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PubMed:10362838 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 87-90 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T2 87-90 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T3 141-144 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T4 141-144 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T5 500-503 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T6 500-503 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T7 542-545 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T8 542-545 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T9 700-703 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T10 700-703 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T11 786-789 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T12 786-789 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T13 813-816 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T14 813-816 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T15 859-862 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T16 859-862 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T17 1202-1205 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T18 1202-1205 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T19 1352-1355 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T20 1352-1355 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T21 1425-1428 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T22 1425-1428 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T23 1525-1528 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T24 1525-1528 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T25 1739-1742 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T26 1739-1742 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 87-90 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T3 141-144 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T5 500-503 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T7 542-545 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T9 700-703 Glycan_Motif denotes GM3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G91237TK|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G56516VH
T11 786-789 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T13 813-816 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T15 859-862 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T17 1202-1205 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T19 1352-1355 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T21 1425-1428 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T23 1525-1528 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC
T25 1739-1742 Glycan_Motif denotes GM2 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G79389NT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G61168WC

PMID_GLOBAL

Id Subject Object Predicate Lexical cue
T1 0-162 Sentence denotes Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA.
T2 163-355 Sentence denotes Brefeldin A reversibly disassembles the Golgi complex, causing mixing of the Golgi cisternae with the ER while the trans Golgi network persists as part of a separate endosomal membrane system.
T3 356-513 Sentence denotes Because of this compartmental separation, Brefeldin A treatment has been used to map the sub-Golgi locations of several Golgi enzymes including GM2 synthase.
T4 514-750 Sentence denotes We previously proposed that GM2 synthase might be located in a distal portion of the Golgi complex which in the presence of Brefeldin A would be separated from the substrate ganglioside GM3 present in the mixed ER-Golgi membrane system.
T5 751-976 Sentence denotes In the present study we show using GM2 synthase chimeras that GM2 synthesis was blocked by Brefeldin A when GM2 synthase was distributed throughout all Golgi subcompartments or even when it was restricted to the medial Golgi.
T6 977-1164 Sentence denotes Because these findings opposed our speculation regarding a distal location of this enzyme, we sought an alternative explanation for the inhibition of ganglioside synthesis by Brefeldin A.
T7 1165-1279 Sentence denotes However, Brefeldin A did not degrade GM2 synthase, prevent its homodimerization, or inhibit its in vitro activity.
T8 1280-1444 Sentence denotes Brefeldin A did result in the conversion of a portion of membrane bound GM2 synthase into a soluble form which has minimal capability to produce GM2 in whole cells.
T9 1445-1587 Sentence denotes However, this conversion was not sufficient to explain the nearly total loss of GM2 production in intact cells in the presence of Brefeldin A.
T10 1588-1752 Sentence denotes Nevertheless, the results of this study indicate that Brefeldin A-induced inhibition of ganglioside synthesis cannot be used to deduce the location of GM2 synthase.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 87-90 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T2 87-90 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T3 141-144 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T4 141-144 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T5 500-503 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T6 500-503 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T7 542-545 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T8 542-545 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T9 700-703 https://glytoucan.org/Structures/Glycans/G56516VH denotes GM3
T10 700-703 https://glytoucan.org/Structures/Glycans/G91237TK denotes GM3
T11 786-789 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T12 786-789 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T13 813-816 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T14 813-816 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T15 859-862 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T16 859-862 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T17 1202-1205 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T18 1202-1205 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T19 1352-1355 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T20 1352-1355 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T21 1425-1428 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T22 1425-1428 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T23 1525-1528 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T24 1525-1528 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2
T25 1739-1742 https://glytoucan.org/Structures/Glycans/G61168WC denotes GM2
T26 1739-1742 https://glytoucan.org/Structures/Glycans/G79389NT denotes GM2

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 963-969 http://purl.obolibrary.org/obo/MAT_0000490 denotes medial

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 48-59 FMAID:196811 denotes ganglioside
_T2 48-59 FMAID:82816 denotes ganglioside
_T3 203-216 FMAID:162310 denotes Golgi complex
_T4 203-216 FMAID:63843 denotes Golgi complex
_T5 226-255 FMAID:165057 denotes mixing of the Golgi cisternae
_T6 240-255 FMAID:61750 denotes Golgi cisternae
_T7 240-255 FMAID:165047 denotes Golgi cisternae
_T8 240-255 FMAID:165247 denotes Golgi cisternae
_T9 246-255 FMAID:177796 denotes cisternae
_T10 278-297 FMAID:61756 denotes trans Golgi network
_T11 278-297 FMAID:165153 denotes trans Golgi network
_T12 278-297 FMAID:165054 denotes trans Golgi network
_T13 284-297 FMAID:67108 denotes Golgi network
_T14 284-297 FMAID:165053 denotes Golgi network
_T15 284-297 FMAID:165051 denotes Golgi network
_T16 284-297 FMAID:67113 denotes Golgi network
_T17 290-297 FMAID:179365 denotes network
_T18 329-338 FMAID:67180 denotes endosomal
_T19 329-338 FMAID:165070 denotes endosomal
_T20 437-440 FMAID:90078 denotes map
_T21 577-583 FMAID:171166 denotes distal
_T22 577-583 FMAID:30327 denotes distal
_T23 577-594 FMAID:104897 denotes distal portion of
_T24 599-612 FMAID:63843 denotes Golgi complex
_T25 599-612 FMAID:162310 denotes Golgi complex
_T26 688-699 FMAID:196811 denotes ganglioside
_T27 688-699 FMAID:82816 denotes ganglioside
_T28 728-742 FMAID:199154 denotes Golgi membrane
_T29 963-969 FMAID:49444 denotes medial
_T30 963-969 FMAID:171165 denotes medial
_T31 1036-1042 FMAID:171166 denotes distal
_T32 1036-1042 FMAID:30327 denotes distal
_T33 1127-1138 FMAID:82816 denotes ganglioside
_T34 1127-1138 FMAID:196811 denotes ganglioside
_T35 1438-1443 FMAID:68646 denotes cells
_T36 1438-1443 FMAID:169002 denotes cells
_T37 1550-1555 FMAID:68646 denotes cells
_T38 1550-1555 FMAID:169002 denotes cells
_T39 1676-1687 FMAID:82816 denotes ganglioside
_T40 1676-1687 FMAID:196811 denotes ganglioside

uniprot-human

Id Subject Object Predicate Lexical cue
T1 265-267 http://www.uniprot.org/uniprot/P03372 denotes ER
T2 725-727 http://www.uniprot.org/uniprot/P03372 denotes ER

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 265-267 http://www.uniprot.org/uniprot/P19785 denotes ER
T2 725-727 http://www.uniprot.org/uniprot/P19785 denotes ER

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 991-999 http://purl.bioontology.org/ontology/STY/T033 denotes findings
T2 1438-1443 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 1550-1555 http://purl.bioontology.org/ontology/STY/T025 denotes cells

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-162 Sentence denotes Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA.
TextSentencer_T2 163-355 Sentence denotes Brefeldin A reversibly disassembles the Golgi complex, causing mixing of the Golgi cisternae with the ER while the trans Golgi network persists as part of a separate endosomal membrane system.
TextSentencer_T3 356-513 Sentence denotes Because of this compartmental separation, Brefeldin A treatment has been used to map the sub-Golgi locations of several Golgi enzymes including GM2 synthase.
TextSentencer_T4 514-750 Sentence denotes We previously proposed that GM2 synthase might be located in a distal portion of the Golgi complex which in the presence of Brefeldin A would be separated from the substrate ganglioside GM3 present in the mixed ER-Golgi membrane system.
TextSentencer_T5 751-976 Sentence denotes In the present study we show using GM2 synthase chimeras that GM2 synthesis was blocked by Brefeldin A when GM2 synthase was distributed throughout all Golgi subcompartments or even when it was restricted to the medial Golgi.
TextSentencer_T6 977-1164 Sentence denotes Because these findings opposed our speculation regarding a distal location of this enzyme, we sought an alternative explanation for the inhibition of ganglioside synthesis by Brefeldin A.
TextSentencer_T7 1165-1279 Sentence denotes However, Brefeldin A did not degrade GM2 synthase, prevent its homodimerization, or inhibit its in vitro activity.
TextSentencer_T8 1280-1444 Sentence denotes Brefeldin A did result in the conversion of a portion of membrane bound GM2 synthase into a soluble form which has minimal capability to produce GM2 in whole cells.
TextSentencer_T9 1445-1587 Sentence denotes However, this conversion was not sufficient to explain the nearly total loss of GM2 production in intact cells in the presence of Brefeldin A.
TextSentencer_T10 1588-1752 Sentence denotes Nevertheless, the results of this study indicate that Brefeldin A-induced inhibition of ganglioside synthesis cannot be used to deduce the location of GM2 synthase.
T1 0-162 Sentence denotes Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA.
T2 163-355 Sentence denotes Brefeldin A reversibly disassembles the Golgi complex, causing mixing of the Golgi cisternae with the ER while the trans Golgi network persists as part of a separate endosomal membrane system.
T3 356-513 Sentence denotes Because of this compartmental separation, Brefeldin A treatment has been used to map the sub-Golgi locations of several Golgi enzymes including GM2 synthase.
T4 514-750 Sentence denotes We previously proposed that GM2 synthase might be located in a distal portion of the Golgi complex which in the presence of Brefeldin A would be separated from the substrate ganglioside GM3 present in the mixed ER-Golgi membrane system.
T5 751-1279 Sentence denotes In the present study we show using GM2 synthase chimeras that GM2 synthesis was blocked by Brefeldin A when GM2 synthase was distributed throughout all Golgi subcompartments or even when it was restricted to the medial Golgi. Because these findings opposed our speculation regarding a distal location of this enzyme, we sought an alternative explanation for the inhibition of ganglioside synthesis by Brefeldin A. However, Brefeldin A did not degrade GM2 synthase, prevent its homodimerization, or inhibit its in vitro activity.
T6 1280-1444 Sentence denotes Brefeldin A did result in the conversion of a portion of membrane bound GM2 synthase into a soluble form which has minimal capability to produce GM2 in whole cells.
T7 1445-1752 Sentence denotes However, this conversion was not sufficient to explain the nearly total loss of GM2 production in intact cells in the presence of Brefeldin A. Nevertheless, the results of this study indicate that Brefeldin A-induced inhibition of ganglioside synthesis cannot be used to deduce the location of GM2 synthase.
T1 0-162 Sentence denotes Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA.
T2 163-355 Sentence denotes Brefeldin A reversibly disassembles the Golgi complex, causing mixing of the Golgi cisternae with the ER while the trans Golgi network persists as part of a separate endosomal membrane system.
T3 356-513 Sentence denotes Because of this compartmental separation, Brefeldin A treatment has been used to map the sub-Golgi locations of several Golgi enzymes including GM2 synthase.
T4 514-750 Sentence denotes We previously proposed that GM2 synthase might be located in a distal portion of the Golgi complex which in the presence of Brefeldin A would be separated from the substrate ganglioside GM3 present in the mixed ER-Golgi membrane system.
T5 751-976 Sentence denotes In the present study we show using GM2 synthase chimeras that GM2 synthesis was blocked by Brefeldin A when GM2 synthase was distributed throughout all Golgi subcompartments or even when it was restricted to the medial Golgi.
T6 977-1164 Sentence denotes Because these findings opposed our speculation regarding a distal location of this enzyme, we sought an alternative explanation for the inhibition of ganglioside synthesis by Brefeldin A.
T7 1165-1279 Sentence denotes However, Brefeldin A did not degrade GM2 synthase, prevent its homodimerization, or inhibit its in vitro activity.
T8 1280-1444 Sentence denotes Brefeldin A did result in the conversion of a portion of membrane bound GM2 synthase into a soluble form which has minimal capability to produce GM2 in whole cells.
T9 1445-1587 Sentence denotes However, this conversion was not sufficient to explain the nearly total loss of GM2 production in intact cells in the presence of Brefeldin A.
T10 1588-1752 Sentence denotes Nevertheless, the results of this study indicate that Brefeldin A-induced inhibition of ganglioside synthesis cannot be used to deduce the location of GM2 synthase.

GO-BP

Id Subject Object Predicate Lexical cue
T1 48-69 http://purl.obolibrary.org/obo/GO_0001574 denotes ganglioside synthesis
T2 1127-1148 http://purl.obolibrary.org/obo/GO_0001574 denotes ganglioside synthesis
T3 1676-1697 http://purl.obolibrary.org/obo/GO_0001574 denotes ganglioside synthesis
T4 60-69 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T5 145-154 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T6 817-826 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T7 1139-1148 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T8 1688-1697 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T9 186-208 http://purl.obolibrary.org/obo/GO_0090166 denotes disassembles the Golgi
T10 1194-1201 http://purl.obolibrary.org/obo/GO_0009056 denotes degrade

GO-CC

Id Subject Object Predicate Lexical cue
T1 203-208 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T2 240-245 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T3 284-289 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T4 449-454 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T5 476-481 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T6 599-604 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T7 728-733 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T8 903-908 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T9 970-975 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi
T10 203-216 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi complex
T11 599-612 http://purl.obolibrary.org/obo/GO_0005794 denotes Golgi complex
T12 240-255 http://purl.obolibrary.org/obo/GO_0005795 denotes Golgi cisternae
T13 240-255 http://purl.obolibrary.org/obo/GO_0031985 denotes Golgi cisternae
T14 246-267 http://purl.obolibrary.org/obo/GO_0005788 denotes cisternae with the ER
T15 265-267 http://purl.obolibrary.org/obo/GO_0005783 denotes ER
T16 725-727 http://purl.obolibrary.org/obo/GO_0005783 denotes ER
T17 278-297 http://purl.obolibrary.org/obo/GO_0032588 denotes trans Golgi network
T18 278-297 http://purl.obolibrary.org/obo/GO_0005802 denotes trans Golgi network
T19 329-338 http://purl.obolibrary.org/obo/GO_0005768 denotes endosomal
T20 329-347 http://purl.obolibrary.org/obo/GO_0010008 denotes endosomal membrane
T21 339-347 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T22 734-742 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T23 1337-1345 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T24 728-742 http://purl.obolibrary.org/obo/GO_0000139 denotes Golgi membrane
T25 1438-1443 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T26 1550-1555 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 963-969 http://purl.obolibrary.org/obo/UBERON_3010194 denotes medial

GlycoBiology-MAT

Id Subject Object Predicate Lexical cue
T1 963-969 http://purl.obolibrary.org/obo/MAT_0000490 denotes medial

GlyTouCan-IUPAC

Id Subject Object Predicate Lexical cue
GlycanIUPAC_T1 899-902 "http://rdf.glycoinfo.org/glycan/G41652MJ" denotes all
GlycanIUPAC_T2 899-902 "http://rdf.glycoinfo.org/glycan/G20761YC" denotes all
GlycanIUPAC_T3 899-902 "http://rdf.glycoinfo.org/glycan/G19807HM" denotes all
GlycanIUPAC_T4 899-902 "http://rdf.glycoinfo.org/glycan/G20351TE" denotes all
GlycanIUPAC_T5 899-902 "http://rdf.glycoinfo.org/glycan/G71957MR" denotes all
GlycanIUPAC_T6 899-902 "http://rdf.glycoinfo.org/glycan/G59040AE" denotes all
GlycanIUPAC_T7 899-902 "http://rdf.glycoinfo.org/glycan/G14987PW" denotes all
GlycanIUPAC_T8 899-902 "http://rdf.glycoinfo.org/glycan/G95064PC" denotes all
GlycanIUPAC_T9 899-902 "http://rdf.glycoinfo.org/glycan/G39143AQ" denotes all
GlycanIUPAC_T10 899-902 "http://rdf.glycoinfo.org/glycan/G65149OO" denotes all
GlycanIUPAC_T11 899-902 "http://rdf.glycoinfo.org/glycan/G02766SY" denotes all
GlycanIUPAC_T12 899-902 "http://rdf.glycoinfo.org/glycan/G26019KJ" denotes all
GlycanIUPAC_T13 899-902 "http://rdf.glycoinfo.org/glycan/G36429CZ" denotes all
GlycanIUPAC_T14 899-902 "http://rdf.glycoinfo.org/glycan/G89633TP" denotes all
GlycanIUPAC_T15 899-902 "http://rdf.glycoinfo.org/glycan/G28494FO" denotes all
GlycanIUPAC_T16 899-902 "http://rdf.glycoinfo.org/glycan/G06219CP" denotes all
GlycanIUPAC_T17 899-902 "http://rdf.glycoinfo.org/glycan/G44237SM" denotes all
GlycanIUPAC_T18 899-902 "http://rdf.glycoinfo.org/glycan/G57948RL" denotes all
GlycanIUPAC_T19 899-902 "http://rdf.glycoinfo.org/glycan/G64016DN" denotes all
GlycanIUPAC_T20 899-902 "http://rdf.glycoinfo.org/glycan/G14536PC" denotes all
GlycanIUPAC_T21 899-902 "http://rdf.glycoinfo.org/glycan/G14356FW" denotes all
GlycanIUPAC_T22 899-902 "http://rdf.glycoinfo.org/glycan/G34565UO" denotes all
GlycanIUPAC_T23 899-902 "http://rdf.glycoinfo.org/glycan/G67124MW" denotes all
GlycanIUPAC_T24 899-902 "http://rdf.glycoinfo.org/glycan/G71457ZU" denotes all
GlycanIUPAC_T25 899-902 "http://rdf.glycoinfo.org/glycan/G55228VZ" denotes all
GlycanIUPAC_T26 899-902 "http://rdf.glycoinfo.org/glycan/G31034MJ" denotes all
GlycanIUPAC_T27 899-902 "http://rdf.glycoinfo.org/glycan/G25776IP" denotes all
GlycanIUPAC_T28 899-902 "http://rdf.glycoinfo.org/glycan/G64442BV" denotes all
GlycanIUPAC_T29 899-902 "http://rdf.glycoinfo.org/glycan/G57018LE" denotes all
GlycanIUPAC_T30 899-902 "http://rdf.glycoinfo.org/glycan/G61761GX" denotes all
GlycanIUPAC_T31 899-902 "http://rdf.glycoinfo.org/glycan/G76318UX" denotes all
GlycanIUPAC_T32 899-902 "http://rdf.glycoinfo.org/glycan/G61906ER" denotes all
GlycanIUPAC_T33 899-902 "http://rdf.glycoinfo.org/glycan/G68723GR" denotes all
GlycanIUPAC_T34 899-902 "http://rdf.glycoinfo.org/glycan/G19540LE" denotes all
GlycanIUPAC_T35 899-902 "http://rdf.glycoinfo.org/glycan/G74944PO" denotes all
GlycanIUPAC_T36 899-902 "http://rdf.glycoinfo.org/glycan/G89489ZJ" denotes all
GlycanIUPAC_T37 899-902 "http://rdf.glycoinfo.org/glycan/G04434YU" denotes all
GlycanIUPAC_T38 899-902 "http://rdf.glycoinfo.org/glycan/G21450PB" denotes all
GlycanIUPAC_T39 899-902 "http://rdf.glycoinfo.org/glycan/G93629QY" denotes all
GlycanIUPAC_T40 899-902 "http://rdf.glycoinfo.org/glycan/G02603TR" denotes all
GlycanIUPAC_T41 899-902 "http://rdf.glycoinfo.org/glycan/G40280JP" denotes all
GlycanIUPAC_T42 899-902 "http://rdf.glycoinfo.org/glycan/G95259IC" denotes all
GlycanIUPAC_T43 899-902 "http://rdf.glycoinfo.org/glycan/G26900FE" denotes all
GlycanIUPAC_T44 899-902 "http://rdf.glycoinfo.org/glycan/G21346KK" denotes all
GlycanIUPAC_T45 899-902 "http://rdf.glycoinfo.org/glycan/G62509FF" denotes all
GlycanIUPAC_T46 899-902 "http://rdf.glycoinfo.org/glycan/G83932AK" denotes all
GlycanIUPAC_T47 899-902 "http://rdf.glycoinfo.org/glycan/G96978IB" denotes all
GlycanIUPAC_T48 899-902 "http://rdf.glycoinfo.org/glycan/G34275DN" denotes all
GlycanIUPAC_T49 899-902 "http://rdf.glycoinfo.org/glycan/G07071JF" denotes all
GlycanIUPAC_T50 899-902 "http://rdf.glycoinfo.org/glycan/G80639QD" denotes all
GlycanIUPAC_T51 899-902 "http://rdf.glycoinfo.org/glycan/G99460PJ" denotes all
GlycanIUPAC_T52 899-902 "http://rdf.glycoinfo.org/glycan/G22024BZ" denotes all
GlycanIUPAC_T53 899-902 "http://rdf.glycoinfo.org/glycan/G74097ZY" denotes all
GlycanIUPAC_T54 899-902 "http://rdf.glycoinfo.org/glycan/G84439YP" denotes all
GlycanIUPAC_T55 899-902 "http://rdf.glycoinfo.org/glycan/G52207WQ" denotes all
GlycanIUPAC_T56 899-902 "http://rdf.glycoinfo.org/glycan/G90695MS" denotes all
GlycanIUPAC_T57 899-902 "http://rdf.glycoinfo.org/glycan/G50398QX" denotes all
GlycanIUPAC_T58 899-902 "http://rdf.glycoinfo.org/glycan/G12166ZT" denotes all
GlycanIUPAC_T59 899-902 "http://rdf.glycoinfo.org/glycan/G48368BR" denotes all
GlycanIUPAC_T60 899-902 "http://rdf.glycoinfo.org/glycan/G57407RW" denotes all
GlycanIUPAC_T61 899-902 "http://rdf.glycoinfo.org/glycan/G00386TY" denotes all
GlycanIUPAC_T62 899-902 "http://rdf.glycoinfo.org/glycan/G18723JK" denotes all
GlycanIUPAC_T63 899-902 "http://rdf.glycoinfo.org/glycan/G93757OR" denotes all
GlycanIUPAC_T64 899-902 "http://rdf.glycoinfo.org/glycan/G29006SI" denotes all
GlycanIUPAC_T65 899-902 "http://rdf.glycoinfo.org/glycan/G03099OQ" denotes all
GlycanIUPAC_T66 899-902 "http://rdf.glycoinfo.org/glycan/G53739OW" denotes all
GlycanIUPAC_T67 899-902 "http://rdf.glycoinfo.org/glycan/G70440ZO" denotes all
GlycanIUPAC_T68 899-902 "http://rdf.glycoinfo.org/glycan/G29951RR" denotes all
GlycanIUPAC_T69 899-902 "http://rdf.glycoinfo.org/glycan/G58402TI" denotes all
GlycanIUPAC_T70 899-902 "http://rdf.glycoinfo.org/glycan/G39875TP" denotes all
GlycanIUPAC_T71 899-902 "http://rdf.glycoinfo.org/glycan/G83439QV" denotes all
GlycanIUPAC_T72 899-902 "http://rdf.glycoinfo.org/glycan/G41762RC" denotes all
GlycanIUPAC_T73 899-902 "http://rdf.glycoinfo.org/glycan/G91604UI" denotes all
GlycanIUPAC_T74 899-902 "http://rdf.glycoinfo.org/glycan/G88447WE" denotes all
GlycanIUPAC_T75 899-902 "http://rdf.glycoinfo.org/glycan/G93634BS" denotes all
GlycanIUPAC_T76 899-902 "http://rdf.glycoinfo.org/glycan/G02587BH" denotes all
GlycanIUPAC_T77 899-902 "http://rdf.glycoinfo.org/glycan/G43511MX" denotes all
GlycanIUPAC_T78 899-902 "http://rdf.glycoinfo.org/glycan/G64958DH" denotes all
GlycanIUPAC_T79 899-902 "http://rdf.glycoinfo.org/glycan/G30384TR" denotes all
GlycanIUPAC_T80 899-902 "http://rdf.glycoinfo.org/glycan/G15624EX" denotes all
GlycanIUPAC_T81 899-902 "http://rdf.glycoinfo.org/glycan/G22706ST" denotes all
GlycanIUPAC_T82 899-902 "http://rdf.glycoinfo.org/glycan/G57408PI" denotes all
GlycanIUPAC_T83 899-902 "http://rdf.glycoinfo.org/glycan/G86403XX" denotes all
GlycanIUPAC_T84 899-902 "http://rdf.glycoinfo.org/glycan/G78043YB" denotes all
GlycanIUPAC_T85 899-902 "http://rdf.glycoinfo.org/glycan/G18952JK" denotes all
GlycanIUPAC_T86 899-902 "http://rdf.glycoinfo.org/glycan/G49020ND" denotes all
GlycanIUPAC_T87 899-902 "http://rdf.glycoinfo.org/glycan/G63590YW" denotes all
GlycanIUPAC_T88 899-902 "http://rdf.glycoinfo.org/glycan/G22793KS" denotes all
GlycanIUPAC_T89 899-902 "http://rdf.glycoinfo.org/glycan/G64134SS" denotes all
GlycanIUPAC_T90 899-902 "http://rdf.glycoinfo.org/glycan/G17338HY" denotes all
GlycanIUPAC_T91 899-902 "http://rdf.glycoinfo.org/glycan/G99745XF" denotes all
GlycanIUPAC_T92 899-902 "http://rdf.glycoinfo.org/glycan/G27782HN" denotes all
GlycanIUPAC_T93 899-902 "http://rdf.glycoinfo.org/glycan/G57496DC" denotes all
GlycanIUPAC_T94 899-902 "http://rdf.glycoinfo.org/glycan/G93169WB" denotes all
GlycanIUPAC_T95 899-902 "http://rdf.glycoinfo.org/glycan/G05518TD" denotes all
GlycanIUPAC_T96 899-902 "http://rdf.glycoinfo.org/glycan/G62603DN" denotes all
GlycanIUPAC_T97 899-902 "http://rdf.glycoinfo.org/glycan/G59574FS" denotes all
GlycanIUPAC_T98 899-902 "http://rdf.glycoinfo.org/glycan/G47567WC" denotes all

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 963-969 http://purl.obolibrary.org/obo/UBERON_3010194 denotes medial

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 87-90 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T2 141-144 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T3 500-503 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T4 542-545 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T5 700-703 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T6 786-789 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T7 813-816 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T8 859-862 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T9 1202-1205 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T10 1352-1355 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T11 1425-1428 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T12 1525-1528 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T13 1739-1742 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 963-969 Body_part denotes medial http://purl.obolibrary.org/obo/MAT_0000490

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 87-90 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T2 141-144 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T3 500-503 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T4 542-545 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T5 700-703 Glycan denotes GM3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G91237TK
T6 786-789 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T7 813-816 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T8 859-862 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T9 1202-1205 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T10 1352-1355 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T11 1425-1428 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T12 1525-1528 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT
T13 1739-1742 Glycan denotes GM2 https://api.glycosmos.org/wurcs2image/latest/png/binary/G79389NT

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 203-216 Body_part denotes Golgi complex http://purl.obolibrary.org/obo/GO_0005794
T2 240-245 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T3 246-255 Body_part denotes cisternae http://purl.obolibrary.org/obo/UBERON_0004050
T4 284-289 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T5 339-347 Body_part denotes membrane http://purl.obolibrary.org/obo/UBERON_0000094
T6 449-454 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T7 476-481 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T8 599-612 Body_part denotes Golgi complex http://purl.obolibrary.org/obo/GO_0005794
T9 728-742 Body_part denotes Golgi membrane http://purl.obolibrary.org/obo/GO_0000139
T10 903-908 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T11 970-975 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T12 1337-1345 Body_part denotes membrane http://purl.obolibrary.org/obo/UBERON_0000094

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-162 Sentence denotes Reevaluating the effect of Brefeldin A (BFA) on ganglioside synthesis: the location of GM2 synthase cannot be deduced from the inhibition of GM2 synthesis by BFA.
T2 163-355 Sentence denotes Brefeldin A reversibly disassembles the Golgi complex, causing mixing of the Golgi cisternae with the ER while the trans Golgi network persists as part of a separate endosomal membrane system.
T3 356-513 Sentence denotes Because of this compartmental separation, Brefeldin A treatment has been used to map the sub-Golgi locations of several Golgi enzymes including GM2 synthase.
T4 514-750 Sentence denotes We previously proposed that GM2 synthase might be located in a distal portion of the Golgi complex which in the presence of Brefeldin A would be separated from the substrate ganglioside GM3 present in the mixed ER-Golgi membrane system.
T5 751-1279 Sentence denotes In the present study we show using GM2 synthase chimeras that GM2 synthesis was blocked by Brefeldin A when GM2 synthase was distributed throughout all Golgi subcompartments or even when it was restricted to the medial Golgi. Because these findings opposed our speculation regarding a distal location of this enzyme, we sought an alternative explanation for the inhibition of ganglioside synthesis by Brefeldin A. However, Brefeldin A did not degrade GM2 synthase, prevent its homodimerization, or inhibit its in vitro activity.
T6 1280-1444 Sentence denotes Brefeldin A did result in the conversion of a portion of membrane bound GM2 synthase into a soluble form which has minimal capability to produce GM2 in whole cells.
T7 1445-1752 Sentence denotes However, this conversion was not sufficient to explain the nearly total loss of GM2 production in intact cells in the presence of Brefeldin A. Nevertheless, the results of this study indicate that Brefeldin A-induced inhibition of ganglioside synthesis cannot be used to deduce the location of GM2 synthase.

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 203-216 Body_part denotes Golgi complex FMA:63843
T2 240-255 Body_part denotes Golgi cisternae FMA:61750
T3 278-297 Body_part denotes trans Golgi network FMA:61756
T4 329-338 Body_part denotes endosomal FMA:67180
T5 599-612 Body_part denotes Golgi complex FMA:63843
T6 728-742 Body_part denotes Golgi membrane FMA:0326754

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 963-969 Body_part denotes medial http://purl.obolibrary.org/obo/MAT_0000490

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 203-216 Body_part denotes Golgi complex http://purl.obolibrary.org/obo/GO_0005794
T2 240-245 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T3 246-255 Body_part denotes cisternae http://purl.obolibrary.org/obo/UBERON_0004050
T4 284-289 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T5 339-347 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T8 449-454 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T9 476-481 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T10 599-612 Body_part denotes Golgi complex http://purl.obolibrary.org/obo/GO_0005794
T11 728-742 Body_part denotes Golgi membrane http://purl.obolibrary.org/obo/GO_0000139
T12 903-908 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T13 970-975 Body_part denotes Golgi http://purl.obolibrary.org/obo/GO_0005794
T14 1337-1345 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158