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PubMed:10352279 JSONTXT

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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-152 Sentence denotes CD28 costimulation augments IL-2 secretion of activated lamina propria T cells by increasing mRNA stability without enhancing IL-2 gene transactivation.
T2 153-257 Sentence denotes The pathways leading to activation in lamina propria (LP) T cells are different from peripheral T cells.
T3 258-340 Sentence denotes LP T cells exhibit enhanced IL-2 secretion when activated through the CD2 pathway.
T4 341-411 Sentence denotes Coligation of CD28 leads to synergistic enhancement of IL-2 secretion.
T5 412-646 Sentence denotes Previous studies have characterized the CD28 augmentation of TCR-mediated signaling in peripheral blood T cells through transcriptional activation of an IL-2 promoter CD28 response element (CD28RE), along with enhanced mRNA stability.
T6 647-770 Sentence denotes This study characterized molecular events involved in CD28 costimulation of IL-2 production in LP mononuclear cells (LPMC).
T7 771-895 Sentence denotes LPMC exhibited increased IL-2 production in response to CD28 costimulation, compared with cells activated through CD2 alone.
T8 896-1008 Sentence denotes IL-2 secretion was paralleled by increased expression of IL-2 mRNA, resulting from enhanced IL-2 mRNA stability.
T9 1009-1289 Sentence denotes In contrast to transcriptional activation in PBMC, EMSA revealed that CD28 coligation of CD2-activated LPMC does not result in increased binding of trans-factors to the CD28RE, nor did Western blots detect changes in I-kappaBalpha or I-kappaBbeta levels following CD28 coligation.
T10 1290-1411 Sentence denotes Furthermore, CD28 coligation fails to enhance IL-2 promoter-reporter or RE/AP construct expression in CD2-activated LPMC.
T11 1412-1641 Sentence denotes The results reported herein indicate that the molecular mechanisms involved in CD28 cosignaling and regulation of IL-2 secretion in LP T cells are unique to that compartment and differ from those seen in peripheral blood T cells.
T12 1642-1816 Sentence denotes These observations suggest a biological significance for different mechanisms of IL-2 activation in initiation and maintenance of the cytokine repertoire found in the mucosa.
T1 0-152 Sentence denotes CD28 costimulation augments IL-2 secretion of activated lamina propria T cells by increasing mRNA stability without enhancing IL-2 gene transactivation.
T2 153-257 Sentence denotes The pathways leading to activation in lamina propria (LP) T cells are different from peripheral T cells.
T3 258-340 Sentence denotes LP T cells exhibit enhanced IL-2 secretion when activated through the CD2 pathway.
T4 341-411 Sentence denotes Coligation of CD28 leads to synergistic enhancement of IL-2 secretion.
T5 412-646 Sentence denotes Previous studies have characterized the CD28 augmentation of TCR-mediated signaling in peripheral blood T cells through transcriptional activation of an IL-2 promoter CD28 response element (CD28RE), along with enhanced mRNA stability.
T6 647-770 Sentence denotes This study characterized molecular events involved in CD28 costimulation of IL-2 production in LP mononuclear cells (LPMC).
T7 771-895 Sentence denotes LPMC exhibited increased IL-2 production in response to CD28 costimulation, compared with cells activated through CD2 alone.
T8 896-1008 Sentence denotes IL-2 secretion was paralleled by increased expression of IL-2 mRNA, resulting from enhanced IL-2 mRNA stability.
T9 1009-1289 Sentence denotes In contrast to transcriptional activation in PBMC, EMSA revealed that CD28 coligation of CD2-activated LPMC does not result in increased binding of trans-factors to the CD28RE, nor did Western blots detect changes in I-kappaBalpha or I-kappaBbeta levels following CD28 coligation.
T10 1290-1411 Sentence denotes Furthermore, CD28 coligation fails to enhance IL-2 promoter-reporter or RE/AP construct expression in CD2-activated LPMC.
T11 1412-1641 Sentence denotes The results reported herein indicate that the molecular mechanisms involved in CD28 cosignaling and regulation of IL-2 secretion in LP T cells are unique to that compartment and differ from those seen in peripheral blood T cells.
T12 1642-1816 Sentence denotes These observations suggest a biological significance for different mechanisms of IL-2 activation in initiation and maintenance of the cytokine repertoire found in the mucosa.

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-4 protein denotes CD28
T2 28-32 protein denotes IL-2
T3 126-130 protein denotes IL-2
T4 191-218 cell_type denotes lamina propria (LP) T cells
T5 238-256 cell_type denotes peripheral T cells
T6 258-268 cell_type denotes LP T cells
T7 286-290 protein denotes IL-2
T8 328-331 protein denotes CD2
T9 355-359 protein denotes CD28
T10 396-400 protein denotes IL-2
T11 452-456 protein denotes CD28
T12 473-476 protein denotes TCR
T13 499-523 cell_type denotes peripheral blood T cells
T14 565-569 protein denotes IL-2
T15 579-600 DNA denotes CD28 response element
T16 602-608 DNA denotes CD28RE
T17 701-705 protein denotes CD28
T18 723-727 protein denotes IL-2
T19 742-769 cell_type denotes LP mononuclear cells (LPMC)
T20 771-775 cell_type denotes LPMC
T21 796-800 protein denotes IL-2
T22 827-831 protein denotes CD28
T23 885-888 protein denotes CD2
T24 896-900 protein denotes IL-2
T25 953-962 RNA denotes IL-2 mRNA
T26 988-997 RNA denotes IL-2 mRNA
T27 1054-1058 cell_type denotes PBMC
T28 1079-1083 protein denotes CD28
T29 1098-1116 cell_type denotes CD2-activated LPMC
T30 1178-1184 DNA denotes CD28RE
T31 1226-1239 protein denotes I-kappaBalpha
T32 1243-1255 protein denotes I-kappaBbeta
T33 1273-1277 protein denotes CD28
T34 1303-1307 protein denotes CD28
T35 1336-1358 DNA denotes IL-2 promoter-reporter
T36 1362-1367 protein denotes RE/AP
T37 1392-1410 cell_type denotes CD2-activated LPMC
T38 1491-1495 protein denotes CD28
T39 1526-1530 protein denotes IL-2
T40 1544-1554 cell_type denotes LP T cells
T41 1616-1640 cell_type denotes peripheral blood T cells
T42 1723-1727 protein denotes IL-2
T43 1776-1795 protein denotes cytokine repertoire

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-4 protein_molecule denotes CD28
T2 28-32 protein_molecule denotes IL-2
T3 126-130 protein_molecule denotes IL-2
T4 191-218 cell_type denotes lamina propria (LP) T cells
T5 238-256 cell_type denotes peripheral T cells
T6 258-268 cell_type denotes LP T cells
T7 286-290 protein_molecule denotes IL-2
T8 328-331 protein_molecule denotes CD2
T9 355-359 protein_molecule denotes CD28
T10 396-400 protein_molecule denotes IL-2
T11 452-456 protein_molecule denotes CD28
T12 473-476 protein_family_or_group denotes TCR
T13 499-523 cell_type denotes peripheral blood T cells
T14 532-558 other_name denotes transcriptional activation
T15 565-569 protein_molecule denotes IL-2
T16 579-583 protein_molecule denotes CD28
T17 602-608 DNA_domain_or_region denotes CD28RE
T18 701-705 protein_molecule denotes CD28
T19 723-727 protein_molecule denotes IL-2
T20 742-764 cell_type denotes LP mononuclear cells (
T21 764-768 cell_type denotes LPMC
T22 771-775 cell_type denotes LPMC
T23 796-800 protein_molecule denotes IL-2
T24 827-831 protein_molecule denotes CD28
T25 885-888 protein_molecule denotes CD2
T26 896-900 protein_molecule denotes IL-2
T27 953-957 protein_molecule denotes IL-2
T28 988-992 protein_molecule denotes IL-2
T29 1054-1058 cell_type denotes PBMC
T30 1060-1064 other_name denotes EMSA
T31 1079-1083 protein_molecule denotes CD28
T32 1098-1101 protein_molecule denotes CD2
T33 1112-1116 cell_type denotes LPMC
T34 1178-1184 DNA_domain_or_region denotes CD28RE
T35 1194-1207 other_name denotes Western blots
T36 1226-1239 protein_molecule denotes I-kappaBalpha
T37 1243-1255 protein_molecule denotes I-kappaBbeta
T38 1273-1277 protein_molecule denotes CD28
T39 1303-1307 protein_molecule denotes CD28
T40 1336-1340 protein_molecule denotes IL-2
T41 1362-1367 protein_molecule denotes RE/AP
T42 1392-1395 protein_molecule denotes CD2
T43 1406-1410 cell_type denotes LPMC
T44 1458-1478 other_name denotes molecular mechanisms
T45 1491-1495 protein_molecule denotes CD28
T46 1526-1530 protein_molecule denotes IL-2
T47 1544-1554 cell_type denotes LP T cells
T48 1616-1640 cell_type denotes peripheral blood T cells
T49 1723-1727 protein_molecule denotes IL-2
T50 1776-1795 protein_family_or_group denotes cytokine repertoire
T51 1809-1815 tissue denotes mucosa

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-4 cui:C1332709 denotes CD28
E2-ti-1 28-32 cui:C0879590 denotes IL-2
E3-ti-1 33-42 cui:C0015283 denotes secretion
E4-ti-1 46-55 cui:C1515877 denotes activated
E5-ti-1 56-70 cui:C1179187 denotes lamina propria
E6-ti-1 71-78 cui:C0039194 denotes T cells
E7-ti-1 82-92 cui:C0442808 denotes increasing
E8-ti-1 93-107 cui:C1257757 denotes mRNA stability
E9-ti-1 126-135 cui:C0879590 denotes IL-2 gene
E10-ti-1 136-151 cui:C0040624 denotes transactivation
T1 56-78 PART_OF denotes lamina propria T cells
T2 43-45 PART_OF denotes of
E1-ab-1 191-205 cui:C1179187 denotes lamina propria
E2-ab-1 211-218 cui:C0039194 denotes T cells
E3-ab-1 223-232 cui:C1547020 denotes different
E4-ab-1 238-248 cui:C0205100 denotes peripheral
E5-ab-1 249-256 cui:C0039194 denotes T cells
T3 191-218 PART_OF denotes lamina propria (LP) T cells
E1-ab-2 258-260 cui:C1179187 denotes LP
E2-ab-2 261-268 cui:C0039194 denotes T cells
E3-ab-2 286-290 cui:C0879590 denotes IL-2
E4-ab-2 291-300 cui:C0015283 denotes secretion
E5-ab-2 328-331 cui:C1367475 denotes CD2
E6-ab-2 332-339 cui:C0243123 denotes pathway
T4 258-268 PART_OF denotes LP T cells
T5 306-315 STIMULATES denotes activated
E1-ab-3 355-359 cui:C1332709 denotes CD28
E2-ab-3 396-400 cui:C0879590 denotes IL-2
E3-ab-3 401-410 cui:C0015283 denotes secretion
T6 381-392 STIMULATES denotes enhancement
E1-ab-4 412-420 cui:C0205156 denotes Previous
E2-ab-4 421-428 cui:C0008972 denotes studies
E3-ab-4 452-456 cui:C1332709 denotes CD28
E4-ab-4 457-469 cui:C1293122 denotes augmentation
E5-ab-4 473-476 cui:C0034790 denotes TCR
E6-ab-4 477-485 cui:C0086597 denotes mediated
E7-ab-4 486-495 cui:C0037083 denotes signaling
E8-ab-4 499-523 cui:C0005773 denotes peripheral blood T cells
E9-ab-4 532-558 cui:C0162493 denotes transcriptional activation
E10-ab-4 565-569 cui:C0879590 denotes IL-2
E11-ab-4 579-583 cui:C1332709 denotes CD28
E12-ab-4 584-600 cui:C0600508 denotes response element
E13-ab-4 631-645 cui:C1257757 denotes mRNA stability
T7 477-485 AFFECTS denotes mediated
E1-ab-5 652-657 cui:C0008972 denotes study
E2-ab-5 672-681 cui:C1521991 denotes molecular
E3-ab-5 682-688 cui:C0441471 denotes events
E4-ab-5 701-705 cui:C1332709 denotes CD28
E5-ab-5 723-727 cui:C0879590 denotes IL-2
E6-ab-5 728-738 cui:C0033268 denotes production
E7-ab-5 742-744 cui:C1179187 denotes LP
E8-ab-5 745-762 cui:C0806987 denotes mononuclear cells
T8 742-762 PART_OF denotes LP mononuclear cells
T9 739-741 LOCATION_OF denotes in
E1-ab-6 786-795 cui:C0205217 denotes increased
E2-ab-6 796-800 cui:C0879590 denotes IL-2
E3-ab-6 801-811 cui:C0033268 denotes production
E4-ab-6 815-823 cui:C0871261 denotes response
E5-ab-6 827-831 cui:C1332709 denotes CD28
E6-ab-6 861-866 cui:C0007634 denotes cells
E7-ab-6 885-888 cui:C1367475 denotes CD2
T10 867-876 STIMULATES denotes activated
E1-ab-7 896-900 cui:C0879590 denotes IL-2
E2-ab-7 901-910 cui:C0015283 denotes secretion
E3-ab-7 929-938 cui:C0205217 denotes increased
E4-ab-7 939-949 cui:C0185117 denotes expression
E5-ab-7 953-957 cui:C0879590 denotes IL-2
E6-ab-7 958-962 cui:C0035696 denotes mRNA
E7-ab-7 988-992 cui:C0879590 denotes IL-2
E8-ab-7 993-1007 cui:C1257757 denotes mRNA stability
E1-ab-8 1024-1050 cui:C0162493 denotes transcriptional activation
E2-ab-8 1060-1064 cui:C0872343 denotes EMSA
E3-ab-8 1079-1083 cui:C1332709 denotes CD28
E4-ab-8 1098-1101 cui:C1367475 denotes CD2
E5-ab-8 1102-1111 cui:C1515877 denotes activated
E6-ab-8 1122-1125 cui:C1518422 denotes not
E7-ab-8 1136-1145 cui:C0205217 denotes increased
E8-ab-8 1163-1170 cui:C1521761 denotes factors
E9-ab-8 1178-1184 cui:C1332709 denotes CD28RE
E10-ab-8 1178-1184 cui:C0600508 denotes CD28RE
E11-ab-8 1194-1207 cui:C0949466 denotes Western blots
E12-ab-8 1215-1222 cui:C0392747 denotes changes
E13-ab-8 1256-1262 cui:C0441889 denotes levels
E14-ab-8 1273-1277 cui:C1332709 denotes CD28
E1-ab-9 1303-1307 cui:C1332709 denotes CD28
E2-ab-9 1336-1340 cui:C0879590 denotes IL-2
E3-ab-9 1350-1358 cui:C0335038 denotes reporter
E4-ab-9 1378-1388 cui:C0185117 denotes expression
E5-ab-9 1392-1395 cui:C1367475 denotes CD2
E6-ab-9 1396-1405 cui:C1515877 denotes activated
E1-ab-10 1416-1423 cui:C1274040 denotes results
E2-ab-10 1458-1467 cui:C1521991 denotes molecular
E3-ab-10 1468-1478 cui:C0441712 denotes mechanisms
E4-ab-10 1491-1495 cui:C1332709 denotes CD28
E5-ab-10 1512-1522 cui:C0851285 denotes regulation
E6-ab-10 1526-1530 cui:C0879590 denotes IL-2
E7-ab-10 1531-1540 cui:C0015283 denotes secretion
E8-ab-10 1544-1546 cui:C1179187 denotes LP
E9-ab-10 1547-1554 cui:C0039194 denotes T cells
E10-ab-10 1574-1585 cui:C1185625 denotes compartment
E11-ab-10 1616-1640 cui:C0005773 denotes peripheral blood T cells
T11 1544-1554 PART_OF denotes LP T cells
T12 1541-1543 LOCATION_OF denotes in
T13 1613-1615 LOCATION_OF denotes in
E1-ab-11 1671-1681 cui:C0205460 denotes biological
E2-ab-11 1682-1694 cui:C0750502 denotes significance
E3-ab-11 1699-1708 cui:C1547020 denotes different
E4-ab-11 1709-1719 cui:C0441712 denotes mechanisms
E5-ab-11 1723-1727 cui:C0879590 denotes IL-2
E6-ab-11 1757-1768 cui:C0024501 denotes maintenance
E7-ab-11 1776-1784 cui:C0079189 denotes cytokine
E8-ab-11 1809-1815 cui:C0026724 denotes mucosa
R1 E6-ti-1 T1 subjectOf T cells,lamina propria T cells
R2 E5-ti-1 T1 objectOf lamina propria,lamina propria T cells
R3 E2-ti-1 T2 subjectOf IL-2,of
R4 E6-ti-1 T2 objectOf T cells,of
R5 E2-ab-1 T3 subjectOf T cells,lamina propria (LP) T cells
R6 E1-ab-1 T3 objectOf lamina propria,lamina propria (LP) T cells
R7 E2-ab-2 T4 subjectOf T cells,LP T cells
R8 E1-ab-2 T4 objectOf LP,LP T cells
R9 E3-ab-2 T5 subjectOf IL-2,activated
R10 E5-ab-2 T5 objectOf CD2,activated
R11 E1-ab-3 T6 subjectOf CD28,enhancement
R12 E2-ab-3 T6 objectOf IL-2,enhancement
R13 E4-ab-4 T7 subjectOf augmentation,mediated
R14 E9-ab-4 T7 objectOf transcriptional activation,mediated
R15 E8-ab-5 T8 subjectOf mononuclear cells,LP mononuclear cells
R16 E7-ab-5 T8 objectOf LP,LP mononuclear cells
R17 E8-ab-5 T9 subjectOf mononuclear cells,in
R18 E5-ab-5 T9 objectOf IL-2,in
R19 E2-ab-6 T10 subjectOf IL-2,activated
R20 E7-ab-6 T10 objectOf CD2,activated
R21 E9-ab-10 T11 subjectOf T cells,LP T cells
R22 E8-ab-10 T11 objectOf LP,LP T cells
R23 E9-ab-10 T12 subjectOf T cells,in
R24 E6-ab-10 T12 objectOf IL-2,in
R25 E11-ab-10 T13 subjectOf peripheral blood T cells,in
R26 E10-ab-10 T13 objectOf compartment,in

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-152 Sentence denotes CD28 costimulation augments IL-2 secretion of activated lamina propria T cells by increasing mRNA stability without enhancing IL-2 gene transactivation.
S2 153-257 Sentence denotes The pathways leading to activation in lamina propria (LP) T cells are different from peripheral T cells.
S3 258-340 Sentence denotes LP T cells exhibit enhanced IL-2 secretion when activated through the CD2 pathway.
S4 341-411 Sentence denotes Coligation of CD28 leads to synergistic enhancement of IL-2 secretion.
S5 412-646 Sentence denotes Previous studies have characterized the CD28 augmentation of TCR-mediated signaling in peripheral blood T cells through transcriptional activation of an IL-2 promoter CD28 response element (CD28RE), along with enhanced mRNA stability.
S6 647-770 Sentence denotes This study characterized molecular events involved in CD28 costimulation of IL-2 production in LP mononuclear cells (LPMC).
S7 771-895 Sentence denotes LPMC exhibited increased IL-2 production in response to CD28 costimulation, compared with cells activated through CD2 alone.
S8 896-1008 Sentence denotes IL-2 secretion was paralleled by increased expression of IL-2 mRNA, resulting from enhanced IL-2 mRNA stability.
S9 1009-1289 Sentence denotes In contrast to transcriptional activation in PBMC, EMSA revealed that CD28 coligation of CD2-activated LPMC does not result in increased binding of trans-factors to the CD28RE, nor did Western blots detect changes in I-kappaBalpha or I-kappaBbeta levels following CD28 coligation.
S10 1290-1411 Sentence denotes Furthermore, CD28 coligation fails to enhance IL-2 promoter-reporter or RE/AP construct expression in CD2-activated LPMC.
S11 1412-1641 Sentence denotes The results reported herein indicate that the molecular mechanisms involved in CD28 cosignaling and regulation of IL-2 secretion in LP T cells are unique to that compartment and differ from those seen in peripheral blood T cells.
S12 1642-1816 Sentence denotes These observations suggest a biological significance for different mechanisms of IL-2 activation in initiation and maintenance of the cytokine repertoire found in the mucosa.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-18 NP denotes CD28 costimulation
C2 191-218 NP denotes lamina propria (LP) T cells
C3 238-256 NP denotes peripheral T cells
C4 258-268 NP denotes LP T cells
C5 341-359 NP denotes Coligation of CD28
C6 396-410 NP denotes IL-2 secretion
C7 499-523 NP denotes peripheral blood T cells
C8 562-609 NP denotes an IL-2 promoter CD28 response element (CD28RE)
C9 742-769 NP denotes LP mononuclear cells (LPMC)
C10 771-775 NP denotes LPMC
C11 827-845 NP denotes CD28 costimulation
C12 896-910 NP denotes IL-2 secretion
C13 1098-1116 NP denotes CD2-activated LPMC
C14 1174-1184 NP denotes the CD28RE
C15 1273-1288 NP denotes CD28 coligation
C16 1303-1318 NP denotes CD28 coligation
C17 1392-1410 NP denotes CD2-activated LPMC
C18 1454-1478 NP denotes the molecular mechanisms
C19 1526-1540 NP denotes IL-2 secretion
C20 1544-1554 NP denotes LP T cells
C21 1602-1607 NP denotes those
C22 1616-1640 NP denotes peripheral blood T cells
R1 C4 C2 coref-ident LP T cells,lamina propria (LP) T cells
R2 C7 C3 coref-ident peripheral blood T cells,peripheral T cells
R3 C10 C9 coref-ident LPMC,LP mononuclear cells (LPMC)
R4 C11 C1 coref-ident CD28 costimulation,CD28 costimulation
R5 C12 C6 coref-ident IL-2 secretion,IL-2 secretion
R6 C14 C8 coref-ident the CD28RE,an IL-2 promoter CD28 response element (CD28RE)
R7 C15 C5 coref-ident CD28 coligation,Coligation of CD28
R8 C16 C15 coref-ident CD28 coligation,CD28 coligation
R9 C17 C13 coref-ident CD2-activated LPMC,CD2-activated LPMC
R10 C19 C12 coref-ident IL-2 secretion,IL-2 secretion
R11 C20 C4 coref-ident LP T cells,LP T cells
R12 C21 C18 coref-pron those,the molecular mechanisms
R13 C22 C7 coref-ident peripheral blood T cells,peripheral blood T cells

metamap-sample

Id Subject Object Predicate Lexical cue
T1 262-269 C0039194 denotes cells
T2 72-79 C0039194 denotes cells
T3 137-152 C0040624 denotes ransactivation.
T4 994-1008 C1257757 denotes RNA stability.
T5 632-646 C1257757 denotes RNA stability.
T6 94-108 C1257757 denotes RNA stability
T7 1545-1547 C1179187 denotes P
T8 743-745 C1179187 denotes P
T9 259-261 C1179187 denotes P
T10 192-206 C1179187 denotes amina propria
T11 57-71 C1179187 denotes amina propria
T12 897-911 C2754073 denotes L-2 secretion
T13 397-411 C2754073 denotes L-2 secretion.
T14 287-301 C2754073 denotes L-2 secretion
T15 29-43 C2754073 denotes L-2 secretion
T16 1137-1146 C0205217 denotes ncreased
T17 930-939 C0205217 denotes ncreased
T18 787-796 C0205217 denotes ncreased
T19 20-28 C0205217 denotes ugments
T20 1329-1336 C2349975 denotes nhance
T21 980-988 C2349975 denotes nhanced
T22 623-631 C2349975 denotes nhanced
T23 382-393 C2349975 denotes nhancement
T24 278-286 C2349975 denotes nhanced
T25 117-126 C2349975 denotes nhancing
T26 127-136 C1705753 denotes L-2 gene
T27 1729-1739 C1879547 denotes ctivation
T28 1397-1406 C1879547 denotes ctivated
T29 1103-1112 C1879547 denotes ctivated
T30 868-877 C1879547 denotes ctivated
T31 307-316 C1879547 denotes ctivated
T32 178-188 C1879547 denotes ctivation
T33 47-56 C1879547 denotes ctivated
T34 83-93 C0442808 denotes ncreasing
T35 1179-1185 C0600508 denotes D28RE,
T36 585-601 C0600508 denotes esponse element
T37 777-786 C0015272 denotes xhibited
T38 270-277 C0015272 denotes xhibit
T39 1025-1051 C0162493 denotes ranscriptional activation
T40 533-559 C0162493 denotes ranscriptional activation
T41 474-477 C0034790 denotes CR-
T42 1649-1661 C0700325 denotes bservations
T43 1195-1208 C0949466 denotes estern blots
T44 1724-1726 C0021764 denotes L-
T45 1061-1065 C0949632 denotes MSA
T46 1337-1341 C0879590 denotes L-2
T47 566-570 C0879590 denotes L-2
T48 1393-1396 C1367475 denotes D2-
T49 1099-1102 C1367475 denotes D2-
T50 886-889 C1367475 denotes D2
T51 329-332 C1367475 denotes D2
T52 1777-1784 C0079189 denotes ytokine
T53 487-496 C0037083 denotes ignaling
T54 659-672 C1880022 denotes haracterized
T55 435-448 C1880022 denotes haracterized
T56 1810-1816 C0026724 denotes ucosa.
T57 333-340 C1704259 denotes athway.
T58 158-166 C1704259 denotes athways
T59 1417-1424 C2825142 denotes esults
T60 1127-1133 C2825142 denotes esult
T61 797-812 C1819447 denotes L-2 production
T62 724-739 C1819447 denotes L-2 production
T63 1480-1488 C1314939 denotes nvolved
T64 690-698 C1314939 denotes nvolved
T65 1710-1720 C0441712 denotes echanisms
T66 1469-1479 C0441712 denotes echanisms
T67 1459-1467 C1521991 denotes olecular
T68 673-682 C1521991 denotes olecular
T69 1700-1708 C1705242 denotes ifferent
T70 224-232 C1705242 denotes ifferent
T71 1342-1350 C0086860 denotes romoter-
T72 571-579 C0086860 denotes romoter
T73 1758-1769 C0024501 denotes aintenance
T74 1575-1586 C1185625 denotes ompartment
T75 1209-1215 C0442726 denotes etect
T76 1320-1325 C0231175 denotes ails
T77 1264-1273 C0332282 denotes ollowing
T78 1123-1126 C1518422 denotes ot
T79 1055-1059 C1321301 denotes BMC,
T80 1425-1433 C0684224 denotes eported
T81 1066-1074 C0443289 denotes evealed
T82 653-658 C2603343 denotes tudy
T83 1326-1328 C1883351 denotes o
T84 1743-1753 C1158830 denotes nitiation
T85 890-895 C0679994 denotes lone.
T86 1513-1541 C3269319 denotes egulation of IL-2 secretion
T87 1662-1669 C1705535 denotes uggest
T88 683-688 C0441471 denotes vents
T89 746-763 C0806987 denotes ononuclear cells
T90 422-429 C0947630 denotes tudies
T91 1560-1566 C1710548 denotes nique
T92 1351-1359 C1709908 denotes eporter
T93 862-867 C0007634 denotes ells
T94 848-856 C1707455 denotes ompared
T95 167-174 C1522538 denotes eading
T96 1216-1223 C0443172 denotes hanges
T97 1797-1802 C0150312 denotes ound
T98 1609-1613 C0205397 denotes een
T99 458-470 C1293122 denotes ugmentation
T100 1147-1154 C1167622 denotes inding
T101 965-974 C0678226 denotes esulting
T102 1379-1389 C0185117 denotes xpression
T103 1158-1163 C2826298 denotes rans-
T104 361-366 C2348269 denotes eads
T105 370-380 C2986495 denotes ynergistic
T106 1683-1695 C0750502 denotes ignificance
T107 1164-1171 C1521761 denotes actors
T108 916-926 C2826345 denotes aralleled
T109 413-421 C0205156 denotes revious
T110 1227-1228 C0221138 denotes -
T111 239-249 C0205100 denotes eripheral
T112 816-824 C0871261 denotes esponse
T113 1369-1378 C2827421 denotes onstruct
T114 478-486 C0127400 denotes ediated
T115 1672-1682 C0205460 denotes iological