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PubMed:10336991 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-64 Sentence denotes Structure of the human gene for lysosomal di-N-acetylchitobiase.
TextSentencer_T2 65-234 Sentence denotes Chitobiase is a lysosomal glycosidase that acts during the ordered degradation of asparagine-linked glycoproteins to cleave the core chitobiose unit at its reducing end.
TextSentencer_T3 235-349 Sentence denotes Human chitobiase is expressed in significant amounts, while bovine chitobiase is produced at extremely low levels.
TextSentencer_T4 350-461 Sentence denotes To begin to understand this species-dependent expression, we determined the gene structure of human chitobiase.
TextSentencer_T5 462-601 Sentence denotes The human chitobiase gene ( CTB S) is approximately 20 kb comprising seven exons varying from 0.1 to 2.3 kb and six introns of 0.3 to 8 kb.
TextSentencer_T6 602-808 Sentence denotes The previously characterized partial bovine chitobiase gene structure is similarly organized including exon and intron sizes and locations, but the human and bovine 5'-flanking regions differ significantly.
TextSentencer_T7 809-950 Sentence denotes 5'-RACE analysis of human chitobiase cDNA revealed only one transcriptional start site 45 bp upstream of the ATG translation initiation site.
TextSentencer_T8 951-1070 Sentence denotes Computer analysis of the human chitobiase gene 5'-flanking region shows characteristics of a typical housekeeping gene.
TextSentencer_T9 1071-1177 Sentence denotes The putative promoter region contains a distal TATA box, and there are several Sp-1 and AP-2 cis elements.
TextSentencer_T10 1178-1302 Sentence denotes In contrast, bovine chitobiase gene 5'-flanking region shows totally different structures and may contain several silencers.
TextSentencer_T11 1303-1398 Sentence denotes A partial art-2 segment which is an artiodactyl Alu -like repetitive sequence, is also present.
TextSentencer_T12 1399-1598 Sentence denotes These evolutionary differences in the 5'-flanking region of the chitobiase genes from human and bovine could account for the widely varied expression levels of the hydrolase within these two species.
T1 0-64 Sentence denotes Structure of the human gene for lysosomal di-N-acetylchitobiase.
T2 65-234 Sentence denotes Chitobiase is a lysosomal glycosidase that acts during the ordered degradation of asparagine-linked glycoproteins to cleave the core chitobiose unit at its reducing end.
T3 235-349 Sentence denotes Human chitobiase is expressed in significant amounts, while bovine chitobiase is produced at extremely low levels.
T4 350-461 Sentence denotes To begin to understand this species-dependent expression, we determined the gene structure of human chitobiase.
T5 462-601 Sentence denotes The human chitobiase gene ( CTB S) is approximately 20 kb comprising seven exons varying from 0.1 to 2.3 kb and six introns of 0.3 to 8 kb.
T6 602-808 Sentence denotes The previously characterized partial bovine chitobiase gene structure is similarly organized including exon and intron sizes and locations, but the human and bovine 5'-flanking regions differ significantly.
T7 809-950 Sentence denotes 5'-RACE analysis of human chitobiase cDNA revealed only one transcriptional start site 45 bp upstream of the ATG translation initiation site.
T8 951-1070 Sentence denotes Computer analysis of the human chitobiase gene 5'-flanking region shows characteristics of a typical housekeeping gene.
T9 1071-1177 Sentence denotes The putative promoter region contains a distal TATA box, and there are several Sp-1 and AP-2 cis elements.
T10 1178-1302 Sentence denotes In contrast, bovine chitobiase gene 5'-flanking region shows totally different structures and may contain several silencers.
T11 1303-1398 Sentence denotes A partial art-2 segment which is an artiodactyl Alu -like repetitive sequence, is also present.
T12 1399-1598 Sentence denotes These evolutionary differences in the 5'-flanking region of the chitobiase genes from human and bovine could account for the widely varied expression levels of the hydrolase within these two species.
T1 0-64 Sentence denotes Structure of the human gene for lysosomal di-N-acetylchitobiase.
T2 65-234 Sentence denotes Chitobiase is a lysosomal glycosidase that acts during the ordered degradation of asparagine-linked glycoproteins to cleave the core chitobiose unit at its reducing end.
T3 235-349 Sentence denotes Human chitobiase is expressed in significant amounts, while bovine chitobiase is produced at extremely low levels.
T4 350-461 Sentence denotes To begin to understand this species-dependent expression, we determined the gene structure of human chitobiase.
T5 462-601 Sentence denotes The human chitobiase gene ( CTB S) is approximately 20 kb comprising seven exons varying from 0.1 to 2.3 kb and six introns of 0.3 to 8 kb.
T6 602-808 Sentence denotes The previously characterized partial bovine chitobiase gene structure is similarly organized including exon and intron sizes and locations, but the human and bovine 5'-flanking regions differ significantly.
T7 809-950 Sentence denotes 5'-RACE analysis of human chitobiase cDNA revealed only one transcriptional start site 45 bp upstream of the ATG translation initiation site.
T8 951-1070 Sentence denotes Computer analysis of the human chitobiase gene 5'-flanking region shows characteristics of a typical housekeeping gene.
T9 1071-1177 Sentence denotes The putative promoter region contains a distal TATA box, and there are several Sp-1 and AP-2 cis elements.
T10 1178-1302 Sentence denotes In contrast, bovine chitobiase gene 5'-flanking region shows totally different structures and may contain several silencers.
T11 1303-1398 Sentence denotes A partial art-2 segment which is an artiodactyl Alu -like repetitive sequence, is also present.
T12 1399-1598 Sentence denotes These evolutionary differences in the 5'-flanking region of the chitobiase genes from human and bovine could account for the widely varied expression levels of the hydrolase within these two species.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 23-27 FMAID:198663 denotes gene
_T2 32-41 FMAID:162299 denotes lysosomal
_T3 32-41 FMAID:63836 denotes lysosomal
_T4 81-90 FMAID:63836 denotes lysosomal
_T5 81-90 FMAID:162299 denotes lysosomal
_T6 147-157 FMAID:82750 denotes asparagine
_T7 147-157 FMAID:196739 denotes asparagine
_T8 165-178 FMAID:62925 denotes glycoproteins
_T9 165-178 FMAID:167256 denotes glycoproteins
_T10 426-430 FMAID:198663 denotes gene
_T11 483-487 FMAID:198663 denotes gene
_T12 537-542 FMAID:198073 denotes exons
_T13 537-542 FMAID:84120 denotes exons
_T14 578-585 FMAID:84121 denotes introns
_T15 578-585 FMAID:198075 denotes introns
_T16 657-661 FMAID:198663 denotes gene
_T17 685-694 FMAID:67498 denotes organized
_T18 685-694 FMAID:166081 denotes organized
_T19 705-709 FMAID:84120 denotes exon
_T20 705-709 FMAID:198073 denotes exon
_T21 714-720 FMAID:84121 denotes intron
_T22 714-720 FMAID:198075 denotes intron
_T23 770-778 FMAID:104341 denotes flanking
_T24 993-997 FMAID:198663 denotes gene
_T25 1001-1009 FMAID:104341 denotes flanking
_T26 1065-1069 FMAID:198663 denotes gene
_T27 1111-1117 FMAID:171166 denotes distal
_T28 1111-1117 FMAID:30327 denotes distal
_T29 1209-1213 FMAID:198663 denotes gene
_T30 1217-1225 FMAID:104341 denotes flanking
_T31 1317-1326 FMAID:172288 denotes 2 segment
_T32 1317-1326 FMAID:71188 denotes 2 segment
_T33 1317-1326 FMAID:166657 denotes 2 segment
_T34 1317-1326 FMAID:62422 denotes 2 segment
_T35 1317-1326 FMAID:71180 denotes 2 segment
_T36 1317-1326 FMAID:172296 denotes 2 segment
_T37 1317-1326 FMAID:256626 denotes 2 segment
_T38 1317-1326 FMAID:172286 denotes 2 segment
_T39 1317-1326 FMAID:256627 denotes 2 segment
_T40 1317-1326 FMAID:71178 denotes 2 segment
_T41 1319-1326 FMAID:256624 denotes segment
_T42 1319-1326 FMAID:256628 denotes segment
_T43 1319-1326 FMAID:256631 denotes segment
_T44 1319-1326 FMAID:256630 denotes segment
_T45 1319-1326 FMAID:256633 denotes segment
_T46 1319-1326 FMAID:256632 denotes segment
_T47 1319-1326 FMAID:99729 denotes segment
_T48 1319-1326 FMAID:11367 denotes segment
_T49 1319-1326 FMAID:256629 denotes segment
_T50 1319-1326 FMAID:256625 denotes segment
_T51 1440-1448 FMAID:104341 denotes flanking
_T52 1474-1479 FMAID:198663 denotes genes

uniprot-human

Id Subject Object Predicate Lexical cue
T1 490-493 http://www.uniprot.org/uniprot/Q01459 denotes CTB
T2 1159-1163 http://www.uniprot.org/uniprot/P05549 denotes AP-2

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 1153-1161 http://www.uniprot.org/uniprot/P05627 denotes 1 and AP
T2 1159-1163 http://www.uniprot.org/uniprot/Q91VX0 denotes AP-2
T3 1164-1167 http://www.uniprot.org/uniprot/Q62225 denotes cis
T4 1313-1316 http://www.uniprot.org/uniprot/Q8K4J0 denotes art
T5 1313-1316 http://www.uniprot.org/uniprot/P56473 denotes art

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 1164-1167 http://purl.bioontology.org/ontology/NCBITAXON/245896 denotes cis

GO-BP

Id Subject Object Predicate Lexical cue
T1 132-143 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T2 132-157 http://purl.obolibrary.org/obo/GO_0006530 denotes degradation of asparagine
T3 869-884 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T4 922-933 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T5 922-944 http://purl.obolibrary.org/obo/GO_0006413 denotes translation initiation
T6 1319-1326 http://purl.obolibrary.org/obo/GO_0035282 denotes segment

GO-CC

Id Subject Object Predicate Lexical cue
T1 32-41 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T2 81-90 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T3 193-197 http://purl.obolibrary.org/obo/GO_0019013 denotes core

UBERON-AE

Id Subject Object Predicate Lexical cue
T1 685-694 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organized

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 685-694 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organized

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 17-22 OrganismTaxon denotes human 9606
T2 235-240 OrganismTaxon denotes Human 9606
T3 295-301 OrganismTaxon denotes bovine 9913
T4 444-449 OrganismTaxon denotes human 9606
T5 466-471 OrganismTaxon denotes human 9606
T6 639-645 OrganismTaxon denotes bovine 9913
T7 750-755 OrganismTaxon denotes human 9606
T8 760-766 OrganismTaxon denotes bovine 9913
T9 829-834 OrganismTaxon denotes human 9606
T10 976-981 OrganismTaxon denotes human 9606
T11 1191-1197 OrganismTaxon denotes bovine 9913
T12 1485-1490 OrganismTaxon denotes human 9606
T13 1495-1501 OrganismTaxon denotes bovine 9913

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1319-1326 Body_part denotes segment http://purl.obolibrary.org/obo/UBERON_0000914