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PubMed:10228155 JSONTXT

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PMID_GLOBAL

Id Subject Object Predicate Lexical cue mondo_id
T1 285-311 DiseaseOrPhenotypicFeature denotes adenomatous polyposis coli 0021055
T2 318-323 DiseaseOrPhenotypicFeature denotes tumor 0005070
T3 378-387 DiseaseOrPhenotypicFeature denotes neoplasia 0005070
T4 1590-1595 DiseaseOrPhenotypicFeature denotes tumor 0005070

FSU-PRGE

Id Subject Object Predicate Lexical cue
T1 18-22 protein denotes FWD1
T2 33-42 protein denotes ubiquitin
T3 68-80 protein denotes beta-catenin
T4 82-94 protein denotes beta-catenin
T5 126-134 protein denotes Wingless
T6 135-138 protein denotes Wnt
T7 183-191 protein denotes cadherin
T8 231-243 protein denotes beta-catenin
T9 285-311 protein denotes adenomatous polyposis coli
T10 313-316 protein denotes APC
T11 389-401 protein denotes beta-catenin
T12 430-439 protein denotes ubiquitin
T13 473-485 protein denotes beta-catenin
T14 564-594 protein denotes glycogen synthase kinase-3beta
T15 596-605 protein denotes GSK-3beta
T16 607-611 protein denotes Axin
T17 612-618 protein denotes kinase
T18 646-650 protein denotes FWD1
T19 675-680 protein denotes Slimb
T20 681-689 protein denotes betaTrCP
T21 773-785 protein denotes beta-catenin
T22 787-791 protein denotes Axin
T23 793-802 protein denotes GSK-3beta
T24 807-810 protein denotes APC
T25 868-880 protein denotes beta-catenin
T26 912-916 protein denotes FWD1
T27 918-922 protein denotes FWD1
T28 978-990 protein denotes beta-catenin
T29 1025-1037 protein denotes beta-catenin
T30 1094-1098 protein denotes FWD1
T31 1151-1163 protein denotes beta-catenin
T32 1196-1200 protein denotes Skp1
T33 1201-1207 protein denotes Cullin
T34 1222-1226 protein denotes FWD1
T35 1228-1235 protein denotes SCFFWD1
T36 1237-1253 protein denotes ubiquitin ligase
T37 1277-1289 protein denotes beta-catenin
T38 1314-1318 protein denotes FWD1
T39 1374-1386 protein denotes beta-catenin
T40 1388-1392 protein denotes FWD1
T41 1441-1450 protein denotes ubiquitin
T42 1516-1528 protein denotes beta-catenin
T43 1562-1569 protein denotes SCFFWD1
T44 1646-1658 protein denotes beta-catenin

2015-BEL-Sample

Id Subject Object Predicate Lexical cue
T1 1046-1163 cat(p(HGNC:BTRC)) increases deg(p(HGNC:CTNNB1)) denotes In contrast, a dominant-negative mutant form of FWD1 inhibited the ubiquitination process and stabilized beta-catenin

2015-BEL-Sample-2

Id Subject Object Predicate Lexical cue
BEL:20000066 1046-1163 cat(p(HGNC:BTRC)) increases deg(p(HGNC:CTNNB1)) denotes In contrast, a dominant-negative mutant form of FWD1 inhibited the ubiquitination process and stabilized beta-catenin
BEL:20033576 473-626 complex(p(HGNC:AXIN1),p(HGNC:GSK3B)) directlyIncreases kin(p(HGNC:GSK3B)) denotes beta-catenin ubiquitination is preceded by phosphorylation of its N-terminal region by the glycogen synthase kinase-3beta (GSK-3beta)/Axin kinase complex
BEL:20033604 918-1044 complex(p(HGNC:BTRC),p(HGNC:CTNNB1)) directlyIncreases deg(p(HGNC:CTNNB1)) denotes FWD1 facilitated ubiquitination and promoted degradation of beta-catenin, resulting in reduced cytoplasmic beta-catenin levels
BEL:20034092 812-916 complex(p(HGNC:SKP1),p(HGNC:CUL1),p(HGNC:FBXO5),p(HGNC:BTRC)) directlyIncreases complex(p(HGNC:BTRC),p(HGNC:CTNNB1)) denotes Mutations at the signal-induced phosphorylation site of beta-catenin inhibited its association with FWD1
BEL:20040698 918-1044 p(HGNC:BTRC) increases deg(p(HGNC:CTNNB1)) denotes FWD1 facilitated ubiquitination and promoted degradation of beta-catenin, resulting in reduced cytoplasmic beta-catenin levels
BEL:20041244 812-916 p(HGNC:CTNNB1,pmod(P,S)) increases complex(p(HGNC:BTRC),p(HGNC:CTNNB1)) denotes Mutations at the signal-induced phosphorylation site of beta-catenin inhibited its association with FWD1
BEL:20041246 473-626 p(HGNC:CTNNB1,pmod(P,S)) directlyIncreases deg(p(HGNC:CTNNB1)) denotes beta-catenin ubiquitination is preceded by phosphorylation of its N-terminal region by the glycogen synthase kinase-3beta (GSK-3beta)/Axin kinase complex
BEL:20029422 1046-1163 cat(p(HGNC:BTRC)) increases deg(p(HGNC:CTNNB1)) denotes In contrast, a dominant-negative mutant form of FWD1 inhibited the ubiquitination process and stabilized beta-catenin
BEL:20036696 473-626 kin(p(HGNC:GSK3B)) directlyIncreases p(HGNC:CTNNB1,pmod(P,S)) denotes beta-catenin ubiquitination is preceded by phosphorylation of its N-terminal region by the glycogen synthase kinase-3beta (GSK-3beta)/Axin kinase complex

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 318-323 HP_0002664 denotes tumor
T2 378-387 HP_0002664 denotes neoplasia
T3 1590-1595 HP_0002664 denotes tumor