PubMed:10386598
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10386598","sourcedb":"PubMed","sourceid":"10386598","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10386598","text":"Alpha1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX.\nThe amino acid sequence of Fuc-TIX is very highly conserved between mouse and human. The number of non-synonymous nucleotide substitutions of the Fuc-TIX gene between human and mouse was strikingly low, and almost equivalent to that of the alpha-actin gene. This indicates that Fuc-TIX is under a strong selective pressure of preservation during evolution. The human Fuc-TIX (hFuc-TIX) showed a unique characteristics, i.e. hFuc-TIX was not activated by Mn2+ and Co2+, whereas hFuc-TIV and hFuc-TVI were activated by the cations. The hFuc-TIX transcripts were abundantly expressed in brain and stomach, and interestingly were detected in spleen and peripheral blood leukocytes.","tracks":[{"project":"ggdb-test","denotations":[{"id":"T1","span":{"begin":32,"end":39},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T2","span":{"begin":160,"end":167},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T3","span":{"begin":196,"end":203},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T4","span":{"begin":315,"end":322},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T5","span":{"begin":447,"end":454},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T6","span":{"begin":536,"end":543},"obj":"https://acgg.asia/db/ggdb/info/gg008"}],"attributes":[{"subj":"T1","pred":"source","obj":"ggdb-test"},{"subj":"T2","pred":"source","obj":"ggdb-test"},{"subj":"T3","pred":"source","obj":"ggdb-test"},{"subj":"T4","pred":"source","obj":"ggdb-test"},{"subj":"T5","pred":"source","obj":"ggdb-test"},{"subj":"T6","pred":"source","obj":"ggdb-test"}]},{"project":"GGDB-2020","denotations":[{"id":"T1","span":{"begin":32,"end":39},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T2","span":{"begin":160,"end":167},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T3","span":{"begin":196,"end":203},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T4","span":{"begin":315,"end":322},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T5","span":{"begin":447,"end":454},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"T6","span":{"begin":536,"end":543},"obj":"https://acgg.asia/db/ggdb/info/gg008"}],"attributes":[{"subj":"T1","pred":"source","obj":"GGDB-2020"},{"subj":"T2","pred":"source","obj":"GGDB-2020"},{"subj":"T3","pred":"source","obj":"GGDB-2020"},{"subj":"T4","pred":"source","obj":"GGDB-2020"},{"subj":"T5","pred":"source","obj":"GGDB-2020"},{"subj":"T6","pred":"source","obj":"GGDB-2020"}]},{"project":"glycogenes","denotations":[{"id":"PD-GlycoGenes20190927-B_T1","span":{"begin":32,"end":39},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"PD-GlycoGenes20190927-B_T2","span":{"begin":160,"end":167},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"PD-GlycoGenes20190927-B_T3","span":{"begin":196,"end":203},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"PD-GlycoGenes20190927-B_T4","span":{"begin":315,"end":322},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"PD-GlycoGenes20190927-B_T5","span":{"begin":447,"end":454},"obj":"https://acgg.asia/db/ggdb/info/gg008"},{"id":"PD-GlycoGenes20190927-B_T6","span":{"begin":536,"end":543},"obj":"https://acgg.asia/db/ggdb/info/gg008"}],"attributes":[{"subj":"PD-GlycoGenes20190927-B_T1","pred":"source","obj":"glycogenes"},{"subj":"PD-GlycoGenes20190927-B_T2","pred":"source","obj":"glycogenes"},{"subj":"PD-GlycoGenes20190927-B_T3","pred":"source","obj":"glycogenes"},{"subj":"PD-GlycoGenes20190927-B_T4","pred":"source","obj":"glycogenes"},{"subj":"PD-GlycoGenes20190927-B_T5","pred":"source","obj":"glycogenes"},{"subj":"PD-GlycoGenes20190927-B_T6","pred":"source","obj":"glycogenes"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"ggdb-test","color":"#a9ec93","default":true},{"id":"GGDB-2020","color":"#ec93c3"},{"id":"glycogenes","color":"#93ddec"}]}]}}