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PubMed:10386895 JSONTXT

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CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 693-705 Cell denotes erythrocytes http://purl.obolibrary.org/obo/CL:0000232

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 190-196 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T2 202-208 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T3 215-221 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T4 237-243 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T5 816-822 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY
T6 1084-1090 Glycan_Motif denotes Neu5Ac https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-115 Sentence denotes Synthetic sialylphosphatidylethanolamine derivatives bind to human influenza A viruses and inhibit viral infection.
TextSentencer_T2 116-256 Sentence denotes We synthesized the sialylphosphatidylethanolamine (sialyl PE) derivatives Neu5Ac-PE, (Neu5Ac)2-PE, Neu5Ac-PE (amide) and Neu5Ac-PE (methyl).
TextSentencer_T3 257-448 Sentence denotes We examined the anti-viral effects of the derivatives on human influenza A virus infection by ELISA/virus-binding, hemagglutination inhibition, hemolysis inhibition and neutralization assays.
TextSentencer_T4 449-620 Sentence denotes The sialyl PE derivatives that we examined bound to A/Aichi/2/68, A/Singapore/1/57 and A/Memphis/1/71 strains of H3N2 subtype, but not to A/PR/8/34 strain of H1N1 subtype.
TextSentencer_T5 621-783 Sentence denotes The derivatives inhibited viral hemagglutination and hemolysis of human erythrocytes with A/Aichi/2/68 and A/Singapore/1/57 (H3N2), but not with A/PR/8/34 (H1N1).
TextSentencer_T6 784-917 Sentence denotes The inhibitory activity of the (Neu5Ac)2-PE derivative was the strongest of all sialyl PE derivatives (IC50, 35 microM to 40 microM).
TextSentencer_T7 918-999 Sentence denotes Sialyl PE derivatives also inhibited the infection of A/Aichi/2/68 in MDCK cells.
TextSentencer_T8 1000-1074 Sentence denotes Complete inhibition was observed at a concentration between 0.3 to 1.3 mM.
TextSentencer_T9 1075-1133 Sentence denotes IC50 of (Neu5Ac)2-PE was 15 microM in A/Aichi/2/68 strain.
TextSentencer_T10 1134-1267 Sentence denotes Taken together, the synthetic sialyl PE derivatives may be effective reagents against infection of some types of influenza A viruses.
T1 0-115 Sentence denotes Synthetic sialylphosphatidylethanolamine derivatives bind to human influenza A viruses and inhibit viral infection.
T2 116-256 Sentence denotes We synthesized the sialylphosphatidylethanolamine (sialyl PE) derivatives Neu5Ac-PE, (Neu5Ac)2-PE, Neu5Ac-PE (amide) and Neu5Ac-PE (methyl).
T3 257-448 Sentence denotes We examined the anti-viral effects of the derivatives on human influenza A virus infection by ELISA/virus-binding, hemagglutination inhibition, hemolysis inhibition and neutralization assays.
T4 449-620 Sentence denotes The sialyl PE derivatives that we examined bound to A/Aichi/2/68, A/Singapore/1/57 and A/Memphis/1/71 strains of H3N2 subtype, but not to A/PR/8/34 strain of H1N1 subtype.
T5 621-783 Sentence denotes The derivatives inhibited viral hemagglutination and hemolysis of human erythrocytes with A/Aichi/2/68 and A/Singapore/1/57 (H3N2), but not with A/PR/8/34 (H1N1).
T6 784-917 Sentence denotes The inhibitory activity of the (Neu5Ac)2-PE derivative was the strongest of all sialyl PE derivatives (IC50, 35 microM to 40 microM).
T7 918-999 Sentence denotes Sialyl PE derivatives also inhibited the infection of A/Aichi/2/68 in MDCK cells.
T8 1000-1074 Sentence denotes Complete inhibition was observed at a concentration between 0.3 to 1.3 mM.
T9 1075-1133 Sentence denotes IC50 of (Neu5Ac)2-PE was 15 microM in A/Aichi/2/68 strain.
T10 1134-1267 Sentence denotes Taken together, the synthetic sialyl PE derivatives may be effective reagents against infection of some types of influenza A viruses.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 190-196 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T2 202-208 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T3 215-221 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T4 237-243 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T5 816-822 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac
T6 1084-1090 https://glytoucan.org/Structures/Glycans/G81533KY denotes Neu5Ac

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 693-705 HP_0001901 denotes erythrocytes

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 190-196 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2 202-208 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T3 215-221 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T4 237-243 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T5 816-822 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T6 1084-1090 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 67-76 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T2 99-114 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T3 320-329 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T4 332-347 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T5 959-968 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 1220-1229 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 1247-1256 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 190-196 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T2 202-208 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T3 215-221 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T4 237-243 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T5 816-822 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR
T6 1084-1090 Glycan denotes Neu5Ac https://api.glycosmos.org/wurcs2image/latest/png/binary/G76685HR

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 693-705 Cell denotes erythrocytes http://purl.obolibrary.org/obo/CL:0000232

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 693-705 Body_part denotes erythrocytes http://purl.obolibrary.org/obo/CL_0000232

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 67-76 Disease denotes influenza MONDO:0005812
T2 99-114 Disease denotes viral infection MONDO:0005108
T3 320-329 Disease denotes influenza MONDO:0005812
T4 332-347 Disease denotes virus infection MONDO:0005108
T5 959-968 Disease denotes infection MONDO:0005550
T6 1220-1229 Disease denotes infection MONDO:0005550
T7 1247-1256 Disease denotes influenza MONDO:0005812

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 61-66 Organism denotes human 9606
T2 67-86 Organism denotes influenza A viruses 11320
T3 314-319 Organism denotes human 9606
T4 320-337 Organism denotes influenza A virus 11320
T5 538-545 Organism denotes Memphis 127271
T6 687-692 Organism denotes human 9606
T7 1247-1266 Organism denotes influenza A viruses 11320

IAV-Glycan_IAV_human_2

Id Subject Object Predicate Lexical cue
T1 562-566 H3N2 denotes H3N2
T2 567-574 subtype denotes subtype
T3 607-611 H1N1 denotes H1N1
T4 612-619 subtype denotes subtype
T5 746-750 H3N2 denotes H3N2
T6 777-781 H1N1 denotes H1N1

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-115 Sentence denotes Synthetic sialylphosphatidylethanolamine derivatives bind to human influenza A viruses and inhibit viral infection.
T2 116-256 Sentence denotes We synthesized the sialylphosphatidylethanolamine (sialyl PE) derivatives Neu5Ac-PE, (Neu5Ac)2-PE, Neu5Ac-PE (amide) and Neu5Ac-PE (methyl).
T3 257-448 Sentence denotes We examined the anti-viral effects of the derivatives on human influenza A virus infection by ELISA/virus-binding, hemagglutination inhibition, hemolysis inhibition and neutralization assays.
T4 449-620 Sentence denotes The sialyl PE derivatives that we examined bound to A/Aichi/2/68, A/Singapore/1/57 and A/Memphis/1/71 strains of H3N2 subtype, but not to A/PR/8/34 strain of H1N1 subtype.
T5 621-783 Sentence denotes The derivatives inhibited viral hemagglutination and hemolysis of human erythrocytes with A/Aichi/2/68 and A/Singapore/1/57 (H3N2), but not with A/PR/8/34 (H1N1).
T6 784-917 Sentence denotes The inhibitory activity of the (Neu5Ac)2-PE derivative was the strongest of all sialyl PE derivatives (IC50, 35 microM to 40 microM).
T7 918-999 Sentence denotes Sialyl PE derivatives also inhibited the infection of A/Aichi/2/68 in MDCK cells.
T8 1000-1074 Sentence denotes Complete inhibition was observed at a concentration between 0.3 to 1.3 mM.
T9 1075-1133 Sentence denotes IC50 of (Neu5Ac)2-PE was 15 microM in A/Aichi/2/68 strain.
T10 1134-1267 Sentence denotes Taken together, the synthetic sialyl PE derivatives may be effective reagents against infection of some types of influenza A viruses.

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 693-705 Body_part denotes erythrocytes FMA:62845

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 67-86 OrganismTaxon denotes influenza A viruses 11320
T2 320-337 OrganismTaxon denotes influenza A virus 11320
T3 538-545 OrganismTaxon denotes Memphis 127271
T4 687-692 OrganismTaxon denotes human 9606
T5 1247-1266 OrganismTaxon denotes influenza A viruses 11320

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 693-705 Body_part denotes erythrocytes http://purl.obolibrary.org/obo/CL_0000232