| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-48 |
Sentence |
denotes |
Plasma protein glycation in Alzheimer's disease. |
| TextSentencer_T2 |
49-204 |
Sentence |
denotes |
Recent studies have suggested that formation of advanced glycation end-products (AGEs) in some brain proteins could be associated with Alzheimer's disease. |
| TextSentencer_T3 |
205-320 |
Sentence |
denotes |
These AGEs can be produced by various sugars (hexose, pentose, glyceraldehyde and oxidative products of vitamin C). |
| TextSentencer_T4 |
321-491 |
Sentence |
denotes |
In this study, we quantified plasma protein glycation specifically derived from glucose in patients with Alzheimer's disease with different grades of cognitive disorders. |
| TextSentencer_T5 |
492-760 |
Sentence |
denotes |
Two groups of Alzheimer patients were studied: a group with moderate Alzheimer's disease (n = 6, 9<MMS<20) and a severe Alzheimer group (n = 13, MMS<9) who were compared with an age-matched control group (n = 10, MMS>23) and a group of subjects with diabetes (n = 31). |
| TextSentencer_T6 |
761-1094 |
Sentence |
denotes |
Protein glycation was evaluated in plasma with a highly specific HPLC-UV technique, using furosine, which is the acid hydrolysis product of epsilon-deoxy-fructosyl-lysine Plasma furosine was almost two times higher in subjects with Alzheimer's disease (p<.005) than in controls, but still 50% lower than in diabetic patients (P<.02). |
| TextSentencer_T7 |
1095-1185 |
Sentence |
denotes |
Fasting plasma glucose levels were significantly correlated to the furosine concentration. |
| TextSentencer_T8 |
1186-1357 |
Sentence |
denotes |
To explain these results, an eventual impairment in glucose peripheral use or an increase in protein glycation rate associated with Alzheimer's disease should be explored. |
| T1 |
0-48 |
Sentence |
denotes |
Plasma protein glycation in Alzheimer's disease. |
| T2 |
49-204 |
Sentence |
denotes |
Recent studies have suggested that formation of advanced glycation end-products (AGEs) in some brain proteins could be associated with Alzheimer's disease. |
| T3 |
205-320 |
Sentence |
denotes |
These AGEs can be produced by various sugars (hexose, pentose, glyceraldehyde and oxidative products of vitamin C). |
| T4 |
321-491 |
Sentence |
denotes |
In this study, we quantified plasma protein glycation specifically derived from glucose in patients with Alzheimer's disease with different grades of cognitive disorders. |
| T5 |
492-760 |
Sentence |
denotes |
Two groups of Alzheimer patients were studied: a group with moderate Alzheimer's disease (n = 6, 9<MMS<20) and a severe Alzheimer group (n = 13, MMS<9) who were compared with an age-matched control group (n = 10, MMS>23) and a group of subjects with diabetes (n = 31). |
| T6 |
761-1094 |
Sentence |
denotes |
Protein glycation was evaluated in plasma with a highly specific HPLC-UV technique, using furosine, which is the acid hydrolysis product of epsilon-deoxy-fructosyl-lysine Plasma furosine was almost two times higher in subjects with Alzheimer's disease (p<.005) than in controls, but still 50% lower than in diabetic patients (P<.02). |
| T7 |
1095-1185 |
Sentence |
denotes |
Fasting plasma glucose levels were significantly correlated to the furosine concentration. |
| T8 |
1186-1357 |
Sentence |
denotes |
To explain these results, an eventual impairment in glucose peripheral use or an increase in protein glycation rate associated with Alzheimer's disease should be explored. |
