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performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 440-445 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T2 758-763 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T3 107-116 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T4 331-340 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T5 571-580 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T6 1018-1027 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T7 1261-1270 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary

PubCasesHPO

Id Subject Object Predicate Lexical cue
TI1 107-121 HP:0030005 denotes capillary leak
AB1 331-345 HP:0030005 denotes capillary leak
AB2 571-585 HP:0030005 denotes capillary leak
AB3 999-1004 HP:0001945 denotes fever
AB4 1006-1012 HP:0001903 denotes anemia
AB5 1018-1032 HP:0030005 denotes capillary leak
AB6 1261-1275 HP:0030005 denotes capillary leak

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-170 Sentence denotes Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes.
TextSentencer_T2 171-182 Sentence denotes BACKGROUND:
TextSentencer_T3 183-283 Sentence denotes Sirolimus (formerly rapamycin) is an immunosuppressive agent that interferes with T-cell activation.
TextSentencer_T4 284-493 Sentence denotes After 2 individuals with psoriasis developed a capillary leak syndrome following treatment with oral sirolimus lesional skin cells and activated peripheral blood cells were analyzed for induction of apoptosis.
TextSentencer_T5 494-507 Sentence denotes OBSERVATIONS:
TextSentencer_T6 508-736 Sentence denotes A keratome skin specimen from 1 patient with sirolimus-induced capillary leak syndrome had a 2.3-fold increase in percentage of apoptotic cells (to 48%) compared with an unaffected sirolimus-treated patient with psoriasis (21%).
TextSentencer_T7 737-941 Sentence denotes Activated peripheral blood T cells from patients with psoriasis tended to exhibit greater spontaneous or dexamethasone-induced apoptosis than did normal T cells, particularly in the presence of sirolimus.
TextSentencer_T8 942-954 Sentence denotes CONCLUSIONS:
TextSentencer_T9 955-1042 Sentence denotes Severe adverse effects of sirolimus include fever, anemia, and capillary leak syndrome.
TextSentencer_T10 1043-1209 Sentence denotes These symptoms may be the result of drug-induced apoptosis of lesional leukocytes, especially activated T lymphocytes, and possibly release of inflammatory mediators.
TextSentencer_T11 1210-1421 Sentence denotes Because patients with severe psoriasis may develop capillary leak from various systemic therapies, clinical monitoring is advisable for patients with inflammatory diseases who are treated with immune modulators.
T1 0-170 Sentence denotes Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes.
T2 171-182 Sentence denotes BACKGROUND:
T3 183-283 Sentence denotes Sirolimus (formerly rapamycin) is an immunosuppressive agent that interferes with T-cell activation.
T4 284-493 Sentence denotes After 2 individuals with psoriasis developed a capillary leak syndrome following treatment with oral sirolimus lesional skin cells and activated peripheral blood cells were analyzed for induction of apoptosis.
T5 494-507 Sentence denotes OBSERVATIONS:
T6 508-736 Sentence denotes A keratome skin specimen from 1 patient with sirolimus-induced capillary leak syndrome had a 2.3-fold increase in percentage of apoptotic cells (to 48%) compared with an unaffected sirolimus-treated patient with psoriasis (21%).
T7 737-941 Sentence denotes Activated peripheral blood T cells from patients with psoriasis tended to exhibit greater spontaneous or dexamethasone-induced apoptosis than did normal T cells, particularly in the presence of sirolimus.
T8 942-954 Sentence denotes CONCLUSIONS:
T9 955-1042 Sentence denotes Severe adverse effects of sirolimus include fever, anemia, and capillary leak syndrome.
T10 1043-1209 Sentence denotes These symptoms may be the result of drug-induced apoptosis of lesional leukocytes, especially activated T lymphocytes, and possibly release of inflammatory mediators.
T11 1210-1421 Sentence denotes Because patients with severe psoriasis may develop capillary leak from various systemic therapies, clinical monitoring is advisable for patients with inflammatory diseases who are treated with immune modulators.

PubCasesORDO

Id Subject Object Predicate Lexical cue
TI1 107-130 ORDO:188 denotes capillary leak syndrome
AB1 331-354 ORDO:188 denotes capillary leak syndrome
AB2 571-594 ORDO:188 denotes capillary leak syndrome
AB3 1018-1041 ORDO:188 denotes capillary leak syndrome

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 107-116 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T2 331-340 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T3 571-580 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T4 1018-1027 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T5 1261-1270 http://purl.obolibrary.org/obo/UBERON_0001982 denotes capillary
PD-UBERON-AE-B_T6 440-445 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
PD-UBERON-AE-B_T7 758-763 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 309-318 HP_0003765 denotes psoriasis
T2 331-345 HP_0030005 denotes capillary leak

bc5cdr-valid-experiment

Id Subject Object Predicate Lexical cue
T1 9-17 Disease denotes toxicity
T2 46-55 Chemical denotes sirolimus
T3 66-75 Chemical denotes rapamycin
T4 81-90 Disease denotes psoriasis
T5 107-130 Disease denotes capillary leak syndrome
T6 183-192 Chemical denotes Sirolimus
T7 203-212 Chemical denotes rapamycin
T8 309-318 Disease denotes psoriasis
T9 331-354 Disease denotes capillary leak syndrome
T10 385-394 Chemical denotes sirolimus
T11 553-562 Chemical denotes sirolimus
T12 571-594 Disease denotes capillary leak syndrome
T13 689-698 Chemical denotes sirolimus
T14 720-729 Disease denotes psoriasis
T15 791-800 Disease denotes psoriasis
T16 842-855 Chemical denotes dexamethasone
T17 931-940 Chemical denotes sirolimus
T18 981-990 Chemical denotes sirolimus
T19 999-1004 Disease denotes fever
T20 1006-1012 Disease denotes anemia
T21 1018-1041 Disease denotes capillary leak syndrome
T22 1239-1248 Disease denotes psoriasis
T23 1261-1275 Disease denotes capillary leak
T24 1360-1381 Disease denotes inflammatory diseases