PubMed:10228026
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-30 | protein | denotes | Thrombin-induced p65 homodimer |
| T2 | 53-68 | DNA | denotes | NF-kappa B site |
| T3 | 106-112 | protein | denotes | ICAM-1 |
| T4 | 128-138 | cell_type | denotes | neutrophil |
| T5 | 189-213 | protein | denotes | proinflammatory mediator |
| T6 | 215-223 | protein | denotes | thrombin |
| T7 | 294-300 | protein | denotes | ICAM-1 |
| T8 | 302-306 | protein | denotes | CD54 |
| T9 | 322-339 | cell_type | denotes | endothelial cells |
| T10 | 356-361 | cell_line | denotes | HUVEC |
| T11 | 367-375 | protein | denotes | thrombin |
| T12 | 426-437 | RNA | denotes | ICAM-1 mRNA |
| T13 | 473-479 | protein | denotes | ICAM-1 |
| T14 | 520-548 | cell_type | denotes | polymorphonuclear leukocytes |
| T15 | 576-593 | cell_type | denotes | endothelial cells |
| T16 | 599-662 | DNA | denotes | ICAM-1 promoter luciferase reporter gene (ICAM-1LUC) constructs |
| T17 | 699-714 | DNA | denotes | NF-kappa B site |
| T18 | 716-726 | DNA | denotes | -533 bases |
| T19 | 732-754 | DNA | denotes | translation start site |
| T20 | 773-781 | protein | denotes | thrombin |
| T21 | 838-853 | DNA | denotes | NF-kappa B site |
| T22 | 855-865 | DNA | denotes | -223 bases |
| T23 | 875-897 | DNA | denotes | translation start site |
| T24 | 927-942 | DNA | denotes | ICAM-1 promoter |
| T25 | 975-990 | DNA | denotes | NF-kappa B site |
| T26 | 1007-1015 | protein | denotes | thrombin |
| T27 | 1030-1040 | protein | denotes | NF-kappa B |
| T28 | 1050-1060 | protein | denotes | luciferase |
| T29 | 1133-1155 | DNA | denotes | plasmid pNF-kappa BLUC |
| T30 | 1182-1207 | DNA | denotes | consensus NF-kappa B site |
| T31 | 1228-1267 | DNA | denotes | adenovirus E1B promoter-luciferase gene |
| T32 | 1284-1292 | protein | denotes | thrombin |
| T33 | 1324-1334 | protein | denotes | NF-kappa B |
| T34 | 1353-1361 | protein | denotes | thrombin |
| T35 | 1412-1420 | protein | denotes | thrombin |
| T36 | 1440-1453 | protein | denotes | NF-kappa Bp65 |
| T37 | 1455-1460 | protein | denotes | Rel A |
| T38 | 1476-1491 | DNA | denotes | NF-kappa B site |
| T39 | 1499-1514 | DNA | denotes | ICAM-1 promoter |
| T40 | 1516-1524 | protein | denotes | Thrombin |
| T41 | 1599-1611 | protein | denotes | NH2 terminus |
| T42 | 1641-1651 | protein | denotes | receptor-1 |
| T43 | 1662-1670 | protein | denotes | thrombin |
| T44 | 1692-1698 | protein | denotes | ICAM-1 |
| T45 | 1736-1744 | protein | denotes | thrombin |
| T46 | 1767-1773 | protein | denotes | ICAM-1 |
| T47 | 1789-1816 | cell_type | denotes | polymorphonuclear leukocyte |
| T48 | 1829-1842 | protein | denotes | NF-kappa Bp65 |
| T49 | 1869-1884 | DNA | denotes | NF-kappa B site |
| T50 | 1888-1903 | DNA | denotes | ICAM-1 promoter |
semrep-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| E1-ti-1 | 0-8 | cui:C0040018 | denotes | Thrombin |
| E2-ti-1 | 9-16 | cui:C0205263 | denotes | induced |
| E3-ti-1 | 17-20 | cui:C0599933 | denotes | p65 |
| E4-ti-1 | 21-30 | entrez:6647 | denotes | homodimer |
| E5-ti-1 | 42-52 | cui:C0522506 | denotes | downstream |
| E6-ti-1 | 53-63 | cui:C0079904 | denotes | NF-kappa B |
| E7-ti-1 | 64-68 | cui:C0205145 | denotes | site |
| E8-ti-1 | 94-105 | cui:C0669365 | denotes | endothelial |
| E9-ti-1 | 106-112 | cui:C0063695 | denotes | ICAM-1 |
| E10-ti-1 | 113-123 | cui:C0185117 | denotes | expression |
| E11-ti-1 | 128-138 | cui:C0027950 | denotes | neutrophil |
| E12-ti-1 | 139-147 | cui:C0001511 | denotes | adhesion |
| T1 | 128-147 | LOCATION_OF | denotes | neutrophil adhesion |
| E1-ab-1 | 169-179 | cui:C0441712 | denotes | mechanisms |
| E2-ab-1 | 215-223 | cui:C0040018 | denotes | thrombin |
| E3-ab-1 | 241-254 | cui:C0442123 | denotes | intravascular |
| E4-ab-1 | 255-266 | cui:C0441509 | denotes | coagulation |
| E5-ab-1 | 278-284 | cui:C0175677 | denotes | injury |
| E6-ab-1 | 294-300 | cui:C0063695 | denotes | ICAM-1 |
| E7-ab-1 | 302-306 | cui:C0063695 | denotes | CD54 |
| E8-ab-1 | 308-318 | cui:C0185117 | denotes | expression |
| E9-ab-1 | 322-339 | cui:C0225336 | denotes | endothelial cells |
| T2 | 286-293 | STIMULATES | denotes | induces |
| E1-ab-2 | 341-352 | cui:C1292856 | denotes | Stimulation |
| E2-ab-2 | 367-375 | cui:C0040018 | denotes | thrombin |
| E3-ab-2 | 388-392 | cui:C1446466 | denotes | dose |
| E4-ab-2 | 398-403 | cui:C0040223 | denotes | time- |
| E5-ab-2 | 413-422 | cui:C0442805 | denotes | increases |
| E6-ab-2 | 426-432 | cui:C0063695 | denotes | ICAM-1 |
| E7-ab-2 | 433-437 | cui:C0035696 | denotes | mRNA |
| E8-ab-2 | 442-454 | cui:C0699040 | denotes | cell surface |
| E9-ab-2 | 455-465 | cui:C0185117 | denotes | expression |
| E10-ab-2 | 473-479 | cui:C0063695 | denotes | ICAM-1 |
| E11-ab-2 | 490-501 | cui:C0669365 | denotes | endothelial |
| E12-ab-2 | 502-512 | cui:C0001516 | denotes | adhesivity |
| E13-ab-2 | 520-548 | cui:C0027950 | denotes | polymorphonuclear leukocytes |
| T3 | 362-366 | USES | denotes | with |
| T4 | 480-489 | AUGMENTS | denotes | dependent |
| E1-ab-3 | 550-559 | cui:C0205374 | denotes | Transient |
| E2-ab-3 | 560-572 | cui:C0040669 | denotes | transfection |
| E3-ab-3 | 576-593 | cui:C0225336 | denotes | endothelial cells |
| E4-ab-3 | 599-605 | cui:C0063695 | denotes | ICAM-1 |
| E5-ab-3 | 615-625 | cui:C0024075 | denotes | luciferase |
| E6-ab-3 | 626-634 | cui:C0335038 | denotes | reporter |
| E7-ab-3 | 606-639 | cui:C0314621 | denotes | promoter luciferase reporter gene |
| E8-ab-3 | 641-650 | cui:C0598077 | denotes | ICAM-1LUC |
| E9-ab-3 | 678-686 | cui:C1442161 | denotes | deletion |
| E10-ab-3 | 690-698 | cui:C0522505 | denotes | upstream |
| E11-ab-3 | 699-709 | cui:C0079904 | denotes | NF-kappa B |
| E12-ab-3 | 710-714 | cui:C0205145 | denotes | site |
| E13-ab-3 | 732-743 | cui:C0040711 | denotes | translation |
| E14-ab-3 | 750-754 | cui:C0205145 | denotes | site |
| E15-ab-3 | 763-769 | cui:C1280500 | denotes | effect |
| E16-ab-3 | 773-781 | cui:C0040018 | denotes | thrombin |
| E17-ab-3 | 782-796 | cui:C0205342 | denotes | responsiveness |
| E18-ab-3 | 806-814 | cui:C0026882 | denotes | mutation |
| E19-ab-3 | 815-823 | cui:C1442161 | denotes | deletion |
| E20-ab-3 | 827-837 | cui:C0522506 | denotes | downstream |
| E21-ab-3 | 838-848 | cui:C0079904 | denotes | NF-kappa B |
| E22-ab-3 | 849-853 | cui:C0205145 | denotes | site |
| E23-ab-3 | 875-886 | cui:C0040711 | denotes | translation |
| E24-ab-3 | 893-897 | cui:C0205145 | denotes | site |
| E25-ab-3 | 927-933 | cui:C0063695 | denotes | ICAM-1 |
| E26-ab-3 | 964-974 | cui:C0522506 | denotes | downstream |
| E27-ab-3 | 975-985 | cui:C0079904 | denotes | NF-kappa B |
| E28-ab-3 | 986-990 | cui:C0205145 | denotes | site |
| E29-ab-3 | 994-1002 | cui:C1511545 | denotes | critical |
| E30-ab-3 | 1007-1015 | cui:C0040018 | denotes | thrombin |
| T5 | 626-639 | PROCESS_OF | denotes | reporter gene |
| T6 | 594-598 | PROCESS_OF | denotes | with |
| E1-ab-4 | 1030-1040 | cui:C0079904 | denotes | NF-kappa B |
| E2-ab-4 | 1050-1060 | cui:C0024075 | denotes | luciferase |
| E3-ab-4 | 1061-1069 | cui:C0439167 | denotes | activity |
| E4-ab-4 | 1080-1093 | cui:C0332232 | denotes | approximately |
| E5-ab-4 | 1096-1100 | cui:C0332462 | denotes | fold |
| E6-ab-4 | 1106-1111 | cui:C0007634 | denotes | cells |
| E7-ab-4 | 1133-1140 | cui:C0032136 | denotes | plasmid |
| E8-ab-4 | 1145-1150 | cui:C0439099 | denotes | kappa |
| E9-ab-4 | 1156-1166 | cui:C0332256 | denotes | containing |
| E10-ab-4 | 1167-1171 | cui:C0205451 | denotes | five |
| E11-ab-4 | 1182-1191 | cui:C0376298 | denotes | consensus |
| E12-ab-4 | 1192-1202 | cui:C0079904 | denotes | NF-kappa B |
| E13-ab-4 | 1203-1207 | cui:C0205145 | denotes | site |
| E14-ab-4 | 1220-1227 | cui:C0547040 | denotes | minimal |
| E15-ab-4 | 1228-1238 | cui:C0001483 | denotes | adenovirus |
| E16-ab-4 | 1239-1242 | entrez:594,6080 | denotes | E1B |
| E17-ab-4 | 1252-1267 | cui:C1334435 | denotes | luciferase gene |
| E18-ab-4 | 1284-1292 | cui:C0040018 | denotes | thrombin |
| E19-ab-4 | 1324-1334 | cui:C0079904 | denotes | NF-kappa B |
| E20-ab-4 | 1339-1348 | cui:C0205224 | denotes | essential |
| E21-ab-4 | 1353-1361 | cui:C0040018 | denotes | thrombin |
| E22-ab-4 | 1362-1370 | cui:C0871261 | denotes | response |
| T7 | 1203-1207 | LOCATION_OF | denotes | site |
| T8 | 1228-1242 | PART_OF | denotes | adenovirus E1B |
| T9 | 1310-1320 | STIMULATES | denotes | activation |
| E1-ab-5 | 1372-1375 | cui:C0017243 | denotes | Gel |
| E2-ab-5 | 1387-1393 | cui:C1510438 | denotes | assays |
| E3-ab-5 | 1412-1420 | cui:C0040018 | denotes | thrombin |
| E4-ab-5 | 1443-1448 | cui:C0439099 | denotes | kappa |
| E5-ab-5 | 1455-1458 | cui:C0751998 | denotes | Rel |
| E6-ab-5 | 1465-1475 | cui:C0522506 | denotes | downstream |
| E7-ab-5 | 1476-1486 | cui:C0079904 | denotes | NF-kappa B |
| E8-ab-5 | 1487-1491 | cui:C0205145 | denotes | site |
| E9-ab-5 | 1499-1505 | cui:C0063695 | denotes | ICAM-1 |
| E1-ab-6 | 1516-1524 | cui:C0040018 | denotes | Thrombin |
| E2-ab-6 | 1525-1544 | cui:C1514758 | denotes | receptor activation |
| E3-ab-6 | 1545-1552 | cui:C0030956 | denotes | peptide |
| E4-ab-6 | 1559-1569 | cui:C0002520 | denotes | amino-acid |
| E5-ab-6 | 1570-1577 | cui:C0030956 | denotes | peptide |
| E6-ab-6 | 1595-1598 | cui:C0205314 | denotes | new |
| E7-ab-6 | 1599-1602 | cui:C0025033 | denotes | NH2 |
| E8-ab-6 | 1631-1640 | cui:C1515877 | denotes | activated |
| E9-ab-6 | 1641-1649 | cui:C0597357 | denotes | receptor |
| E10-ab-6 | 1662-1672 | cui:C0040018 | denotes | thrombin's |
| E11-ab-6 | 1683-1691 | cui:C0205263 | denotes | inducing |
| E12-ab-6 | 1692-1698 | cui:C0063695 | denotes | ICAM-1 |
| E13-ab-6 | 1699-1709 | cui:C0185117 | denotes | expression |
| T10 | 1631-1640 | STIMULATES | denotes | activated |
| E1-ab-7 | 1717-1721 | cui:C1511726 | denotes | data |
| E2-ab-7 | 1736-1744 | cui:C0040018 | denotes | thrombin |
| E3-ab-7 | 1755-1766 | cui:C0669365 | denotes | endothelial |
| E4-ab-7 | 1767-1773 | cui:C0063695 | denotes | ICAM-1 |
| E5-ab-7 | 1774-1784 | cui:C0185117 | denotes | expression |
| E6-ab-7 | 1789-1816 | cui:C0027950 | denotes | polymorphonuclear leukocyte |
| E7-ab-7 | 1817-1825 | cui:C0001511 | denotes | adhesion |
| E8-ab-7 | 1832-1837 | cui:C0439099 | denotes | kappa |
| E9-ab-7 | 1858-1868 | cui:C0522506 | denotes | downstream |
| E10-ab-7 | 1869-1879 | cui:C0079904 | denotes | NF-kappa B |
| E11-ab-7 | 1880-1884 | cui:C0205145 | denotes | site |
| E12-ab-7 | 1888-1894 | cui:C0063695 | denotes | ICAM-1 |
| E13-ab-7 | 1926-1935 | cui:C1515877 | denotes | activated |
| E14-ab-7 | 1936-1957 | cui:C1514758 | denotes | receptor-1 activation |
| T11 | 1745-1754 | STIMULATES | denotes | activates |
| T12 | 1789-1825 | LOCATION_OF | denotes | polymorphonuclear leukocyte adhesion |
| R1 | E11-ti-1 | T1 | subjectOf | neutrophil,neutrophil adhesion |
| R2 | E12-ti-1 | T1 | objectOf | adhesion,neutrophil adhesion |
| R3 | E2-ab-1 | T2 | subjectOf | thrombin,induces |
| R4 | E6-ab-1 | T2 | objectOf | ICAM-1,induces |
| R5 | E1-ab-2 | T3 | subjectOf | Stimulation,with |
| R6 | E2-ab-2 | T3 | objectOf | thrombin,with |
| R7 | E7-ab-2 | T4 | subjectOf | mRNA,dependent |
| R8 | E13-ab-2 | T4 | objectOf | polymorphonuclear leukocytes,dependent |
| R9 | E7-ab-3 | T5 | subjectOf | promoter luciferase reporter gene,reporter gene |
| R10 | E6-ab-3 | T5 | objectOf | reporter,reporter gene |
| R11 | E7-ab-3 | T6 | subjectOf | promoter luciferase reporter gene,with |
| R12 | E2-ab-3 | T6 | objectOf | transfection,with |
| R13 | E6-ab-4 | T7 | subjectOf | cells,site |
| R14 | E12-ab-4 | T7 | objectOf | NF-kappa B,site |
| R15 | E16-ab-4 | T8 | subjectOf | E1B,adenovirus E1B |
| R16 | E15-ab-4 | T8 | objectOf | adenovirus,adenovirus E1B |
| R17 | E18-ab-4 | T9 | subjectOf | thrombin,activation |
| R18 | E19-ab-4 | T9 | objectOf | NF-kappa B,activation |
| R19 | E4-ab-6 | T10 | subjectOf | amino-acid,activated |
| R20 | E12-ab-6 | T10 | objectOf | ICAM-1,activated |
| R21 | E2-ab-7 | T11 | subjectOf | thrombin,activates |
| R22 | E4-ab-7 | T11 | objectOf | ICAM-1,activates |
| R23 | E6-ab-7 | T12 | subjectOf | polymorphonuclear leukocyte,polymorphonuclear leukocyte adhesion |
| R24 | E7-ab-7 | T12 | objectOf | adhesion,polymorphonuclear leukocyte adhesion |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-148 | Sentence | denotes | Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion. |
| S2 | 149-340 | Sentence | denotes | We investigated the mechanisms by which proinflammatory mediator, thrombin, released during intravascular coagulation and tissue injury, induces ICAM-1 (CD54) expression in endothelial cells. |
| S3 | 341-549 | Sentence | denotes | Stimulation of HUVEC with thrombin resulted in dose- and time-dependent increases in ICAM-1 mRNA and cell surface expression and in ICAM-1-dependent endothelial adhesivity toward polymorphonuclear leukocytes. |
| S4 | 550-1029 | Sentence | denotes | Transient transfection of endothelial cells with ICAM-1 promoter luciferase reporter gene (ICAM-1LUC) constructs indicated that deletion of upstream NF-kappa B site (-533 bases from translation start site) had no effect on thrombin responsiveness, whereas mutation/deletion of downstream NF-kappa B site (-223 bases from the translation start site) prevented the activation of ICAM-1 promoter, indicating that the downstream NF-kappa B site is critical for thrombin inducibility. |
| S5 | 1030-1371 | Sentence | denotes | NF-kappa B-directed luciferase activity increased approximately 3-fold when cells transfected with the plasmid pNF-kappa BLUC containing five copies of consensus NF-kappa B site linked to a minimal adenovirus E1B promoter-luciferase gene were exposed to thrombin, indicating that activation of NF-kappa B was essential for thrombin response. |
| S6 | 1372-1515 | Sentence | denotes | Gel supershift assays demonstrated that thrombin induced binding of NF-kappa Bp65 (Rel A) to downstream NF-kappa B site of the ICAM-1 promoter. |
| S7 | 1516-1710 | Sentence | denotes | Thrombin receptor activation peptide, a 14-amino-acid peptide representing the new NH2 terminus of proteolytically activated receptor-1, mimicked thrombin's action in inducing ICAM-1 expression. |
| S8 | 1711-1958 | Sentence | denotes | These data indicate that thrombin activates endothelial ICAM-1 expression and polymorphonuclear leukocyte adhesion by NF-kappa Bp65 binding to the downstream NF-kappa B site of ICAM-1 promoter after proteolytically activated receptor-1 activation. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 94-123 | NP | denotes | endothelial ICAM-1 expression |
| C2 | 165-179 | NP | denotes | the mechanisms |
| C3 | 183-188 | NP | denotes | which |
| C4 | 189-213 | NP | denotes | proinflammatory mediator |
| C5 | 215-223 | NP | denotes | thrombin |
| C6 | 322-339 | NP | denotes | endothelial cells |
| C7 | 367-375 | NP | denotes | thrombin |
| C8 | 576-593 | NP | denotes | endothelial cells |
| C9 | 827-898 | NP | denotes | downstream NF-kappa B site (-223 bases from the translation start site) |
| C10 | 927-942 | NP | denotes | ICAM-1 promoter |
| C11 | 960-990 | NP | denotes | the downstream NF-kappa B site |
| C12 | 1284-1292 | NP | denotes | thrombin |
| C13 | 1412-1420 | NP | denotes | thrombin |
| C15 | 1495-1514 | NP | denotes | the ICAM-1 promoter |
| C14 | 1465-1514 | NP | denotes | downstream NF-kappa B site of the ICAM-1 promoter |
| C16 | 1516-1552 | NP | denotes | Thrombin receptor activation peptide |
| C17 | 1554-1651 | NP | denotes | a 14-amino-acid peptide representing the new NH2 terminus of proteolytically activated receptor-1 |
| C18 | 1736-1744 | NP | denotes | thrombin |
| C19 | 1755-1784 | NP | denotes | endothelial ICAM-1 expression |
| C21 | 1888-1903 | NP | denotes | ICAM-1 promoter |
| C20 | 1854-1903 | NP | denotes | the downstream NF-kappa B site of ICAM-1 promoter |
| R1 | C3 | C2 | coref-relat | which,the mechanisms |
| R2 | C5 | C4 | coref-appos | thrombin,proinflammatory mediator |
| R3 | C7 | C4 | coref-ident | thrombin,proinflammatory mediator |
| R4 | C8 | C6 | coref-ident | endothelial cells,endothelial cells |
| R5 | C11 | C9 | coref-ident | the downstream NF-kappa B site,downstream NF-kappa B site (-223 bases from the translation start site) |
| R6 | C12 | C7 | coref-ident | thrombin,thrombin |
| R7 | C13 | C12 | coref-ident | thrombin,thrombin |
| R8 | C15 | C10 | coref-ident | the ICAM-1 promoter,ICAM-1 promoter |
| R9 | C17 | C16 | coref-appos | a 14-amino-acid peptide representing the new NH2 terminus of proteolytically activated receptor-1,Thrombin receptor activation peptide |
| R10 | C18 | C13 | coref-ident | thrombin,thrombin |
| R11 | C19 | C1 | coref-ident | endothelial ICAM-1 expression,endothelial ICAM-1 expression |
| R12 | C21 | C15 | coref-ident | ICAM-1 promoter,the ICAM-1 promoter |
| R13 | C20 | C14 | coref-ident | the downstream NF-kappa B site of ICAM-1 promoter,downstream NF-kappa B site of the ICAM-1 promoter |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-8 | protein_molecule | denotes | Thrombin |
| T2 | 17-20 | protein_molecule | denotes | p65 |
| T3 | 53-63 | protein_complex | denotes | NF-kappa B |
| T4 | 94-105 | other_name | denotes | endothelial |
| T5 | 106-112 | protein_molecule | denotes | ICAM-1 |
| T6 | 128-138 | cell_type | denotes | neutrophil |
| T7 | 189-213 | protein_family_or_group | denotes | proinflammatory mediator |
| T8 | 215-223 | protein_molecule | denotes | thrombin |
| T9 | 241-266 | other_name | denotes | intravascular coagulation |
| T10 | 271-284 | other_name | denotes | tissue injury |
| T11 | 294-300 | protein_molecule | denotes | ICAM-1 |
| T12 | 302-306 | protein_molecule | denotes | CD54 |
| T13 | 322-339 | cell_type | denotes | endothelial cells |
| T14 | 356-361 | cell_line | denotes | HUVEC |
| T15 | 367-375 | protein_molecule | denotes | thrombin |
| T16 | 426-437 | RNA_molecule | denotes | ICAM-1 mRNA |
| T17 | 442-465 | other_name | denotes | cell surface expression |
| T18 | 473-479 | protein_molecule | denotes | ICAM-1 |
| T19 | 520-548 | cell_type | denotes | polymorphonuclear leukocytes |
| T20 | 576-593 | cell_type | denotes | endothelial cells |
| T21 | 599-605 | protein_molecule | denotes | ICAM-1 |
| T22 | 699-709 | protein_complex | denotes | NF-kappa B |
| T23 | 716-726 | DNA_domain_or_region | denotes | -533 bases |
| T24 | 732-754 | DNA_domain_or_region | denotes | translation start site |
| T25 | 773-781 | protein_molecule | denotes | thrombin |
| T26 | 838-848 | protein_complex | denotes | NF-kappa B |
| T27 | 855-865 | DNA_domain_or_region | denotes | -223 bases |
| T28 | 875-897 | DNA_domain_or_region | denotes | translation start site |
| T29 | 927-933 | protein_molecule | denotes | ICAM-1 |
| T30 | 975-985 | protein_complex | denotes | NF-kappa B |
| T31 | 1007-1015 | protein_molecule | denotes | thrombin |
| T32 | 1030-1040 | protein_molecule | denotes | NF-kappa B |
| T33 | 1050-1060 | protein_molecule | denotes | luciferase |
| T34 | 1133-1155 | DNA_molecule | denotes | plasmid pNF-kappa BLUC |
| T35 | 1182-1191 | DNA_domain_or_region | denotes | consensus |
| T36 | 1192-1202 | protein_complex | denotes | NF-kappa B |
| T37 | 1228-1267 | DNA_domain_or_region | denotes | adenovirus E1B promoter-luciferase gene |
| T38 | 1284-1292 | protein_molecule | denotes | thrombin |
| T39 | 1324-1334 | protein_complex | denotes | NF-kappa B |
| T40 | 1353-1361 | protein_molecule | denotes | thrombin |
| T41 | 1412-1420 | protein_molecule | denotes | thrombin |
| T42 | 1440-1453 | protein_subunit | denotes | NF-kappa Bp65 |
| T43 | 1455-1460 | protein_subunit | denotes | Rel A |
| T44 | 1476-1486 | protein_complex | denotes | NF-kappa B |
| T45 | 1499-1505 | protein_molecule | denotes | ICAM-1 |
| T46 | 1516-1524 | protein_molecule | denotes | Thrombin |
| T47 | 1556-1577 | peptide | denotes | 14-amino-acid peptide |
| T48 | 1599-1611 | protein_domain_or_region | denotes | NH2 terminus |
| T49 | 1641-1651 | protein_molecule | denotes | receptor-1 |
| T50 | 1662-1670 | protein_molecule | denotes | thrombin |
| T51 | 1692-1698 | protein_molecule | denotes | ICAM-1 |
| T52 | 1736-1744 | protein_molecule | denotes | thrombin |
| T53 | 1767-1773 | protein_molecule | denotes | ICAM-1 |
| T54 | 1789-1816 | cell_type | denotes | polymorphonuclear leukocyte |
| T55 | 1829-1842 | protein_subunit | denotes | NF-kappa Bp65 |
| T56 | 1869-1879 | protein_complex | denotes | NF-kappa B |
| T57 | 1888-1894 | protein_molecule | denotes | ICAM-1 |
| T58 | 1936-1957 | other_name | denotes | receptor-1 activation |
metamap-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1737-1745 | C0040018 | denotes | hrombin |
| T2 | 1517-1525 | C0040018 | denotes | hrombin |
| T3 | 1663-1673 | C0040018 | denotes | hrombin's |
| T4 | 1413-1421 | C0040018 | denotes | hrombin |
| T5 | 368-375 | C0040018 | denotes | hrombin |
| T6 | 216-224 | C0040018 | denotes | hrombin, |
| T7 | 1-9 | C0040018 | denotes | hrombin- |
| T8 | 1790-1817 | C0027950 | denotes | olymorphonuclear leukocyte |
| T9 | 521-549 | C0027950 | denotes | olymorphonuclear leukocytes. |
| T10 | 129-139 | C0027950 | denotes | eutrophil |
| T11 | 1693-1699 | C0063695 | denotes | CAM-1 |
| T12 | 1500-1506 | C0063695 | denotes | CAM-1 |
| T13 | 928-934 | C0063695 | denotes | CAM-1 |
| T14 | 295-300 | C0063695 | denotes | CAM-1 |
| T15 | 107-113 | C0063695 | denotes | CAM-1 |
| T16 | 1818-1826 | C0001511 | denotes | dhesion |
| T17 | 140-148 | C0001511 | denotes | dhesion. |
| T18 | 1756-1767 | C0014257 | denotes | ndothelial |
| T19 | 491-502 | C0014257 | denotes | ndothelial |
| T20 | 95-106 | C0014257 | denotes | ndothelial |
| T21 | 86-94 | C0086597 | denotes | ediates |
| T22 | 1775-1785 | C0185117 | denotes | xpression |
| T23 | 456-466 | C0185117 | denotes | xpression |
| T24 | 309-319 | C0185117 | denotes | xpression |
| T25 | 114-124 | C0185117 | denotes | xpression |
| T26 | 1684-1691 | C0205263 | denotes | nducing |
| T27 | 1422-1429 | C0205263 | denotes | nduced |
| T28 | 287-294 | C0205263 | denotes | nduces |
| T29 | 10-17 | C0205263 | denotes | nduced |
| T30 | 1896-1904 | C0086860 | denotes | romoter |
| T31 | 1507-1515 | C0086860 | denotes | romoter. |
| T32 | 1244-1252 | C0086860 | denotes | romoter- |
| T33 | 77-85 | C0086860 | denotes | romoter |
| T34 | 1693-1699 | C1334074 | denotes | CAM-1 |
| T35 | 1500-1506 | C1334074 | denotes | CAM-1 |
| T36 | 928-934 | C1334074 | denotes | CAM-1 |
| T37 | 295-300 | C1334074 | denotes | CAM-1 |
| T38 | 107-113 | C1334074 | denotes | CAM-1 |
| T39 | 1881-1885 | C0205145 | denotes | ite |
| T40 | 1488-1492 | C0205145 | denotes | ite |
| T41 | 1204-1208 | C0205145 | denotes | ite |
| T42 | 65-69 | C0205145 | denotes | ite |
| T43 | 1844-1851 | C1167622 | denotes | inding |
| T44 | 1430-1437 | C1167622 | denotes | inding |
| T45 | 32-39 | C1167622 | denotes | inding |
| T46 | 1859-1869 | C0522506 | denotes | ownstream |
| T47 | 1466-1476 | C0522506 | denotes | ownstream |
| T48 | 43-53 | C0522506 | denotes | ownstream |
| T49 | 1870-1880 | C0079904 | denotes | F-kappa B |
| T50 | 1477-1487 | C0079904 | denotes | F-kappa B |
| T51 | 679-687 | C1511760 | denotes | eletion |
| T52 | 807-824 | C1511760 | denotes | utation/deletion |
| T53 | 1253-1263 | C0024075 | denotes | uciferase |
| T54 | 616-626 | C0024075 | denotes | uciferase |
| T55 | 1517-1534 | C0668084 | denotes | hrombin receptor |
| T56 | 577-594 | C0225336 | denotes | ndothelial cells |
| T57 | 323-340 | C0225336 | denotes | ndothelial cells. |
| T58 | 1600-1603 | C0025033 | denotes | H2 |
| T59 | 256-267 | C0005778 | denotes | oagulation |
| T60 | 1229-1239 | C1552907 | denotes | denovirus |
| T61 | 1373-1376 | C0017243 | denotes | el |
| T62 | 1183-1192 | C0376298 | denotes | onsensus |
| T63 | 1927-1935 | C1879547 | denotes | ctivated |
| T64 | 1632-1641 | C1879547 | denotes | ctivated |
| T65 | 1535-1544 | C1879547 | denotes | ctivation |
| T66 | 914-924 | C1879547 | denotes | ctivation |
| T67 | 561-573 | C0040669 | denotes | ransfection |
| T68 | 434-438 | C0035696 | denotes | RNA |
| T69 | 1042-1050 | C0449738 | denotes | irected |
| T70 | 1017-1029 | C0669372 | denotes | nducibility. |
| T71 | 1833-1838 | C0439099 | denotes | appa |
| T72 | 1444-1449 | C0439099 | denotes | appa |
| T73 | 1146-1151 | C0439099 | denotes | appa |
| T74 | 1134-1141 | C0032136 | denotes | lasmid |
| T75 | 503-513 | C0001516 | denotes | dhesivity |
| T76 | 1526-1544 | C1514758 | denotes | eceptor activation |
| T77 | 1388-1394 | C0005507 | denotes | ssays |
| T78 | 1560-1570 | C0002520 | denotes | mino-acid |
| T79 | 399-403 | C0040223 | denotes | ime- |
| T80 | 1107-1112 | C0007634 | denotes | ells |
| T81 | 1718-1722 | C1511726 | denotes | ata |
| T82 | 1071-1080 | C0205217 | denotes | ncreased |
| T83 | 664-673 | C1444656 | denotes | ndicated |
| T84 | 153-165 | C1292732 | denotes | nvestigated |
| T85 | 1746-1755 | C1515877 | denotes | ctivates |
| T86 | 653-663 | C2827421 | denotes | onstructs |
| T87 | 900-909 | C0309872 | denotes | revented |
| T88 | 1579-1591 | C1882932 | denotes | epresenting |
| T89 | 1311-1335 | C1749855 | denotes | ctivation of NF-kappa B |
| T90 | 443-454 | C0699040 | denotes | ell surface |
| T91 | 1274-1284 | C0332157 | denotes | xposed to |
| T92 | 279-285 | C3263722 | denotes | njury, |
| T93 | 1097-1101 | C0332462 | denotes | old |
| T94 | 1051-1069 | C1151115 | denotes | uciferase activity |
| T95 | 761-770 | C1301751 | denotes | o effect |
| T96 | 389-393 | C0178602 | denotes | ose- |
| T97 | 342-353 | C1292856 | denotes | timulation |
| T98 | 995-1003 | C1511545 | denotes | ritical |
| T99 | 1340-1349 | C0205224 | denotes | ssential |
| T100 | 242-255 | C0442123 | denotes | ntravascular |
| T101 | 226-234 | C0391871 | denotes | eleased |
| T102 | 377-385 | C1274040 | denotes | esulted |
| T103 | 170-180 | C0441712 | denotes | echanisms |
| T104 | 467-470 | C1515981 | denotes | nd |
| T105 | 414-423 | C0442805 | denotes | ncreases |
| T106 | 1221-1227 | C1524031 | denotes | inimal |
| T107 | 1157-1167 | C2700400 | denotes | ontaining |
| T108 | 1173-1179 | C1948062 | denotes | opies |
| T109 | 1168-1172 | C0205451 | denotes | ive |
| T110 | 272-278 | C0040300 | denotes | issue |
| T111 | 642-646 | C0598077 | denotes | CAM- |
| T112 | 1081-1094 | C0332232 | denotes | pproximately |
| T113 | 627-635 | C1709908 | denotes | eporter |
| T114 | 1363-1371 | C0871261 | denotes | esponse. |
| T115 | 551-560 | C0205374 | denotes | ransient |
| T116 | 206-214 | C1363844 | denotes | ediator, |
| T117 | 691-699 | C0522505 | denotes | pstream |
| T118 | 1596-1599 | C0205314 | denotes | ew |
| T119 | 1642-1650 | C0597357 | denotes | eceptor- |
| T120 | 783-797 | C0205342 | denotes | esponsiveness, |