PubMed:10383397
Annnotations
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-105 | Sentence | denotes | 3-deazaadenosine, a S-adenosylhomocysteine hydrolase inhibitor, has dual effects on NF-kappaB regulation. |
| T2 | 106-197 | Sentence | denotes | Inhibition of NF-kappaB transcriptional activity and promotion of IkappaBalpha degradation. |
| T3 | 198-469 | Sentence | denotes | Previously we reported that 3-deazaadenosine (DZA), a potent inhibitor and substrate for S-adenosylhomocysteine hydrolase inhibits bacterial lipopolysaccharide-induced transcription of tumor necrosis factor-alpha and interleukin-1beta in mouse macrophage RAW 264.7 cells. |
| T4 | 470-567 | Sentence | denotes | In this study, we demonstrate the effects of DZA on nuclear factor-kappaB (NF-kappaB) regulation. |
| T5 | 568-748 | Sentence | denotes | DZA inhibits the transcriptional activity of NF-kappaB through the hindrance of p65 (Rel-A) phosphorylation without reduction of its nuclear translocation and DNA binding activity. |
| T6 | 749-863 | Sentence | denotes | The inhibitory effect of DZA on NF-kappaB transcriptional activity is potentiated by the addition of homocysteine. |
| T7 | 864-1102 | Sentence | denotes | Taken together, DZA promotes the proteolytic degradation of IkappaBalpha, but not IkappaBbeta, resulting in an increase of DNA binding activity of NF-kappaB in the nucleus in the absence of its transcriptional activity in RAW 264.7 cells. |
| T8 | 1103-1243 | Sentence | denotes | The reduction of IkappaBalpha by DZA is neither involved in IkappaB kinase complex activation nor modulated by the addition of homocysteine. |
| T9 | 1244-1479 | Sentence | denotes | This study strongly suggests that DZA may be a potent drug for the treatment of diseases in which NF-kappaB plays a central pathogenic role, as well as a useful tool for studying the regulation and physiological functions of NF-kappaB. |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 20-52 | protein | denotes | S-adenosylhomocysteine hydrolase |
| T2 | 84-93 | protein | denotes | NF-kappaB |
| T3 | 120-129 | protein | denotes | NF-kappaB |
| T4 | 172-184 | protein | denotes | IkappaBalpha |
| T5 | 287-319 | protein | denotes | S-adenosylhomocysteine hydrolase |
| T6 | 383-410 | protein | denotes | tumor necrosis factor-alpha |
| T7 | 415-432 | protein | denotes | interleukin-1beta |
| T8 | 436-468 | cell_line | denotes | mouse macrophage RAW 264.7 cells |
| T9 | 522-543 | protein | denotes | nuclear factor-kappaB |
| T10 | 545-554 | protein | denotes | NF-kappaB |
| T11 | 613-622 | protein | denotes | NF-kappaB |
| T12 | 648-651 | protein | denotes | p65 |
| T13 | 653-658 | protein | denotes | Rel-A |
| T14 | 781-790 | protein | denotes | NF-kappaB |
| T15 | 924-936 | protein | denotes | IkappaBalpha |
| T16 | 946-957 | protein | denotes | IkappaBbeta |
| T17 | 1011-1020 | protein | denotes | NF-kappaB |
| T18 | 1086-1101 | cell_line | denotes | RAW 264.7 cells |
| T19 | 1120-1132 | protein | denotes | IkappaBalpha |
| T20 | 1163-1185 | protein | denotes | IkappaB kinase complex |
| T21 | 1342-1351 | protein | denotes | NF-kappaB |
| T22 | 1469-1478 | protein | denotes | NF-kappaB |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-16 | NP | denotes | 3-deazaadenosine |
| C2 | 18-62 | NP | denotes | a S-adenosylhomocysteine hydrolase inhibitor |
| C3 | 84-104 | NP | denotes | NF-kappaB regulation |
| C4 | 120-154 | NP | denotes | NF-kappaB transcriptional activity |
| C5 | 226-248 | NP | denotes | 3-deazaadenosine (DZA) |
| C6 | 250-319 | NP | denotes | a potent inhibitor and substrate for S-adenosylhomocysteine hydrolase |
| C7 | 436-468 | NP | denotes | mouse macrophage RAW 264.7 cells |
| C8 | 515-518 | NP | denotes | DZA |
| C9 | 522-566 | NP | denotes | nuclear factor-kappaB (NF-kappaB) regulation |
| C10 | 568-571 | NP | denotes | DZA |
| C12 | 613-622 | NP | denotes | NF-kappaB |
| C11 | 581-622 | NP | denotes | the transcriptional activity of NF-kappaB |
| C13 | 697-700 | NP | denotes | its |
| C14 | 774-777 | NP | denotes | DZA |
| C15 | 781-815 | NP | denotes | NF-kappaB transcriptional activity |
| C16 | 834-862 | NP | denotes | the addition of homocysteine |
| C17 | 880-883 | NP | denotes | DZA |
| C18 | 924-936 | NP | denotes | IkappaBalpha |
| C19 | 1011-1020 | NP | denotes | NF-kappaB |
| C21 | 1054-1057 | NP | denotes | its |
| C20 | 1054-1082 | NP | denotes | its transcriptional activity |
| C22 | 1086-1101 | NP | denotes | RAW 264.7 cells |
| C23 | 1120-1132 | NP | denotes | IkappaBalpha |
| C24 | 1136-1139 | NP | denotes | DZA |
| C25 | 1214-1242 | NP | denotes | the addition of homocysteine |
| C26 | 1278-1281 | NP | denotes | DZA |
| C27 | 1307-1332 | NP | denotes | the treatment of diseases |
| C28 | 1336-1341 | NP | denotes | which |
| C29 | 1342-1351 | NP | denotes | NF-kappaB |
| C30 | 1469-1478 | NP | denotes | NF-kappaB |
| R1 | C2 | C1 | coref-appos | a S-adenosylhomocysteine hydrolase inhibitor,3-deazaadenosine |
| R2 | C5 | C1 | coref-ident | 3-deazaadenosine (DZA),3-deazaadenosine |
| R3 | C6 | C5 | coref-appos | a potent inhibitor and substrate for S-adenosylhomocysteine hydrolase,3-deazaadenosine (DZA) |
| R4 | C8 | C5 | coref-ident | DZA,3-deazaadenosine (DZA) |
| R5 | C9 | C3 | coref-ident | nuclear factor-kappaB (NF-kappaB) regulation,NF-kappaB regulation |
| R6 | C10 | C8 | coref-ident | DZA,DZA |
| R7 | C11 | C4 | coref-ident | the transcriptional activity of NF-kappaB,NF-kappaB transcriptional activity |
| R8 | C13 | C12 | coref-pron | its,NF-kappaB |
| R9 | C14 | C10 | coref-ident | DZA,DZA |
| R10 | C15 | C11 | coref-ident | NF-kappaB transcriptional activity,the transcriptional activity of NF-kappaB |
| R11 | C17 | C14 | coref-ident | DZA,DZA |
| R12 | C19 | C12 | coref-ident | NF-kappaB,NF-kappaB |
| R13 | C21 | C19 | coref-pron | its,NF-kappaB |
| R14 | C20 | C15 | coref-ident | its transcriptional activity,NF-kappaB transcriptional activity |
| R15 | C22 | C7 | coref-ident | RAW 264.7 cells,mouse macrophage RAW 264.7 cells |
| R16 | C23 | C18 | coref-ident | IkappaBalpha,IkappaBalpha |
| R17 | C24 | C17 | coref-ident | DZA,DZA |
| R18 | C25 | C16 | coref-ident | the addition of homocysteine,the addition of homocysteine |
| R19 | C26 | C24 | coref-ident | DZA,DZA |
| R20 | C28 | C27 | coref-relat | which,the treatment of diseases |
| R21 | C29 | C19 | coref-ident | NF-kappaB,NF-kappaB |
| R22 | C30 | C29 | coref-ident | NF-kappaB,NF-kappaB |
semrep-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| E1-ti-1 | 0-16 | cui:C0047329 | denotes | 3-deazaadenosine |
| E2-ti-1 | 20-52 | cui:C0050795 | denotes | S-adenosylhomocysteine hydrolase |
| E3-ti-1 | 53-62 | cui:C0243077 | denotes | inhibitor |
| E4-ti-1 | 73-80 | cui:C1280500 | denotes | effects |
| E5-ti-1 | 84-93 | cui:C0521447 | denotes | NF-kappaB |
| E6-ti-1 | 84-93 | cui:C1521761 | denotes | NF-kappaB |
| E7-ti-1 | 94-104 | cui:C0851285 | denotes | regulation |
| E1-ti-2 | 120-129 | cui:C0521447 | denotes | NF-kappaB |
| E2-ti-2 | 120-129 | cui:C1521761 | denotes | NF-kappaB |
| E3-ti-2 | 130-145 | cui:C0040649 | denotes | transcriptional |
| E4-ti-2 | 146-154 | cui:C0439167 | denotes | activity |
| E5-ti-2 | 159-168 | cui:C0033414 | denotes | promotion |
| E6-ti-2 | 172-184 | cui:C0126732 | denotes | IkappaBalpha |
| E7-ti-2 | 185-196 | cui:C0243125 | denotes | degradation |
| T1 | 106-116 | DISRUPTS | denotes | Inhibition |
| E1-ab-1 | 226-242 | cui:C0047329 | denotes | 3-deazaadenosine |
| E2-ab-1 | 252-258 | cui:C0237399 | denotes | potent |
| E3-ab-1 | 259-268 | cui:C0243077 | denotes | inhibitor |
| E4-ab-1 | 287-319 | cui:C0050795 | denotes | S-adenosylhomocysteine hydrolase |
| E5-ab-1 | 329-338 | cui:C0521009 | denotes | bacterial |
| E6-ab-1 | 339-357 | cui:C0023810 | denotes | lipopolysaccharide |
| E7-ab-1 | 358-365 | cui:C0205263 | denotes | induced |
| E8-ab-1 | 366-379 | cui:C0040649 | denotes | transcription |
| E9-ab-1 | 383-410 | cui:C1448177 | denotes | tumor necrosis factor-alpha |
| E10-ab-1 | 415-432 | cui:C0021753 | denotes | interleukin-1beta |
| E11-ab-1 | 436-441 | cui:C0025914 | denotes | mouse |
| E12-ab-1 | 442-452 | cui:C0024432 | denotes | macrophage |
| E13-ab-1 | 463-468 | cui:C0007634 | denotes | cells |
| T2 | 320-328 | INHIBITS | denotes | inhibits |
| T3 | 320-328 | INHIBITS | denotes | inhibits |
| T4 | 433-435 | LOCATION_OF | denotes | in |
| T5 | 433-435 | LOCATION_OF | denotes | in |
| E1-ab-2 | 478-483 | cui:C0008972 | denotes | study |
| E2-ab-2 | 504-511 | cui:C1280500 | denotes | effects |
| E3-ab-2 | 515-518 | cui:C0041286 | denotes | DZA |
| E4-ab-2 | 522-529 | cui:C0521447 | denotes | nuclear |
| E5-ab-2 | 530-536 | cui:C1521761 | denotes | factor |
| E6-ab-2 | 556-566 | cui:C0851285 | denotes | regulation |
| E1-ab-3 | 568-571 | cui:C0041286 | denotes | DZA |
| E2-ab-3 | 585-600 | cui:C0040649 | denotes | transcriptional |
| E3-ab-3 | 601-609 | cui:C0439167 | denotes | activity |
| E4-ab-3 | 613-622 | cui:C0521447 | denotes | NF-kappaB |
| E5-ab-3 | 613-622 | cui:C1521761 | denotes | NF-kappaB |
| E6-ab-3 | 648-651 | cui:C0599933 | denotes | p65 |
| E7-ab-3 | 653-656 | cui:C0751998 | denotes | Rel |
| E8-ab-3 | 660-675 | cui:C0031715 | denotes | phosphorylation |
| E9-ab-3 | 701-722 | cui:C1518440 | denotes | nuclear translocation |
| E10-ab-3 | 727-738 | cui:C1148673 | denotes | DNA binding |
| E11-ab-3 | 739-747 | cui:C0439167 | denotes | activity |
| T6 | 572-580 | DISRUPTS | denotes | inhibits |
| T7 | 684-693 | DISRUPTS | denotes | reduction |
| E1-ab-4 | 753-763 | cui:C0243077 | denotes | inhibitory |
| E2-ab-4 | 764-770 | cui:C1280500 | denotes | effect |
| E3-ab-4 | 774-777 | cui:C0041286 | denotes | DZA |
| E4-ab-4 | 781-790 | cui:C0521447 | denotes | NF-kappaB |
| E5-ab-4 | 781-790 | cui:C1521761 | denotes | NF-kappaB |
| E6-ab-4 | 791-806 | cui:C0040649 | denotes | transcriptional |
| E7-ab-4 | 807-815 | cui:C0439167 | denotes | activity |
| E8-ab-4 | 838-846 | cui:C0442796 | denotes | addition |
| E9-ab-4 | 850-862 | cui:C0019878 | denotes | homocysteine |
| T8 | 764-770 | AFFECTS | denotes | effect |
| E1-ab-5 | 880-883 | cui:C0041286 | denotes | DZA |
| E2-ab-5 | 897-908 | cui:C0030946 | denotes | proteolytic |
| E3-ab-5 | 909-920 | cui:C0243125 | denotes | degradation |
| E4-ab-5 | 924-936 | cui:C0126732 | denotes | IkappaBalpha |
| E5-ab-5 | 942-945 | cui:C1518422 | denotes | not |
| E6-ab-5 | 946-957 | cui:C0166033 | denotes | IkappaBbeta |
| E7-ab-5 | 975-983 | cui:C0442805 | denotes | increase |
| E8-ab-5 | 987-998 | cui:C1148673 | denotes | DNA binding |
| E9-ab-5 | 999-1007 | cui:C0439167 | denotes | activity |
| E10-ab-5 | 1011-1020 | cui:C0521447 | denotes | NF-kappaB |
| E11-ab-5 | 1011-1020 | cui:C1521761 | denotes | NF-kappaB |
| E12-ab-5 | 1058-1073 | cui:C0040649 | denotes | transcriptional |
| E13-ab-5 | 1074-1082 | cui:C0439167 | denotes | activity |
| E14-ab-5 | 1096-1101 | cui:C0007634 | denotes | cells |
| T9 | 884-892 | STIMULATES | denotes | promotes |
| T10 | 975-983 | AUGMENTS | denotes | increase |
| T11 | 1083-1085 | LOCATION_OF | denotes | in |
| E1-ab-6 | 1120-1132 | cui:C0126732 | denotes | IkappaBalpha |
| E2-ab-6 | 1136-1139 | cui:C0041286 | denotes | DZA |
| E3-ab-6 | 1163-1177 | cui:C0663914 | denotes | IkappaB kinase |
| E4-ab-6 | 1178-1185 | cui:C0439855 | denotes | complex |
| E5-ab-6 | 1218-1226 | cui:C0442796 | denotes | addition |
| E6-ab-6 | 1230-1242 | cui:C0019878 | denotes | homocysteine |
| T12 | 1201-1210 | INTERACTS_WITH | denotes | modulated |
| E1-ab-7 | 1249-1254 | cui:C0008972 | denotes | study |
| E2-ab-7 | 1278-1281 | cui:C0041286 | denotes | DZA |
| E3-ab-7 | 1291-1297 | cui:C0237399 | denotes | potent |
| E4-ab-7 | 1298-1302 | cui:C0013227 | denotes | drug |
| E5-ab-7 | 1311-1320 | cui:C0087111 | denotes | treatment |
| E6-ab-7 | 1324-1332 | cui:C0012634 | denotes | diseases |
| E7-ab-7 | 1342-1351 | cui:C0521447 | denotes | NF-kappaB |
| E8-ab-7 | 1342-1351 | cui:C1521761 | denotes | NF-kappaB |
| E9-ab-7 | 1360-1367 | cui:C0205099 | denotes | central |
| E10-ab-7 | 1368-1378 | cui:C1136169 | denotes | pathogenic |
| E11-ab-7 | 1379-1383 | cui:C0035820 | denotes | role |
| E12-ab-7 | 1405-1409 | cui:C0336791 | denotes | tool |
| E13-ab-7 | 1414-1422 | cui:C0008972 | denotes | studying |
| E14-ab-7 | 1427-1437 | cui:C0851285 | denotes | regulation |
| E15-ab-7 | 1442-1465 | cui:C1254359 | denotes | physiological functions |
| E16-ab-7 | 1469-1478 | cui:C0521447 | denotes | NF-kappaB |
| E17-ab-7 | 1469-1478 | cui:C1521761 | denotes | NF-kappaB |
| T13 | 1278-1302 | ISA | denotes | DZA may be a potent drug |
| T14 | 1311-1320 | TREATS | denotes | treatment |
| T15 | 1379-1383 | ASSOCIATED_WITH | denotes | role |
| T16 | 1278-1302 | TREATS | denotes | DZA may be a potent drug |
| R1 | E6-ti-2 | T1 | subjectOf | IkappaBalpha,Inhibition |
| R2 | E3-ti-2 | T1 | objectOf | transcriptional,Inhibition |
| R3 | E4-ab-1 | T2 | subjectOf | S-adenosylhomocysteine hydrolase,inhibits |
| R4 | E9-ab-1 | T2 | objectOf | tumor necrosis factor-alpha,inhibits |
| R5 | E4-ab-1 | T3 | subjectOf | S-adenosylhomocysteine hydrolase,inhibits |
| R6 | E10-ab-1 | T3 | objectOf | interleukin-1beta,inhibits |
| R7 | E13-ab-1 | T4 | subjectOf | cells,in |
| R8 | E10-ab-1 | T4 | objectOf | interleukin-1beta,in |
| R9 | E13-ab-1 | T5 | subjectOf | cells,in |
| R10 | E9-ab-1 | T5 | objectOf | tumor necrosis factor-alpha,in |
| R11 | E1-ab-3 | T6 | subjectOf | DZA,inhibits |
| R12 | E2-ab-3 | T6 | objectOf | transcriptional,inhibits |
| R13 | E7-ab-3 | T7 | subjectOf | Rel,reduction |
| R14 | E9-ab-3 | T7 | objectOf | nuclear translocation,reduction |
| R15 | E3-ab-4 | T8 | subjectOf | DZA,effect |
| R16 | E6-ab-4 | T8 | objectOf | transcriptional,effect |
| R17 | E1-ab-5 | T9 | subjectOf | DZA,promotes |
| R18 | E2-ab-5 | T9 | objectOf | proteolytic,promotes |
| R19 | E6-ab-5 | T10 | subjectOf | IkappaBbeta,increase |
| R20 | E8-ab-5 | T10 | objectOf | DNA binding,increase |
| R21 | E14-ab-5 | T11 | subjectOf | cells,in |
| R22 | E4-ab-5 | T11 | objectOf | IkappaBalpha,in |
| R23 | E2-ab-6 | T12 | subjectOf | DZA,modulated |
| R24 | E6-ab-6 | T12 | objectOf | homocysteine,modulated |
| R25 | E2-ab-7 | T13 | subjectOf | DZA,DZA may be a potent drug |
| R26 | E4-ab-7 | T13 | objectOf | drug,DZA may be a potent drug |
| R27 | E4-ab-7 | T14 | subjectOf | drug,treatment |
| R28 | E6-ab-7 | T14 | objectOf | diseases,treatment |
| R29 | E10-ab-7 | T15 | subjectOf | pathogenic,role |
| R30 | E6-ab-7 | T15 | objectOf | diseases,role |
| R31 | E2-ab-7 | T16 | subjectOf | DZA,DZA may be a potent drug |
| R32 | E6-ab-7 | T16 | objectOf | diseases,DZA may be a potent drug |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-105 | Sentence | denotes | 3-deazaadenosine, a S-adenosylhomocysteine hydrolase inhibitor, has dual effects on NF-kappaB regulation. |
| S2 | 106-197 | Sentence | denotes | Inhibition of NF-kappaB transcriptional activity and promotion of IkappaBalpha degradation. |
| S3 | 198-469 | Sentence | denotes | Previously we reported that 3-deazaadenosine (DZA), a potent inhibitor and substrate for S-adenosylhomocysteine hydrolase inhibits bacterial lipopolysaccharide-induced transcription of tumor necrosis factor-alpha and interleukin-1beta in mouse macrophage RAW 264.7 cells. |
| S4 | 470-567 | Sentence | denotes | In this study, we demonstrate the effects of DZA on nuclear factor-kappaB (NF-kappaB) regulation. |
| S5 | 568-748 | Sentence | denotes | DZA inhibits the transcriptional activity of NF-kappaB through the hindrance of p65 (Rel-A) phosphorylation without reduction of its nuclear translocation and DNA binding activity. |
| S6 | 749-863 | Sentence | denotes | The inhibitory effect of DZA on NF-kappaB transcriptional activity is potentiated by the addition of homocysteine. |
| S7 | 864-1102 | Sentence | denotes | Taken together, DZA promotes the proteolytic degradation of IkappaBalpha, but not IkappaBbeta, resulting in an increase of DNA binding activity of NF-kappaB in the nucleus in the absence of its transcriptional activity in RAW 264.7 cells. |
| S8 | 1103-1243 | Sentence | denotes | The reduction of IkappaBalpha by DZA is neither involved in IkappaB kinase complex activation nor modulated by the addition of homocysteine. |
| S9 | 1244-1479 | Sentence | denotes | This study strongly suggests that DZA may be a potent drug for the treatment of diseases in which NF-kappaB plays a central pathogenic role, as well as a useful tool for studying the regulation and physiological functions of NF-kappaB. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-16 | other_organic_compound | denotes | 3-deazaadenosine |
| T2 | 20-52 | protein_molecule | denotes | S-adenosylhomocysteine hydrolase |
| T3 | 84-93 | protein_complex | denotes | NF-kappaB |
| T4 | 120-129 | protein_complex | denotes | NF-kappaB |
| T5 | 172-184 | protein_molecule | denotes | IkappaBalpha |
| T6 | 226-242 | other_organic_compound | denotes | 3-deazaadenosine |
| T7 | 287-319 | protein_molecule | denotes | S-adenosylhomocysteine hydrolase |
| T8 | 339-379 | other_name | denotes | lipopolysaccharide-induced transcription |
| T9 | 383-410 | protein_molecule | denotes | tumor necrosis factor-alpha |
| T10 | 415-432 | protein_molecule | denotes | interleukin-1beta |
| T11 | 436-468 | cell_line | denotes | mouse macrophage RAW 264.7 cells |
| T12 | 515-518 | other_organic_compound | denotes | DZA |
| T13 | 522-543 | protein_complex | denotes | nuclear factor-kappaB |
| T14 | 545-554 | protein_complex | denotes | NF-kappaB |
| T15 | 568-571 | other_organic_compound | denotes | DZA |
| T16 | 613-622 | protein_complex | denotes | NF-kappaB |
| T17 | 648-651 | protein_complex | denotes | p65 |
| T18 | 653-658 | protein_complex | denotes | Rel-A |
| T19 | 727-747 | other_name | denotes | DNA binding activity |
| T20 | 774-777 | other_organic_compound | denotes | DZA |
| T21 | 781-790 | protein_complex | denotes | NF-kappaB |
| T22 | 850-862 | amino_acid_monomer | denotes | homocysteine |
| T23 | 880-883 | other_organic_compound | denotes | DZA |
| T24 | 924-936 | protein_molecule | denotes | IkappaBalpha |
| T25 | 946-957 | protein_molecule | denotes | IkappaBbeta |
| T26 | 987-1007 | other_name | denotes | DNA binding activity |
| T27 | 1011-1020 | protein_complex | denotes | NF-kappaB |
| T28 | 1028-1035 | cell_component | denotes | nucleus |
| T29 | 1058-1082 | other_name | denotes | transcriptional activity |
| T30 | 1086-1101 | cell_line | denotes | RAW 264.7 cells |
| T31 | 1120-1132 | protein_molecule | denotes | IkappaBalpha |
| T32 | 1136-1139 | other_organic_compound | denotes | DZA |
| T33 | 1163-1185 | protein_complex | denotes | IkappaB kinase complex |
| T34 | 1230-1242 | amino_acid_monomer | denotes | homocysteine |
| T35 | 1278-1281 | other_organic_compound | denotes | DZA |
| T36 | 1342-1351 | protein_complex | denotes | NF-kappaB |
| T37 | 1442-1465 | other_name | denotes | physiological functions |
| T38 | 1469-1478 | protein_complex | denotes | NF-kappaB |
metamap-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 227-243 | C0047329 | denotes | -deazaadenosine |
| T2 | 1-17 | C0047329 | denotes | -deazaadenosine, |
| T3 | 1012-1021 | C0079904 | denotes | F-kappaB |
| T4 | 782-791 | C0079904 | denotes | F-kappaB |
| T5 | 614-623 | C0079904 | denotes | F-kappaB |
| T6 | 523-544 | C0079904 | denotes | uclear factor-kappaB |
| T7 | 85-94 | C0079904 | denotes | F-kappaB |
| T8 | 1121-1133 | C0126732 | denotes | kappaBalpha |
| T9 | 925-937 | C0126732 | denotes | kappaBalpha, |
| T10 | 173-185 | C0126732 | denotes | kappaBalpha |
| T11 | 910-921 | C0699900 | denotes | egradation |
| T12 | 186-197 | C0699900 | denotes | egradation. |
| T13 | 885-893 | C0033414 | denotes | romotes |
| T14 | 160-169 | C0033414 | denotes | romotion |
| T15 | 44-63 | C1657294 | denotes | ydrolase inhibitor, |
| T16 | 107-155 | C2248542 | denotes | nhibition of NF-kappaB transcriptional activity |
| T17 | 1428-1438 | C1327622 | denotes | egulation |
| T18 | 557-567 | C1327622 | denotes | egulation. |
| T19 | 95-105 | C1327622 | denotes | egulation. |
| T20 | 765-771 | C1280500 | denotes | ffect |
| T21 | 505-512 | C1280500 | denotes | ffects |
| T22 | 74-81 | C1280500 | denotes | ffects |
| T23 | 69-73 | C1554184 | denotes | ual |
| T24 | 121-130 | C0521447 | denotes | F-kappaB |
| T25 | 1279-1282 | C0041286 | denotes | ZA |
| T26 | 1137-1140 | C0041286 | denotes | ZA |
| T27 | 881-883 | C0041286 | denotes | ZA |
| T28 | 775-778 | C0041286 | denotes | ZA |
| T29 | 569-572 | C0041286 | denotes | ZA |
| T30 | 516-519 | C0041286 | denotes | ZA |
| T31 | 1059-1074 | C0040649 | denotes | ranscriptional |
| T32 | 792-806 | C0040649 | denotes | ranscriptional |
| T33 | 586-601 | C0040649 | denotes | ranscriptional |
| T34 | 367-380 | C0040649 | denotes | ranscription |
| T35 | 1087-1090 | C0001884 | denotes | AW |
| T36 | 454-457 | C0001884 | denotes | AW |
| T37 | 1231-1243 | C0019878 | denotes | omocysteine. |
| T38 | 851-863 | C0019878 | denotes | omocysteine. |
| T39 | 1029-1036 | C0007610 | denotes | ucleus |
| T40 | 1312-1321 | C0039798 | denotes | reatment |
| T41 | 573-581 | C0018790 | denotes | nhibits |
| T42 | 321-329 | C0018790 | denotes | nhibits |
| T43 | 988-991 | C0012854 | denotes | NA |
| T44 | 728-731 | C0012854 | denotes | NA |
| T45 | 384-411 | C1456820 | denotes | umor necrosis factor-alpha |
| T46 | 808-816 | C1561536 | denotes | ctivity |
| T47 | 340-358 | C0023810 | denotes | ipopolysaccharide- |
| T48 | 947-958 | C0166033 | denotes | kappaBbeta, |
| T49 | 661-676 | C0031715 | denotes | hosphorylation |
| T50 | 754-764 | C3463820 | denotes | nhibitory |
| T51 | 443-453 | C0024432 | denotes | acrophage |
| T52 | 1250-1255 | C2603343 | denotes | tudy |
| T53 | 1415-1423 | C2603343 | denotes | tudying |
| T54 | 479-484 | C2603343 | denotes | tudy, |
| T55 | 1325-1333 | C0012634 | denotes | iseases |
| T56 | 992-1008 | C2266866 | denotes | inding activity |
| T57 | 732-748 | C2266866 | denotes | inding activity. |
| T58 | 1219-1227 | C1883712 | denotes | ddition |
| T59 | 839-847 | C1883712 | denotes | ddition |
| T60 | 988-999 | C1148673 | denotes | NA binding |
| T61 | 728-739 | C1148673 | denotes | NA binding |
| T62 | 1097-1102 | C0007634 | denotes | ells. |
| T63 | 464-469 | C0007634 | denotes | ells. |
| T64 | 1108-1117 | C0441610 | denotes | eduction |
| T65 | 685-694 | C0441610 | denotes | eduction |
| T66 | 1087-1090 | C1709843 | denotes | AW |
| T67 | 454-457 | C1709843 | denotes | AW |
| T68 | 1044-1051 | C0332197 | denotes | bsence |
| T69 | 290-320 | C1829645 | denotes | denosylhomocysteine hydrolase |
| T70 | 1353-1358 | C0600138 | denotes | lays |
| T71 | 213-221 | C0684224 | denotes | eported |
| T72 | 649-652 | C3540646 | denotes | 65 |
| T73 | 865-870 | C1883727 | denotes | aken |
| T74 | 871-879 | C1883357 | denotes | ogether, |
| T75 | 1265-1273 | C1705535 | denotes | uggests |
| T76 | 260-269 | C1999216 | denotes | nhibitor |
| T77 | 1164-1186 | C1166825 | denotes | kappaB kinase complex |
| T78 | 274-283 | C1710236 | denotes | ubstrate |
| T79 | 1380-1384 | C1705810 | denotes | ole, |
| T80 | 1399-1410 | C0871532 | denotes | seful tool |
| T81 | 1406-1410 | C2827396 | denotes | ool |
| T82 | 1187-1197 | C1879547 | denotes | ctivation |
| T83 | 1457-1466 | C0542341 | denotes | unctions |
| T84 | 1152-1160 | C1314939 | denotes | nvolved |
| T85 | 1202-1211 | C0443264 | denotes | odulated |
| T86 | 960-972 | C0332294 | denotes | esulting in |
| T87 | 976-984 | C0442805 | denotes | ncrease |
| T88 | 1292-1303 | C0678792 | denotes | otent drug |
| T89 | 943-946 | C1518422 | denotes | ot |
| T90 | 1361-1368 | C1879652 | denotes | entral |
| T91 | 1369-1379 | C0450254 | denotes | athogenic |
| T92 | 702-723 | C1518440 | denotes | uclear translocation |
| T93 | 253-259 | C3245505 | denotes | otent |
| T94 | 898-909 | C1947941 | denotes | roteolytic |
| T95 | 1443-1456 | C0205463 | denotes | hysiological |
| T96 | 330-338 | C0521009 | denotes | acterial |
| T97 | 359-366 | C0205263 | denotes | nduced |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 383-388 | HP_0002664 | denotes | tumor |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 383-388 | Phenotype | denotes | tumor | HP:0002664 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 383-388 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 436-441 | OrganismTaxon | denotes | mouse | 10088|10090 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 442-452 | Body_part | denotes | macrophage | http://purl.obolibrary.org/obo/CL_0000235 |
| T2 | 1028-1035 | Body_part | denotes | nucleus | http://purl.obolibrary.org/obo/GO_0005634|http://purl.obolibrary.org/obo/UBERON_0000125 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 442-452 | Cell | denotes | macrophage | http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394 |