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sentences

Id Subject Object Predicate Lexical cue
T1 0-134 Sentence denotes Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells.
T2 135-267 Sentence denotes Smad6 and Smad7 prevent ligand-induced activation of signal-transducing Smad proteins in the transforming growth factor-beta family.
T3 268-468 Sentence denotes Here we demonstrate that both Smad6 and Smad7 are human bone morphogenetic protein-2 (hBMP-2)-inducible antagonists of hBMP-2-induced growth arrest and apoptosis in mouse B cell hybridoma HS-72 cells.
T4 469-597 Sentence denotes Moreover, we confirmed that the ectopic expressions of Smad6 and Smad7 inhibited the hBMP-2-induced Smad1/Smad5 phosphorylation.
T5 598-733 Sentence denotes We previously reported that Smad7 is an activin A-inducible antagonist of activin A-induced growth arrest and apoptosis in HS-72 cells.
T6 734-909 Sentence denotes Interestingly, although mRNA expression of Smad6 was induced by activin A in HS-72 cells, Smad6 showed no antagonistic effect on activin A-induced growth arrest and apoptosis.
T7 910-1051 Sentence denotes Moreover, we found that the ectopic expression of Smad7, but not Smad6, inhibited the activin A-induced Smad2 phosphorylation in HS-72 cells.
T8 1052-1199 Sentence denotes Thus, Smad6 and Smad7 exhibit differential inhibitory effects in bone morphogenetic protein-2- and activin A-mediated signaling in B lineage cells.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 46-50 http://purl.obolibrary.org/obo/MAT_0000299 denotes bone
T2 324-328 http://purl.obolibrary.org/obo/MAT_0000299 denotes bone
T3 1117-1121 http://purl.obolibrary.org/obo/MAT_0000299 denotes bone

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 27-32 protein denotes Smad6
T2 37-42 protein denotes Smad7
T3 126-133 cell_type denotes B cells
T4 135-140 protein denotes Smad6
T5 145-150 protein denotes Smad7
T6 188-220 protein denotes signal-transducing Smad proteins
T7 228-266 protein denotes transforming growth factor-beta family
T8 298-303 protein denotes Smad6
T9 308-313 protein denotes Smad7
T10 318-352 protein denotes human bone morphogenetic protein-2
T11 354-360 protein denotes hBMP-2
T12 387-393 protein denotes hBMP-2
T13 433-455 cell_line denotes mouse B cell hybridoma
T14 456-467 cell_line denotes HS-72 cells
T15 524-529 protein denotes Smad6
T16 534-539 protein denotes Smad7
T17 554-560 protein denotes hBMP-2
T18 569-580 protein denotes Smad1/Smad5
T19 626-631 protein denotes Smad7
T20 721-732 cell_line denotes HS-72 cells
T21 777-782 protein denotes Smad6
T22 811-822 cell_line denotes HS-72 cells
T23 824-829 protein denotes Smad6
T24 960-965 protein denotes Smad7
T25 975-980 protein denotes Smad6
T26 1039-1050 cell_line denotes HS-72 cells
T27 1058-1063 protein denotes Smad6
T28 1068-1073 protein denotes Smad7
T29 1183-1198 cell_type denotes B lineage cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-134 Sentence denotes Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells.
S2 135-267 Sentence denotes Smad6 and Smad7 prevent ligand-induced activation of signal-transducing Smad proteins in the transforming growth factor-beta family.
S3 268-468 Sentence denotes Here we demonstrate that both Smad6 and Smad7 are human bone morphogenetic protein-2 (hBMP-2)-inducible antagonists of hBMP-2-induced growth arrest and apoptosis in mouse B cell hybridoma HS-72 cells.
S4 469-597 Sentence denotes Moreover, we confirmed that the ectopic expressions of Smad6 and Smad7 inhibited the hBMP-2-induced Smad1/Smad5 phosphorylation.
S5 598-733 Sentence denotes We previously reported that Smad7 is an activin A-inducible antagonist of activin A-induced growth arrest and apoptosis in HS-72 cells.
S6 734-909 Sentence denotes Interestingly, although mRNA expression of Smad6 was induced by activin A in HS-72 cells, Smad6 showed no antagonistic effect on activin A-induced growth arrest and apoptosis.
S7 910-1051 Sentence denotes Moreover, we found that the ectopic expression of Smad7, but not Smad6, inhibited the activin A-induced Smad2 phosphorylation in HS-72 cells.
S8 1052-1199 Sentence denotes Thus, Smad6 and Smad7 exhibit differential inhibitory effects in bone morphogenetic protein-2- and activin A-mediated signaling in B lineage cells.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C2 27-32 NP denotes Smad6
C3 37-42 NP denotes Smad7
C1 27-42 NP denotes Smad6 and Smad7
C4 113-122 NP denotes apoptosis
C6 135-140 NP denotes Smad6
C7 145-150 NP denotes Smad7
C5 135-150 NP denotes Smad6 and Smad7
C8 293-313 NP denotes both Smad6 and Smad7
C9 420-429 NP denotes apoptosis
C10 433-467 NP denotes mouse B cell hybridoma HS-72 cells
C12 524-529 NP denotes Smad6
C13 534-539 NP denotes Smad7
C11 524-539 NP denotes Smad6 and Smad7
C14 626-631 NP denotes Smad7
C16 708-717 NP denotes apoptosis
C15 672-717 NP denotes activin A-induced growth arrest and apoptosis
C17 721-732 NP denotes HS-72 cells
C18 777-782 NP denotes Smad6
C19 811-822 NP denotes HS-72 cells
C20 824-829 NP denotes Smad6
C22 899-908 NP denotes apoptosis
C21 863-908 NP denotes activin A-induced growth arrest and apoptosis
C23 960-965 NP denotes Smad7
C24 1039-1050 NP denotes HS-72 cells
C26 1058-1063 NP denotes Smad6
C27 1068-1073 NP denotes Smad7
C25 1058-1073 NP denotes Smad6 and Smad7
R1 C6 C2 coref-ident Smad6,Smad6
R2 C7 C3 coref-ident Smad7,Smad7
R3 C5 C1 coref-ident Smad6 and Smad7,Smad6 and Smad7
R4 C8 C5 coref-ident both Smad6 and Smad7,Smad6 and Smad7
R5 C9 C4 coref-ident apoptosis,apoptosis
R6 C12 C6 coref-ident Smad6,Smad6
R7 C13 C7 coref-ident Smad7,Smad7
R8 C11 C8 coref-ident Smad6 and Smad7,both Smad6 and Smad7
R9 C14 C13 coref-ident Smad7,Smad7
R10 C16 C9 coref-ident apoptosis,apoptosis
R11 C17 C10 coref-ident HS-72 cells,mouse B cell hybridoma HS-72 cells
R12 C18 C12 coref-ident Smad6,Smad6
R13 C19 C17 coref-ident HS-72 cells,HS-72 cells
R14 C20 C18 coref-ident Smad6,Smad6
R15 C22 C16 coref-ident apoptosis,apoptosis
R16 C21 C15 coref-ident activin A-induced growth arrest and apoptosis,activin A-induced growth arrest and apoptosis
R17 C23 C14 coref-ident Smad7,Smad7
R18 C24 C19 coref-ident HS-72 cells,HS-72 cells
R19 C26 C20 coref-ident Smad6,Smad6
R20 C27 C23 coref-ident Smad7,Smad7
R21 C25 C11 coref-ident Smad6 and Smad7,Smad6 and Smad7

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 27-32 protein_molecule denotes Smad6
T2 37-42 protein_molecule denotes Smad7
T3 113-122 other_name denotes apoptosis
T4 126-133 cell_type denotes B cells
T5 135-140 protein_molecule denotes Smad6
T6 145-150 protein_molecule denotes Smad7
T7 188-220 protein_family_or_group denotes signal-transducing Smad proteins
T8 228-266 protein_family_or_group denotes transforming growth factor-beta family
T9 298-303 protein_molecule denotes Smad6
T10 308-313 protein_molecule denotes Smad7
T11 318-352 protein_molecule denotes human bone morphogenetic protein-2
T12 354-360 protein_molecule denotes hBMP-2
T13 387-393 protein_molecule denotes hBMP-2
T14 420-429 other_name denotes apoptosis
T15 433-455 cell_line denotes mouse B cell hybridoma
T16 456-467 cell_line denotes HS-72 cells
T17 524-529 protein_molecule denotes Smad6
T18 534-539 protein_molecule denotes Smad7
T19 554-560 protein_molecule denotes hBMP-2
T20 569-580 protein_molecule denotes Smad1/Smad5
T21 626-631 protein_molecule denotes Smad7
T22 708-717 other_name denotes apoptosis
T23 721-732 cell_line denotes HS-72 cells
T24 758-773 other_name denotes mRNA expression
T25 777-782 protein_molecule denotes Smad6
T26 798-807 other_organic_compound denotes activin A
T27 811-822 cell_line denotes HS-72 cells
T28 824-829 protein_molecule denotes Smad6
T29 863-872 other_organic_compound denotes activin A
T30 899-908 other_name denotes apoptosis
T31 938-956 other_name denotes ectopic expression
T32 960-965 protein_molecule denotes Smad7
T33 975-980 protein_molecule denotes Smad6
T34 996-1005 other_organic_compound denotes activin A
T35 1039-1050 cell_line denotes HS-72 cells
T36 1058-1063 protein_molecule denotes Smad6
T37 1068-1073 protein_molecule denotes Smad7
T38 1095-1113 other_name denotes inhibitory effects
T39 1183-1198 cell_type denotes B lineage cells

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 46-50 Body_part denotes bone http://purl.obolibrary.org/obo/MAT_0000299
T2 324-328 Body_part denotes bone http://purl.obolibrary.org/obo/MAT_0000299
T3 1117-1121 Body_part denotes bone http://purl.obolibrary.org/obo/MAT_0000299

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 318-323 OrganismTaxon denotes human 9606
T2 433-438 OrganismTaxon denotes mouse 10088|10090

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 46-50 Body_part denotes bone http://purl.obolibrary.org/obo/UBERON_0001474|http://purl.obolibrary.org/obo/UBERON_0002481
T3 324-328 Body_part denotes bone http://purl.obolibrary.org/obo/UBERON_0001474|http://purl.obolibrary.org/obo/UBERON_0002481
T5 439-445 Body_part denotes B cell http://purl.obolibrary.org/obo/CL_0000236
T6 1117-1121 Body_part denotes bone http://purl.obolibrary.org/obo/UBERON_0001474|http://purl.obolibrary.org/obo/UBERON_0002481

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 126-133 Cell denotes B cells http://purl.obolibrary.org/obo/CL:0000236
T2 439-445 Cell denotes B cell http://purl.obolibrary.org/obo/CL:0000236