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PubMed:10235476 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 4-22 protein denotes oestrogen receptor
T2 23-31 DNA denotes codon 10
T3 90-109 cell_type denotes non-malignant cells
T4 192-215 protein denotes intracellular receptors
T5 217-224 protein denotes ERalpha
T6 229-235 protein denotes ERbeta
T7 238-256 protein denotes Oestrogen receptor
T8 303-321 protein denotes N-terminal portion
T9 501-509 DNA denotes codon 10
T10 513-519 DNA denotes exon 1
T11 533-591 cell_line denotes ER-negative and ER-positive human breast cancer cell lines
T12 614-623 DNA denotes blood DNA
T13 678-694 DNA denotes polymorphic site
T14 770-782 DNA denotes DNA sequence
T15 820-845 DNA denotes codon 10 polymorphic site
T16 959-993 cell_type denotes peripheral blood mononuclear cells
T17 1054-1065 DNA denotes ER codon 10
T18 1217-1231 DNA denotes wild-type gene
T19 1285-1306 DNA denotes codon-10-variant type
T20 1356-1377 DNA denotes codon-10-variant type
T21 1528-1539 DNA denotes ER codon 10

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-110 Sentence denotes The oestrogen receptor codon 10 polymorphism detected in breast cancer is also present in non-malignant cells.
S2 111-237 Sentence denotes The effect of oestrogens on oestrogen-receptive organs and cells is mediated via intracellular receptors (ERalpha and ERbeta).
S3 238-479 Sentence denotes Oestrogen receptor gene polymorphisms in the region encoding the N-terminal portion of the protein are reportedly associated with pathological conditions including breast cancer, hypertension, spontaneous abortion and coronary heart disease.
S4 480-695 Sentence denotes A silent mutation in codon 10 of exon 1, detected in ER-negative and ER-positive human breast cancer cell lines, in breast tumors and blood DNA from breast cancer patients, has been recognized as a polymorphic site.
S5 696-1036 Sentence denotes In this study we examined, by denaturing gradient-gel electrophoresis and DNA sequence analysis, the possible presence of a codon 10 polymorphic site in normal oestrogen target organs and cells such as the uterus (myometrium and endometrium), in the placenta and peripheral blood mononuclear cells and in a benign uterus tumour (leiomyoma).
S6 1037-1162 Sentence denotes We have detected ER codon 10 polymorphism in these samples and have compared them to those observed in breast cancer samples.
S7 1163-1307 Sentence denotes All tissues and cells studied were homozygous for the wild-type gene, and were heterozygous as well as homozygous for the codon-10-variant type.
S8 1308-1419 Sentence denotes These results indicate that the presence of the codon-10-variant type is not a characteristic of breast cancer.
S9 1420-1598 Sentence denotes Out current findings suggest that further investigations are warranted to elucidate the possible linkage of ER codon 10 polymorphism to physiological and pathological conditions.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 57-70 NP denotes breast cancer
C2 402-415 NP denotes breast cancer
C3 1054-1078 NP denotes ER codon 10 polymorphism
C4 1122-1127 NP denotes those
C5 1281-1306 NP denotes the codon-10-variant type
C6 1308-1321 NP denotes These results
C7 1352-1377 NP denotes the codon-10-variant type
C8 1405-1418 NP denotes breast cancer
C9 1420-1440 NP denotes Out current findings
C10 1528-1552 NP denotes ER codon 10 polymorphism
R1 C2 C1 coref-ident breast cancer,breast cancer
R2 C4 C3 coref-pron those,ER codon 10 polymorphism
R3 C7 C5 coref-ident the codon-10-variant type,the codon-10-variant type
R4 C8 C2 coref-ident breast cancer,breast cancer
R5 C9 C6 coref-ident Out current findings,These results
R6 C10 C3 coref-ident ER codon 10 polymorphism,ER codon 10 polymorphism

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 4-22 protein_family_or_group denotes oestrogen receptor
T2 23-31 DNA_domain_or_region denotes codon 10
T3 57-70 other_name denotes breast cancer
T4 90-109 cell_type denotes non-malignant cells
T5 125-135 lipid denotes oestrogens
T6 139-148 lipid denotes oestrogen
T7 192-215 protein_family_or_group denotes intracellular receptors
T8 217-224 protein_molecule denotes ERalpha
T9 229-235 protein_molecule denotes ERbeta
T10 238-256 protein_family_or_group denotes Oestrogen receptor
T11 303-321 protein_domain_or_region denotes N-terminal portion
T12 402-415 other_name denotes breast cancer
T13 417-429 other_name denotes hypertension
T14 431-451 other_name denotes spontaneous abortion
T15 456-478 other_name denotes coronary heart disease
T16 482-497 other_name denotes silent mutation
T17 501-509 DNA_domain_or_region denotes codon 10
T18 513-519 DNA_domain_or_region denotes exon 1
T19 596-609 tissue denotes breast tumors
T20 614-623 DNA_family_or_group denotes blood DNA
T21 629-642 other_name denotes breast cancer
T22 678-694 DNA_domain_or_region denotes polymorphic site
T23 726-765 other_name denotes denaturing gradient-gel electrophoresis
T24 770-782 DNA_domain_or_region denotes DNA sequence
T25 820-828 DNA_domain_or_region denotes codon 10
T26 856-879 body_part denotes oestrogen target organs
T27 902-908 body_part denotes uterus
T28 910-920 tissue denotes myometrium
T29 925-936 tissue denotes endometrium
T30 946-954 body_part denotes placenta
T31 959-993 cell_type denotes peripheral blood mononuclear cells
T32 1003-1023 tissue denotes benign uterus tumour
T33 1025-1034 tissue denotes leiomyoma
T34 1054-1065 DNA_domain_or_region denotes ER codon 10
T35 1140-1153 other_name denotes breast cancer
T36 1167-1174 tissue denotes tissues
T37 1217-1231 DNA_domain_or_region denotes wild-type gene
T38 1285-1306 DNA_domain_or_region denotes codon-10-variant type
T39 1356-1377 DNA_domain_or_region denotes codon-10-variant type
T40 1405-1418 other_name denotes breast cancer
T41 1528-1539 DNA_domain_or_region denotes ER codon 10

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 402-415 HP_0003002 denotes breast cancer
T2 402-415 HP_0100013 denotes breast cancer
T3 409-415 HP_0002664 denotes cancer
T4 417-429 HP_0000822 denotes hypertension
T5 431-451 HP_0005268 denotes spontaneous abortion
T6 567-580 HP_0003002 denotes breast cancer
T7 567-580 HP_0100013 denotes breast cancer
T8 574-580 HP_0002664 denotes cancer
T9 596-609 HP_0003002 denotes breast tumors
T10 596-609 HP_0100013 denotes breast tumors
T11 603-609 HP_0002664 denotes tumors
T12 629-642 HP_0003002 denotes breast cancer
T13 629-642 HP_0100013 denotes breast cancer
T14 636-642 HP_0002664 denotes cancer
T15 1017-1023 HP_0002664 denotes tumour
T16 1140-1153 HP_0003002 denotes breast cancer
T17 1140-1153 HP_0100013 denotes breast cancer
T18 1147-1153 HP_0002664 denotes cancer
T19 1405-1418 HP_0003002 denotes breast cancer
T20 1405-1418 HP_0100013 denotes breast cancer
T21 1412-1418 HP_0002664 denotes cancer