143#gene2051102#104#diseaseC0700095 10389937-9#138#143#gene2051 10389937-9#102#104#diseaseC0700095 associated_with EPHB6,NB
138#143#gene2051102#104#diseaseC0027819 10389937-9#138#143#gene2051 10389937-9#102#104#diseaseC0027819 associated_with EPHB6,NB
138#143#gene2051204#206#diseaseC0700095 10389937-9#138#143#gene2051 10389937-9#204#206#diseaseC0700095 associated_with EPHB6,NB
138#143#gene2051204#206#diseaseC0027819 10389937-9#138#143#gene2051 10389937-9#204#206#diseaseC0027819 associated_with EPHB6,NB
145#150#gene1948204#206#diseaseC0700095 10389937-9#145#150#gene1948 10389937-9#204#206#diseaseC0700095 associated_with EFNB2,NB
145#150#gene1948204#206#diseaseC0027819 10389937-9#145#150#gene1948 10389937-9#204#206#diseaseC0027819 associated_with EFNB2,NB
145#150#gene1948102#104#diseaseC0700095 10389937-9#145#150#gene1948 10389937-9#102#104#diseaseC0700095 associated_with EFNB2,NB
145#150#gene1948204#206#diseaseC0700095 10389937-9#145#150#gene1948 10389937-9#204#206#diseaseC0700095 associated_with EFNB2,NB
145#150#gene1948102#104#diseaseC0700095 10389937-9#145#150#gene1948 10389937-9#102#104#diseaseC0700095 associated_with EFNB2,NB
145#150#gene1948102#104#diseaseC0027819 10389937-9#145#150#gene1948 10389937-9#102#104#diseaseC0027819 associated_with EFNB2,NB
145#150#gene1948204#206#diseaseC0700095 10389937-9#145#150#gene1948 10389937-9#204#206#diseaseC0700095 associated_with EFNB2,NB
145#150#gene1948204#206#diseaseC0027819 10389937-9#145#150#gene1948 10389937-9#204#206#diseaseC0027819 associated_with EFNB2,NB
189#193#gene4613204#206#diseaseC0700095 10389937-9#189#193#gene4613 10389937-9#204#206#diseaseC0700095 associated_with MYCN,NB
189#193#gene4613204#206#diseaseC0027819 10389937-9#189#193#gene4613 10389937-9#204#206#diseaseC0027819 associated_with MYCN,NB
189#193#gene4613102#104#diseaseC0700095 10389937-9#189#193#gene4613 10389937-9#102#104#diseaseC0700095 associated_with MYCN,NB
189#193#gene4613204#206#diseaseC0700095 10389937-9#189#193#gene4613 10389937-9#204#206#diseaseC0700095 associated_with MYCN,NB
189#193#gene4613102#104#diseaseC0700095 10389937-9#189#193#gene4613 10389937-9#102#104#diseaseC0700095 associated_with MYCN,NB
189#193#gene4613102#104#diseaseC0027819 10389937-9#189#193#gene4613 10389937-9#102#104#diseaseC0027819 associated_with MYCN,NB
189#193#gene4613204#206#diseaseC0700095 10389937-9#189#193#gene4613 10389937-9#204#206#diseaseC0700095 associated_with MYCN,NB
189#193#gene4613204#206#diseaseC0027819 10389937-9#189#193#gene4613 10389937-9#204#206#diseaseC0027819 associated_with MYCN,NB

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2324 1668-1670 disease:C0700095 denotes NB
T2325 1520-1525 gene:1948 denotes EFNB2
T2326 1566-1568 disease:C0700095 denotes NB
T2327 1602-1607 gene:2051 denotes EPHB6
T2328 1609-1614 gene:1948 denotes EFNB2
T2329 1653-1657 gene:4613 denotes MYCN
T2323 1513-1518 gene:2051 denotes EPHB6
R1 T2323 T2324 associated_with EPHB6,NB
R2 T2323 T2324 associated_with EPHB6,NB
R3 T2325 T2326 associated_with EFNB2,NB
R4 T2325 T2324 associated_with EFNB2,NB
R5 T2327 T2326 associated_with EPHB6,NB
R6 T2327 T2326 associated_with EPHB6,NB
R7 T2328 T2324 associated_with EFNB2,NB
R8 T2329 T2324 associated_with MYCN,NB
R9 T2329 T2324 associated_with MYCN,NB

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 184-196 http://purl.obolibrary.org/obo/UBERON_0002342 denotes neural crest
PD-UBERON-AE-B_T2 191-196 http://purl.obolibrary.org/obo/UBERON_4200133 denotes crest

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 184-196 http://purl.obolibrary.org/obo/UBERON_0002342 denotes neural crest
PD-UBERON-AE-B_T2 191-196 http://purl.obolibrary.org/obo/UBERON_4200133 denotes crest

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1696-1701 gene:1949 denotes EFNB3
T1 1735-1737 disease:C0700095 denotes NB
T2 1696-1701 gene:1949 denotes EFNB3
T3 1735-1737 disease:C0027819 denotes NB
R1 T0 T1 associated_with EFNB3,NB
R2 T2 T3 associated_with EFNB3,NB

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 134-147 HP_0003006 denotes Neuroblastoma
T2 175-180 HP_0002664 denotes tumor
T3 764-770 HP_0002664 denotes tumors
T4 950-956 HP_0002664 denotes tumors
T5 1001-1007 HP_0002664 denotes tumors
T6 1289-1295 HP_0002664 denotes tumors
T7 1389-1395 HP_0002664 denotes tumors
T8 1642-1652 HP_0000718 denotes aggressive