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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 0-5 protein denotes c-Myc
T2 10-13 protein denotes E1A
T3 46-64 cell_type denotes activated NK cells
T4 128-153 cell_type denotes natural killer (NK) cells
T5 159-172 cell_type denotes foreign cells
T6 190-219 cell_type denotes virus-infected or tumor cells
T7 256-264 cell_type denotes NK cells
T8 309-335 cell_type denotes cytotoxic NK cell granules
T9 341-353 protein denotes oncoproteins
T10 354-359 protein denotes c-Myc
T11 364-367 protein denotes E1A
T12 500-513 cell_type denotes foreign cells
T13 515-530 cell_type denotes rat fibroblasts
T14 553-582 cell_type denotes human IL-2 activated NK cells
T15 601-609 cell_type denotes NK cells
T16 705-710 protein denotes c-Myc
T17 714-717 protein denotes E1A
T18 745-776 cell_type denotes oncogene expressing fibroblasts
T19 838-846 cell_type denotes NK cells
T20 867-875 cell_type denotes NK cells
T21 949-997 cell_type denotes oncogene expressing sensitive target fibroblasts
T22 1033-1046 protein denotes wild-type p53
T23 1075-1104 protein denotes anti-apoptotic protein EIB19K
T24 1143-1148 protein denotes c-Myc
T25 1153-1156 protein denotes E1A
T26 1280-1285 protein denotes c-Myc
T27 1290-1293 protein denotes E1A
T28 1309-1320 cell_type denotes fibroblasts
T29 1408-1422 cell_type denotes parental cells
T30 1447-1456 DNA denotes oncogenes
T31 1572-1580 cell_type denotes NK cells
T32 1593-1624 cell_type denotes virus-infected and cancer cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-112 Sentence denotes c-Myc and E1A induced cellular sensitivity to activated NK cells involves cytotoxic granules as death effectors.
S2 113-265 Sentence denotes The contact of natural killer (NK) cells with foreign cells and with certain virus-infected or tumor cells triggers the cytolytic machinery of NK cells.
S3 266-336 Sentence denotes This triggering leads to exocytosis of the cytotoxic NK cell granules.
S4 337-482 Sentence denotes The oncoproteins c-Myc and E1A render cells vulnerable to NK cell mediated cytolysis yet the mechanisms of sensitization are not well understood.
S5 483-718 Sentence denotes In a model where foreign cells (rat fibroblasts) were cocultured with human IL-2 activated NK cells, we observed that NK cells were capable of efficiently killing their targets only if the cells overexpressed the oncogene c-Myc or E1A.
S6 719-998 Sentence denotes Both the parental and the oncogene expressing fibroblasts similarly triggered phosphoinositide hydrolysis in the bound NK cells, demonstrating that NK cells were cytolytically activated in contact with both resistant parental and oncogene expressing sensitive target fibroblasts.
S7 999-1105 Sentence denotes The cell death was independent of wild-type p53 and was not inhibited by an anti-apoptotic protein EIB19K.
S8 1106-1259 Sentence denotes These results provided evidence that c-Myc and E1A activated the NK cell induced cytolysis at a post-triggering stage of NK cell-target cell interaction.
S9 1260-1423 Sentence denotes In consistence, the c-Myc and E1A overexpressing fibroblasts were more sensitive to the cytolytic effects of isolated NK cell-derived granules than parental cells.
S10 1424-1503 Sentence denotes The data indicate that oncogenes activate the cytotoxicity of NK cell granules.
S11 1504-1625 Sentence denotes This mechanism can have a role in directing the cytolytic action of NK cells towards the virus-infected and cancer cells.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-13 NP denotes c-Myc and E1A
C2 128-153 NP denotes natural killer (NK) cells
C3 159-172 NP denotes foreign cells
C4 256-264 NP denotes NK cells
C5 337-367 NP denotes The oncoproteins c-Myc and E1A
C6 486-493 NP denotes a model
C7 494-499 NP denotes where
C8 500-531 NP denotes foreign cells (rat fibroblasts)
C9 601-609 NP denotes NK cells
C10 646-651 NP denotes their
C11 867-875 NP denotes NK cells
C12 1129-1137 NP denotes evidence
C13 1138-1142 NP denotes that
C14 1143-1156 NP denotes c-Myc and E1A
C15 1572-1580 NP denotes NK cells
R1 C4 C2 coref-ident NK cells,natural killer (NK) cells
R2 C5 C1 coref-ident The oncoproteins c-Myc and E1A,c-Myc and E1A
R3 C7 C6 coref-relat where,a model
R4 C8 C3 coref-ident foreign cells (rat fibroblasts),foreign cells
R5 C9 C4 coref-ident NK cells,NK cells
R6 C10 C9 coref-pron their,NK cells
R7 C11 C9 coref-ident NK cells,NK cells
R8 C13 C12 coref-relat that,evidence
R9 C14 C5 coref-ident c-Myc and E1A,The oncoproteins c-Myc and E1A
R10 C15 C11 coref-ident NK cells,NK cells

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-5 protein_molecule denotes c-Myc
T2 10-13 protein_molecule denotes E1A
T3 46-64 cell_type denotes activated NK cells
T4 74-92 cell_component denotes cytotoxic granules
T5 96-111 other_name denotes death effectors
T6 128-153 cell_type denotes natural killer (NK) cells
T7 159-172 cell_type denotes foreign cells
T8 233-252 other_name denotes cytolytic machinery
T9 256-264 cell_type denotes NK cells
T10 309-335 cell_type denotes cytotoxic NK cell granules
T11 341-353 protein_family_or_group denotes oncoproteins
T12 354-359 protein_molecule denotes c-Myc
T13 364-367 protein_molecule denotes E1A
T14 395-421 other_name denotes NK cell mediated cytolysis
T15 444-457 other_name denotes sensitization
T16 500-513 cell_type denotes foreign cells
T17 515-530 cell_type denotes rat fibroblasts
T18 553-558 cell_type denotes human
T19 559-563 protein_molecule denotes IL-2
T20 574-582 cell_type denotes NK cells
T21 601-609 cell_type denotes NK cells
T22 705-710 protein_molecule denotes c-Myc
T23 714-717 protein_molecule denotes E1A
T24 745-776 cell_type denotes oncogene expressing fibroblasts
T25 797-824 other_name denotes phosphoinositide hydrolysis
T26 838-846 cell_type denotes NK cells
T27 867-875 cell_type denotes NK cells
T28 949-997 cell_type denotes oncogene expressing sensitive target fibroblasts
T29 1003-1013 other_name denotes cell death
T30 1033-1046 protein_molecule denotes wild-type p53
T31 1075-1104 protein_molecule denotes anti-apoptotic protein EIB19K
T32 1143-1148 protein_molecule denotes c-Myc
T33 1153-1156 protein_molecule denotes E1A
T34 1171-1196 other_name denotes NK cell induced cytolysis
T35 1227-1258 other_name denotes NK cell-target cell interaction
T36 1280-1285 protein_molecule denotes c-Myc
T37 1290-1293 protein_molecule denotes E1A
T38 1309-1320 cell_type denotes fibroblasts
T39 1378-1402 cell_component denotes NK cell-derived granules
T40 1408-1422 cell_type denotes parental cells
T41 1447-1456 DNA_family_or_group denotes oncogenes
T42 1486-1502 other_artificial_source denotes NK cell granules
T43 1572-1580 cell_type denotes NK cells
T44 1593-1624 cell_type denotes virus-infected and cancer cells

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 208-213 HP_0002664 denotes tumor
T2 1612-1618 HP_0002664 denotes cancer