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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 35-77 cell_type denotes human CD34+ hematopoietic progenitor cells
T2 94-117 protein denotes retinoic acid receptors
T3 122-142 protein denotes retinoid X receptors
T4 180-210 cell_type denotes hematopoietic progenitor cells
T5 283-302 cell_type denotes hematopoietic cells
T6 380-422 cell_type denotes human CD34+ hematopoietic progenitor cells
T7 510-520 cell_type denotes dead cells
T8 579-592 cell_type denotes control cells
T9 1004-1041 protein denotes granulocyte colony-stimulating factor
T10 1051-1099 protein denotes granulocyte-macrophage colony-stimulating factor
T11 1129-1140 cell_type denotes CD34+ cells
T12 1202-1207 protein denotes G-CSF
T13 1212-1218 protein denotes GM-CSF
T14 1222-1233 cell_type denotes CD34+ cells
T15 1235-1240 protein denotes G-CSF
T16 1245-1255 cell_type denotes dead cells
T17 1266-1271 protein denotes G-CSF
T18 1283-1289 protein denotes GM-CSF
T19 1296-1302 protein denotes GM-CSF
T20 1349-1360 cell_type denotes CD34+ cells
T21 1365-1381 cell_type denotes CD34+CD71+ cells
T22 1398-1412 protein denotes erythropoietin
T23 1521-1544 protein denotes retinoic acid receptors
T24 1567-1587 protein denotes retinoid X receptors
T25 1589-1593 protein denotes RXRs
T26 1622-1626 protein denotes RARs
T27 1703-1707 protein denotes RARs
T28 1719-1723 protein denotes RXRs
T29 1766-1792 cell_type denotes erythroid progenitor cells

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-211 Sentence denotes Retinoic acid induces apoptosis of human CD34+ hematopoietic progenitor cells: involvement of retinoic acid receptors and retinoid X receptors depends on lineage commitment of the hematopoietic progenitor cells.
S2 212-303 Sentence denotes Retinoids are bifunctional regulators of growth and differentiation of hematopoietic cells.
S3 304-456 Sentence denotes In this study we explored the effects of retinoic acid (RA) on apoptosis of human CD34+ hematopoietic progenitor cells isolated from normal bone marrow.
S4 457-618 Sentence denotes RA (100 nM) induced an increase in the percentage of dead cells from 24% to 44% at day 6 (p < 0.05, n = 6) as compared to control cells cultured in medium alone.
S5 619-678 Sentence denotes The effect was dose dependent and appeared relatively late.
S6 679-735 Sentence denotes Significant differences were observed from day 4 onward.
S7 736-968 Sentence denotes Apoptosis, or programmed cell death, was demonstrated as the mode of cell death by using the TUNEL assay, which detects single strand nicks in DNA, or by the Nicoletti technique demonstrating a subdiploid population by DNA staining.
S8 969-1141 Sentence denotes RA previously was found to inhibit granulocyte colony-stimulating factor--and not granulocyte-macrophage colony-stimulating factor--stimulated proliferation of CD34+ cells.
S9 1142-1314 Sentence denotes However, we found that RA opposed anti-apoptotic effects of G-CSF and GM-CSF on CD34+ cells (G-CSF: 8% dead cells at day 6; G-CSF + RA: 20%; GM-CSF: 12%; GM-CSF + RA: 27%).
S10 1315-1413 Sentence denotes Moreover, RA induced apoptosis of CD34+ cells and CD34+CD71+ cells stimulated with erythropoietin.
S11 1414-1607 Sentence denotes To explore the receptor signaling pathways involved in RA-induced apoptosis, we used selective ligands for retinoic acid receptors (RARs; RO13-7410) and retinoid X receptors (RXRs; RO 25-6603).
S12 1608-1793 Sentence denotes We found that RARs were involved in RA-mediated apoptosis of myeloid progenitor cells, whereas RARs as well as RXRs were involved in RA-mediated apoptosis of erythroid progenitor cells.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-13 NP denotes Retinoic acid
C2 35-77 NP denotes human CD34+ hematopoietic progenitor cells
C4 94-117 NP denotes retinoic acid receptors
C5 122-142 NP denotes retinoid X receptors
C3 94-142 NP denotes retinoic acid receptors and retinoid X receptors
C6 176-210 NP denotes the hematopoietic progenitor cells
C7 345-363 NP denotes retinoic acid (RA)
C8 736-745 NP denotes Apoptosis
C9 750-771 NP denotes programmed cell death
C10 825-840 NP denotes the TUNEL assay
C11 842-847 NP denotes which
C12 969-971 NP denotes RA
C13 1129-1140 NP denotes CD34+ cells
C14 1165-1167 NP denotes RA
C15 1222-1233 NP denotes CD34+ cells
C16 1325-1327 NP denotes RA
C17 1349-1360 NP denotes CD34+ cells
C18 1521-1544 NP denotes retinoic acid receptors
C19 1567-1587 NP denotes retinoid X receptors
C20 1622-1626 NP denotes RARs
C22 1703-1707 NP denotes RARs
C23 1719-1723 NP denotes RXRs
C21 1703-1723 NP denotes RARs as well as RXRs
R1 C6 C2 coref-ident the hematopoietic progenitor cells,human CD34+ hematopoietic progenitor cells
R2 C7 C1 coref-ident retinoic acid (RA),Retinoic acid
R3 C9 C8 coref-ident programmed cell death,Apoptosis
R4 C11 C10 coref-relat which,the TUNEL assay
R5 C12 C7 coref-ident RA,retinoic acid (RA)
R6 C14 C12 coref-ident RA,RA
R7 C15 C13 coref-ident CD34+ cells,CD34+ cells
R8 C16 C14 coref-ident RA,RA
R9 C17 C15 coref-ident CD34+ cells,CD34+ cells
R10 C18 C4 coref-ident retinoic acid receptors,retinoic acid receptors
R11 C19 C5 coref-ident retinoid X receptors,retinoid X receptors
R12 C20 C18 coref-ident RARs,retinoic acid receptors
R13 C22 C20 coref-ident RARs,RARs
R14 C23 C19 coref-ident RXRs,retinoid X receptors
R15 C21 C3 coref-ident RARs as well as RXRs,retinoic acid receptors and retinoid X receptors

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-13 other_organic_compound denotes Retinoic acid
T2 22-31 other_name denotes apoptosis
T3 35-77 cell_type denotes human CD34+ hematopoietic progenitor cells
T4 94-117 protein_family_or_group denotes retinoic acid receptors
T5 122-142 protein_family_or_group denotes retinoid X receptors
T6 180-210 cell_type denotes hematopoietic progenitor cells
T7 226-249 other_name denotes bifunctional regulators
T8 283-302 cell_type denotes hematopoietic cells
T9 345-358 other_organic_compound denotes retinoic acid
T10 360-362 other_organic_compound denotes RA
T11 367-376 other_name denotes apoptosis
T12 380-391 cell_type denotes human CD34+
T13 392-422 cell_type denotes hematopoietic progenitor cells
T14 457-459 other_organic_compound denotes RA
T15 510-520 cell_type denotes dead cells
T16 579-592 cell_type denotes control cells
T17 605-611 other_organic_compound denotes medium
T18 736-745 other_name denotes Apoptosis
T19 750-771 other_name denotes programmed cell death
T20 805-815 other_name denotes cell death
T21 829-840 other_name denotes TUNEL assay
T22 894-913 other_name denotes Nicoletti technique
T23 930-951 other_name denotes subdiploid population
T24 955-967 other_name denotes DNA staining
T25 969-971 other_organic_compound denotes RA
T26 1004-1041 protein_family_or_group denotes granulocyte colony-stimulating factor
T27 1051-1099 protein_family_or_group denotes granulocyte-macrophage colony-stimulating factor
T28 1129-1140 cell_type denotes CD34+ cells
T29 1165-1167 other_organic_compound denotes RA
T30 1176-1198 other_name denotes anti-apoptotic effects
T31 1202-1207 protein_family_or_group denotes G-CSF
T32 1212-1218 protein_family_or_group denotes GM-CSF
T33 1222-1233 cell_type denotes CD34+ cells
T34 1235-1240 protein_family_or_group denotes G-CSF
T35 1245-1255 cell_type denotes dead cells
T36 1266-1271 protein_family_or_group denotes G-CSF
T37 1274-1276 other_organic_compound denotes RA
T38 1283-1289 protein_family_or_group denotes GM-CSF
T39 1296-1302 protein_family_or_group denotes GM-CSF
T40 1305-1307 other_organic_compound denotes RA
T41 1325-1327 other_organic_compound denotes RA
T42 1336-1345 other_name denotes apoptosis
T43 1349-1360 cell_type denotes CD34+ cells
T44 1365-1381 cell_type denotes CD34+CD71+ cells
T45 1398-1412 protein_molecule denotes erythropoietin
T46 1429-1456 other_name denotes receptor signaling pathways
T47 1469-1471 other_organic_compound denotes RA
T48 1480-1489 other_name denotes apoptosis
T49 1521-1534 other_organic_compound denotes retinoic acid
T50 1546-1550 other_organic_compound denotes RARs
T51 1567-1587 protein_family_or_group denotes retinoid X receptors
T52 1589-1593 protein_molecule denotes RXRs
T53 1622-1626 protein_family_or_group denotes RARs
T54 1644-1646 other_organic_compound denotes RA
T55 1656-1665 other_name denotes apoptosis
T56 1703-1707 protein_family_or_group denotes RARs
T57 1719-1723 protein_molecule denotes RXRs
T58 1741-1743 other_organic_compound denotes RA
T59 1753-1762 other_name denotes apoptosis
T60 1766-1792 cell_type denotes erythroid progenitor cells

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 510-514 HP_0000365 denotes dead
T2 1245-1249 HP_0000365 denotes dead