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PubMed:10336995 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 582-589 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 582-589 Glycan_Motif denotes mannose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G70323CJ

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 582-589 https://glytoucan.org/Structures/Glycans/G70323CJ denotes mannose

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-185 Sentence denotes Ordered assembly of the asymmetrically branched lipid-linked oligosaccharide in the endoplasmic reticulum is ensured by the substrate specificity of the individual glycosyltransferases.
TextSentencer_T2 186-426 Sentence denotes The assembly of the lipid-linked core oligosaccharide Glc3Man9GlcNAc2, the substrate for N-linked glycosylation of proteins in the endoplasmic reticulum (ER), is catalyzed by different glycosyltransferases located at the membrane of the ER.
TextSentencer_T3 427-621 Sentence denotes We report on the identification and characterization of the ALG12 locus encoding a novel mannosyltransferase responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2.
TextSentencer_T4 622-815 Sentence denotes The biosynthesis of the highly branched oligosaccharide follows an ordered pathway which ensures that only completely assembled oligosaccharide is transferred from the lipid anchor to proteins.
TextSentencer_T5 816-1078 Sentence denotes Using the combination of mutant strains affected in the assembly pathway of lipid-linked oligosaccharides and overexpression of distinct glycosyltransferases, we were able to define the substrate specificities of the transferases that are critical for branching.
TextSentencer_T6 1079-1206 Sentence denotes Our results demonstrate that branched oligosaccharide structures can be specifically recognized by the ER glycosyltransferases.
TextSentencer_T7 1207-1380 Sentence denotes This substrate specificity of the different transferases explains the ordered assembly of the complex structure of lipid-linked Glc3Man9GlcNAc2 in the endoplasmic reticulum.
T1 0-185 Sentence denotes Ordered assembly of the asymmetrically branched lipid-linked oligosaccharide in the endoplasmic reticulum is ensured by the substrate specificity of the individual glycosyltransferases.
T2 186-426 Sentence denotes The assembly of the lipid-linked core oligosaccharide Glc3Man9GlcNAc2, the substrate for N-linked glycosylation of proteins in the endoplasmic reticulum (ER), is catalyzed by different glycosyltransferases located at the membrane of the ER.
T3 427-621 Sentence denotes We report on the identification and characterization of the ALG12 locus encoding a novel mannosyltransferase responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2.
T4 622-815 Sentence denotes The biosynthesis of the highly branched oligosaccharide follows an ordered pathway which ensures that only completely assembled oligosaccharide is transferred from the lipid anchor to proteins.
T5 816-1078 Sentence denotes Using the combination of mutant strains affected in the assembly pathway of lipid-linked oligosaccharides and overexpression of distinct glycosyltransferases, we were able to define the substrate specificities of the transferases that are critical for branching.
T6 1079-1206 Sentence denotes Our results demonstrate that branched oligosaccharide structures can be specifically recognized by the ER glycosyltransferases.
T7 1207-1380 Sentence denotes This substrate specificity of the different transferases explains the ordered assembly of the complex structure of lipid-linked Glc3Man9GlcNAc2 in the endoplasmic reticulum.
T1 0-185 Sentence denotes Ordered assembly of the asymmetrically branched lipid-linked oligosaccharide in the endoplasmic reticulum is ensured by the substrate specificity of the individual glycosyltransferases.
T2 186-426 Sentence denotes The assembly of the lipid-linked core oligosaccharide Glc3Man9GlcNAc2, the substrate for N-linked glycosylation of proteins in the endoplasmic reticulum (ER), is catalyzed by different glycosyltransferases located at the membrane of the ER.
T3 427-621 Sentence denotes We report on the identification and characterization of the ALG12 locus encoding a novel mannosyltransferase responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2.
T4 622-815 Sentence denotes The biosynthesis of the highly branched oligosaccharide follows an ordered pathway which ensures that only completely assembled oligosaccharide is transferred from the lipid anchor to proteins.
T5 816-1078 Sentence denotes Using the combination of mutant strains affected in the assembly pathway of lipid-linked oligosaccharides and overexpression of distinct glycosyltransferases, we were able to define the substrate specificities of the transferases that are critical for branching.
T6 1079-1206 Sentence denotes Our results demonstrate that branched oligosaccharide structures can be specifically recognized by the ER glycosyltransferases.
T7 1207-1380 Sentence denotes This substrate specificity of the different transferases explains the ordered assembly of the complex structure of lipid-linked Glc3Man9GlcNAc2 in the endoplasmic reticulum.

GlycoBiology-GDGDB

Id Subject Object Predicate Lexical cue
_T1 487-492 http://acgg.asia/db/diseases/gdgdb?con_ui=CON00349 denotes ALG12

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 39-47 FMAID:226028 denotes branched
_T2 39-47 FMAID:226027 denotes branched
_T3 48-53 FMAID:67264 denotes lipid
_T4 48-53 FMAID:165448 denotes lipid
_T5 61-76 FMAID:82742 denotes oligosaccharide
_T6 61-76 FMAID:196731 denotes oligosaccharide
_T7 84-95 FMAID:66856 denotes endoplasmic
_T8 84-95 FMAID:165003 denotes endoplasmic
_T9 84-105 FMAID:188464 denotes endoplasmic reticulum
_T10 84-105 FMAID:80351 denotes endoplasmic reticulum
_T11 84-105 FMAID:165142 denotes endoplasmic reticulum
_T12 84-105 FMAID:67438 denotes endoplasmic reticulum
_T13 84-105 FMAID:66897 denotes endoplasmic reticulum
_T14 84-105 FMAID:165026 denotes endoplasmic reticulum
_T15 84-105 FMAID:162308 denotes endoplasmic reticulum
_T16 84-105 FMAID:63842 denotes endoplasmic reticulum
_T17 84-105 FMAID:210679 denotes endoplasmic reticulum
_T18 84-105 FMAID:67434 denotes endoplasmic reticulum
_T19 84-105 FMAID:165141 denotes endoplasmic reticulum
_T20 84-105 FMAID:165027 denotes endoplasmic reticulum
_T21 84-105 FMAID:212510 denotes endoplasmic reticulum
_T22 84-105 FMAID:210694 denotes endoplasmic reticulum
_T23 84-105 FMAID:66898 denotes endoplasmic reticulum
_T24 84-105 FMAID:67429 denotes endoplasmic reticulum
_T25 84-105 FMAID:165250 denotes endoplasmic reticulum
_T26 84-105 FMAID:211269 denotes endoplasmic reticulum
_T27 84-105 FMAID:199093 denotes endoplasmic reticulum
_T28 84-105 FMAID:165144 denotes endoplasmic reticulum
_T29 96-105 FMAID:94520 denotes reticulum
_T30 96-105 FMAID:7646 denotes reticulum
_T31 206-211 FMAID:165448 denotes lipid
_T32 206-211 FMAID:67264 denotes lipid
_T33 224-239 FMAID:196731 denotes oligosaccharide
_T34 224-239 FMAID:82742 denotes oligosaccharide
_T35 301-309 FMAID:165447 denotes proteins
_T36 301-309 FMAID:67257 denotes proteins
_T37 317-328 FMAID:66856 denotes endoplasmic
_T38 317-328 FMAID:165003 denotes endoplasmic
_T39 317-338 FMAID:165141 denotes endoplasmic reticulum
_T40 317-338 FMAID:165144 denotes endoplasmic reticulum
_T41 317-338 FMAID:210694 denotes endoplasmic reticulum
_T42 317-338 FMAID:165027 denotes endoplasmic reticulum
_T43 317-338 FMAID:63842 denotes endoplasmic reticulum
_T44 317-338 FMAID:66898 denotes endoplasmic reticulum
_T45 317-338 FMAID:67434 denotes endoplasmic reticulum
_T46 317-338 FMAID:212510 denotes endoplasmic reticulum
_T47 317-338 FMAID:162308 denotes endoplasmic reticulum
_T48 317-338 FMAID:188464 denotes endoplasmic reticulum
_T49 317-338 FMAID:211269 denotes endoplasmic reticulum
_T50 317-338 FMAID:165142 denotes endoplasmic reticulum
_T51 317-338 FMAID:67438 denotes endoplasmic reticulum
_T52 317-338 FMAID:165026 denotes endoplasmic reticulum
_T53 317-338 FMAID:67429 denotes endoplasmic reticulum
_T54 317-338 FMAID:66897 denotes endoplasmic reticulum
_T55 317-338 FMAID:80351 denotes endoplasmic reticulum
_T56 317-338 FMAID:165250 denotes endoplasmic reticulum
_T57 317-338 FMAID:199093 denotes endoplasmic reticulum
_T58 317-338 FMAID:210679 denotes endoplasmic reticulum
_T59 329-338 FMAID:94520 denotes reticulum
_T60 329-338 FMAID:7646 denotes reticulum
_T61 582-589 FMAID:82801 denotes mannose
_T62 582-589 FMAID:196796 denotes mannose
_T63 653-661 FMAID:226028 denotes branched
_T64 653-661 FMAID:226027 denotes branched
_T65 662-677 FMAID:196731 denotes oligosaccharide
_T66 662-677 FMAID:82742 denotes oligosaccharide
_T67 750-765 FMAID:196731 denotes oligosaccharide
_T68 750-765 FMAID:82742 denotes oligosaccharide
_T69 790-795 FMAID:165448 denotes lipid
_T70 790-795 FMAID:67264 denotes lipid
_T71 806-814 FMAID:67257 denotes proteins
_T72 806-814 FMAID:165447 denotes proteins
_T73 892-897 FMAID:165448 denotes lipid
_T74 892-897 FMAID:67264 denotes lipid
_T75 905-921 FMAID:196731 denotes oligosaccharides
_T76 905-921 FMAID:82742 denotes oligosaccharides
_T77 1068-1077 FMAID:226028 denotes branching
_T78 1068-1077 FMAID:226027 denotes branching
_T79 1108-1116 FMAID:226027 denotes branched
_T80 1108-1116 FMAID:226028 denotes branched
_T81 1117-1132 FMAID:82742 denotes oligosaccharide
_T82 1117-1132 FMAID:196731 denotes oligosaccharide
_T83 1322-1327 FMAID:165448 denotes lipid
_T84 1322-1327 FMAID:67264 denotes lipid
_T85 1358-1369 FMAID:165003 denotes endoplasmic
_T86 1358-1369 FMAID:66856 denotes endoplasmic
_T87 1358-1379 FMAID:210679 denotes endoplasmic reticulum
_T88 1358-1379 FMAID:199093 denotes endoplasmic reticulum
_T89 1358-1379 FMAID:80351 denotes endoplasmic reticulum
_T90 1358-1379 FMAID:188464 denotes endoplasmic reticulum
_T91 1358-1379 FMAID:165250 denotes endoplasmic reticulum
_T92 1358-1379 FMAID:212510 denotes endoplasmic reticulum
_T93 1358-1379 FMAID:162308 denotes endoplasmic reticulum
_T94 1358-1379 FMAID:63842 denotes endoplasmic reticulum
_T95 1358-1379 FMAID:165027 denotes endoplasmic reticulum
_T96 1358-1379 FMAID:66898 denotes endoplasmic reticulum
_T97 1358-1379 FMAID:67429 denotes endoplasmic reticulum
_T98 1358-1379 FMAID:165142 denotes endoplasmic reticulum
_T99 1358-1379 FMAID:210694 denotes endoplasmic reticulum
_T100 1358-1379 FMAID:165144 denotes endoplasmic reticulum
_T101 1358-1379 FMAID:66897 denotes endoplasmic reticulum
_T102 1358-1379 FMAID:165026 denotes endoplasmic reticulum
_T103 1358-1379 FMAID:165141 denotes endoplasmic reticulum
_T104 1358-1379 FMAID:67434 denotes endoplasmic reticulum
_T105 1358-1379 FMAID:67438 denotes endoplasmic reticulum
_T106 1358-1379 FMAID:211269 denotes endoplasmic reticulum
_T107 1370-1379 FMAID:7646 denotes reticulum
_T108 1370-1379 FMAID:94520 denotes reticulum

uniprot-human

Id Subject Object Predicate Lexical cue
T1 340-342 http://www.uniprot.org/uniprot/P03372 denotes ER
T2 423-425 http://www.uniprot.org/uniprot/P03372 denotes ER
T3 1182-1184 http://www.uniprot.org/uniprot/P03372 denotes ER
T4 487-492 http://www.uniprot.org/uniprot/Q9BV10 denotes ALG12
T5 1033-1045 http://www.uniprot.org/uniprot/Q99484 denotes transferases
T6 1251-1263 http://www.uniprot.org/uniprot/Q99484 denotes transferases

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 340-342 http://www.uniprot.org/uniprot/P19785 denotes ER
T2 423-425 http://www.uniprot.org/uniprot/P19785 denotes ER
T3 1182-1184 http://www.uniprot.org/uniprot/P19785 denotes ER
T4 1033-1045 http://www.uniprot.org/uniprot/P38649 denotes transferases
T5 1251-1263 http://www.uniprot.org/uniprot/P38649 denotes transferases

GO-BP

Id Subject Object Predicate Lexical cue
T1 284-297 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T2 284-309 http://purl.obolibrary.org/obo/GO_0006486 denotes glycosylation of proteins
T3 284-328 http://purl.obolibrary.org/obo/GO_0033577 denotes glycosylation of proteins in the endoplasmic
T4 626-638 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis

GO-MF

Id Subject Object Predicate Lexical cue
T1 796-802 http://purl.obolibrary.org/obo/GO_0043495 denotes anchor
T2 796-814 http://purl.obolibrary.org/obo/GO_0043495 denotes anchor to proteins

GO-CC

Id Subject Object Predicate Lexical cue
T1 84-105 http://purl.obolibrary.org/obo/GO_0005783 denotes endoplasmic reticulum
T2 317-338 http://purl.obolibrary.org/obo/GO_0005783 denotes endoplasmic reticulum
T3 1358-1379 http://purl.obolibrary.org/obo/GO_0005783 denotes endoplasmic reticulum
T4 219-223 http://purl.obolibrary.org/obo/GO_0019013 denotes core
T5 340-342 http://purl.obolibrary.org/obo/GO_0005783 denotes ER
T6 423-425 http://purl.obolibrary.org/obo/GO_0005783 denotes ER
T7 1182-1184 http://purl.obolibrary.org/obo/GO_0005783 denotes ER
T8 407-415 http://purl.obolibrary.org/obo/GO_0016020 denotes membrane
T9 407-425 http://purl.obolibrary.org/obo/GO_0005789 denotes membrane of the ER

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 8-16 http://edamontology.org/topic_0196 denotes assembly
T2 48-53 http://edamontology.org/topic_0153 denotes lipid
T3 84-105 http://edamontology.org/topic_0616 denotes endoplasmic reticulum
T4 190-198 http://edamontology.org/topic_0196 denotes assembly
T5 206-211 http://edamontology.org/topic_0153 denotes lipid
T6 301-309 http://edamontology.org/topic_0078 denotes proteins
T7 317-338 http://edamontology.org/topic_0616 denotes endoplasmic reticulum
T8 697-704 http://edamontology.org/topic_0602 denotes pathway
T9 740-749 http://edamontology.org/topic_0196 denotes assembled
T10 790-795 http://edamontology.org/topic_0153 denotes lipid
T11 806-814 http://edamontology.org/topic_0078 denotes proteins
T12 872-880 http://edamontology.org/topic_0196 denotes assembly
T13 881-888 http://edamontology.org/topic_0602 denotes pathway
T14 892-897 http://edamontology.org/topic_0153 denotes lipid
T15 1285-1293 http://edamontology.org/topic_0196 denotes assembly
T16 1322-1327 http://edamontology.org/topic_0153 denotes lipid
T17 1358-1379 http://edamontology.org/topic_0616 denotes endoplasmic reticulum

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 8-16 http://edamontology.org/operation_3433 denotes assembly
T2 190-198 http://edamontology.org/operation_3433 denotes assembly
T3 301-309 http://edamontology.org/data_1467 denotes proteins
T4 301-309 http://edamontology.org/format_1208 denotes proteins
T5 430-436 http://edamontology.org/data_2048 denotes report
T6 493-498 http://edamontology.org/data_2012 denotes locus
T7 697-704 http://edamontology.org/data_2600 denotes pathway
T8 740-749 http://edamontology.org/operation_3433 denotes assembled
T9 806-814 http://edamontology.org/data_1467 denotes proteins
T10 806-814 http://edamontology.org/format_1208 denotes proteins
T11 872-880 http://edamontology.org/operation_3433 denotes assembly
T12 881-888 http://edamontology.org/data_2600 denotes pathway
T13 1091-1102 http://edamontology.org/operation_2246 denotes demonstrate
T14 1133-1143 http://edamontology.org/data_0883 denotes structures
T15 1285-1293 http://edamontology.org/operation_3433 denotes assembly
T16 1309-1318 http://edamontology.org/data_0883 denotes structure

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 96-105 Body_part denotes reticulum http://purl.obolibrary.org/obo/UBERON_0007361
T2 329-338 Body_part denotes reticulum http://purl.obolibrary.org/obo/UBERON_0007361
T3 407-415 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158
T6 1370-1379 Body_part denotes reticulum http://purl.obolibrary.org/obo/UBERON_0007361