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PubMed:10331564 JSONTXT

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PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 74-93 DiseaseOrPhenotypicFeature denotes chronic hepatitis B 0005366
T2 217-233 DiseaseOrPhenotypicFeature denotes viral infections 0005108
T3 374-393 DiseaseOrPhenotypicFeature denotes chronic hepatitis B 0005366
T4 467-486 DiseaseOrPhenotypicFeature denotes chronic hepatitis B 0005366
T5 748-751 DiseaseOrPhenotypicFeature denotes ALT 0005103|0006097
T7 937-940 DiseaseOrPhenotypicFeature denotes ALT 0005103|0006097
T9 1070-1089 DiseaseOrPhenotypicFeature denotes chronic hepatitis B 0005366

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 14-40 protein denotes Th1 and Th2 type cytokines
T2 55-60 protein denotes HBsAg
T3 65-70 protein denotes HBxAg
T4 108-124 protein denotes cytokine pattern
T5 305-313 protein denotes cytokine
T6 395-412 protein denotes Cytokine profiles
T7 416-450 cell_type denotes peripheral blood mononuclear cells
T8 517-522 protein denotes HBsAg
T9 550-559 protein denotes IFN-gamma
T10 561-565 protein denotes IL-2
T11 567-571 protein denotes IL-4
T12 577-582 protein denotes IL-10
T13 664-673 protein denotes cytokines
T14 693-702 protein denotes IFN-gamma
T15 738-751 protein denotes serum AST/ALT
T16 786-804 protein denotes Th2 type cytokines
T17 832-843 cell_type denotes hepatocytes
T18 850-855 protein denotes HBxAg
T19 910-927 protein denotes cytokine patterns
T20 980-992 protein denotes Th1 cytokine
T21 994-1003 protein denotes IFN-gamma
T22 1008-1013 protein denotes HBsAg
T23 1124-1137 protein denotes Th2 cytokines

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-103 Sentence denotes Expression of Th1 and Th2 type cytokines responding to HBsAg and HBxAg in chronic hepatitis B patients.
S2 104-254 Sentence denotes The cytokine pattern on viral antigen recognition is believed to exert a profound influence on the resolution of viral infections and viral clearance.
S3 255-394 Sentence denotes This study was initiated to investigate whether a cytokine imbalance oriented toward Th2 type response plays a role in chronic hepatitis B.
S4 395-511 Sentence denotes Cytokine profiles of peripheral blood mononuclear cells associated with chronic hepatitis B were analysed by RT-PCR.
S5 512-651 Sentence denotes Upon HBsAg stimulation, expression of IFN-gamma, IL-2, IL-4, and IL-10 was detected in 41%, 8%, 41%, and 50% of the patients, respectively.
S6 652-752 Sentence denotes Among these cytokines, the expression of IFN-gamma was associated with high levels of serum AST/ALT.
S7 753-844 Sentence denotes However, we could not prove that Th2 type cytokines had a protective effect on hepatocytes.
S8 845-948 Sentence denotes Upon HBxAg stimulation, there was no recognizable association of cytokine patterns with AST/ALT levels.
S9 949-1175 Sentence denotes In conclusion, production of a Th1 cytokine, IFN-gamma, by HBsAg-reactive cells was associated with hepatocyte damage in chronic hepatitis B, while no counteracting effect of Th2 cytokines produced by those cells was observed.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 74-102 NP denotes chronic hepatitis B patients
C2 374-393 NP denotes chronic hepatitis B
C3 467-486 NP denotes chronic hepatitis B
C4 517-534 NP denotes HBsAg stimulation
C6 550-559 NP denotes IFN-gamma
C5 550-582 NP denotes IFN-gamma, IL-2, IL-4, and IL-10
C7 624-636 NP denotes the patients
C8 658-673 NP denotes these cytokines
C9 693-702 NP denotes IFN-gamma
C10 786-804 NP denotes Th2 type cytokines
C11 850-867 NP denotes HBxAg stimulation
C12 978-992 NP denotes a Th1 cytokine
C13 994-1003 NP denotes IFN-gamma
C14 1008-1028 NP denotes HBsAg-reactive cells
C15 1070-1089 NP denotes chronic hepatitis B
C16 1124-1137 NP denotes Th2 cytokines
C17 1150-1161 NP denotes those cells
R1 C3 C2 coref-ident chronic hepatitis B,chronic hepatitis B
R2 C7 C1 coref-ident the patients,chronic hepatitis B patients
R3 C8 C5 coref-ident these cytokines,"IFN-gamma, IL-2, IL-4, and IL-10"
R4 C9 C6 coref-ident IFN-gamma,IFN-gamma
R5 C11 C4 coref-ident HBxAg stimulation,HBsAg stimulation
R6 C12 C9 coref-ident a Th1 cytokine,IFN-gamma
R7 C13 C12 coref-appos IFN-gamma,a Th1 cytokine
R8 C15 C3 coref-ident chronic hepatitis B,chronic hepatitis B
R9 C16 C10 coref-ident Th2 cytokines,Th2 type cytokines
R10 C17 C14 coref-ident those cells,HBsAg-reactive cells

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 55-60 protein_molecule denotes HBsAg
T2 65-70 protein_molecule denotes HBxAg
T3 74-102 multi_cell denotes chronic hepatitis B patients
T4 108-124 protein_family_or_group denotes cytokine pattern
T5 128-153 other_name denotes viral antigen recognition
T6 217-233 other_name denotes viral infections
T7 238-253 other_name denotes viral clearance
T8 305-313 protein_family_or_group denotes cytokine
T9 340-357 other_name denotes Th2 type response
T10 374-393 other_name denotes chronic hepatitis B
T11 395-412 protein_family_or_group denotes Cytokine profiles
T12 416-450 cell_type denotes peripheral blood mononuclear cells
T13 467-486 other_name denotes chronic hepatitis B
T14 504-510 other_name denotes RT-PCR
T15 517-522 protein_molecule denotes HBsAg
T16 550-559 protein_molecule denotes IFN-gamma
T17 561-565 protein_molecule denotes IL-2
T18 567-571 protein_molecule denotes IL-4
T19 577-582 protein_molecule denotes IL-10
T20 628-636 multi_cell denotes patients
T21 664-673 protein_family_or_group denotes cytokines
T22 693-702 protein_molecule denotes IFN-gamma
T23 738-751 protein_molecule denotes serum AST/ALT
T24 786-794 protein_family_or_group denotes Th2 type
T25 795-804 protein_family_or_group denotes cytokines
T26 832-843 cell_type denotes hepatocytes
T27 850-855 protein_molecule denotes HBxAg
T28 910-927 protein_family_or_group denotes cytokine patterns
T29 933-947 other_name denotes AST/ALT levels
T30 980-992 protein_family_or_group denotes Th1 cytokine
T31 994-1003 protein_molecule denotes IFN-gamma
T32 1008-1013 protein_molecule denotes HBsAg
T33 1049-1066 other_name denotes hepatocyte damage
T34 1070-1089 other_name denotes chronic hepatitis B
T35 1124-1127 protein_family_or_group denotes Th2
T36 1128-1137 protein_family_or_group denotes cytokines