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PubMed:10367897 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-8 protein denotes CBP/p300
T2 20-23 protein denotes Raf
T3 24-27 protein denotes Rac
T4 83-89 protein denotes NF-ATc
T5 116-122 protein denotes NF-ATc
T6 147-167 protein denotes transcription factor
T7 197-210 cell_type denotes T lymphocytes
T8 215-229 cell_type denotes cardiomyocytes
T9 253-282 protein denotes transcriptional co-activators
T10 283-291 protein denotes CBP/p300
T11 332-375 protein denotes inducible N-terminal transactivation domain
T12 379-385 protein denotes NF-ATc
T13 387-392 protein denotes TAD-A
T14 409-442 protein denotes N terminal transactivation domain
T15 446-451 protein denotes c-Jun
T16 453-458 protein denotes TAD-A
T17 553-561 protein denotes CBP/p300
T18 595-600 protein denotes c-Raf
T19 605-608 protein denotes Rac
T20 637-645 protein denotes CBP/p300
T21 667-672 protein denotes TAD-A
T22 713-721 protein denotes CBP/p300
T23 797-800 protein denotes CBP
T24 848-861 protein denotes wild-type CBP
T25 865-872 cell_type denotes T cells
T26 887-895 protein denotes CBP/p300
T27 949-954 protein denotes NF-AT
T28 982-989 cell_type denotes T cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-115 Sentence denotes CBP/p300 integrates Raf/Rac-signaling pathways in the transcriptional induction of NF-ATc during T cell activation.
S2 116-230 Sentence denotes NF-ATc, an inducibly expressed transcription factor, controls gene expression in T lymphocytes and cardiomyocytes.
S3 231-393 Sentence denotes We show here that the transcriptional co-activators CBP/p300 bind to and control the activity of the inducible N-terminal transactivation domain of NF-ATc, TAD-A.
S4 394-562 Sentence denotes Similar to the N terminal transactivation domain of c-Jun, TAD-A is inducibly phosphorylated, but this phosphorylation is dispensable for the interaction with CBP/p300.
S5 563-776 Sentence denotes Constitutive active versions of c-Raf and Rac synergistically enhance the CBP/p300-mediated increase of TAD-A activity, indicating the important role CBP/p300 plays in the integration of T cell activation signals.
S6 777-990 Sentence denotes Since a mutation of CBP abolishing HAT activity is almost as active as wild-type CBP in T cells, functions of CBP/p300 other than histone acetylation appear to control the NF-AT-dependent transcription in T cells.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-8 NP denotes CBP/p300
C2 83-89 NP denotes NF-ATc
C3 116-122 NP denotes NF-ATc
C4 124-167 NP denotes an inducibly expressed transcription factor
C5 197-210 NP denotes T lymphocytes
C6 249-291 NP denotes the transcriptional co-activators CBP/p300
C8 379-385 NP denotes NF-ATc
C7 328-385 NP denotes the inducible N-terminal transactivation domain of NF-ATc
C9 387-392 NP denotes TAD-A
C10 453-458 NP denotes TAD-A
C11 553-561 NP denotes CBP/p300
C12 713-721 NP denotes CBP/p300
C13 865-872 NP denotes T cells
C14 887-895 NP denotes CBP/p300
C15 982-989 NP denotes T cells
R1 C3 C2 coref-ident NF-ATc,NF-ATc
R2 C4 C3 coref-appos an inducibly expressed transcription factor,NF-ATc
R3 C6 C1 coref-ident the transcriptional co-activators CBP/p300,CBP/p300
R4 C8 C3 coref-ident NF-ATc,NF-ATc
R5 C9 C7 coref-appos TAD-A,the inducible N-terminal transactivation domain of NF-ATc
R6 C10 C7 coref-ident TAD-A,the inducible N-terminal transactivation domain of NF-ATc
R7 C11 C6 coref-ident CBP/p300,the transcriptional co-activators CBP/p300
R8 C12 C11 coref-ident CBP/p300,CBP/p300
R9 C13 C5 coref-ident T cells,T lymphocytes
R10 C14 C12 coref-ident CBP/p300,CBP/p300
R11 C15 C13 coref-ident T cells,T cells

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-8 protein_molecule denotes CBP/p300
T2 20-23 protein_molecule denotes Raf
T3 24-27 protein_molecule denotes Rac
T4 83-89 protein_molecule denotes NF-ATc
T5 97-114 other_name denotes T cell activation
T6 116-122 protein_molecule denotes NF-ATc
T7 147-167 protein_family_or_group denotes transcription factor
T8 178-193 other_name denotes gene expression
T9 197-210 cell_type denotes T lymphocytes
T10 215-229 cell_type denotes cardiomyocytes
T11 253-282 protein_family_or_group denotes transcriptional co-activators
T12 283-291 protein_molecule denotes CBP/p300
T13 332-375 protein_domain_or_region denotes inducible N-terminal transactivation domain
T14 379-385 protein_molecule denotes NF-ATc
T15 387-392 protein_molecule denotes TAD-A
T16 409-442 protein_domain_or_region denotes N terminal transactivation domain
T17 446-451 protein_molecule denotes c-Jun
T18 453-458 protein_molecule denotes TAD-A
T19 553-561 protein_molecule denotes CBP/p300
T20 595-600 protein_molecule denotes c-Raf
T21 605-608 protein_molecule denotes Rac
T22 637-645 protein_molecule denotes CBP/p300
T23 667-672 protein_molecule denotes TAD-A
T24 713-721 protein_molecule denotes CBP/p300
T25 750-767 other_name denotes T cell activation
T26 797-800 protein_molecule denotes CBP
T27 848-861 protein_molecule denotes wild-type CBP
T28 865-872 cell_type denotes T cells
T29 887-895 protein_molecule denotes CBP/p300
T30 949-954 protein_molecule denotes NF-AT
T31 982-989 cell_type denotes T cells