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CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 6-26 Cell denotes alveolar macrophages http://purl.obolibrary.org/obo/CL:0000583
T2 123-143 Cell denotes alveolar macrophages http://purl.obolibrary.org/obo/CL:0000583
T3 176-190 Cell denotes precursor cell http://purl.obolibrary.org/obo/CL:0011115
T4 202-210 Cell denotes monocyte http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T6 212-220 Cell denotes monocyte http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T8 324-344 Cell denotes alveolar macrophages http://purl.obolibrary.org/obo/CL:0000583
T9 528-548 Cell denotes alveolar macrophages http://purl.obolibrary.org/obo/CL:0000583
T10 892-912 Cell denotes alveolar macrophages http://purl.obolibrary.org/obo/CL:0000583
T11 927-936 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T13 979-988 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T15 994-1004 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T17 1097-1106 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T19 1110-1129 Cell denotes alveolar macrophage http://purl.obolibrary.org/obo/CL:0000583
T20 1119-1129 Cell denotes macrophage http://purl.obolibrary.org/obo/CL:0000235|http://purl.obolibrary.org/obo/CL:0000394
T22 1268-1277 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T24 1283-1303 Cell denotes alveolar macrophages http://purl.obolibrary.org/obo/CL:0000583
T25 1445-1465 Cell denotes alveolar macrophages http://purl.obolibrary.org/obo/CL:0000583
T26 1480-1489 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054

sentences

Id Subject Object Predicate Lexical cue
T1 0-89 Sentence denotes Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity.
T2 90-291 Sentence denotes Although many functions of human alveolar macrophages are altered compared with their precursor cell, the blood monocyte (monocyte), the reason(s) for these functional changes have not been determined.
T3 292-397 Sentence denotes We recently reported that human alveolar macrophages do not express AP-1 DNA binding activity (Monick, M.
T4 398-412 Sentence denotes M., Carter, A.
T5 413-443 Sentence denotes B., Gudmundsson, G., Geist, L.
T6 444-467 Sentence denotes J., and Hunninghake, G.
T7 468-481 Sentence denotes W. (1998) Am.
T8 482-484 Sentence denotes J.
T9 485-493 Sentence denotes Physiol.
T10 494-510 Sentence denotes 275, L389-L397).
T11 511-709 Sentence denotes To determine why alveolar macrophages do not express AP-1 DNA binding activity, we first showed that there was not a decrease in expression of the FOS and JUN proteins that make up the AP-1 complex.
T12 710-937 Sentence denotes There was, however, a significant difference in the amounts of the nuclear protein, REF-1 (which regulates AP-1 DNA binding by altering the redox status of FOS and JUN proteins), in alveolar macrophages compared with monocytes.
T13 938-1054 Sentence denotes In addition, in vitro differentiation of monocytes to a macrophage-like cell resulted in decreased amounts of REF-1.
T14 1055-1197 Sentence denotes Finally, addition of REF-1 from activated monocytes to alveolar macrophage nuclear proteins resulted in a marked increase in AP-1 DNA binding.
T15 1198-1357 Sentence denotes These studies strongly suggest that the process of differentiation of monocytes into alveolar macrophages is associated with a loss of REF-1 and AP-1 activity.
T16 1358-1490 Sentence denotes This observation may explain, in part, some of the functional differences observed for alveolar macrophages compared with monocytes.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 196-201 http://purl.obolibrary.org/obo/MAT_0000083 denotes blood
T2 196-201 http://purl.obolibrary.org/obo/MAT_0000315 denotes blood

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-26 cell_type denotes Human alveolar macrophages
T2 53-58 protein denotes REF-1
T3 63-67 protein denotes AP-1
T4 117-143 cell_type denotes human alveolar macrophages
T5 176-190 cell_type denotes precursor cell
T6 196-210 cell_type denotes blood monocyte
T7 212-220 cell_type denotes monocyte
T8 318-344 cell_type denotes human alveolar macrophages
T9 360-364 protein denotes AP-1
T10 528-548 cell_type denotes alveolar macrophages
T11 564-568 protein denotes AP-1
T12 658-678 protein denotes FOS and JUN proteins
T13 696-700 protein denotes AP-1
T14 777-792 protein denotes nuclear protein
T15 794-799 protein denotes REF-1
T16 817-821 protein denotes AP-1
T17 866-869 protein denotes FOS
T18 874-886 protein denotes JUN proteins
T19 892-912 cell_type denotes alveolar macrophages
T20 927-936 cell_type denotes monocytes
T21 979-988 cell_type denotes monocytes
T22 994-1014 cell_type denotes macrophage-like cell
T23 1048-1053 protein denotes REF-1
T24 1076-1081 protein denotes REF-1
T25 1087-1106 cell_type denotes activated monocytes
T26 1180-1184 protein denotes AP-1
T27 1268-1277 cell_type denotes monocytes
T28 1283-1303 cell_type denotes alveolar macrophages
T29 1333-1338 protein denotes REF-1
T30 1343-1347 protein denotes AP-1
T31 1445-1465 cell_type denotes alveolar macrophages
T32 1480-1489 cell_type denotes monocytes

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-89 Sentence denotes Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity.
S2 90-291 Sentence denotes Although many functions of human alveolar macrophages are altered compared with their precursor cell, the blood monocyte (monocyte), the reason(s) for these functional changes have not been determined.
S3 292-510 Sentence denotes We recently reported that human alveolar macrophages do not express AP-1 DNA binding activity (Monick, M. M., Carter, A. B., Gudmundsson, G., Geist, L. J., and Hunninghake, G. W. (1998) Am. J. Physiol. 275, L389-L397).
S4 511-709 Sentence denotes To determine why alveolar macrophages do not express AP-1 DNA binding activity, we first showed that there was not a decrease in expression of the FOS and JUN proteins that make up the AP-1 complex.
S5 710-937 Sentence denotes There was, however, a significant difference in the amounts of the nuclear protein, REF-1 (which regulates AP-1 DNA binding by altering the redox status of FOS and JUN proteins), in alveolar macrophages compared with monocytes.
S6 938-1054 Sentence denotes In addition, in vitro differentiation of monocytes to a macrophage-like cell resulted in decreased amounts of REF-1.
S7 1055-1197 Sentence denotes Finally, addition of REF-1 from activated monocytes to alveolar macrophage nuclear proteins resulted in a marked increase in AP-1 DNA binding.
S8 1198-1357 Sentence denotes These studies strongly suggest that the process of differentiation of monocytes into alveolar macrophages is associated with a loss of REF-1 and AP-1 activity.
S9 1358-1490 Sentence denotes This observation may explain, in part, some of the functional differences observed for alveolar macrophages compared with monocytes.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-26 NP denotes Human alveolar macrophages
C2 53-88 NP denotes REF-1 and AP-1 DNA binding activity
C3 117-143 NP denotes human alveolar macrophages
C5 170-175 NP denotes their
C4 170-190 NP denotes their precursor cell
C6 192-221 NP denotes the blood monocyte (monocyte)
C7 318-344 NP denotes human alveolar macrophages
C8 360-385 NP denotes AP-1 DNA binding activity
C9 528-548 NP denotes alveolar macrophages
C10 564-589 NP denotes AP-1 DNA binding activity
C11 654-678 NP denotes the FOS and JUN proteins
C12 679-683 NP denotes that
C13 773-792 NP denotes the nuclear protein
C14 794-887 NP denotes REF-1 (which regulates AP-1 DNA binding by altering the redox status of FOS and JUN proteins)
C15 892-912 NP denotes alveolar macrophages
C16 927-936 NP denotes monocytes
C17 979-988 NP denotes monocytes
C18 1048-1053 NP denotes REF-1
C19 1076-1081 NP denotes REF-1
C20 1268-1277 NP denotes monocytes
C21 1283-1303 NP denotes alveolar macrophages
C22 1333-1356 NP denotes REF-1 and AP-1 activity
C23 1445-1465 NP denotes alveolar macrophages
C24 1480-1489 NP denotes monocytes
R1 C3 C1 coref-ident human alveolar macrophages,Human alveolar macrophages
R2 C5 C3 coref-pron their,human alveolar macrophages
R3 C6 C4 coref-appos the blood monocyte (monocyte),their precursor cell
R4 C7 C3 coref-ident human alveolar macrophages,human alveolar macrophages
R5 C9 C7 coref-ident alveolar macrophages,human alveolar macrophages
R6 C10 C8 coref-ident AP-1 DNA binding activity,AP-1 DNA binding activity
R7 C12 C11 coref-relat that,the FOS and JUN proteins
R8 C14 C13 coref-appos REF-1 (which regulates AP-1 DNA binding by altering the redox status of FOS and JUN proteins),the nuclear protein
R9 C15 C9 coref-ident alveolar macrophages,alveolar macrophages
R10 C16 C4 coref-ident monocytes,their precursor cell
R11 C17 C16 coref-ident monocytes,monocytes
R12 C18 C13 coref-ident REF-1,the nuclear protein
R13 C19 C18 coref-ident REF-1,REF-1
R14 C20 C17 coref-ident monocytes,monocytes
R15 C21 C15 coref-ident alveolar macrophages,alveolar macrophages
R16 C22 C2 coref-ident REF-1 and AP-1 activity,REF-1 and AP-1 DNA binding activity
R17 C23 C21 coref-ident alveolar macrophages,alveolar macrophages
R18 C24 C20 coref-ident monocytes,monocytes

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-26 cell_type denotes Human alveolar macrophages
T2 53-58 protein_molecule denotes REF-1
T3 63-67 protein_molecule denotes AP-1
T4 117-143 cell_type denotes human alveolar macrophages
T5 176-190 cell_type denotes precursor cell
T6 196-210 cell_type denotes blood monocyte
T7 212-220 cell_type denotes monocyte
T8 318-344 cell_type denotes human alveolar macrophages
T9 360-364 protein_molecule denotes AP-1
T10 528-548 cell_type denotes alveolar macrophages
T11 564-568 protein_molecule denotes AP-1
T12 696-700 protein_molecule denotes AP-1
T13 777-792 protein_family_or_group denotes nuclear protein
T14 794-799 protein_molecule denotes REF-1
T15 817-821 protein_molecule denotes AP-1
T16 866-869 protein_family_or_group denotes FOS
T17 874-886 protein_family_or_group denotes JUN proteins
T18 892-912 cell_type denotes alveolar macrophages
T19 927-936 cell_type denotes monocytes
T20 979-988 cell_type denotes monocytes
T21 994-1014 cell_type denotes macrophage-like cell
T22 1048-1053 protein_molecule denotes REF-1
T23 1076-1081 protein_molecule denotes REF-1
T24 1087-1106 cell_type denotes activated monocytes
T25 1180-1184 protein_molecule denotes AP-1
T26 1268-1277 cell_type denotes monocytes
T27 1283-1303 cell_type denotes alveolar macrophages
T28 1333-1338 protein_molecule denotes REF-1
T29 1343-1347 protein_molecule denotes AP-1
T30 1445-1465 cell_type denotes alveolar macrophages
T31 1480-1489 cell_type denotes monocytes

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 196-201 Body_part denotes blood http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 0-5 OrganismTaxon denotes Human 9606
T2 117-122 OrganismTaxon denotes human 9606
T3 318-323 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 15-26 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T2 132-143 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T3 176-190 Body_part denotes precursor cell http://purl.obolibrary.org/obo/CL_0011115
T4 196-201 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T5 202-210 Body_part denotes monocyte http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T7 212-220 Body_part denotes monocyte http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T9 333-344 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T10 537-548 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T11 901-912 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T12 927-936 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T14 979-988 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T16 994-1004 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T17 1097-1106 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T19 1119-1129 Body_part denotes macrophage http://purl.obolibrary.org/obo/CL_0000235
T20 1268-1277 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T22 1292-1303 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T23 1454-1465 Body_part denotes macrophages http://purl.obolibrary.org/obo/CL_0000235
T24 1480-1489 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054