PubMed:10358178
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 9-24 | protein | denotes | NF-ATc isoforms |
| T2 | 87-100 | cell_type | denotes | T lymphocytes |
| T3 | 106-126 | protein | denotes | transcription factor |
| T4 | 127-133 | protein | denotes | NF-ATc |
| T5 | 167-180 | cell_type | denotes | T lymphocytes |
| T6 | 185-208 | cell_type | denotes | embryonic cardiac cells |
| T7 | 371-384 | cell_type | denotes | naive T cells |
| T8 | 399-413 | protein | denotes | NF-ATc isoform |
| T9 | 417-433 | cell_type | denotes | effector T cells |
| T10 | 468-484 | protein | denotes | isoform NF-ATc/A |
| T11 | 513-523 | protein | denotes | C terminus |
| T12 | 546-547 | protein | denotes | B |
| T13 | 552-553 | protein | denotes | C |
| T14 | 656-697 | protein | denotes | strong N-terminal trans-activation domain |
| T15 | 699-704 | protein | denotes | TAD-A |
| T16 | 735-750 | protein | denotes | NF-ATc isoforms |
| T17 | 752-760 | protein | denotes | NF-ATc/C |
| T18 | 779-802 | protein | denotes | trans-activation domain |
| T19 | 804-809 | protein | denotes | TAD-B |
| T20 | 857-864 | cell_type | denotes | T cells |
| T21 | 893-898 | protein | denotes | TAD-A |
| T22 | 928-933 | protein | denotes | TAD-B |
| T23 | 947-952 | protein | denotes | TAD-A |
| T24 | 954-959 | protein | denotes | TAD-B |
| T25 | 1001-1060 | cell_line | denotes | 12-O-tetradecanoyl 12-phorbol 13-acetate-stimulated T cells |
| T26 | 1104-1112 | protein | denotes | NF-ATc/B |
| T27 | 1178-1193 | protein | denotes | NF-ATc/B and -C |
| T28 | 1240-1259 | cell_type | denotes | naive T lymphocytes |
| T29 | 1269-1284 | protein | denotes | NF-ATc/B and -C |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-101 | Sentence | denotes | Multiple NF-ATc isoforms with individual transcriptional properties are synthesized in T lymphocytes. |
| S2 | 102-250 | Sentence | denotes | The transcription factor NF-ATc that controls gene expression in T lymphocytes and embryonic cardiac cells is expressed in three prominent isoforms. |
| S3 | 251-434 | Sentence | denotes | This is due to alternative splice/polyadenylation events that lead to the predominant synthesis of two long isoforms in naive T cells and a shorter NF-ATc isoform in effector T cells. |
| S4 | 435-618 | Sentence | denotes | Whereas the previously described isoform NF-ATc/A contains a relatively short C terminus, the longer isoforms, B and C, span extra C-terminal peptides of 128 and 246 aa, respectively. |
| S5 | 619-837 | Sentence | denotes | We show here that in addition to the strong N-terminal trans-activation domain, TAD-A, which is common to all three NF-ATc isoforms, NF-ATc/C contains a second trans-activation domain, TAD-B, in its C-terminal peptide. |
| S6 | 838-1061 | Sentence | denotes | Various stimuli of T cells that induce the activity of TAD-A also enhance the activity of TAD-B, but, unlike TAD-A, TAD-B remains unphosphorylated by protein from 12-O-tetradecanoyl 12-phorbol 13-acetate-stimulated T cells. |
| S7 | 1062-1157 | Sentence | denotes | The shorter C-terminal peptide of isoform NF-ATc/B exerts a suppressive transcriptional effect. |
| S8 | 1158-1315 | Sentence | denotes | These properties of NF-ATc/B and -C might be of importance for gene regulation in naive T lymphocytes in which NF-ATc/B and -C are predominantly synthesized. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 87-100 | NP | denotes | T lymphocytes |
| C2 | 102-133 | NP | denotes | The transcription factor NF-ATc |
| C3 | 134-138 | NP | denotes | that |
| C4 | 167-180 | NP | denotes | T lymphocytes |
| C5 | 225-249 | NP | denotes | three prominent isoforms |
| C6 | 266-307 | NP | denotes | alternative splice/polyadenylation events |
| C7 | 308-312 | NP | denotes | that |
| C8 | 371-384 | NP | denotes | naive T cells |
| C9 | 525-544 | NP | denotes | the longer isoforms |
| C10 | 546-553 | NP | denotes | B and C |
| C11 | 652-697 | NP | denotes | the strong N-terminal trans-activation domain |
| C12 | 699-704 | NP | denotes | TAD-A |
| C13 | 706-711 | NP | denotes | which |
| C14 | 725-750 | NP | denotes | all three NF-ATc isoforms |
| C15 | 752-760 | NP | denotes | NF-ATc/C |
| C16 | 770-802 | NP | denotes | a second trans-activation domain |
| C17 | 804-809 | NP | denotes | TAD-B |
| C18 | 814-817 | NP | denotes | its |
| C20 | 857-864 | NP | denotes | T cells |
| C19 | 838-864 | NP | denotes | Various stimuli of T cells |
| C21 | 865-869 | NP | denotes | that |
| C22 | 893-898 | NP | denotes | TAD-A |
| C23 | 928-933 | NP | denotes | TAD-B |
| C24 | 947-952 | NP | denotes | TAD-A |
| C25 | 954-959 | NP | denotes | TAD-B |
| C26 | 1178-1193 | NP | denotes | NF-ATc/B and -C |
| C28 | 1240-1259 | NP | denotes | naive T lymphocytes |
| C27 | 1221-1259 | NP | denotes | gene regulation in naive T lymphocytes |
| C29 | 1263-1268 | NP | denotes | which |
| C30 | 1269-1284 | NP | denotes | NF-ATc/B and -C |
| R1 | C3 | C2 | coref-relat | that,The transcription factor NF-ATc |
| R2 | C4 | C1 | coref-ident | T lymphocytes,T lymphocytes |
| R3 | C7 | C6 | coref-relat | that,alternative splice/polyadenylation events |
| R4 | C10 | C9 | coref-appos | B and C,the longer isoforms |
| R5 | C12 | C11 | coref-appos | TAD-A,the strong N-terminal trans-activation domain |
| R6 | C13 | C11 | coref-relat | which,the strong N-terminal trans-activation domain |
| R7 | C14 | C5 | coref-ident | all three NF-ATc isoforms,three prominent isoforms |
| R8 | C17 | C16 | coref-appos | TAD-B,a second trans-activation domain |
| R9 | C18 | C15 | coref-pron | its,NF-ATc/C |
| R10 | C20 | C4 | coref-ident | T cells,T lymphocytes |
| R11 | C21 | C19 | coref-relat | that,Various stimuli of T cells |
| R12 | C22 | C11 | coref-ident | TAD-A,the strong N-terminal trans-activation domain |
| R13 | C23 | C16 | coref-ident | TAD-B,a second trans-activation domain |
| R14 | C24 | C22 | coref-ident | TAD-A,TAD-A |
| R15 | C25 | C23 | coref-ident | TAD-B,TAD-B |
| R16 | C28 | C8 | coref-ident | naive T lymphocytes,naive T cells |
| R17 | C29 | C27 | coref-relat | which,gene regulation in naive T lymphocytes |
| R18 | C30 | C26 | coref-ident | NF-ATc/B and -C,NF-ATc/B and -C |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 9-24 | protein_family_or_group | denotes | NF-ATc isoforms |
| T2 | 41-67 | other_name | denotes | transcriptional properties |
| T3 | 87-100 | cell_type | denotes | T lymphocytes |
| T4 | 106-126 | protein_family_or_group | denotes | transcription factor |
| T5 | 127-133 | protein_molecule | denotes | NF-ATc |
| T6 | 148-163 | other_name | denotes | gene expression |
| T7 | 167-180 | cell_type | denotes | T lymphocytes |
| T8 | 185-208 | cell_type | denotes | embryonic cardiac cells |
| T9 | 278-307 | other_name | denotes | splice/polyadenylation events |
| T10 | 371-384 | cell_type | denotes | naive T cells |
| T11 | 399-405 | protein_molecule | denotes | NF-ATc |
| T12 | 417-433 | cell_type | denotes | effector T cells |
| T13 | 468-475 | protein_molecule | denotes | isoform |
| T14 | 476-482 | protein_molecule | denotes | NF-ATc |
| T15 | 513-523 | protein_domain_or_region | denotes | C terminus |
| T16 | 546-547 | protein_molecule | denotes | B |
| T17 | 552-553 | protein_molecule | denotes | C |
| T18 | 560-585 | peptide | denotes | extra C-terminal peptides |
| T19 | 656-697 | protein_domain_or_region | denotes | strong N-terminal trans-activation domain |
| T20 | 699-704 | protein_domain_or_region | denotes | TAD-A |
| T21 | 735-741 | protein_molecule | denotes | NF-ATc |
| T22 | 752-758 | protein_molecule | denotes | NF-ATc |
| T23 | 779-802 | protein_domain_or_region | denotes | trans-activation domain |
| T24 | 804-809 | protein_domain_or_region | denotes | TAD-B |
| T25 | 818-836 | peptide | denotes | C-terminal peptide |
| T26 | 857-864 | cell_type | denotes | T cells |
| T27 | 893-898 | protein_domain_or_region | denotes | TAD-A |
| T28 | 928-933 | protein_domain_or_region | denotes | TAD-B |
| T29 | 947-952 | protein_domain_or_region | denotes | TAD-A |
| T30 | 954-959 | protein_domain_or_region | denotes | TAD-B |
| T31 | 1001-1041 | other_organic_compound | denotes | 12-O-tetradecanoyl 12-phorbol 13-acetate |
| T32 | 1053-1060 | cell_type | denotes | T cells |
| T33 | 1074-1092 | peptide | denotes | C-terminal peptide |
| T34 | 1104-1110 | protein_molecule | denotes | NF-ATc |
| T35 | 1134-1156 | other_name | denotes | transcriptional effect |
| T36 | 1221-1236 | other_name | denotes | gene regulation |
| T37 | 1240-1245 | cell_type | denotes | naive |
| T38 | 1246-1259 | cell_type | denotes | T lymphocytes |